Market Cap 117.32B
Revenue (ttm) 11.02B
Net Income (ttm) -535.60M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 29.94
Profit Margin -4.86%
Debt to Equity Ratio 0.00
Volume 1,857,300
Avg Vol 1,261,596
Day's Range N/A - N/A
Shares Out 256.80M
Stochastic %K 33%
Beta 0.41
Analysts Sell
Price Target $514.73

Company Profile

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 341 6100
Address:
50 Northern Avenue, Boston, United States
ChessGM
ChessGM Aug. 1 at 10:52 PM
Heads up alert! Only three days until Upcoming earnings on Monday, 8/4/2025 for $VRTX Bullish (7.9) Vertex Pharmaceuticals (VRTX) has demonstrated strong financial performance and strategic advancements which have positively influenced its stock outlook. The company's recent earnings report suggests robust triple-digit earnings growth, buoyed by surging sales of Trikafta, and strong performance in its cystic fibrosis franchise. This is further supported by the EU and NHS England's approval of ALYFTREK, a next-generation CFTR modulator, enhancing Vertex's market reach and potential revenue streams. Vertex's innovative pipeline, including advancements in gene therapy and non-opioid pain relief, positions it well against industry peers. The stock trades at a P/E ratio that reflects its growth potential, supported by consistent EPS growth and strategic market expansion. Compared to industry peers, Vertex maintains a competitive edge with its robust pipeline and approved therapies, which could result in sustained revenue growth and shareholder value. Upcoming Earnings Report: Vertex Pharmaceuticals is slated to release its second-quarter 2025 financial results on August 4th. Analyst consensus projects significant earnings growth, driven by the continued success of its cystic fibrosis treatments and promising pipeline developments. Historically, Vertex has demonstrated a strong track record of meeting or exceeding earnings expectations, which could positively impact its stock price if trends continue. Wall Street anticipates a focus on the performance of new product launches, such as ALYFTREK, and updates on developmental milestones for its other pipeline candidates. A positive earnings surprise could bolster investor confidence and drive further stock appreciation. Sector Performance: Vertex Pharmaceuticals operates within the biotechnology sector, which has experienced mixed performance recently. While some companies have faced challenges due to regulatory hurdles and competitive pressures, others, like Vertex, have thrived due to successful drug approvals and innovative pipelines. The sector has benefited from increased investment in healthcare innovation, particularly in areas like gene therapy and personalized medicine, which aligns well with Vertex's strategic focus. Overall, the biotechnology sector remains a dynamic and potentially lucrative space for investors, with companies like Vertex leading the charge in therapeutic advancement and market expansion. - Funds were net sellers of $VRTX during the previous reporting quarter. - Funds with large holdings in $VRTX include: - Edgewood Management LLC, MV: $1,282MM. Fund Rank: 87% www.edgewood.com - Adage Capital P, MV: $237MM. Fund Rank: 86% www.adagecapital.com - OrbiMed Advisors LLC, MV: $78MM. Fund Rank: 55% www.orbimed.com - Canada Pension , MV: $75MM. Fund Rank: 76% - Baillie Gifford & Co Ltd, MV: $65MM. Fund Rank: 90% www.bailliegifford.com - Last 10 days performance: -3% - Last 30 days performance: 0% - Last 90 days performance: -9% Some of the latest news articles: - Title: KBRA Assigns Preliminary Ratings to VRTX 2025-HQ Publication Date: 8/1/2025 5:14:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/kbra-assigns-preliminary-ratings-vrtx-171400086.html?.tsrc=rss - Title: 2 Top Stocks I Wouldn't Hesitate to Invest $1,000 in Right Now Publication Date: 8/1/2025 10:30:00 AM, Source: yahoo URL: https://www.fool.com/investing/2025/08/01/2-top-stocks-i-wouldnt-hesitate-to-invest-1000-in/?.tsrc=rss - Title: Stocks Erase Early Gains as Chip Makers and Big Pharma Retreat Publication Date: 7/31/2025 8:32:27 PM, Source: yahoo URL: https://www.barchart.com/story/news/33792613/stocks-erase-early-gains-as-chip-makers-and-big-pharma-retreat?.tsrc=rss - Title: Stay Ahead of the Game With Vertex (VRTX) Q2 Earnings: Wall Street's Insights on Key Metrics Publication Date: 7/30/2025 1:15:05 PM, Source: yahoo URL: https://finance.yahoo.com/news/stay-ahead-game-vertex-vrtx-131505289.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal.
0 · Reply
Prester_John
Prester_John Aug. 1 at 9:32 PM
$VRTX Just the Facts ( you're Fired) https://www.trefis.com/stock/vrtx/articles/571429/how-to-trade-vertex-pharmaceuticals-stock-ahead-of-its-upcoming-earnings/2025-08-01
0 · Reply
profit_guru
profit_guru Aug. 1 at 6:59 PM
$ABBV - more analysts price target raises next week…earnings from $VRTX and $LLY will rally $ABBV to new 52 wk highs next week…near term 220…imo
0 · Reply
scientificway
scientificway Jul. 31 at 10:44 PM
$VRTX MDXG, guidance up
0 · Reply
kamenrider888
kamenrider888 Jul. 31 at 3:55 PM
$VRTX below $500...as predicted.. where are the bulls now?😂 And it's still overpriced
0 · Reply
SparkyReturns
SparkyReturns Jul. 31 at 2:37 PM
$GILD So, just FYI. $PFE $VRTX $SNY
0 · Reply
NVDAMillionaire
NVDAMillionaire Jul. 30 at 7:45 PM
$VRTX Outstanding article that hits the mark on VRTX's current state. So if you want to refresh your VRTX insights or learn about VRTX from scratch, this is a must read. https://beyondspx.com/article/vertex-pharmaceuticals-launching-a-new-era-of-growth-and-diversification-vrtx
0 · Reply
Quantumup
Quantumup Jul. 30 at 12:10 PM
H.C. Wainwright yesterday⬆️ $FULC to Buy-$12 from Neutral-$4. $PFE $VRTX $QURE SGMO $AGIO CRSP BLUE - CG H.C. Wainwright said, "Today's 12mg dataset from Fulcrum's PIONEER Phase 1b trial builds meaningfully on prior mechanistic and early clinical observations, offering a tangible glimpse into the translational potential of HbF induction in sickle cell disease (SCD). We view the absolute increase in fetal hemoglobin (HbF), combined with improvements in key hematologic and hemolytic parameters, as validation of pociredir's ability to recapitulate the protective biology observed in hereditary persistence of fetal hemoglobin (HPFH). This matters clinically because patients with HPFH exhibit far fewer vaso-occlusive complications despite possessing the same ß-globin mutation. H.C. Wainwright additionally said:
0 · Reply
svertical1
svertical1 Jul. 30 at 4:52 AM
$VRTX Great news for small and large biotech! We need someone who understands the need for speed in innovation. We’re up against China. Opioid crisis remains an issue with >50k deaths per year. A biotech could ‘cure’ paralysis, but the OLD FDA would require a decade of testing. It took 60 months of CASGEVY data….how many died before they had a chance for functional SCD cure.
0 · Reply
akinyo
akinyo Jul. 29 at 4:12 PM
$VRTX boom!! Big move today 💥
0 · Reply
Latest News on VRTX
How Will VRTX Stock React To Its Upcoming Earnings?

