Market Cap 13.11B
Revenue (ttm) 180.13M
Net Income (ttm) -465.89M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -258.64%
Debt to Equity Ratio 0.54
Volume 220,900
Avg Vol 350,842
Day's Range N/A - N/A
Shares Out 22.71M
Stochastic %K 54%
Beta -1.04
Analysts Strong Sell
Price Target $541.69

Company Profile

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company is headquartered in West Conshohocken, Pennsylvania.

Industry: Biotechnology
Sector: Healthcare
Phone: 267 824 2827
Address:
Four Tower Bridge, Suite 200 200 Barr Harbor Drive, West Conshohocken, United States
BioRich
BioRich Dec. 7 at 4:33 AM
$ALT For those new here, PermaPumpers on this board have zero concept of the current state of $ALT. A fun argument they make is that the "Placebo arm abnormally performed well". What they are failing to realize is what everyone else (BP, FDA, SEC, MMs, WS, etc.) sees; $ALT's Pemvi failed to show improvement in Fibrosis without worsening of MASH. Period. They ran the trial, the got the results, the results PROVED Pemvi didn't work for the Primary Endpoint (hence the 60% drop). For fun, $ALT highlights that their Placebo dose did better for Fibrosis Improvement than $ETNB and $MDGL drug arms. Folks, I can't make this up. Look below. That was $ALT's make or break. Even the biggest pumpers now admitted it then. $ALT failed. They go to the FDA with 50% of their primary endpoints for MASH P2b as FAILED. If you have questions, ask. The Bull volume here wants you to forget the facts and reality so they can fool you to buy (to cover their losses). Cheers!
1 · Reply
FatMoneyScience
FatMoneyScience Dec. 6 at 10:58 PM
$ALT When $MDGL started Phase 3, they had a market cap of ~$1.9 Billion (~$125/share) with only ~3,354 weeks of patient safety exposure to resmetirom. Altimmune will soon be entering Phase 3 with ~22,400 weeks of patient safety exposure to pemvidutide (over 6.5x more data than MDGL had). Yet, it trades at roughly 1/4th the valuation MDGL commanded at the same milestone. Market cap adjustment coming soon, IMO.
0 · Reply
biolover
biolover Dec. 6 at 8:07 PM
$ALT $MDGL $VKTX Your lead guy on Alt trial is biased by personal gain. U don’t need to lecture people who know this shit.
1 · Reply
Caw1994
Caw1994 Dec. 6 at 7:59 PM
$ALT $VKTX $MDGL We are all very concerned about this too... 😂😂 Isn't it great that the only people that question Pemvi's data is stocktwit users? Not KOL's or anyone in the scientific community?
5 · Reply
biolover
biolover Dec. 6 at 3:58 PM
$VKTX Most important piece of data from $GPCR trial is liver enzymes. CEO stresses importance of drug safety. $LLY orforglipron Attain 1 and Attain 2 showed imbalance that is tilted towards the higher doses ( of ALT > x10). Although both papers stated other reasons such as gallbladder disease , this can not be confirmed with confidence in Large trials. And no details re exposure. GPCR uses higher doses of same mole scaffold and thus stating no liver enzyme imbalance is critical. Same with $AZN same scaffold molecule that reported one case of increased ALT in phase 1 High liver enzyme with structure data will kill anything having to do with orfor scaffold including $MDGL and MRK preclinical deals from China Hope I am wrong as will be another option for people who hate needles and honestly different segment as all this class has no competitive position against dual agonist injectables.
