Market Cap 10.87B
Revenue (ttm) 180.13M
Net Income (ttm) -465.89M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 235.85
Profit Margin -258.64%
Debt to Equity Ratio 0.54
Volume 382,800
Avg Vol 322,380
Day's Range N/A - N/A
Shares Out 22.71M
Stochastic %K 11%
Beta -1.01
Analysts Strong Sell
Price Target $647.81

Company Profile

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company is headquartered in West Conshohocken, Pennsylvania.

Industry: Biotechnology
Sector: Healthcare
Phone: 267 824 2827
Address:
Four Tower Bridge, Suite 200 200 Barr Harbor Drive, West Conshohocken, United States
SuperGreenToday
SuperGreenToday Feb. 5 at 11:49 PM
$MDGL Share Price: $463.60 Contract Selected: Jul 17, 2026 $460 Calls Buy Zone: $68.77 – $84.95 Target Zone: $109.43 – $133.75 Potential Upside: 50% ROI Time to Expiration: 161 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
forprofit12
forprofit12 Feb. 5 at 9:39 PM
$MDGL caught in the overall market crossfire. Should be fine long term
0 · Reply
JoeB07
JoeB07 Feb. 5 at 8:54 PM
$MDGL walking it down….where they gonna take it!?
0 · Reply
PashaGainz
PashaGainz Feb. 5 at 7:22 PM
$ALT BP should want ALT ASAP and today’s $HIMS news is exactly why. HIMS just came out with a dirt-cheap “Wegovy pill” alternative (compounded semaglutide) and $NVO is already talking legal action.  That’s the headline, but the bigger message is simple: obesity is turning into a price war. Margins get pressured when the market gets crowded and “cheap options” show up. So where do you keep premium economics? MASH. We literally have proof now: the first MASH drug launched with a $47.4k/year list price and even the street was modeling $30K+ pricing with $MDGL  If you’re BP, the asset you want isn’t “me too obesity.” You want the drug that can be best-in-class, Phase 3-ready, with FDA Breakthrough in MASH, plus an arsenal of other indications to stack value. Obesity alone gets commoditized. Obesity + MASH is where the real money stays. $XBI
6 · Reply
Biohub
Biohub Feb. 5 at 1:50 PM
$MDGL quality analysts have target prices significantly higher first a reason. Blockbuster drug that is still ramping up and with no opposition
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maybeme54
maybeme54 Feb. 4 at 10:59 PM
$MDGL tough start to the year here. Need some upcoming guidance and estimates to be killer! I see $700+ still by the end of the year.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 4 at 8:41 PM
$MDGL this is not the LLY board.
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ReapN
ReapN Feb. 4 at 8:18 PM
$LLY keeps a ’stranglehold on Glp’ acquires $ALT ’Pemvitude’ Superior in Weight loss. Does Phase 3 continue? Lilly lab, huge advancement in GLP technologies. (Theory) Altimmune positioning into Barbaric. see $MDGL Mash, ’Pemvitude’ multiple designations…. it could happen
0 · Reply
ChainCapital
ChainCapital Feb. 4 at 11:06 AM
$MDGL faces binary outcomes for its NASH drug resmetirom; approval and launch execution are critical for the thesis.
1 · Reply
BioRich
BioRich Feb. 3 at 7:45 PM
$ALT Love Guggenheim tying $SGMT to $MDGL. I love that combination. #27Dresses
2 · Reply
Latest News on MDGL
Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra

May 6, 2025, 4:20 PM EDT - 9 months ago

Madrigal Pharmaceuticals: An Encouraging Start For Rezdiffra


Madrigal Appoints Jacqualyn A. Fouse, Ph.D.

Mar 11, 2025, 8:00 AM EDT - 11 months ago

Madrigal Appoints Jacqualyn A. Fouse, Ph.D.


