Market Cap 49.00B
Revenue (ttm) 2.25B
Net Income (ttm) -278.16M
EPS (ttm) N/A
PE Ratio 1,731.70
Forward PE 57.41
Profit Margin -12.37%
Debt to Equity Ratio 0.00
Volume 1,250,000
Avg Vol 1,386,172
Day's Range N/A - N/A
Shares Out 132.11M
Stochastic %K 22%
Beta 0.32
Analysts Strong Sell
Price Target $499.73

Company Profile

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference. It offers ONPATTRO and AMVUTTRA for hereditary transthyretin-mediated amyloidosis; GIVLAARI for acute hepatic porphyria; OXLUMO for primary hyperoxaluria type 1; and Leqvio for hypercholesterolemia. It also develops vutrisiran, which is in phase III clinical trial for transthyretin amyloidosis (ATTR) with cardiomyopathy; Nucresiran that is in phase I clinical trial for ATTR...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 551 8200
Fax: 617 551 8101
Address:
675 West Kendall Street, Henri A. Termeer Square, Cambridge, United States
BillionerOfKing
BillionerOfKing Jan. 15 at 12:14 AM
$ALNY Current Stock Price: $366.81 Contracts to trade: $370 ALNY Jan 16 2026 Call Entry: $2.25 Exit: $4.25 ROI: 89% Hold ~22 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
johnnygogogo
johnnygogogo Jan. 14 at 5:37 PM
$ALNY and now another swill of champagne is approx 12 points away from being spit back into the bottle. Obvious chart gap in the $330 area. Convertible debt rollout was the reason the price got so high imo. Then failed indexation attempt with the S&P 500. Sloppy seconds with the Nasdaq 100 (but not a great time to be in the Nasdaq at a low factor). Even their friendship (“payship”) w/ Statnews isn’t helping the current situation. Photo credit to @Pantherfan7979 cc @skeezbag
1 · Reply
wheresdannynow
wheresdannynow Jan. 13 at 9:09 PM
The whole biotech space rose 33.5% in 2025 per IBD, with standouts like $GILD and $ALNY posting big wins
1 · Reply
Davidendz
Davidendz Jan. 13 at 9:01 PM
Biotech sector crushed 2025 with IBD group up 33.5% Big names like $AMGN +25.6%, $GILD +32.9%, and $ALNY +69% leading the charge. This tailwind into 2026 is perfect for DPX platform plays like $BIOV.CSE $BVAXF fresh off strong Jan 8 NMIBC Phase 1 T-cell data.
0 · Reply
VanRamirez937
VanRamirez937 Jan. 13 at 5:51 PM
$ALNY $AEO Mix of growth styles
0 · Reply
Quantumup
Quantumup Jan. 12 at 7:42 PM
TD Cowen reiterated $BBIO Buy; PT 95 $ALNY $PFE $AZN - $IONS NVO Here's what TD Cowen had to say: Attruby Q4 sales of $146MM beat expectations by 9%, leading to an impressive first full year of sales of $362MM. New patient starts surged with an estimated 25% NBRx share, signaling growing market leadership. The late-stage pipeline anchors the next leg of growth, with Phase III wins for LGMD21 and ADH1, while infi's Q1 data could easily support a best-in-class profile — each with $1B+ potential.
0 · Reply
medguy
medguy Jan. 12 at 6:30 PM
Out with small gains $ALNY
0 · Reply
IN0V8
IN0V8 Jan. 12 at 6:16 PM
$ALNY Watch /Buying Opportunity Needham raises target price to $529 from $520
0 · Reply
REDBEAR
REDBEAR Jan. 12 at 5:50 PM
$ALNY technicians, what's a good level to nibble? funnymentalists, what's happening with the company? asking for a friend. thanks.
0 · Reply
subandh
subandh Jan. 12 at 4:55 PM
$ALNY Next support 349 and if that fails 335 ☹️
0 · Reply
Latest News on ALNY
Is Alnylam Entering A Corrective Phase After A Strong Run?

Dec 16, 2025, 7:04 AM EST - 4 weeks ago

Is Alnylam Entering A Corrective Phase After A Strong Run?


What's Going On With Alnylam Stock On Friday?

Nov 28, 2025, 12:42 PM EST - 6 weeks ago

What's Going On With Alnylam Stock On Friday?


