Market Cap 40.38B
Revenue (ttm) 2.25B
Net Income (ttm) -278.16M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -12.37%
Debt to Equity Ratio 0.00
Volume 1,000,000
Avg Vol 947,080
Day's Range N/A - N/A
Shares Out 130.39M
Stochastic %K 80%
Beta 0.22
Analysts Strong Sell
Price Target $325.23

Company Profile

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference. It offers ONPATTRO and AMVUTTRA for hereditary transthyretin-mediated amyloidosis; GIVLAARI for acute hepatic porphyria; OXLUMO for primary hyperoxaluria type 1; and Leqvio for hypercholesterolemia. It also develops vutrisiran, which is in phase III clinical trial for transthyretin amyloidosis (ATTR) with cardiomyopathy; Nucresiran that is in phase I clinical trial for ATTR...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 551 8200
Fax: 617 551 8101
Address:
675 West Kendall Street, Henri A. Termeer Square, Cambridge, United States
Wrangler4
Wrangler4 Jun. 24 at 7:02 PM
$AGIO $ALNY ….when ya know , ya know !!
0 · Reply
Jadek6
Jadek6 Jun. 24 at 6:59 PM
$ALNY $CADL …looks as though shareholders of CADL are bag holders for a less credible CEO in Tak Than a big pharma Gal ..Yvonne Greenstreet ( ex Pfizer big wheel , NOT GLAXO HACK ) and never reverts to social media for minion support
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Jadek6
Jadek6 Jun. 24 at 6:52 PM
$ALNY $AGIO clearly ..ceo is Yvonne Greenstreet Big Pharma gal from Pfizer and John Maraganore believes in her She is no fcuking , Fouse or Brian Useless Goff over at that LAME $AGIOS
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CDMO
CDMO Jun. 18 at 1:45 PM
$ALNY ATH bitcheees
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roger120
roger120 Jun. 17 at 12:23 PM
$VERV $BBIO $ALNY $VKTX $NVO i hope someone was able to do some DD based after this post and made some 🤑
3 · Reply
buymoremakemore
buymoremakemore Jun. 13 at 7:46 PM
$ALNY Bought 150 shares long @ $305.
0 · Reply
NancyPelosi____insider
NancyPelosi____insider Jun. 13 at 12:59 PM
0 · Reply
JarvisFlow
JarvisFlow Jun. 12 at 1:39 PM
JP Morgan has updated their rating for Alnylam Pharmaceuticals ( $ALNY ) to Overweight with a price target of 338.
1 · Reply
getitarian
getitarian Jun. 12 at 1:24 PM
Is it too far of a stretch for $ABUS to one day reach a similar valuation to $ALNY if there are recurring revenues on LNP and/or HBV royalties?
3 · Reply
TICKERTUTOR
TICKERTUTOR Jun. 10 at 3:53 PM
$ALNY June 310C
0 · Reply
Latest News on ALNY
Alnylam Pharmaceuticals Names Garg R&D Chief