SuperGreenToday
SuperGreenToday Feb. 5 at 11:49 PM
$MDGL Share Price: $463.60 Contract Selected: Jul 17, 2026 $460 Calls Buy Zone: $68.77 – $84.95 Target Zone: $109.43 – $133.75 Potential Upside: 50% ROI Time to Expiration: 161 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
forprofit12
forprofit12 Feb. 5 at 9:39 PM
$MDGL caught in the overall market crossfire. Should be fine long term
0 · Reply
JoeB07
JoeB07 Feb. 5 at 8:54 PM
$MDGL walking it down….where they gonna take it!?
0 · Reply
PashaGainz
PashaGainz Feb. 5 at 7:22 PM
$ALT BP should want ALT ASAP and today’s $HIMS news is exactly why. HIMS just came out with a dirt-cheap “Wegovy pill” alternative (compounded semaglutide) and $NVO is already talking legal action.  That’s the headline, but the bigger message is simple: obesity is turning into a price war. Margins get pressured when the market gets crowded and “cheap options” show up. So where do you keep premium economics? MASH. We literally have proof now: the first MASH drug launched with a $47.4k/year list price and even the street was modeling $30K+ pricing with $MDGL  If you’re BP, the asset you want isn’t “me too obesity.” You want the drug that can be best-in-class, Phase 3-ready, with FDA Breakthrough in MASH, plus an arsenal of other indications to stack value. Obesity alone gets commoditized. Obesity + MASH is where the real money stays. $XBI
6 · Reply
Biohub
Biohub Feb. 5 at 1:50 PM
$MDGL quality analysts have target prices significantly higher first a reason. Blockbuster drug that is still ramping up and with no opposition
0 · Reply
maybeme54
maybeme54 Feb. 4 at 10:59 PM
$MDGL tough start to the year here. Need some upcoming guidance and estimates to be killer! I see $700+ still by the end of the year.
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 4 at 8:41 PM
$MDGL this is not the LLY board.
0 · Reply
ReapN
ReapN Feb. 4 at 8:18 PM
$LLY keeps a ’stranglehold on Glp’ acquires $ALT ’Pemvitude’ Superior in Weight loss. Does Phase 3 continue? Lilly lab, huge advancement in GLP technologies. (Theory) Altimmune positioning into Barbaric. see $MDGL Mash, ’Pemvitude’ multiple designations…. it could happen
0 · Reply
ChainCapital
ChainCapital Feb. 4 at 11:06 AM
$MDGL faces binary outcomes for its NASH drug resmetirom; approval and launch execution are critical for the thesis.
1 · Reply
BioRich
BioRich Feb. 3 at 7:45 PM
$ALT Love Guggenheim tying $SGMT to $MDGL. I love that combination. #27Dresses
2 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 3 at 6:53 PM
$NVO Go blow your wad on $MDGL- that you way you can corner the market on F2-F3 and with F4 $AKRO and offer the oral Wegovy as a combo daily for diabetes etc.
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 3 at 6:38 PM
$MDGL they love pushing the lows on days like this.
0 · Reply
forprofit12
forprofit12 Feb. 3 at 4:55 PM
$MDGL no reason for the beat down. Will continue till ER. Hopefully they nail it. Still bullish 750+ by summer
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Whiskeyunderthebed
Whiskeyunderthebed Feb. 3 at 3:43 PM
$MDGL Go get em Bill-Congratulations on the award!
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GOD_AND_COUNTRY
GOD_AND_COUNTRY Feb. 3 at 5:20 AM
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Expharmaguy
Expharmaguy Feb. 2 at 10:43 PM
$MDGL I do not understand the ALTers. MDGL, NVO, and Lilly have a huge head start in the marketplace. ALT's p3 has not even begun enrollment. Analyses of their data shows a large D/C rate. New CEO was at Intercept, and we all know how that went. They pushed a toxic drug! IMO, there are a dedicated (perhaps paid) cabal of ALT pumpers. Opinion. I do not own shares in MDGL or ALT.
1 · Reply
JoeB07
JoeB07 Feb. 2 at 2:57 PM
$MDGL got a ways to go to hit either of the two lower trendlines. Could be flat to lower for a while. Going to be ready to buy if it heads downward....Also, going to start blocking all the ALT weirdos spamming our board.
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GreenEnergy2022
GreenEnergy2022 Feb. 2 at 1:48 PM
$ALT Watch out $LLY $NVO $RHHBY and $MDGL Looks like a best in class GLP1 for obesity/MASH is coming
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BTECHINV
BTECHINV Feb. 1 at 10:15 PM
$ALT Jeffries reiterated $ 28 PT is a conservative, risk-adjusted figure imo (i.e. recognition that drug candidate is still in clinical trial development). Assuming a successful P3 & NDA, the re-rate would be much closer to MDGL territory imo. BP's who could benefit in my view: $SNY - instantly establishes one of the top global GCGR (and GLP-1) drug pipelines in Pharma with Pemvi $GILD - establishes dominance across the Liver steatosis spectrum (i.e. complements world-class PBC and Hepatitis franchises) $MDGL - establishes a world-class next-gen MOA Liver drug portfolio (THR-B, GCGR) $PFE - potential to transform Pemvi into the equivalent of the cardiometabolic disease age Lipitor 2.0 Disclosure: Long Altimmune (Pemvi GCGR) and Sanofi, not medical / investment advice.
2 · Reply
Tfizzle
Tfizzle Feb. 1 at 8:04 PM
1 · Reply
GreenEnergy2022
GreenEnergy2022 Feb. 1 at 7:14 PM
$ALT Jefferies out with PT 28$ 400% !! LFG, tomorrow we rally. Most undervalued GLP1 in the Obesoty/MASH space $LLY $NVO $GPCR $MDGL
3 · Reply
GreenEnergy2022
GreenEnergy2022 Jan. 30 at 6:32 PM
$ALT Barclays 20$ PT a few days ago: "Pemvitudite could be an important player" They also highlight ALT have a benefit of having weight loss in the same molecule, which Madrigal dont have. Ok! So they dont have weight loss, we have, and they trade at 13B mcap. Mind blowing, huge valuation gap $MDGL
1 · Reply