UK's drug-cost watchdog recommends Alnylam's heart disease drug

Nov 20, 2025, 7:09 PM EST - 7 weeks ago

UK's drug-cost watchdog recommends Alnylam's heart disease drug


Why Is Alnylam Pharmaceuticals Stock Trading Lower Thursday?

Oct 30, 2025, 2:39 PM EDT - 2 months ago

Why Is Alnylam Pharmaceuticals Stock Trading Lower Thursday?


mRNA Biotechs - Long-Term Value Risks Abound

Aug 28, 2025, 6:20 AM EDT - 4 months ago

mRNA Biotechs - Long-Term Value Risks Abound

BNTX DHR GRAL ILMN IONS MRNA RGEN


Scenic Enters License and Research Agreement with Alnylam

Aug 26, 2025, 5:00 AM EDT - 5 months ago

Scenic Enters License and Research Agreement with Alnylam


Alnylam: Amvuttra Is Just Getting Started

Jul 31, 2025, 3:13 PM EDT - 5 months ago

Alnylam: Amvuttra Is Just Getting Started


BillionerOfKing
BillionerOfKing Jan. 15 at 12:14 AM
$ALNY Current Stock Price: $366.81 Contracts to trade: $370 ALNY Jan 16 2026 Call Entry: $2.25 Exit: $4.25 ROI: 89% Hold ~22 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
johnnygogogo
johnnygogogo Jan. 14 at 5:37 PM
$ALNY and now another swill of champagne is approx 12 points away from being spit back into the bottle. Obvious chart gap in the $330 area. Convertible debt rollout was the reason the price got so high imo. Then failed indexation attempt with the S&P 500. Sloppy seconds with the Nasdaq 100 (but not a great time to be in the Nasdaq at a low factor). Even their friendship (“payship”) w/ Statnews isn’t helping the current situation. Photo credit to @Pantherfan7979 cc @skeezbag
1 · Reply
wheresdannynow
wheresdannynow Jan. 13 at 9:09 PM
The whole biotech space rose 33.5% in 2025 per IBD, with standouts like $GILD and $ALNY posting big wins
1 · Reply
Davidendz
Davidendz Jan. 13 at 9:01 PM
Biotech sector crushed 2025 with IBD group up 33.5% Big names like $AMGN +25.6%, $GILD +32.9%, and $ALNY +69% leading the charge. This tailwind into 2026 is perfect for DPX platform plays like $BIOV.CSE $BVAXF fresh off strong Jan 8 NMIBC Phase 1 T-cell data.
0 · Reply
VanRamirez937
VanRamirez937 Jan. 13 at 5:51 PM
$ALNY $AEO Mix of growth styles
0 · Reply
Quantumup
Quantumup Jan. 12 at 7:42 PM
TD Cowen reiterated $BBIO Buy; PT 95 $ALNY $PFE $AZN - $IONS NVO Here's what TD Cowen had to say: Attruby Q4 sales of $146MM beat expectations by 9%, leading to an impressive first full year of sales of $362MM. New patient starts surged with an estimated 25% NBRx share, signaling growing market leadership. The late-stage pipeline anchors the next leg of growth, with Phase III wins for LGMD21 and ADH1, while infi's Q1 data could easily support a best-in-class profile — each with $1B+ potential.
0 · Reply
medguy
medguy Jan. 12 at 6:30 PM
Out with small gains $ALNY
0 · Reply
IN0V8
IN0V8 Jan. 12 at 6:16 PM
$ALNY Watch /Buying Opportunity Needham raises target price to $529 from $520
0 · Reply
REDBEAR
REDBEAR Jan. 12 at 5:50 PM
$ALNY technicians, what's a good level to nibble? funnymentalists, what's happening with the company? asking for a friend. thanks.
0 · Reply
subandh
subandh Jan. 12 at 4:55 PM
$ALNY Next support 349 and if that fails 335 ☹️
0 · Reply
subandh
subandh Jan. 12 at 4:46 PM
$ALNY https://www.investors.com/news/technology/alnylam-preannouncement-biotech-companies-jpm/?src=A00220
0 · Reply
OptionRunners
OptionRunners Jan. 12 at 4:22 PM
$ALNY bear seagulls still in the OI from September. Now trading at about $65 .. opened for 0 cost. Max profit is at $360 by expiration ($90). Don't think the market liked the 'trust me bro' approach
0 · Reply
Arcides
Arcides Jan. 12 at 3:44 PM
$SMMT $ALNY BIos are pupu today.
0 · Reply
Jschwarma
Jschwarma Jan. 12 at 2:45 PM
$ARWR would be nice to take some of the market cap that $ALNY is losing today
1 · Reply
CDMO
CDMO Jan. 12 at 2:35 PM
