Market Cap 60.43B
Revenue (ttm) 2.25B
Net Income (ttm) -278.16M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 549.33
Profit Margin -12.37%
Debt to Equity Ratio 0.00
Volume 969,000
Avg Vol 1,221,716
Day's Range N/A - N/A
Shares Out 131.08M
Stochastic %K 56%
Beta 0.36
Analysts Strong Sell
Price Target $468.07

Company Profile

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference. It offers ONPATTRO and AMVUTTRA for hereditary transthyretin-mediated amyloidosis; GIVLAARI for acute hepatic porphyria; OXLUMO for primary hyperoxaluria type 1; and Leqvio for hypercholesterolemia. It also develops vutrisiran, which is in phase III clinical trial for transthyretin amyloidosis (ATTR) with cardiomyopathy; Nucresiran that is in phase I clinical trial for ATTR...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 551 8200
Fax: 617 551 8101
Address:
675 West Kendall Street, Henri A. Termeer Square, Cambridge, United States
LiquidThetaLEAPS
LiquidThetaLEAPS Oct. 4 at 9:51 PM
LiquidTheta® LEAPS LIVE Actionable Alert Asset: $ALNY Current Share Price: $456.35 Contracts: $ALNY January 15, 2027 $460 Calls Scale in: $86.56- $105.79 Scale out: $134.65-$173.12 Can Easily Capture: 60% ROI Blended DTE: 469 Days | Join Elites here: https://liquidtheta.com/options
0 · Reply
highnihilism
highnihilism Oct. 3 at 5:18 PM
$ALNY Alnylam Pharmaceuticals Trades: 76 | Total $: 1.05 M | 0.75 × 90-Day Avg $: 1.41 M | Call $: 415.5 K | Put $: 634.6 K | Single-Leg: 86% | Multi-Leg: 14% $MPWR Monolithic Power Systems Trades: 101 | Total $: 590.4 K | 0.33 × 90-Day Avg $: 1.77 M | Call $: 414.9 K | Put $: 175.5 K | Single-Leg: 68% | Multi-Leg: 32% $IOT Samsara Trades: 720 | Total $: 469.2 K | 0.24 × 90-Day Avg $: 1.95 M | Call $: 412.6 K | Put $: 56.6 K | Single-Leg: 87% | Multi-Leg: 13% $BLDR Builders Firstsource Trades: 284 | Total $: 563.1 K | 0.13 × 90-Day Avg $: 4.31 M | Call $: 412.2 K | Put $: 150.8 K | Single-Leg: 65% | Multi-Leg: 35%
0 · Reply
SweepCastApp
SweepCastApp Oct. 3 at 7:51 AM
$ALNY: Unusual Options Activity Alerted CALL flow observed 13x contracts at Strike price of $520 Exp on 01/16/2026 with Premium of $28K and showing BEARISH Sentiment
0 · Reply
AStrokeOfLuck
AStrokeOfLuck Oct. 2 at 7:06 PM
0 · Reply
topstockalerts
topstockalerts Oct. 2 at 3:49 PM
Alnylam Pharmaceuticals has halted a TV advertisement for its cardiac drug Amvuttra after receiving a warning letter from the FDA. The letter, dated September 9, stated that the ad was misleading because it depicted patients engaging in activities such as whale watching and cheering at football games, suggesting that the drug broadly improves quality of life—a claim not supported by clinical evidence. George Tidmarsh, director of the FDA’s Center for Drug Evaluation and Research, noted that the ad implied patients “can be carefree” about their cardiac condition and could experience wide-ranging life improvements that have not been demonstrated. Alnylam maintains that its promotional materials are “truthful, not misleading, and comply with applicable FDA requirements,” but the company has suspended the TV ad while reviewing the agency’s feedback. $ALNY
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Oct. 2 at 6:23 AM
Enter: $ALNY NOV 21 2025 $470 CALLS Buy in Price: $22.46 - $28.90 Take Profit: $32.12 Stop Bleeding: $19.76 ROI Potential: 43% Exit Within: 106 Minutes https://moneygroup.us/alerts
0 · Reply
SweepCastApp
SweepCastApp Oct. 1 at 7:39 PM
$ALNY: Unusual Options Activity Alerted CALL flow observed 10x contracts at Strike price of $360 Exp on 01/16/2026 with Premium of $102K and showing BULLISH Sentiment
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Oct. 1 at 11:26 AM
Enter: $ALNY NOV 21 2025 $460 CALLS Buy in Price: $30.90 - $31.35 Take Profit: $55.80 Stop Bleeding: $27.59 ROI Potential: 78% Exit Within: 199 Minutes https://moneygroup.us/alerts
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Sep. 30 at 11:05 PM