Jun 18, 2025, 12:04 PM EDT - 6 days ago

Alnylam Pharmaceuticals Names Garg R&D Chief


Alnylam Issues 2024 Corporate Responsibility Report

May 20, 2025, 9:00 AM EDT - 5 weeks ago

Alnylam Issues 2024 Corporate Responsibility Report


Alnylam Pharmaceuticals Ready To Go With Its Next Blockbuster

Mar 21, 2025, 5:37 PM EDT - 3 months ago

Alnylam Pharmaceuticals Ready To Go With Its Next Blockbuster


Alnylam shares rise on expanded heart drug approval

Mar 21, 2025, 7:34 AM EDT - 3 months ago

Alnylam shares rise on expanded heart drug approval


US FDA approves Alnylam's drug for rare heart condition

Mar 20, 2025, 5:59 PM EDT - 3 months ago

US FDA approves Alnylam's drug for rare heart condition


Alnylam to Webcast Presentation at Stifel 2025 Virtual CNS Forum

Mar 11, 2025, 8:00 AM EDT - 3 months ago

Alnylam to Webcast Presentation at Stifel 2025 Virtual CNS Forum


Alnylam: Waiting For Regulatory Updates In March

Feb 13, 2025, 5:01 PM EST - 4 months ago

Alnylam: Waiting For Regulatory Updates In March


Alnylam to Webcast TTR Investor Day

Sep 26, 2024, 8:00 AM EDT - 9 months ago

Alnylam to Webcast TTR Investor Day


Alnylam: HELIOS-B Success Priced In Already

Aug 30, 2024, 12:29 PM EDT - 10 months ago

Alnylam: HELIOS-B Success Priced In Already


Wrangler4
Wrangler4 Jun. 24 at 7:02 PM
$AGIO $ALNY ….when ya know , ya know !!
0 · Reply
Jadek6
Jadek6 Jun. 24 at 6:59 PM
$ALNY $CADL …looks as though shareholders of CADL are bag holders for a less credible CEO in Tak Than a big pharma Gal ..Yvonne Greenstreet ( ex Pfizer big wheel , NOT GLAXO HACK ) and never reverts to social media for minion support
0 · Reply
Jadek6
Jadek6 Jun. 24 at 6:52 PM
$ALNY $AGIO clearly ..ceo is Yvonne Greenstreet Big Pharma gal from Pfizer and John Maraganore believes in her She is no fcuking , Fouse or Brian Useless Goff over at that LAME $AGIOS
0 · Reply
CDMO
CDMO Jun. 18 at 1:45 PM
$ALNY ATH bitcheees
0 · Reply
roger120
roger120 Jun. 17 at 12:23 PM
$VERV $BBIO $ALNY $VKTX $NVO i hope someone was able to do some DD based after this post and made some 🤑
3 · Reply
buymoremakemore
buymoremakemore Jun. 13 at 7:46 PM
$ALNY Bought 150 shares long @ $305.
0 · Reply
NancyPelosi____insider
NancyPelosi____insider Jun. 13 at 12:59 PM
0 · Reply
JarvisFlow
JarvisFlow Jun. 12 at 1:39 PM
JP Morgan has updated their rating for Alnylam Pharmaceuticals ( $ALNY ) to Overweight with a price target of 338.
1 · Reply
getitarian
getitarian Jun. 12 at 1:24 PM
Is it too far of a stretch for $ABUS to one day reach a similar valuation to $ALNY if there are recurring revenues on LNP and/or HBV royalties?
3 · Reply
TICKERTUTOR
TICKERTUTOR Jun. 10 at 3:53 PM
$ALNY June 310C
0 · Reply
TICKERTUTOR
TICKERTUTOR Jun. 10 at 2:57 PM
$ALNY CEO's last name is GREENstreet. Think this one has the potential to pull off a VRTX-like run.
0 · Reply
ZacksResearch
ZacksResearch Jun. 10 at 2:05 PM
$ALNY's Amvuttra secures EC approval for cardiomyopathy treatment! 🚀 Amvuttra now treats wild-type or hereditary transthyretin amyloidosis in cardiomyopathy patients, backed by HELIOS-B study results showing significant reductions in mortality and cardiovascular events. With a YTD stock rally of 29.1%, this approval could boost future sales. 📈 Full analysis here 👉 https://www.zacks.com/commentary/2492254/alnylam-wins-ec-nod-for-label-expansion-of-amvuttra-for-attr-cm?cid=sm-stocktwits-2-2492254-body&ADID=SYND_STOCKTWITS_TWEET_2_2492254_BODY
0 · Reply
ZacksResearch
ZacksResearch Jun. 10 at 12:11 PM
$ALNY just secured a big EU win — here’s why it matters 🎯 Label expansion for Amvuttra makes it the only RNAi therapy approved for ATTR-CM in the region, strengthening its competitive edge. Full details on the approval and what it could mean for growth 👉 https://www.zacks.com/stock/news/2492254/alnylam-wins-ec-nod-for-label-expansion-of-amvuttra-for-attr-cm?cid=sm-stocktwits-2-2492254-teaser&ADID=SYND_STOCKTWITS_TWEET_2_2492254_TEASER
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Quantumup
Quantumup Jun. 9 at 11:17 AM
H.C. Wainwright⬆️the PT on $BBIO to $56 from $53 and reiterated at a Buy to reflect an upward revision of its 2025 and 2026 revenue estimates. $ALNY $PFE $ASND $AZN H.C. Wainwright said in its note to investors:
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DonCorleone77
DonCorleone77 Jun. 9 at 10:12 AM
