Yi_YandH
Sep 28, 12:00 PM
$ICU Vantive(
$BAX):
The SCD fits easily, as does Vantive, as our International, upfront
$10,000,0000.00 PREMIUM paying partner with the SCD-PED. The 20%-25% royalties after device cost reimbursement plus the 10%-15%, for incidentals. International royalties will become a reality in 3-18 months. which is the necessary timeframe for the required foreign government medical organization’s approvals. That’s a lot of JACK.
SeaStar and
$FMS will handle US sales, training and distribution of the Adult device, next summer.
SeaStar will ramp up new hires for the training, sales and distribution of the pediatric device here in the USA after the CMS billing codes become active late this week. The SAVE Registry will become unrequired in the coming 2-4 weeks, even sooner, hopefully. 4th qtr. revenues should be quite impressive.
-Prismaflex machine, a staple of the Vantive acute therapy portfolio, serves as the primary pump and fluid management platform for this configuration:
Physical Mounting: When pairing the devices, an SCD securing bracket must be physically affixed to the right side of the Prismaflex control unit using pre-attached adhesive strips or zip-ties.
Tubing Connections: The specialized SCD blood tubing set connects directly in series with the standard Vantive Prismaflex hemofilter tubing sets (such as the HF20, HF1000, or HF1400).
Target Indication & MechanismPatient Population: The therapy is indicated for critically ill pediatric patients weighing 10 kg or more (up to 22 years of age) suffering from acute kidney injury (AKI) due to sepsis or septic conditions.
Immunomodulatory Role: While the Vantive Prismaflex manages fluid balance and metabolic clearance, the SCD-PED acts as a disease-modifying immunomodulator. It works within the extracorporeal circuit to target, desensitize, and deactivate over-activated neutrophils and monocytes, helping to halt the hyperinflammatory cascade ("cytokine storm") that causes organ damage.Clinical & Operational PrerequisitesRegional Citrate Anticoagulation (RCA): The SCD-PED mechanism relies strictly on a low-calcium environment to selectively bind hyper-inflammatory white blood cells. Clinicians must use regional citrate anticoagulation protocols on the Prismaflex system to maintain a circuit ionized calcium (iCa²⁺) level below 0.40 mmol/L.Standard Vantive Disposables: The protocol requires standard Prismaflex components, zero-calcium bicarbonate solution, and accessory connectors for calcium and citrate infusions to manage the anticoagulation loop effectively.
2 replies