Market Cap 13.23B
Revenue (ttm) 705.14M
Net Income (ttm) -453.90M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -64.37%
Debt to Equity Ratio 0.00
Volume 1,885,100
Avg Vol 2,436,612
Day's Range N/A - N/A
Shares Out 161.97M
Stochastic %K 34%
Beta 0.28
Analysts Strong Sell
Price Target $90.22

Company Profile

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treat...

Industry: Biotechnology
Sector: Healthcare
Phone: 760 931 9200
Address:
2855 Gazelle Court, Carlsbad, United States
Quantumup
Quantumup Jan. 13 at 1:18 PM
Piper Sandler⬆️ $ARWR's PT to $110 and reit'd at Overweight $IONS $WVE $RHHBY $REGN TEVA Piper Sandler said in its note: Arrowhead launched Redemplo for familial chylomicronemia syndrome (FCS), and we conservatively forecast sales of $8.4 million in FY:26 to grow to $41.6 million in FY:27. We are confident Arrowhead will report positive Phase III Redemplo data in severe hypertriglyceridemia in 3Q:26 with potential blockbuster label expansion in CY:27. Arrowhead reported impressive weight and fat loss data from the ongoing Phase I/II studies of ARO-INHBE and ARO-ALK7 with more data this year. Arrowhead initiated Phase I/ lla studies of ARO-DIMER-PA for ASCVD and ARO-MAPT for early Alzheimer's disease patients, both with initial data in 2026. Arrowhead issued $700 million in zero coupon convertible debt and raised $230 million in equity bringing pro forma cash to ~$2.09 billion and debt to ~$955 million. We reiterate our Overweight rating and are increasing our price target to $110 from $100.
0 · Reply
Quantumup
Quantumup Jan. 12 at 7:42 PM
TD Cowen reiterated $BBIO Buy; PT 95 $ALNY $PFE $AZN - $IONS NVO Here's what TD Cowen had to say: Attruby Q4 sales of $146MM beat expectations by 9%, leading to an impressive first full year of sales of $362MM. New patient starts surged with an estimated 25% NBRx share, signaling growing market leadership. The late-stage pipeline anchors the next leg of growth, with Phase III wins for LGMD21 and ADH1, while infi's Q1 data could easily support a best-in-class profile — each with $1B+ potential.
0 · Reply
REDBEAR
REDBEAR Jan. 9 at 7:28 PM
$IONS guys, funnymentally what's happening? It looks like a b/o. I only look at charts so appreciate the info. thanks.
1 · Reply
StockConsultant
StockConsultant Jan. 8 at 2:25 PM
$IONS Ionis Pharmaceuticals stock with a top of range breakout watch, target 92 area
0 · Reply
skeezbag
skeezbag Jan. 8 at 1:52 PM
$ARWR 78% short volume yesterday. Short the common the day any converts are announced by the hedgies. It doesn't last though. See $IONS $ALNY Overall 0% interest on converts in smid bio means arrowhead has arrived and investors want the common upside
1 · Reply
victorgn
victorgn Jan. 7 at 7:48 PM
$IONS tgt: $90
0 · Reply
WAJeff
WAJeff Jan. 7 at 3:56 PM
$IONS Sold for small gains at $84, $86.15 is an ath but this was also above $81 in 2019 and dropped to a third of that in Nov 2021. Bios are a roller coaster.
1 · Reply
rodgerdelta9er
rodgerdelta9er Jan. 7 at 3:55 PM
$IONS Are we at ATH?
0 · Reply
Joe_Mama
Joe_Mama Jan. 7 at 3:17 PM
$IONS Next target $86.60
0 · Reply
JFDI
JFDI Jan. 7 at 3:17 PM
$IONS busting 3wt higher.
0 · Reply
Latest News on IONS
Biogen Completes Acquisition of Alcyone Therapeutics

Nov 14, 2025, 4:05 PM EST - 2 months ago

Biogen Completes Acquisition of Alcyone Therapeutics

BIIB


Ionis to present at upcoming investor conferences

Nov 12, 2025, 4:00 PM EST - 2 months ago

Ionis to present at upcoming investor conferences


Ionis to hold third quarter 2025 financial results webcast

Oct 16, 2025, 7:05 AM EDT - 3 months ago

Ionis to hold third quarter 2025 financial results webcast


Ionis' brain disorder drug shows promise in clinical trial

Sep 22, 2025, 7:10 AM EDT - 4 months ago

Ionis' brain disorder drug shows promise in clinical trial


Ionis to host investors and analysts for Innovation Day 2025

Sep 8, 2025, 4:00 PM EDT - 4 months ago

Ionis to host investors and analysts for Innovation Day 2025


Is The 35% Rally In IONS Stock Just The Beginning?

