Market Cap 10.17B
Revenue (ttm) 958.40M
Net Income (ttm) -288.28M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -30.08%
Debt to Equity Ratio 0.56
Volume 281,900
Avg Vol 352,570
Day's Range N/A - N/A
Shares Out 22.94M
Stochastic %K 86%
Beta -0.97
Analysts Strong Sell
Price Target $653.62

Company Profile

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

Industry: Biotechnology
Sector: Healthcare
Phone: 267-824-2827
Address:
Four Tower Bridge, 200 Barr Harbor Drive Suite 200, West Conshohocken, United States
Wallst45
Wallst45 Mar. 19 at 5:35 PM
$MDGL very strong today
1 · Reply
Quantumup
Quantumup Mar. 18 at 8:22 PM
Truist🏁 $IVA Buy; $13 $LLY $MDGL $NVO $ALGS VKTX ALT Truist said:::In our view, Inventiva has a differentiated approach in MASH with near-term Ph3 data (2H26) that we think could result in up to +100% upside from current levels. IVA's lead asset lanifibranor has a unique MOA/profile among MASH therapies in development that could make it an ideal choice for a niche group of MASH patients with diabetes. We believe its path to approval is de-risked given strong Ph2 data and FDA approval of drugs w/ similar MOAs. Our model shows that base case 3L use in MASH F2/F3 supports $2.3B WW peak adj. rev w/ add'l upside if lani is used preferentially MASH+diabetes.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 18 at 7:41 PM
$MDGL holding up extremely well during these recent events.
1 · Reply
All_just_a_game
All_just_a_game Mar. 16 at 6:41 PM
$MDGL the MDGL story is still so early with so much room for growth…Baker Bros no dummies…Baker is chairman of the board…. Play the long game like Baker…add when it drops…sell some calls when it pops. Accumulate long term holdings to reduce taxes.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 16 at 12:43 PM
$MDGL I was correct in my guess!
0 · Reply
sarkar20
sarkar20 Mar. 16 at 12:24 AM
$MDGL Now I know why this beauty was down, but now this baby will rip above 600 as they got their pie!! https://www.marketbeat.com/instant-alerts/filing-madrigal-pharmaceuticals-inc-mdgl-stock-position-raised-by-baker-bros-advisors-lp-2026-03-15/
0 · Reply
balzofsteel
balzofsteel Mar. 12 at 10:24 PM
$MDGL New highs once we get thru this conflict.
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 12 at 5:53 PM
$MDGL somebody is acquiring shares today in this melt down-I wonder who?
1 · Reply
BigCheeze2014
BigCheeze2014 Mar. 12 at 1:49 PM
$MDGL Goldman is getting destroyed and this will follow
1 · Reply
BioRich
BioRich Mar. 12 at 1:27 PM
$ALT @2MargaritaLunch Chop, this kind of post is EXACTLY why the $ALT board continues to remain disconnected on $ALT's reality. Let me help: 1) Statistically, drugs that received BTD have a 65-72% probability for approval compared to 50-60% for Phase 3 drugs, overall. 46% BTDs are in Oncology. 2) Current 4 drugs in the MASH sector with BTD (Including $IVA, which leads in Fibrosis Improvement, and $SGMT, which shows excellent results with $MDGL). 3) No MASH drug that has applied for BTD has been denied. This is expected given the early stages of sector development and multiple (potential) MOAs. So thanks for sharing your hopium of success based on receiving BTD, but I think right-sizing those expecations for $ALT is more warranted than most, especially given they are significantly lagging behind excellent performing companies that are significantly further along than $ALT Cheers!
1 · Reply
Latest News on MDGL
Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra

May 6, 2025, 4:20 PM EDT - 11 months ago

Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra


Madrigal Appoints Jacqualyn A. Fouse, Ph.D.

Mar 11, 2025, 8:00 AM EDT - 1 year ago

Madrigal Appoints Jacqualyn A. Fouse, Ph.D.