0 · Reply
biolover
biolover Dec. 6 at 3:52 PM
$ALT $VKTX I went yesterday through Lancet paper. Never seen low quality lancet pub like this one. Terrible supplement. Not much data on toxicity .. shame on lancet editors. They are dying to get a MASH or obesity ( hottest medical topic now ) pub as they are missing on all key FDA approval papers to NEJM. Also Garg probably intended to do Bx at 24 vs 52 wks to keep investors hung on hope the inferior mash resolution vs tirzepatide ( or even semaglutide) would get better with time ( which is not true.. as MASh resolution is not fibrosis ) People who encroach on medical topics continue to compare with lousy $MDGL drug data and forget what is coming to MASH soon. ..:
4 · Reply
PrivateProfiteersAnalyst
PrivateProfiteersAnalyst Dec. 6 at 2:22 AM
Actionable Trade Alert for $MDGL: Market Context: $MDGL is currently trading at $586.21, showing strong momentum with an RSI of 72.17, indicating overbought conditions. The price is above both the 30-day MA of $511.81 and the 50-day MA of $481.67, suggesting bullish sentiment in the short to medium term. Directional Bias: Given the recent high of $605.0 and the low of $393.61 over the last 60 days, we anticipate a potential pullback or consolidation before further upward movement. The ATR of 27.15 indicates volatility, allowing for significant price swings. Trade Plan: - Suggested Entry: $586.21 - Stop Loss: $570.00 (approx. 2.8% below entry) - Take Profit Targets: 1. $605.00 (3.2% gain) 2. $620.00 (5.8% gain) 3. $685.00 (16.8% gain) Target 3 offers a potential ROI of over 17%. Monitor RSI for signs of reversal and adjust targets accordingly. https://privateprofiteers.com
0 · Reply
PrivateProfiteersAnalyst
PrivateProfiteersAnalyst Dec. 5 at 9:57 PM
Actionable Trade Alert for $MDGL: Market Context: $MDGL is currently trading at $586.21, showing strong momentum with an RSI of 72.17, indicating overbought conditions. The price is above both the 30-day MA of $511.81 and the 50-day MA of $481.67, suggesting bullish sentiment in the short to medium term. Directional Bias: Given the recent high of $605.0 and the low of $393.61 over the last 60 days, we anticipate a potential pullback or consolidation before further upward movement. The ATR of 27.15 indicates volatility, allowing for significant price swings. Trade Plan: - Suggested Entry: $586.21 - Stop Loss: $570.00 (approx. 2.8% below entry) - Take Profit Targets: 1. $605.00 (3.2% gain) 2. $620.00 (5.8% gain) 3. $685.00 (16.8% gain) Target 3 offers a potential ROI of over 17%. Monitor RSI for signs of reversal and adjust targets accordingly. https://privateprofiteers.com
0 · Reply
forprofit12
forprofit12 Dec. 5 at 8:04 PM
$SGMT added. With $MDGL being my largest position and biggest winner so far, this seems like a steal at these prices.
0 · Reply
Wallst45
Wallst45 Dec. 5 at 7:13 PM
$MDGL just BTFD
0 · Reply
Latest News on MDGL
Madrigal (MDGL) Q2 Revenue Soars 1,313%

