Jun. 23 at 3:07 PM
$LXRX $NVO $LLY $VTRS Sota triggers Insulin production-via triggering GLPproduction!! via activating NATURAL GLP1, *NOT SYNTHETIC*, like
$LLY or
$NVO .
Did you know Sotagliflozin (
$LXRX) triggers the same GLP-1 hormone as Ozempic? Here’s the exact science:
Standard drugs only block SGLT2 (kidneys). Sota is a DUAL inhibitor, also blocking SGLT1 (in the gut).
The Gut Mechanism:
Blocking SGLT1 pushes glucose further down the intestines, naturally triggering a surge of GLP-1.
👉 For Type 2: This GLP-1 surge successfully signals the pancreas to produce insulin.
👉 For Type 1: A T1D pancreas can't make insulin. BUT, the GLP-1 surge suppresses glucagon (stops the liver from dumping sugar) and slows digestion.
The Result?
Massively blunted post-meal spikes, flatter curves, and a drastic reduction in the injected mealtime insulin needed. Pure SGLT2s miss this gut bonus entirely!
🧬 Read the peer-reviewed clinical data on the SGLT1/GLP-1 pathway here:
https://pmc.ncbi.nlm.nih.gov/articles/PMC4831906/
#T1D