Enter: $ALNY NOV 21 2025 $460 CALLS Buy in Price: $30.00 - $31.35 Take Profit: $51.10 Stop Bleeding: $27.59 ROI Potential: 63% Exit Within: 376 Minutes https://moneygroup.us/alerts
0 · Reply
johnnygogogo
johnnygogogo Sep. 30 at 4:51 PM
$ALNY thank goodness the $450 champagne is safe. Switching to absinthe and opium when it hits $500 @skeezbag
0 · Reply
Latest News on ALNY
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Mar 20, 2025, 5:59 PM EDT - 7 months ago

US FDA approves Alnylam's drug for rare heart condition


LiquidThetaLEAPS
LiquidThetaLEAPS Oct. 4 at 9:51 PM
LiquidTheta® LEAPS LIVE Actionable Alert Asset: $ALNY Current Share Price: $456.35 Contracts: $ALNY January 15, 2027 $460 Calls Scale in: $86.56- $105.79 Scale out: $134.65-$173.12 Can Easily Capture: 60% ROI Blended DTE: 469 Days | Join Elites here: https://liquidtheta.com/options
0 · Reply
highnihilism
highnihilism Oct. 3 at 5:18 PM
$ALNY Alnylam Pharmaceuticals Trades: 76 | Total $: 1.05 M | 0.75 × 90-Day Avg $: 1.41 M | Call $: 415.5 K | Put $: 634.6 K | Single-Leg: 86% | Multi-Leg: 14% $MPWR Monolithic Power Systems Trades: 101 | Total $: 590.4 K | 0.33 × 90-Day Avg $: 1.77 M | Call $: 414.9 K | Put $: 175.5 K | Single-Leg: 68% | Multi-Leg: 32% $IOT Samsara Trades: 720 | Total $: 469.2 K | 0.24 × 90-Day Avg $: 1.95 M | Call $: 412.6 K | Put $: 56.6 K | Single-Leg: 87% | Multi-Leg: 13% $BLDR Builders Firstsource Trades: 284 | Total $: 563.1 K | 0.13 × 90-Day Avg $: 4.31 M | Call $: 412.2 K | Put $: 150.8 K | Single-Leg: 65% | Multi-Leg: 35%
0 · Reply
SweepCastApp
SweepCastApp Oct. 3 at 7:51 AM
$ALNY: Unusual Options Activity Alerted CALL flow observed 13x contracts at Strike price of $520 Exp on 01/16/2026 with Premium of $28K and showing BEARISH Sentiment
0 · Reply
AStrokeOfLuck
AStrokeOfLuck Oct. 2 at 7:06 PM
0 · Reply
topstockalerts
topstockalerts Oct. 2 at 3:49 PM
Alnylam Pharmaceuticals has halted a TV advertisement for its cardiac drug Amvuttra after receiving a warning letter from the FDA. The letter, dated September 9, stated that the ad was misleading because it depicted patients engaging in activities such as whale watching and cheering at football games, suggesting that the drug broadly improves quality of life—a claim not supported by clinical evidence. George Tidmarsh, director of the FDA’s Center for Drug Evaluation and Research, noted that the ad implied patients “can be carefree” about their cardiac condition and could experience wide-ranging life improvements that have not been demonstrated. Alnylam maintains that its promotional materials are “truthful, not misleading, and comply with applicable FDA requirements,” but the company has suspended the TV ad while reviewing the agency’s feedback. $ALNY
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Oct. 2 at 6:23 AM
Enter: $ALNY NOV 21 2025 $470 CALLS Buy in Price: $22.46 - $28.90 Take Profit: $32.12 Stop Bleeding: $19.76 ROI Potential: 43% Exit Within: 106 Minutes https://moneygroup.us/alerts
0 · Reply
SweepCastApp
SweepCastApp Oct. 1 at 7:39 PM
$ALNY: Unusual Options Activity Alerted CALL flow observed 10x contracts at Strike price of $360 Exp on 01/16/2026 with Premium of $102K and showing BULLISH Sentiment
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Oct. 1 at 11:26 AM
Enter: $ALNY NOV 21 2025 $460 CALLS Buy in Price: $30.90 - $31.35 Take Profit: $55.80 Stop Bleeding: $27.59 ROI Potential: 78% Exit Within: 199 Minutes https://moneygroup.us/alerts
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Sep. 30 at 11:05 PM
Enter: $ALNY NOV 21 2025 $460 CALLS Buy in Price: $30.00 - $31.35 Take Profit: $51.10 Stop Bleeding: $27.59 ROI Potential: 63% Exit Within: 376 Minutes https://moneygroup.us/alerts
0 · Reply
johnnygogogo
johnnygogogo Sep. 30 at 4:51 PM
$ALNY thank goodness the $450 champagne is safe. Switching to absinthe and opium when it hits $500 @skeezbag
0 · Reply
BIOTECH_GURU
BIOTECH_GURU Sep. 30 at 4:05 PM
$BBIO $ALNY $PFE I have been slightly off target... i suspect it will eventually run to 75 by end of year.
