Market Cap 10.09B
Revenue (ttm) 958.40M
Net Income (ttm) -288.28M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 873.64
Profit Margin -30.08%
Debt to Equity Ratio 0.56
Volume 474,500
Avg Vol 356,294
Day's Range N/A - N/A
Shares Out 22.94M
Stochastic %K 15%
Beta -1.01
Analysts Strong Sell
Price Target $649.00

Company Profile

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company is headquartered in West Conshohocken, Pennsylvania.

Industry: Biotechnology
Sector: Healthcare
Phone: 267 824 2827
Address:
Four Tower Bridge, Suite 200 200 Barr Harbor Drive, West Conshohocken, United States
Biotech_Beast
Biotech_Beast Feb. 25 at 10:16 AM
This name has in-licensed a whole pipeline, I took a look. $MDGL https://seekingalpha.com/article/4874320-madrigal-the-easiest-money-may-have-been-made
0 · Reply
JoeB07
JoeB07 Feb. 24 at 7:02 PM
$MDGL getting close to the first long term trendline. Still in the down channel. Looks like it's bouncing. We shall see if it's ready or not.
0 · Reply
Live2ride
Live2ride Feb. 24 at 4:15 PM
$AXSM $MDGL , play your games Wall Street. I will hold and add both until we get bought out or double from here. Either way, you are not getting my shares.
2 · Reply
All_just_a_game
All_just_a_game Feb. 23 at 9:03 PM
$MDGL Sold the December 350 Puts. No liquidity but someone bought the 10 contracts lol.
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wjmax
wjmax Feb. 23 at 8:08 PM
$SLS $MDGL $NWBO Have you wondered why Baker Brothers are fond of $MDGL so much?
1 · Reply
ReapN
ReapN Feb. 23 at 7:54 PM
$SLS reminds me of $MDGL in December years back at 65 per share…. just waiting exciting times ’Another million’ Yay! Next? $NWBO building labs/facilities in UK? hmmmm always look (not go all in or fomo ) just look, read (without pictures) learn grow get better
0 · Reply
Wallst45
Wallst45 Feb. 23 at 6:28 PM
$MDGL high volumes today ??
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 23 at 5:45 PM
$MDGL https://www.biospace.com/drug-development/beyond-rezdiffra-the-4-most-promising-mash-pipelines-in-play
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forprofit12
forprofit12 Feb. 23 at 4:50 PM
$MDGL should be at least 500. Hopefully reversal soon.
0 · Reply
maybeme54
maybeme54 Feb. 23 at 4:10 PM
$MDGL Analyst Projections: Recent 12-month forecasts (as of Feb 2026) suggest a low of $469 and a high of $964.
0 · Reply
Latest News on MDGL
Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra

May 6, 2025, 4:20 PM EDT - 10 months ago

Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra


Madrigal Appoints Jacqualyn A. Fouse, Ph.D.

Mar 11, 2025, 8:00 AM EDT - 1 year ago

Madrigal Appoints Jacqualyn A. Fouse, Ph.D.