Aug 2, 2025, 12:20 AM EDT - 17 hours ago

How Will VRTX Stock React To Its Upcoming Earnings?


Vertex to Participate in Upcoming Investor Conferences

May 15, 2025, 4:05 PM EDT - 2 months ago

Vertex to Participate in Upcoming Investor Conferences


Why Did Vertex Pharmaceuticals Stock Fall On Tuesday?

May 6, 2025, 4:28 PM EDT - 3 months ago

Why Did Vertex Pharmaceuticals Stock Fall On Tuesday?


Vertex Reports First Quarter 2025 Financial Results

May 5, 2025, 4:01 PM EDT - 3 months ago

Vertex Reports First Quarter 2025 Financial Results


GreensKeeper Q1 2025 Portfolio Update

Apr 10, 2025, 8:55 AM EDT - 4 months ago

GreensKeeper Q1 2025 Portfolio Update

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Vertex Announces Program Updates for Type 1 Diabetes Portfolio

Mar 28, 2025, 4:05 PM EDT - 4 months ago

Vertex Announces Program Updates for Type 1 Diabetes Portfolio


Final Trades: Vertex Pharma, Netflix and the IYF

Mar 27, 2025, 5:14 PM EDT - 4 months ago

Final Trades: Vertex Pharma, Netflix and the IYF

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Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals

Mar 24, 2025, 1:19 PM EDT - 4 months ago

Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals


ChessGM
ChessGM Aug. 1 at 10:52 PM
Heads up alert! Only three days until Upcoming earnings on Monday, 8/4/2025 for $VRTX Bullish (7.9) Vertex Pharmaceuticals (VRTX) has demonstrated strong financial performance and strategic advancements which have positively influenced its stock outlook. The company's recent earnings report suggests robust triple-digit earnings growth, buoyed by surging sales of Trikafta, and strong performance in its cystic fibrosis franchise. This is further supported by the EU and NHS England's approval of ALYFTREK, a next-generation CFTR modulator, enhancing Vertex's market reach and potential revenue streams. Vertex's innovative pipeline, including advancements in gene therapy and non-opioid pain relief, positions it well against industry peers. The stock trades at a P/E ratio that reflects its growth potential, supported by consistent EPS growth and strategic market expansion. Compared to industry peers, Vertex maintains a competitive edge with its robust pipeline and approved therapies, which could result in sustained revenue growth and shareholder value. Upcoming Earnings Report: Vertex Pharmaceuticals is slated to release its second-quarter 2025 financial results on August 4th. Analyst consensus projects significant earnings growth, driven by the continued success of its cystic fibrosis treatments and promising pipeline developments. Historically, Vertex has demonstrated a strong track record of meeting or exceeding earnings expectations, which could positively impact its stock price if trends continue. Wall Street anticipates a focus on the performance of new product launches, such as ALYFTREK, and updates on developmental milestones for its other pipeline candidates. A positive earnings surprise could bolster investor confidence and drive further stock appreciation. Sector Performance: Vertex Pharmaceuticals operates within the biotechnology sector, which has experienced mixed performance recently. While some companies have faced challenges due to regulatory hurdles and competitive pressures, others, like Vertex, have thrived due to successful drug approvals and innovative pipelines. The sector has benefited from increased investment in healthcare innovation, particularly in areas like gene therapy and personalized medicine, which aligns well with Vertex's strategic focus. Overall, the biotechnology sector remains a dynamic and potentially lucrative space for investors, with companies like Vertex leading the charge in therapeutic advancement and market expansion. - Funds were net sellers of $VRTX during the previous reporting quarter. - Funds with large holdings in $VRTX include: - Edgewood Management LLC, MV: $1,282MM. Fund Rank: 87% www.edgewood.com - Adage Capital P, MV: $237MM. Fund Rank: 86% www.adagecapital.com - OrbiMed Advisors LLC, MV: $78MM. Fund Rank: 55% www.orbimed.com - Canada Pension , MV: $75MM. Fund Rank: 76% - Baillie Gifford & Co Ltd, MV: $65MM. Fund Rank: 90% www.bailliegifford.com - Last 10 days performance: -3% - Last 30 days performance: 0% - Last 90 days performance: -9% Some of the latest news articles: - Title: KBRA Assigns Preliminary Ratings to VRTX 2025-HQ Publication Date: 8/1/2025 5:14:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/kbra-assigns-preliminary-ratings-vrtx-171400086.html?.tsrc=rss - Title: 2 Top Stocks I Wouldn't Hesitate to Invest $1,000 in Right Now Publication Date: 8/1/2025 10:30:00 AM, Source: yahoo URL: