55X_ROI_Q1_2026
Nov 9, 3:22 PM
$SLS $ABVX
First Remission (CR1) Median Overall Survival, Absent Transplant
BAT/ SOC is Onureg / ORAL AZ - MOS is 24.7 MONTHS*
-- Adding Venetoclax to Oral AZ Failed to Increase MOS in 5 Large Trials.
-- including Failing 2 Phase 3 Trials, conducted by
$ABBV for AML Remission
• VIALE-M Failed in First Remission Transplant Ineligible AML
• VIALE-T Failed in Post Transplant Maintenance
Dr. Kantarjian of MD ANDERSON, Published REAL WORLD Data showing ADDING Venetoclax to Oral AZ for First Remission ACTUALLY LOWERED SURVIVAL in combination - MOS OF JUST 18.6 months vs 24.7.
*GPS has proven effective in Preventing Relapse and Extending Survival in ALL Previous Trials INCLUDING In 2 Phase 2 Trials for AML REMISSION PATIENTS Ineligible for Transplant
•• With a MOS > 67.6 Months in FIRST REMISSION // 67.6 vs BAT 24.7
• 21 Month MOS in Second Remission / Stat Sig, all MRD+ and Older who got less Gps immunotherapy - just 12 doses in Year 1 vs 15 Y1 doses and extended beyond in the REGAL P3.
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