$ALNY Alnylam receives European Commission approval of AMVUTTRA Alnylam Pharmaceuticals announced that the European Commission has granted approval for the treatment of wild-type or hereditary transthyretin amyloidosis in adult patients with cardiomyopathy as an additional indication for its orphan RNAi therapeutic AMVUTTRA. The approval broadens the indication for AMVUTTRA, which now becomes the first and only RNAi therapeutic approved by the EC for the treatment of the cardiomyopathy manifestations of ATTR amyloidosis and the polyneuropathy manifestations of hereditary transthyretin-mediated amyloidosis in adults.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jun. 9 at 12:19 AM
The attached graph compares $REGN actual FY23, FY24 and FY25-34 analyst consensus revenue estimates to $CELG FY17, FY18 and FY19 - 28 projections prepared by CELG management. REGN is not anticipated to grow like CELG but... Differences in gross margins noted. CELG was acquired for an enterprise value of $90B which was 0.42X its cumulative 10-year projected revenues. With REGN's cash, its enterprise value is roughly $39B which is 0.23X its like 10-year revenue estimates. Yes with REGN's cash, its enterprise value is significantly lower than its market cap. We're curious if any REGN investors believe its stock is a good value under $500/share with its $14B net cash/debt or are there risks of significant declines from here? Next up will be $ALNY versus $SGEN This is not investment advice. $XBI
1 · Reply
Fingerlickengood
Fingerlickengood Jun. 6 at 7:55 PM
$CDXS $BCHMF $NVS $ALNY https://www.pharmacytimes.com/view/nla-2025-inclisiran-with-standard-care-provides-rapid-sustained-lowering-of-ldl-c-in-patients-with-recent-acute-coronary-syndrome
1 · Reply
Quantumup
Quantumup Jun. 6 at 11:48 AM
Piper Sandler reiterated $BBIO Overweight-$63 and said "Encaleret Phase 3 CALIBRATE Readout Offers an Under-The-Radar 2H '25 Catalyst" $ASND $AZN $ALNY $PFE Piper Sandler added, "The Phase 3 topline readout of the CALIBRATE study of $BBIO's calcilytic, encaleret, will be disclosed in the 2H '25 (we think Sept/Oct timeframe). Based on the positive efficacy data presented for the Phase 2b study of encaleret in moderate-to-severe patients with ADH1, we think those data are supportive of a positive outcome in CALIBRATE in 67 patients with ADH1. We estimate risk-adjusted US/EU peak sales of $389M (we have a 40% discount) for ADH1, and these estimates represents about ~9% of total product revenues. Furthermore, there are readthroughs of ADH1 to a broader chronic hypoparathyroidism indication from a biochemical and b/g med viewpoint, and as a result, there is possible derisking with CALIBRATE to the hypoparathyroidism opportunity."
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Wrangler4
Wrangler4 Jun. 5 at 12:34 AM
$CADL ..I do ..but not in a TAK pos company that only he touts , like Trump ..he touts the tariff deals..and guess what Neither TAK OR TRUMP HAVE DEALS…the are both losers I own $ALNY , JOHN M. Is a whole different class than TAK. KNOW IT..SEEN IT ….you are delusional ! @ilikemoney247 Not assume my grasp of good companies…I’ve been around the block with DELL, COMPAQ APPLE MSFT TAK IS JUNK
1 · Reply
xersdave
xersdave Jun. 1 at 7:31 PM
$XERS $ATYR $XERS - A pretty safe investment into a slow but steady growing company. Their largest, TAM drug in their pipeline is LEVO, which could be their biggest asset yet, once their P3 trial starts in 2026 and probably ends in 2028, and after FDA approval. I estimate with steady growth, their SP can double to $10 by 2027-2028. Then, if approved, LEVO hits. My goal for this stock is to sell at $12-$20 depending on the timeline, growth results and/or BO. $ATYR - A high risk, high reward stock founded by Paul Schimmel. Schimmel has founded over 11 companies I believe, several whom have been BO and some which are still listed on the market, such as $ALNY, which holds a market cap of 39.7B and a SP of $306. Major P3 catalyst data readout set for Q3 2025. If results are good, analysts project a 4x-10x SP. Not to mention this stock is 70% institutionally owned, a rare feat for a tiny small cap biotech with no products on the market. Just my opinions. Do your own DD. Good luck!
2 · Reply
johnnygogogo
johnnygogogo May. 31 at 1:24 AM
$ALNY almost a $10M sale from the CEO today but who cares, right? Seen here at the KOL dinner, “in Boston”
1 · Reply
kellysmith1
kellysmith1 May. 30 at 7:34 PM
$ALNY $BBIO $NTLA $PFE who cares
1 · Reply