Sep 3, 2025, 10:41 AM EDT - 4 months ago

Is The 35% Rally In IONS Stock Just The Beginning?


mRNA Biotechs - Long-Term Value Risks Abound

Aug 28, 2025, 6:20 AM EDT - 4 months ago

mRNA Biotechs - Long-Term Value Risks Abound

ALNY BNTX DHR GRAL ILMN MRNA RGEN


US FDA approves Ionis' drug for rare genetic disorder

Aug 21, 2025, 11:58 AM EDT - 5 months ago

US FDA approves Ionis' drug for rare genetic disorder


Quantumup
Quantumup Jan. 13 at 1:18 PM
Piper Sandler⬆️ $ARWR's PT to $110 and reit'd at Overweight $IONS $WVE $RHHBY $REGN TEVA Piper Sandler said in its note: Arrowhead launched Redemplo for familial chylomicronemia syndrome (FCS), and we conservatively forecast sales of $8.4 million in FY:26 to grow to $41.6 million in FY:27. We are confident Arrowhead will report positive Phase III Redemplo data in severe hypertriglyceridemia in 3Q:26 with potential blockbuster label expansion in CY:27. Arrowhead reported impressive weight and fat loss data from the ongoing Phase I/II studies of ARO-INHBE and ARO-ALK7 with more data this year. Arrowhead initiated Phase I/ lla studies of ARO-DIMER-PA for ASCVD and ARO-MAPT for early Alzheimer's disease patients, both with initial data in 2026. Arrowhead issued $700 million in zero coupon convertible debt and raised $230 million in equity bringing pro forma cash to ~$2.09 billion and debt to ~$955 million. We reiterate our Overweight rating and are increasing our price target to $110 from $100.
0 · Reply
Quantumup
Quantumup Jan. 12 at 7:42 PM
TD Cowen reiterated $BBIO Buy; PT 95 $ALNY $PFE $AZN - $IONS NVO Here's what TD Cowen had to say: Attruby Q4 sales of $146MM beat expectations by 9%, leading to an impressive first full year of sales of $362MM. New patient starts surged with an estimated 25% NBRx share, signaling growing market leadership. The late-stage pipeline anchors the next leg of growth, with Phase III wins for LGMD21 and ADH1, while infi's Q1 data could easily support a best-in-class profile — each with $1B+ potential.
0 · Reply
REDBEAR
REDBEAR Jan. 9 at 7:28 PM
$IONS guys, funnymentally what's happening? It looks like a b/o. I only look at charts so appreciate the info. thanks.
1 · Reply
StockConsultant
StockConsultant Jan. 8 at 2:25 PM
$IONS Ionis Pharmaceuticals stock with a top of range breakout watch, target 92 area
0 · Reply
skeezbag
skeezbag Jan. 8 at 1:52 PM
$ARWR 78% short volume yesterday. Short the common the day any converts are announced by the hedgies. It doesn't last though. See $IONS $ALNY Overall 0% interest on converts in smid bio means arrowhead has arrived and investors want the common upside
1 · Reply
victorgn
victorgn Jan. 7 at 7:48 PM
$IONS tgt: $90
0 · Reply
WAJeff
WAJeff Jan. 7 at 3:56 PM
$IONS Sold for small gains at $84, $86.15 is an ath but this was also above $81 in 2019 and dropped to a third of that in Nov 2021. Bios are a roller coaster.
1 · Reply
rodgerdelta9er
rodgerdelta9er Jan. 7 at 3:55 PM
$IONS Are we at ATH?
0 · Reply
Joe_Mama
Joe_Mama Jan. 7 at 3:17 PM
$IONS Next target $86.60
0 · Reply
JFDI
JFDI Jan. 7 at 3:17 PM
$IONS busting 3wt higher.
0 · Reply
OptionRunners
OptionRunners Jan. 7 at 3:15 PM
$IONS Calls up to $2.30 now
0 · Reply
Joe_Mama
Joe_Mama Jan. 7 at 3:11 PM
$IONS NICE! And thanks to IONS!
0 · Reply
kate8delgado8
kate8delgado8 Jan. 7 at 12:48 PM
0 · Reply
Dr_Stoxx
Dr_Stoxx Jan. 7 at 12:09 PM
$IONS: just printed a 3rd "pocket pivot" bullish buy setup since the September power gap. Move to the low 90's on tap. #IBDPartner @InvestorsBusinessDaily @MarketSurge
1 · Reply
Dr_Stoxx
Dr_Stoxx Jan. 7 at 12:03 PM
$IONS: love this setup. 4th pocket pivot since the power gap.
0 · Reply
notreload_ai
notreload_ai Jan. 7 at 11:35 AM
$GSK and $IONS announce breakthrough results for bepirovirsen, a potential first-in-class treatment offering functional cure for chronic hepatitis B in just six months. https://notreload.xyz/gsk-ionis-announce-major-win-against-hepatitis-b-in-landmark-trials/
0 · Reply
TradeTracs
TradeTracs Jan. 6 at 12:19 AM
Some absolute HEAT to start the week/new year! lets get those accounts some buffer room on the YTD %💪📈 $JAZZ continued breakout from fridays close $AMTM sitting pretty after fridays entry thru 30 $WDC multiple entries prior to today, but new ATH's! $IONS gearing up for potential ATH test with a 50sma support play $CVS just mentioned again cooking as well👀 Lets keep that momentum building with TradeTracs™️
0 · Reply
OptionRunners
OptionRunners Jan. 2 at 5:18 PM
$IONS buyer of the January 16th $87.50 calls 4,000 times for $1.02
2 · Reply
RonIsWrong
RonIsWrong Jan. 2 at 3:33 PM
$IONS 4000 of the Jan 87.50 calls. odd
1 · Reply
BillionerOfKing
BillionerOfKing Dec. 30 at 12:52 PM
$IONS Current Stock Price: $79.87 Contracts to trade: $80 IONS Jan 16 2026 Call Entry: $3.11 Exit: $5.48 ROI: 76% Hold ~26 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
TradeTracs
TradeTracs Dec. 30 at 12:54 AM
$IONS - Strong recent earnings - Strong relative strength - Tightening price action
0 · Reply
BioRich
BioRich Dec. 28 at 5:32 PM
$ALT $SNY $IVA $IONS $MDGL Don't forget...
0 · Reply