$ALNY down massively...whats uppppp
1 · Reply
Fingerlickengood
Fingerlickengood Jan. 8 at 8:40 PM
$CDXS $BCHME Look closely at the last slide and what they’ve scaled up! vutrisiran aka amvuttra owned by $ALNY https://www.amvuttra.com/attr-cm?utm_source=google&utm_medium=cpc&utm_campaign=Alnylam+%7C+Amvuttra+Patient+%7CBranded/Generic+terms%7C+AMVUTTRA+ONLY_NO+SEARCH+PARTNER+%7C+Phase+2+%7C+Google+2025&utm_content=Branded/Generic+terms+-+Phrase&utm_term=amvuttra&gclsrc=aw.ds&gad_source=1&gad_campaignid=23005652621&gbraid=0AAAAAorktACCVjsRMsgBL8m7BAdpsz5Jt&gclid=Cj0KCQiAyP3KBhD9ARIsAAJLnnbBZ9332J-DqlgHjVku4X2NRMwA17keIN0WgZfG7mKsZQYJxqgx4UsaAskKEALw_wcB
1 · Reply
Fingerlickengood
Fingerlickengood Jan. 8 at 7:16 PM
$CDXS Why aren't these companies partnering with $ALNY and evaluating their platform? Does the market believe $CDXS is too small to succeed? https://www.biospace.com/press-releases/alnylam-to-invest-250-million-to-add-enzymatic-ligation-platform-to-u-s-manufacturing-facility-to-meet-growing-global-demand-for-rnai-therapeutics
2 · Reply
skeezbag
skeezbag Jan. 8 at 1:52 PM
$ARWR 78% short volume yesterday. Short the common the day any converts are announced by the hedgies. It doesn't last though. See $IONS $ALNY Overall 0% interest on converts in smid bio means arrowhead has arrived and investors want the common upside
1 · Reply
Dark_Horse_Investments
Dark_Horse_Investments Jan. 7 at 7:59 PM
$ARWR The good ol' Anzalone rug pull. Guess the company needs the capital and this is the time to raise cash. Unfortunately, our analysis points that this company has a bloated payroll &out of control opex - for several years. Doesn't really look like they're financial disciplinarians ... Consider the following, 1) treasury stock from returned equity from SRPT, ~$80 m @ current levels - would not be surprised if this is sold by the next sec filing ; 2) milestones coming from sanofi $SNI, plozasiran approval in china ; 3) latest SRPT milestones (well lets see if they pay up - they need the scientific asset for survival). Hopefully with the notes, they retire more expensive debt. Though happy about the good return, never have placed high concentration confidence on the anzalone's... this could be the next $ALNY but it seems like this is not the last equity raise ...
1 · Reply
johnnygogogo
johnnygogogo Jan. 6 at 3:20 PM
$ALNY they need a weight loss drug after all the champagn-nya and ca-we-ar @skeezbag
0 · Reply
Quantumup
Quantumup Jan. 6 at 11:23 AM
Morgan Stanley🏁 $BBIO Overweight/$96 and said: Initiating coverage of BridgeBio Pharma (BBIO) with an Overweight rating and a $96 price target, implying 20%+ upside from current levels. $ALNY $PFE $AZN $BAYRY BMRN ASND MS added: BBIO is well- positioned as a leading rare disease company with a diversified late-stage pipeline and a commercial-stage asset (Attruby/acoramidis) in ATTR-CM, a serious heart condition that can lead to heart failure. The company is evolving into a multi-product rare disease franchise, supported by recent Phase 3 wins and upcoming regulatory catalysts. Profitability inflexion point - another "SMID to Big" candidate: We see BBIO achieving positive net income and free cash flow in 2027E. Given our forecast top-line 2025-2030 CAGR of +39% with relatively more modest growth in opex, our implied BBIO P/E in 2030E is a lowly 5.7x (for reference, MS US Large Cap Biopharma average 2025E P/E stands at ~14x) suggesting a compelling long-term opportunity for investors.
1 · Reply
WallStreetBuyDip
WallStreetBuyDip Jan. 2 at 1:34 AM
$ALNY Massive price range from $224.32 to $491.22. Recent volume has been below average, with the latest at 768,900 shares traded. Smart money might wait for a lower H% before considering an entry.
0 · Reply