1 · Reply
LiquidThetaLEAPS
LiquidThetaLEAPS Sep. 30 at 3:48 PM
LiquidTheta® LEAPS LIVE Actionable Alert Asset: $ALNY Current Share Price: $449.85 Contracts: $ALNY January 15, 2027 $450 Calls Scale in: $80.80- $98.75 Scale out: $125.69-$161.60 Can Easily Capture: 60% ROI Blended DTE: 473 Days | Join Elites here: https://liquidtheta.com/options
0 · Reply
Quantumup
Quantumup Sep. 30 at 3:14 PM
Piper Sandler reiterated $BBIO at Overweight-$68 and said: We hosted a fireside chat with the mgmt team of BBIO and here are our main takeaways. $ALNY $PFE Piper Sanler added: The differentiated efficacy profile is helping support the strong launch dynamics for Attruby. For Q3, mgmt expects for Q3 to follow similar trends to Q2 in terms of free-drug and GTN. Additionally, mgmt reiterated they expect to capture 30-40% of the US ATTR-CM market at peak. The launch of Beyonttra (Attruby) in Germany was stronger compared to the US initially due to wide access at approval and has approximately ~47% of new Rx by 6 months in Germany. Lastly, topline data for Ph. 3 trial of encaleret and BBP-418 should come before Thanksgiving. In totality, it seems like a good set up for BBIO shares to outperform into YE.
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Sep. 29 at 10:43 PM
Enter: $ALNY NOV 21 2025 $450 CALLS Buy in Price: $29.30 - $30.77 Take Profit: $41.90 Stop Bleeding: $25.78 ROI Potential: 43% Exit Within: 94 Minutes https://moneygroup.us/alerts
0 · Reply
highnihilism
highnihilism Sep. 29 at 8:58 PM
$ELV: 638 trades, $21.5M vs $33.1M avg (0.65x). Bearish tilt: $3M calls/$18.5M puts. 63% single-leg. $ADSK: 724 trades, $3.6M vs $2.3M avg (1.58x). Bullish skew: $3M calls/$618K puts. 77% single-leg. $CRSP: 2.7K trades, $3.2M vs $3M avg (1.03x). Bullish skew: $3M calls/$200K puts. 85% single-leg. $ALNY: 239 trades, $4.6M vs $1.3M avg (3.41x). Bullish skew: $2.9M calls/$1.6M puts. 50% single-leg.
0 · Reply
highnihilism
highnihilism Sep. 29 at 8:54 PM
$ADSK: 724 trades, $3.6M vs $2.3M avg (1.58x). Bullish skew: $3M calls/$618K puts. 77% single-leg. $CRSP: 2.7K trades, $3.2M vs $3M avg (1.03x). Bullish skew: $3M calls/$200K puts. 85% single-leg. $ALNY: 239 trades, $4.6M vs $1.3M avg (3.41x). Bullish skew: $2.9M calls/$1.6M puts. 50% single-leg. $ADI: 2.7K trades, $3.8M vs $3.3M avg (1.13x). Bullish skew: $3.3M calls/$440K puts. 93% single-leg.
0 · Reply
SweepCastApp
SweepCastApp Sep. 29 at 2:41 PM
$ALNY: Unusual Options Activity Alerted PUT flow observed 3x contracts at Strike price of $500 Exp on 01/15/2027 with Premium of $30K and showing BEARISH Sentiment
0 · Reply
LiquidThetaLEAPS
LiquidThetaLEAPS Sep. 29 at 1:13 AM
LiquidTheta® LEAPS LIVE Actionable Alert Asset: $ALNY Current Share Price: $446.40 Contracts: $ALNY January 15, 2027 $450 Calls Scale in: $80.80- $98.75 Scale out: $125.69-$161.60 Can Easily Capture: 60% ROI Blended DTE: 474 Days | Join Elites here: https://liquidtheta.com
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Sep. 28 at 12:48 PM
Enter: $ALNY NOV 21 2025 $450 CALLS Buy in Price: $29.30 - $31.40 Take Profit: $45.41 Stop Bleeding: $25.78 ROI Potential: 55% Exit Within: 129 Minutes https://moneygroup.us/alerts
0 · Reply
MoneyGroupLLC
MoneyGroupLLC Sep. 27 at 8:49 PM
Enter: $ALNY NOV 21 2025 $450 CALLS Buy in Price: $29.30 - $31.40 Take Profit: $45.41 Stop Bleeding: $25.78 ROI Potential: 55% Exit Within: 129 Minutes https://moneygroup.us/alerts
0 · Reply
LiquidThetaLEAPS
LiquidThetaLEAPS Sep. 27 at 10:14 AM
LiquidTheta® LEAPS LIVE Actionable Alert Asset: $ALNY Current Share Price: $448.74 Contracts: $ALNY January 15, 2027 $450 Calls Scale in: $81.00- $99.00 Scale out: $126.00-$162.00 Can Easily Capture: 60% ROI Blended DTE: 476 Days | Join Elites here: https://liquidtheta.com
0 · Reply
Fingerlickengood
Fingerlickengood Sep. 26 at 7:39 PM
$CDXS $ALNY $RHHBY https://x.com/CMichaelGibson/status/1968762452213985413
0 · Reply