https://www.fool.com/investing/2025/08/01/2-top-stocks-i-wouldnt-hesitate-to-invest-1000-in/?.tsrc=rss - Title: Stocks Erase Early Gains as Chip Makers and Big Pharma Retreat Publication Date: 7/31/2025 8:32:27 PM, Source: yahoo URL: https://www.barchart.com/story/news/33792613/stocks-erase-early-gains-as-chip-makers-and-big-pharma-retreat?.tsrc=rss - Title: Stay Ahead of the Game With Vertex (VRTX) Q2 Earnings: Wall Street's Insights on Key Metrics Publication Date: 7/30/2025 1:15:05 PM, Source: yahoo URL: https://finance.yahoo.com/news/stay-ahead-game-vertex-vrtx-131505289.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal.
0 · Reply
Prester_John
Prester_John Aug. 1 at 9:32 PM
$VRTX Just the Facts ( you're Fired) https://www.trefis.com/stock/vrtx/articles/571429/how-to-trade-vertex-pharmaceuticals-stock-ahead-of-its-upcoming-earnings/2025-08-01
0 · Reply
profit_guru
profit_guru Aug. 1 at 6:59 PM
$ABBV - more analysts price target raises next week…earnings from $VRTX and $LLY will rally $ABBV to new 52 wk highs next week…near term 220…imo
0 · Reply
scientificway
scientificway Jul. 31 at 10:44 PM
$VRTX MDXG, guidance up
0 · Reply
kamenrider888
kamenrider888 Jul. 31 at 3:55 PM
$VRTX below $500...as predicted.. where are the bulls now?😂 And it's still overpriced
0 · Reply
SparkyReturns
SparkyReturns Jul. 31 at 2:37 PM
$GILD So, just FYI. $PFE $VRTX $SNY
0 · Reply
NVDAMillionaire
NVDAMillionaire Jul. 30 at 7:45 PM
$VRTX Outstanding article that hits the mark on VRTX's current state. So if you want to refresh your VRTX insights or learn about VRTX from scratch, this is a must read. https://beyondspx.com/article/vertex-pharmaceuticals-launching-a-new-era-of-growth-and-diversification-vrtx
0 · Reply
Quantumup
Quantumup Jul. 30 at 12:10 PM
H.C. Wainwright yesterday⬆️ $FULC to Buy-$12 from Neutral-$4. $PFE $VRTX $QURE SGMO $AGIO CRSP BLUE - CG H.C. Wainwright said, "Today's 12mg dataset from Fulcrum's PIONEER Phase 1b trial builds meaningfully on prior mechanistic and early clinical observations, offering a tangible glimpse into the translational potential of HbF induction in sickle cell disease (SCD). We view the absolute increase in fetal hemoglobin (HbF), combined with improvements in key hematologic and hemolytic parameters, as validation of pociredir's ability to recapitulate the protective biology observed in hereditary persistence of fetal hemoglobin (HPFH). This matters clinically because patients with HPFH exhibit far fewer vaso-occlusive complications despite possessing the same ß-globin mutation. H.C. Wainwright additionally said:
0 · Reply
svertical1
svertical1 Jul. 30 at 4:52 AM
$VRTX Great news for small and large biotech! We need someone who understands the need for speed in innovation. We’re up against China. Opioid crisis remains an issue with >50k deaths per year. A biotech could ‘cure’ paralysis, but the OLD FDA would require a decade of testing. It took 60 months of CASGEVY data….how many died before they had a chance for functional SCD cure.
0 · Reply
akinyo
akinyo Jul. 29 at 4:12 PM
$VRTX boom!! Big move today 💥
0 · Reply
ZacksResearch
ZacksResearch Jul. 29 at 3:40 PM
$VRTX gearing up for a Q2 surprise? Trikafta sales are surging, and eyes are on Casgevy progress plus the Alyftrek and Journavx launches. Full earnings preview here 👉 https://www.zacks.com/stock/news/2633420/vertex-gears-up-to-report-q2-earnings-is-a-beat-in-the-cards?cid=sm-stocktwits-2-2633420-teaser-4481&ADID=SYND_STOCKTWITS_TWEET_2_2633420_TEASER_4481
0 · Reply
ZacksResearch
ZacksResearch Jul. 29 at 2:27 PM
