Market Cap 6.89B
Revenue (ttm) 705.14M
Net Income (ttm) -453.90M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -64.37%
Debt to Equity Ratio 0.09
Volume 1,859,900
Avg Vol 2,004,992
Day's Range N/A - N/A
Shares Out 159.39M
Stochastic %K 50%
Beta 0.25
Analysts Strong Sell
Price Target $57.87

Company Profile

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treat...

Industry: Biotechnology
Sector: Healthcare
Phone: 760 931 9200
Address:
2855 Gazelle Court, Carlsbad, United States
jewell69
jewell69 Aug. 23 at 3:18 PM
Did another $TTD profit taking I still need to study $IONS as of now it is a nothing burger 8/21 drug approval for hereditary angioedema
0 · Reply
onefryshy
onefryshy Aug. 22 at 5:09 PM
$IONS sure, glad everybody updated their target price on this stock. That gives me a chance to buy at the double bottom...
1 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 4:20 PM
Citigroup has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Buy with a price target of 69.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 1:08 PM
Piper Sandler has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 65.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 1:01 PM
Barclays has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 58.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 12:30 PM
Wells Fargo has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 82.
0 · Reply
Thestocktraderhubzee
Thestocktraderhubzee Aug. 22 at 12:30 PM
$IONS Wells Fargo Maintains Overweight on Ionis Pharmaceuticals, Raises Price Target to $82
0 · Reply
Quantumup
Quantumup Aug. 22 at 12:07 PM
Wells Fargo⬆️ $IONS $82 wass $77/Overweight~sees momentum in $IONS's commercial and near-commercial programs in the near term. $TAK $BCRX $PHGUF $KALV $NTLA Piper Sandler⬆️ $IONS' PT to $65 from $62 and reiterated at Overweight: Remain Overweight rated on $IONS shares following the on-time FDA approval for Dawnzera (donidalorsen) in hereditary angioedema (HAE) in adult and pediatric patients 12+, marking the company's second independent product approval/launch. The label is largely in-line with expectations, including both Q4W and Q8W dosing intervals and, not surprisingly in our view, switching data was left off (but has been published and can be promoted). We're encouraged by $IONS' commentary around the experienced sales team in allergy and immunology (with direct HAE experience) and other commercial preparations, and based on HAE primarily being a switch market, we expect gradual but broad uptake. Remain buyers with a new $65 PT.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 11:30 AM
HC Wainwright & Co. has adjusted their stance on Ionis Pharmaceuticals ( $IONS ), setting the rating to Buy with a target price of 65 → 70.
0 · Reply
StocktwitsNews
StocktwitsNews Aug. 22 at 3:31 AM
Retail Traders Pile Into Ionis As Wall Street Hikes Price Targets On FDA Approval Of Swelling Disorder Therapy $IONS https://stocktwits.com/news/equity/markets/retail-traders-pile-into-ionis-as-wall-street-hikes-price-targets-on-fda-approval-of-swelling-disorder-therapy/chsmoACRdi6
0 · Reply
Latest News on IONS
US FDA approves Ionis' drug for rare genetic disorder