Biotech_Beast
Biotech_Beast Feb. 25 at 10:16 AM
This name has in-licensed a whole pipeline, I took a look. $MDGL https://seekingalpha.com/article/4874320-madrigal-the-easiest-money-may-have-been-made
0 · Reply
JoeB07
JoeB07 Feb. 24 at 7:02 PM
$MDGL getting close to the first long term trendline. Still in the down channel. Looks like it's bouncing. We shall see if it's ready or not.
0 · Reply
Live2ride
Live2ride Feb. 24 at 4:15 PM
$AXSM $MDGL , play your games Wall Street. I will hold and add both until we get bought out or double from here. Either way, you are not getting my shares.
2 · Reply
All_just_a_game
All_just_a_game Feb. 23 at 9:03 PM
$MDGL Sold the December 350 Puts. No liquidity but someone bought the 10 contracts lol.
0 · Reply
wjmax
wjmax Feb. 23 at 8:08 PM
$SLS $MDGL $NWBO Have you wondered why Baker Brothers are fond of $MDGL so much?
1 · Reply
ReapN
ReapN Feb. 23 at 7:54 PM
$SLS reminds me of $MDGL in December years back at 65 per share…. just waiting exciting times ’Another million’ Yay! Next? $NWBO building labs/facilities in UK? hmmmm always look (not go all in or fomo ) just look, read (without pictures) learn grow get better
0 · Reply
Wallst45
Wallst45 Feb. 23 at 6:28 PM
$MDGL high volumes today ??
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 23 at 5:45 PM
$MDGL https://www.biospace.com/drug-development/beyond-rezdiffra-the-4-most-promising-mash-pipelines-in-play
0 · Reply
forprofit12
forprofit12 Feb. 23 at 4:50 PM
$MDGL should be at least 500. Hopefully reversal soon.
0 · Reply
maybeme54
maybeme54 Feb. 23 at 4:10 PM
$MDGL Analyst Projections: Recent 12-month forecasts (as of Feb 2026) suggest a low of $469 and a high of $964.
0 · Reply
Quantumup
Quantumup Feb. 23 at 3:02 PM
H.C. Wainwright reiterated $MDGL Buy/$620 $IVA $NVO $ALGS $VKTX SGMT LLY ALT H.C. Wainwright said in its note: Rezdiffra is only seven quarters into its commercial launch and has already generated nearly $1B in net sales, an exceptional trajectory by any industry standard for a drug that created an entirely new treatment category, in our opinion. Although we acknowledge that the near-term headwinds are real, gross-to-net resets to the high 30s and 1Q seasonal reverifications create a slight trough, but we believe these are of limited consequence relative to the long-term opportunity. The diagnosed F2/F3 population has grown nearly 50% in two years to nearly 350,000 reaching a pool of approximately 470,000 to 525,000 patients with double-digit growth expected to continue, yet Rezdiffra remains under 12% penetrated, in our opinion.
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Hawksssss
Hawksssss Feb. 23 at 2:53 PM
$MDGL there was a block buy of 32k shares. That’s over 10 mil in value.
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jade100
jade100 Feb. 23 at 7:50 AM
$GYRE $MDGL https://baijiahao.baidu.com/s?id=1856906520804004398&wfr=spider&for=pc There is a chance for it to become ten times larger compared to Madrigal’s market capitalization.
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Scarlivertriumphant
Scarlivertriumphant Feb. 22 at 7:00 PM
$MDGL https://easlcampus.eu/tltm/episode-03 "Talk liver to me" EASL podcast. See 33:11 time on this Podcast. Major MASH KOLS. RESM toxicity issues? Possible DILI with alcohol? Hepatic decompensation worries? What your analysts don't tell you.
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Readytrader123
Readytrader123 Feb. 22 at 4:38 AM
$MDGL @greglr Buyout window closed. Decreasing TAM with GLP-1 penetrance- fatty liver/NASH is an endangered species. Oral wegovy just FDA approved and priced aggressively $5 a day= less NASH diagnosis over time.
1 · Reply
JoeB07
JoeB07 Feb. 20 at 11:28 PM
$MDGL on the call this week management stated they had one of their largest prescription weeks just last week. Demand for the drug is strong. The market is also growing larger as bigger players (NOVA) continue to create disease awareness. The stock is breaking out of a 16 year consolidation. Fundamentals and technicals are aligned for a major move. We can do this! Let's make some $$$$$.
0 · Reply
JoeB07
JoeB07 Feb. 20 at 8:14 PM
$MDGL Hang in there. This could be way worse, like you could be invested in software right $NOW. Or a failed study in $GRAL. This downturn will likely end the first week of March near the 200dma. I'm Ok with that. I'd like to buy one more time.
2 · Reply
TrustButVerifi
TrustButVerifi Feb. 20 at 5:03 PM
$VKTX why would anyone pay 5k per month for Rezdiffra when you can buy GLP1 for 1/10 of that ? “Wegovy (semaglutide) 2.4 mg injection received FDA accelerated approval in August 2025 for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), formerly known as NASH, in adults with moderate to advanced liver fibrosis.” $MDGL
6 · Reply
forprofit12
forprofit12 Feb. 20 at 3:37 PM
$MDGL down 30% from ATH. Brutal. Such a shame
1 · Reply
ZacksResearch
ZacksResearch Feb. 20 at 3:06 PM
Mixed Q4 for $MDGL — Is the stock's 11.1% drop justified? Q4 loss of $2.57 per share vs. expected earnings of 4 cents due to higher operating expenses. Rezdiffra sales hit $321.1M, entirely from product sales, beating expectations with significant YoY growth. See what these results mean for investors here 👉 https://www.zacks.com/stock/news/2872923/madrigal-q4-earnings-miss-mash-drug-sales-drive-top-line-stock-down?cid=sm-stocktwits-2-2872923-body-34398&ADID=SYND_STOCKTWITS_TWEET_2_2872923_BODY_34398
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JoeB07
JoeB07 Feb. 20 at 3:03 PM
$MDGL some quick notes from the call. Please let me know if I mischaracterize or miss anything: 60M payment for recent china drugs will hit books in Q1. 2026 R&D same as 2025. SGA will increase in 2026. Don't expect any contribution ex-US in 2026 (mentioned tarriffs lol). "Consensus is we expect really good 2026"--said multiple times. NOVA in the sector is leading to massive market size increases as they increase awareness. Double digit growth into the foreseeable future. Marty (CFO) states that she feels good about where the "street is" for 2026 growth. Market size is now over 400k and the company has only penetrated 8%. No discussion on when they are going to be profitable--analysts need to be better on these calls. CEO comes across as an aragant prick and is very hard to listen to. He is definitely the smartest guy in the room. He's basically doubling down on the --I'm going to build the biggest bad*ss MASH company this world has ever seen....and ...My massive pipeline is amazing!!!
1 · Reply
JoeB07
JoeB07 Feb. 20 at 2:37 PM
$MDGL Janus Henderson and Paulson both sold about 15% of their positions in Q4.
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