Aug 5, 2025, 4:07 PM EDT - 4 months ago

Madrigal (MDGL) Q2 Revenue Soars 1,313%


Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra

May 6, 2025, 4:20 PM EDT - 7 months ago

Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra


Madrigal Appoints Jacqualyn A. Fouse, Ph.D.

Mar 11, 2025, 8:00 AM EDT - 9 months ago

Madrigal Appoints Jacqualyn A. Fouse, Ph.D.


Madrigal CEO on Q4 earnings beat, MASH drug market opportunity

Feb 26, 2025, 6:33 PM EST - 10 months ago

Madrigal CEO on Q4 earnings beat, MASH drug market opportunity


Why Madrigal Pharmaceuticals Stock Is Soaring Today

Feb 26, 2025, 11:27 AM EST - 10 months ago

Why Madrigal Pharmaceuticals Stock Is Soaring Today


BioRich
BioRich Dec. 7 at 4:33 AM
$ALT For those new here, PermaPumpers on this board have zero concept of the current state of $ALT. A fun argument they make is that the "Placebo arm abnormally performed well". What they are failing to realize is what everyone else (BP, FDA, SEC, MMs, WS, etc.) sees; $ALT's Pemvi failed to show improvement in Fibrosis without worsening of MASH. Period. They ran the trial, the got the results, the results PROVED Pemvi didn't work for the Primary Endpoint (hence the 60% drop). For fun, $ALT highlights that their Placebo dose did better for Fibrosis Improvement than $ETNB and $MDGL drug arms. Folks, I can't make this up. Look below. That was $ALT's make or break. Even the biggest pumpers now admitted it then. $ALT failed. They go to the FDA with 50% of their primary endpoints for MASH P2b as FAILED. If you have questions, ask. The Bull volume here wants you to forget the facts and reality so they can fool you to buy (to cover their losses). Cheers!
1 · Reply
FatMoneyScience
FatMoneyScience Dec. 6 at 10:58 PM
$ALT When $MDGL started Phase 3, they had a market cap of ~$1.9 Billion (~$125/share) with only ~3,354 weeks of patient safety exposure to resmetirom. Altimmune will soon be entering Phase 3 with ~22,400 weeks of patient safety exposure to pemvidutide (over 6.5x more data than MDGL had). Yet, it trades at roughly 1/4th the valuation MDGL commanded at the same milestone. Market cap adjustment coming soon, IMO.
0 · Reply
biolover
biolover Dec. 6 at 8:07 PM
$ALT $MDGL $VKTX Your lead guy on Alt trial is biased by personal gain. U don’t need to lecture people who know this shit.
1 · Reply
Caw1994
Caw1994 Dec. 6 at 7:59 PM
$ALT $VKTX $MDGL We are all very concerned about this too... 😂😂 Isn't it great that the only people that question Pemvi's data is stocktwit users? Not KOL's or anyone in the scientific community?
5 · Reply
biolover
biolover Dec. 6 at 3:58 PM
$VKTX Most important piece of data from $GPCR trial is liver enzymes. CEO stresses importance of drug safety. $LLY orforglipron Attain 1 and Attain 2 showed imbalance that is tilted towards the higher doses ( of ALT > x10). Although both papers stated other reasons such as gallbladder disease , this can not be confirmed with confidence in Large trials. And no details re exposure. GPCR uses higher doses of same mole scaffold and thus stating no liver enzyme imbalance is critical. Same with $AZN same scaffold molecule that reported one case of increased ALT in phase 1 High liver enzyme with structure data will kill anything having to do with orfor scaffold including $MDGL and MRK preclinical deals from China Hope I am wrong as will be another option for people who hate needles and honestly different segment as all this class has no competitive position against dual agonist injectables.
0 · Reply
biolover
biolover Dec. 6 at 3:52 PM
$ALT $VKTX I went yesterday through Lancet paper. Never seen low quality lancet pub like this one. Terrible supplement. Not much data on toxicity .. shame on lancet editors. They are dying to get a MASH or obesity ( hottest medical topic now ) pub as they are missing on all key FDA approval papers to NEJM. Also Garg probably intended to do Bx at 24 vs 52 wks to keep investors hung on hope the inferior mash resolution vs tirzepatide ( or even semaglutide) would get better with time ( which is not true.. as MASh resolution is not fibrosis ) People who encroach on medical topics continue to compare with lousy $MDGL drug data and forget what is coming to MASH soon. ..:
4 · Reply
PrivateProfiteersAnalyst
PrivateProfiteersAnalyst Dec. 6 at 2:22 AM
Actionable Trade Alert for $MDGL: Market Context: $MDGL is currently trading at $586.21, showing strong momentum with an RSI of 72.17, indicating overbought conditions. The price is above both the 30-day MA of $511.81 and the 50-day MA of $481.67, suggesting bullish sentiment in the short to medium term. Directional Bias: Given the recent high of $605.0 and the low of $393.61 over the last 60 days, we anticipate a potential pullback or consolidation before further upward movement. The ATR of 27.15 indicates volatility, allowing for significant price swings. Trade Plan: - Suggested Entry: $586.21 - Stop Loss: $570.00 (approx. 2.8% below entry) - Take Profit Targets: 1. $605.00 (3.2% gain) 2. $620.00 (5.8% gain) 3. $685.00 (16.8% gain) Target 3 offers a potential ROI of over 17%. Monitor RSI for signs of reversal and adjust targets accordingly. https://privateprofiteers.com