Aug 21, 2025, 11:58 AM EDT - 2 days ago

US FDA approves Ionis' drug for rare genetic disorder


Ionis to hold second quarter 2025 financial results webcast

Jul 16, 2025, 7:05 AM EDT - 5 weeks ago

Ionis to hold second quarter 2025 financial results webcast


Ionis to host 2025 virtual Annual Meeting of Stockholders

May 6, 2025, 7:05 AM EDT - 3 months ago

Ionis to host 2025 virtual Annual Meeting of Stockholders


Ionis reports first quarter 2025 financial results

Apr 30, 2025, 7:00 AM EDT - 4 months ago

Ionis reports first quarter 2025 financial results


Ionis to host expert panel discussion on sHTG

Apr 3, 2025, 7:05 AM EDT - 5 months ago

Ionis to host expert panel discussion on sHTG


Ionis to present at upcoming investor conferences

Mar 31, 2025, 7:05 AM EDT - 5 months ago

Ionis to present at upcoming investor conferences


Ionis Pharmaceuticals: Promising Growth From Tryngolza Approval

Dec 23, 2024, 7:30 AM EST - 8 months ago

Ionis Pharmaceuticals: Promising Growth From Tryngolza Approval


US FDA approves Ionis Pharma's genetic disorder drug

Dec 19, 2024, 5:18 PM EST - 8 months ago

US FDA approves Ionis Pharma's genetic disorder drug


Ionis reports third quarter 2024 financial results

Nov 6, 2024, 7:00 AM EST - 10 months ago

Ionis reports third quarter 2024 financial results


Ionis to hold third quarter 2024 financial results webcast

Oct 23, 2024, 7:05 AM EDT - 10 months ago

Ionis to hold third quarter 2024 financial results webcast


Ionis announces pricing of $500.3 million public offering

Sep 9, 2024, 9:10 PM EDT - 1 year ago

Ionis announces pricing of $500.3 million public offering


jewell69
jewell69 Aug. 23 at 3:18 PM
Did another $TTD profit taking I still need to study $IONS as of now it is a nothing burger 8/21 drug approval for hereditary angioedema
0 · Reply
onefryshy
onefryshy Aug. 22 at 5:09 PM
$IONS sure, glad everybody updated their target price on this stock. That gives me a chance to buy at the double bottom...
1 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 4:20 PM
Citigroup has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Buy with a price target of 69.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 1:08 PM
Piper Sandler has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 65.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 1:01 PM
Barclays has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 58.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 12:30 PM
Wells Fargo has updated their rating for Ionis Pharmaceuticals ( $IONS ) to Overweight with a price target of 82.
0 · Reply
Thestocktraderhubzee
Thestocktraderhubzee Aug. 22 at 12:30 PM
$IONS Wells Fargo Maintains Overweight on Ionis Pharmaceuticals, Raises Price Target to $82
0 · Reply
Quantumup
Quantumup Aug. 22 at 12:07 PM
Wells Fargo⬆️ $IONS $82 wass $77/Overweight~sees momentum in $IONS's commercial and near-commercial programs in the near term. $TAK $BCRX $PHGUF $KALV $NTLA Piper Sandler⬆️ $IONS' PT to $65 from $62 and reiterated at Overweight: Remain Overweight rated on $IONS shares following the on-time FDA approval for Dawnzera (donidalorsen) in hereditary angioedema (HAE) in adult and pediatric patients 12+, marking the company's second independent product approval/launch. The label is largely in-line with expectations, including both Q4W and Q8W dosing intervals and, not surprisingly in our view, switching data was left off (but has been published and can be promoted). We're encouraged by $IONS' commentary around the experienced sales team in allergy and immunology (with direct HAE experience) and other commercial preparations, and based on HAE primarily being a switch market, we expect gradual but broad uptake. Remain buyers with a new $65 PT.
0 · Reply
JarvisFlow
JarvisFlow Aug. 22 at 11:30 AM
HC Wainwright & Co. has adjusted their stance on Ionis Pharmaceuticals ( $IONS ), setting the rating to Buy with a target price of 65 → 70.
0 · Reply
StocktwitsNews
StocktwitsNews Aug. 22 at 3:31 AM
Retail Traders Pile Into Ionis As Wall Street Hikes Price Targets On FDA Approval Of Swelling Disorder Therapy $IONS https://stocktwits.com/news/equity/markets/retail-traders-pile-into-ionis-as-wall-street-hikes-price-targets-on-fda-approval-of-swelling-disorder-therapy/chsmoACRdi6
0 · Reply
moses_ametuer
moses_ametuer Aug. 21 at 10:25 PM
$IONS next earnings will be the real mover. PDUFA priced in
3 · Reply
johnnygogogo
johnnygogogo Aug. 21 at 9:24 PM
$IONS today is more proof that there is absolutely no reason to try to PDUFA trade anymore. You think you’re skating to where the puck is going but the casino just places the puck wherever they want it and whenever they want to. @skeezbag
1 · Reply
GMH21
GMH21 Aug. 21 at 8:37 PM
$IONS I think the one analyst question got it right: So if you are stating peak sales of $500M, at list price, that would be a little over 700 patients. That would represent about 10% of HAE patients. Also, about 20% of patients switch treatments every year and 80% of patients are looking for better alternatives, so I suspect they will be at 700 patients by Q4 2026. Average pricing may be a bit lower than list due to discounts, but I think this will ramp quicker than most new drugs coming to market.
0 · Reply
Jabed206
Jabed206 Aug. 21 at 6:49 PM
$IONS waiting for updated analyst reports
1 · Reply
jvbiotek
jvbiotek Aug. 21 at 6:19 PM
$IONS Had same experience with PGEN and TNXP last week. Both received FDA approvals but opposite impact on price. PGEN went up 75% after halt, but TNXP went down 15%. Hoping for good run with this stock
0 · Reply
topstockalerts
topstockalerts Aug. 21 at 6:16 PM
$IONS making a move.. keep an eye ..👀..
0 · Reply
Robcat
Robcat Aug. 21 at 5:52 PM
$IONS Be patient, once this baby awake, it will RUN.
0 · Reply
Mookins
Mookins Aug. 21 at 5:38 PM
$IONS People need to chill. thinking this will act like a penny stock blow my mind, bigger = slower moves. its not a fast pump and dump. give it some time to cook.
0 · Reply
Jabed206
Jabed206 Aug. 21 at 5:28 PM
$IONS company is huge ship $6 billion plus
0 · Reply
Smellmahass
Smellmahass Aug. 21 at 5:26 PM
$IONS Looks like it will end up red today.
0 · Reply
Jabed206
Jabed206 Aug. 21 at 5:11 PM
$IONS conference finished ? Any news on price?
1 · Reply
M105
M105 Aug. 21 at 4:57 PM
$IONS So weird! Approved with no price action, yet, OT is $83. Anyone cares to explain?
1 · Reply