Wallst45
Wallst45 Mar. 19 at 5:35 PM
$MDGL very strong today
1 · Reply
Quantumup
Quantumup Mar. 18 at 8:22 PM
Truist🏁 $IVA Buy; $13 $LLY $MDGL $NVO $ALGS VKTX ALT Truist said:::In our view, Inventiva has a differentiated approach in MASH with near-term Ph3 data (2H26) that we think could result in up to +100% upside from current levels. IVA's lead asset lanifibranor has a unique MOA/profile among MASH therapies in development that could make it an ideal choice for a niche group of MASH patients with diabetes. We believe its path to approval is de-risked given strong Ph2 data and FDA approval of drugs w/ similar MOAs. Our model shows that base case 3L use in MASH F2/F3 supports $2.3B WW peak adj. rev w/ add'l upside if lani is used preferentially MASH+diabetes.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 18 at 7:41 PM
$MDGL holding up extremely well during these recent events.
1 · Reply
All_just_a_game
All_just_a_game Mar. 16 at 6:41 PM
$MDGL the MDGL story is still so early with so much room for growth…Baker Bros no dummies…Baker is chairman of the board…. Play the long game like Baker…add when it drops…sell some calls when it pops. Accumulate long term holdings to reduce taxes.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 16 at 12:43 PM
$MDGL I was correct in my guess!
0 · Reply
sarkar20
sarkar20 Mar. 16 at 12:24 AM
$MDGL Now I know why this beauty was down, but now this baby will rip above 600 as they got their pie!! https://www.marketbeat.com/instant-alerts/filing-madrigal-pharmaceuticals-inc-mdgl-stock-position-raised-by-baker-bros-advisors-lp-2026-03-15/
0 · Reply
balzofsteel
balzofsteel Mar. 12 at 10:24 PM
$MDGL New highs once we get thru this conflict.
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 12 at 5:53 PM
$MDGL somebody is acquiring shares today in this melt down-I wonder who?
1 · Reply
BigCheeze2014
BigCheeze2014 Mar. 12 at 1:49 PM
$MDGL Goldman is getting destroyed and this will follow
1 · Reply
BioRich
BioRich Mar. 12 at 1:27 PM
$ALT @2MargaritaLunch Chop, this kind of post is EXACTLY why the $ALT board continues to remain disconnected on $ALT's reality. Let me help: 1) Statistically, drugs that received BTD have a 65-72% probability for approval compared to 50-60% for Phase 3 drugs, overall. 46% BTDs are in Oncology. 2) Current 4 drugs in the MASH sector with BTD (Including $IVA, which leads in Fibrosis Improvement, and $SGMT, which shows excellent results with $MDGL). 3) No MASH drug that has applied for BTD has been denied. This is expected given the early stages of sector development and multiple (potential) MOAs. So thanks for sharing your hopium of success based on receiving BTD, but I think right-sizing those expecations for $ALT is more warranted than most, especially given they are significantly lagging behind excellent performing companies that are significantly further along than $ALT Cheers!
1 · Reply
rational1
rational1 Mar. 12 at 12:44 PM
0 · Reply
Wallst45
Wallst45 Mar. 12 at 12:28 PM
$MDGL this will get bought out soon
0 · Reply
Quantumup
Quantumup Mar. 12 at 12:08 PM
Citizens reiterated $SGMT Market Outperform; $35 and said, We continue to like SGMT's position in MASH, with the denifanstat/resmetirom combo targeting F4 MASH, which is the highest unmet need. $MDGL $IVA NVO LLY ALGS RHHBY ALGS VKTX $BHC $DRMA BFRI Here's what else Citizens had to say: https://x.com/Quantumup1/status/2032065360715784492?s=20
0 · Reply
ReapN
ReapN Mar. 11 at 8:50 PM
Bio M&A Potential Targets Generic drug market to increase $MDGL #Mash #Nash Monopoly INSM - Lung treatment IBRX - Lung cancer Saudi Arabia SLS - AML cancer QOL NVAX - Vaccine & Adjuvant so many to choose from very
0 · Reply
Quantumup
Quantumup Mar. 11 at 8:27 PM
Oppenheimer reiterated $SGMT Outperform/$25, and said: SGMT reported 4Q25 results with $10.8M OpEx and $113.1M cash providing expected runway into 3Q27. $MDGL $IVA $NVO $ALGS VKTX RHHBY DRMA BFRI Oppenheimer added—We see key recent progress and several upcoming catalysts, including: 1) Ph1 PK study of the denifanstat plus resmetirom combination now supports a Ph2 trial in F4 MASH patients expected to initiate in 2H26; 2) partner Ascletis recently reported positive 52-week Ph3 results for denifanstat in moderate/severe acne demonstrating efficacy with favorable safety/tolerability supporting NDA filing acceptance by the Chinese NMPA, and we expect approval and launch in China ~early 2027; 3) Next-gen. FASN inhibitor TVB-3567 for acne Ph1 study data remains on track for 2026 followed by a Ph2 study pending regulatory alignment. We believe the differentiated MOA of FASN inhibition remains underappreciated while upcoming data readouts could drive upside.
0 · Reply
sarkar20
sarkar20 Mar. 10 at 9:33 PM
$MDGL Is this calm before the storm of buyout?
1 · Reply
JoeB07
JoeB07 Mar. 6 at 6:11 PM
$MDGL Nice volume on the trendline so far. Next week could get wild.
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 6 at 5:19 PM
$MDGL short interest has come way down...29%.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Mar. 6 at 5:14 PM
$MDGL I wouldn't be surprised that the BB's are buyers here lately in this zone. We will find out next month.
0 · Reply
JoeB07
JoeB07 Mar. 5 at 2:57 AM
$MDGL Mr. MM. I see the trendline has been touched. I know it was light volume and that most of the buyers are at the longer term moving averages. How about we make them chase it. Let's get this party started. Let's start tomorrow.!$!$!
0 · Reply
BioRich
BioRich Mar. 4 at 6:16 PM
$ALT More reasons why REAL INVESTORS don't believe the hYpe. This outlines why there's significant concern about $ALT's DURABILITY with Pemvi. Liver Fat Content (LFC) Reduction with trial and time: MASLD P1b (12W): 1.2mg: 46.6% LFC Reduction 1.8mg: 68.5% 2.4mg: 57.1% MASLD P1b (24W): 1.2mg: 56.3% LFC Reduction 1.8mg: 75.2% 2.4mg: 76.4% MASH P2b (24W): 1.2mg: 52% LFC Reduction 1.8mg: 57.7% MASH P2b (48W): 1.2mg: 45.2% LFC Reduction 1.8mg: 54.7% So yes, $ALT data is concerning and the durability for Pemvi is lackluster, at best. This is just one of many reasons $ALT trails $IVA (which I believe gets a deal based on Fibrosis results), $SGMT (deal with $MDGL), $MDGL and $NVO. If you organically look at the data, you'll realize why WS uses $ALT ticker as a cat toy and why $ALT (the company) has a bleak, dilution-driven future. Follow/Subscribe for more thoughts and perspective. Would love to hear yours too. That's how we learn. Cheers!
1 · Reply
ReapN
ReapN Mar. 4 at 5:33 PM
0 · Reply