0 · Reply
PrivateProfiteersAnalyst
PrivateProfiteersAnalyst Dec. 5 at 9:57 PM
Actionable Trade Alert for $MDGL: Market Context: $MDGL is currently trading at $586.21, showing strong momentum with an RSI of 72.17, indicating overbought conditions. The price is above both the 30-day MA of $511.81 and the 50-day MA of $481.67, suggesting bullish sentiment in the short to medium term. Directional Bias: Given the recent high of $605.0 and the low of $393.61 over the last 60 days, we anticipate a potential pullback or consolidation before further upward movement. The ATR of 27.15 indicates volatility, allowing for significant price swings. Trade Plan: - Suggested Entry: $586.21 - Stop Loss: $570.00 (approx. 2.8% below entry) - Take Profit Targets: 1. $605.00 (3.2% gain) 2. $620.00 (5.8% gain) 3. $685.00 (16.8% gain) Target 3 offers a potential ROI of over 17%. Monitor RSI for signs of reversal and adjust targets accordingly. https://privateprofiteers.com
0 · Reply
forprofit12
forprofit12 Dec. 5 at 8:04 PM
$SGMT added. With $MDGL being my largest position and biggest winner so far, this seems like a steal at these prices.
0 · Reply
Wallst45
Wallst45 Dec. 5 at 7:13 PM
$MDGL just BTFD
0 · Reply
Twisty_Corn
Twisty_Corn Dec. 5 at 6:54 PM
$ALT $MDGL Dude, @Designed2Gain are you this dumb and pathetic? You reposted $ALT PLACEBO did better than 89Bio and MDGL. How...I mean, how do you expect anyone to take you serious? And yes, I watch all of these people you listed, but @BioRich runs circles around any of these people with real information. Yeah, he posts a shit ton, but he's laid it all out. I use the Mute button when I need peace, but always go back to see what he posts. Do like me. You don't have to feed him, but at least read his posts. He's 3 steps ahead of you guys and then you guys look dumb posting obsolete debunked bullshit. Twisty Rant Out...
1 · Reply
MoneyGroupLLC
MoneyGroupLLC Dec. 5 at 2:11 PM
Enter: $MDGL Calls Strike Price: $590 Expiry Date: JAN 16 2026 Buy in Price: $42.00 - $46.40 Sell Price: $72.24 Profit : +72% (Turn every $1 into $1.72) Want Profitable Real-Time Options Alerts? 👉 https://moneygroup.us
0 · Reply
1986iamwallstreet
1986iamwallstreet Dec. 5 at 6:53 AM
$MDGL Buyout is coming ……….
0 · Reply
Wallst45
Wallst45 Dec. 5 at 5:50 AM
$MDGL just get that buyout
0 · Reply
revuelto
revuelto Dec. 5 at 3:59 AM
$MDGL some names you just hold with conviction✌️
0 · Reply
biolover
biolover Dec. 4 at 9:24 PM
$MDGL $VKTX Told people here between now and 2027 ( could happen tomorrow or post trial data ) Viking MC will be higher than MDGl likely more than double. And if not happen I am getting out of here and investment. Just due to this stupid oral GLP1 comment ( that I exactly predicted MDGl to do as some of you recall )
3 · Reply
Apopka_FL_Degenerate
Apopka_FL_Degenerate Dec. 4 at 8:37 PM
$VKTX Madrigal looking for an oral GLP-1 ???? $MDGL
2 · Reply
oneyedjacks
oneyedjacks Dec. 4 at 7:22 PM
$ALT $MDGL need one more chart showing companies with MASH resolution at 24 wks AND >10% weightloss. That chart would show Alimmune alone
1 · Reply
TrialWatcher
TrialWatcher Dec. 4 at 7:00 PM
$ALT $MDGL Madrigal is a 10 bagger in 3 years. You don’t think that or more can come to Altimmune? They went from $1.3b to 13b in 3 years. Whats $500M marketcap Altimmune at $13B? $140 stock price? Gtfo!!!
4 · Reply
Wallst45
Wallst45 Dec. 4 at 6:57 PM
$MDGL any news ???
1 · Reply
GreenEnergy2022
GreenEnergy2022 Dec. 4 at 4:46 PM
$ALT $MDGL 13,5B mcap, no weight loss, only MASH - drug is approved. Our data is better, and thats in 24w vs 52w. + we got weight loss in the same molecule since its a GLP1
0 · Reply
BioRich
BioRich Dec. 4 at 4:21 PM
$XBI $ALT ***I CAN NOT EMPHASIZE THIS ENOUGH*** Following review of publicly available information, it appears that $ALT has now acknowledged that they: DID NOT PHYSICALLY DOSE AT LEAST ONE SUBJECT WITH WHAT THEY SAID THEY DID; THEY DOSED THEM WITH SOMETHING ELSE. This was discovered AFTER $ALT publicly published (and filed with the SEC) their (now questionable) dosing confirmation. From a process control, accountability and traceability standpoint, this is a significant concern IMHO. Short of it - $ALT is changing their tune on what PHYSICALLY happened. Before arguing, let that sink it. Data discussion is one thing. Changing what PHYSICALLY happened in the trial is another stratosphere of concern. (My observation from reviewing publicly available information. Further discussion/explanation available upon request). Cheers! $VKTX $MDGL $SNY
1 · Reply