$VRTX set to beat Q2 earnings estimates? 🚀 🔹 Zacks Consensus Estimate: $4.24 EPS, $2.89B revenue 🔹 Strong Trikafta/Kaftrio demand in the U.S. 🔹 Earnings ESP of +1.82% & Zacks Rank #3 = potential earnings beat Full earnings preview here 👉 https://www.zacks.com/stock/news/2633420/vertex-gears-up-to-report-q2-earnings-is-a-beat-in-the-cards?cid=sm-stocktwits-2-2633420-body-4447&ADID=SYND_STOCKTWITS_TWEET_2_2633420_BODY_4447
0 · Reply
ThatsNoMoon
ThatsNoMoon Jul. 29 at 11:39 AM
$APLS This approval de-risks APLS as a buyout candidate, esp for a bigger co looking to bolster their nephrology program, *ahem, $VRTX* Even better if said larger co was lead by a trained nephrologist, *ahem, Reshma* 😉
0 · Reply
JerryMalone32
JerryMalone32 Jul. 29 at 5:16 AM
$SANA Question for those much, much smarter than me. Is the scaling problem simply a function of a lot of capital and a lot of time. Or are there scientific challenges, too? What, specifically, would $VRTX lend to the task that could not be done by $SANA, itself?
1 · Reply
DayTradeAISignals
DayTradeAISignals Jul. 28 at 2:51 AM
Following are our top 3 day trades of this week : $NOW 2025-07-21 14:20:04 Buy $961.62| Profit $966.24 $VRTX 025-07-23 11:09:31 Buy $475.9|Profit $478.72 $TSLA 2025-07-25 10:34:40 BUY $313.07|Profit $315.93 #StockTrading #TradingSignals #DayTradeSignals
0 · Reply
muldoon92
muldoon92 Jul. 27 at 10:17 PM
$VRTX has reclaimed the 200-day MA twice now recently, included a pretty little backtest with a hammer close Friday. I don't think we are going below that again unless brought on by a news triggered event (aka earnings on 8/4). Much much more likely to press into gap fill to 500 territory imminently: 489.1 yearly pivot line (blue dashed line) first, then 498.45 quarterly pivot (grey dashed line) next. IF we push into that area before earnings, I will likely offload some shares and sell the replacement equivalent in puts following the decent sized October 420 put sale I caught across the tape Friday. Would happily take re-assignment there if it were to come. A lot of post-ER movement is going to come down to Journavx commentary/guidance IMO even though actual revenue is nominal at this point. $IBB $XBI $LABU
0 · Reply
SmartRetail90
SmartRetail90 Jul. 27 at 12:08 PM
$VRTX come to ANAB JP Morgan just gave it a $80 PT, stock is trading at 27 with 53% short interest! These are the setups that trigger a violent short squeeze. Don't miss out 👉🏻 ANAB
0 · Reply
Prester_John
Prester_John Jul. 26 at 5:37 PM
$VRTX I THINK THE JARVIS FLOW POST LISTED BELOW IS 6 MONTHS OUT OF DATE (AT LEAST THIS IS WHAT I FOUND). SAME MESSAGE ON TIP RANKS 12/24 2024 https://stocktwits.com/JarvisFlow/message/622232165
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Whiskeyunderthebed
Whiskeyunderthebed Jul. 25 at 5:59 PM
$VRTX But according to Guggenheim’s July 15 note, these two products are unlikely to contribute strongly to Vertex’s topline in the second quarter. Guggenheim forecasts Q2 Casgevy revenue to hit $35 million, ahead of the $25 million consensus, approaching a “potential inflection” during the fourth quarter. Vertex is unlikely to even include Journavx sales in its quarterly report, according to the analyst firm.
1 · Reply
kamenrider888
kamenrider888 Jul. 24 at 3:20 PM
$VRTX where are all the bot bulls now?😂😂 down down down...Like I said, OVERPRICED.
0 · Reply
JarvisFlow
JarvisFlow Jul. 24 at 10:00 AM
RBC Capital has adjusted their stance on Vertex Pharmaceuticals ( $VRTX ), setting the rating to Sector Perform with a target price of 451 → 400.
1 · Reply
AAUS1
AAUS1 Jul. 23 at 3:50 PM
$VRTX I’m ok
0 · Reply