Apr. 23 at 2:45 AM
$EXEL we had a great reason to be up!!! litespark-012 was a major bust!!!!!
Merck MRK, along with its partner Eisai, announced that the phase III LITESPARK-012 study, which evaluated Keytruda-based triplet regimens for the first-line treatment of patients with advanced clear cell renal cell carcinoma (RCC), failed to meet its primary endpoints.
The LITESPARK-012 study evaluated either the triplet therapy of Keytruda plus Lenvima plus Welireg or MK-1308A (a coformulation of Keytruda and quavonlimab – MRK’s investigational anti-CTLA-4 antibody) plus Lenvima versus Keytruda plus Lenvima for the first-line treatment of patients with advanced clear cell RCC.