Market Cap 417.91M
Revenue (ttm) 31.08M
Net Income (ttm) -200.40M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -644.79%
Debt to Equity Ratio 0.43
Volume 1,688,000
Avg Vol 2,675,504
Day's Range N/A - N/A
Shares Out 363.40M
Stochastic %K 71%
Beta 1.26
Analysts Sell
Price Target $2.75

Company Profile

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company offers Sotagliflozin, an orally-delivered small molecule drug to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease or CKD, and other cardiovascular risk factors. Its...

Industry: Biotechnology
Sector: Healthcare
Phone: 281 863 3000
Fax: 281 863 8088
Address:
2445 Technology Forest Boulevard, 11th Floor, The Woodlands, United States
KPP2626
KPP2626 Sep. 14 at 5:34 AM
$LXRX The key points are: - The timeline presented to investors was "EOP2 at the end of the year → Phase III to begin early the following year." - At the same time, management has repeatedly stated that "Phase III will not be funded by the company itself; the partner will cover the costs." In other words, they acknowledge that Phase III cannot be implemented unless a partnership is decided. - Partnership negotiations have been progressing well behind the scenes, and unless they were confident of success, they would not have presented a specific timeline.
1 · Reply
Beebomb
Beebomb Sep. 14 at 2:04 AM
$LXRX I keep hoping an independent third party will make an enthusiastic statement confirming the efficacy demonstrated in Phase II in a way that alerts the market to the phenomenal potential of a non-opioid for chronic pain. These conferences, alas, repeat the same old, same old in a way that excites yawns.
1 · Reply
buconm
buconm Sep. 14 at 12:14 AM
$LXRX $NVO Even more dots connecting Lexi and Novo. Mike became Scaled Insights AI BoA, one of collaboration partners is Novo. (Sotagliflozin) Zynquista/T1D Type D meeting additional data are from STENA studies that are funded by Novo. Presentation by Rodica about Pilavapadin/DPN was sponsored by Novo. And ofc LX9851 partnership. So Novo were/is involved in all of the drugs in Lexi pipeline, that can't be
4 · Reply
gucag006
gucag006 Sep. 13 at 10:02 PM
$LXRX Pilavapadin is currently being tested for DPNP, a sizeable market but a subset of one of the biggest pharmaceutical markets: "The non-opioid pain management market has significant growth potential, expected to reach between $70 billion and $91 billion by 2030-2034, with a compound annual growth rate (CAGR) of 7.7% to 8.1%. This expansion is driven by the global opioid crisis, leading to increased demand for safer alternatives, supported by rising R&D, government initiatives, technological advancements in devices and formulations, and the growing elderly population experiencing chronic pain." There're many ways that this could be played out. One of those is multi-$B's partnership deal, and the other is to sell it outright, which I believe should be worth between $5B ($15/sh) to $8B ($24/sh) or more. Then we still have Inpefa (HF, HCM, MI, stroke), LX9851 and a handful of drug candidate from gene-knockout animal trials plus T1DM.
3 · Reply
Dooright
Dooright Sep. 13 at 8:20 PM
$LXRX Holy crap! What is the meaning of life? 😆 Doc C. 🤓
1 · Reply
Thekareemofthecrop
Thekareemofthecrop Sep. 13 at 7:55 PM
$LXRX for those who have been in this stock longer than me (April 2025) what was the build up to the Novo partnership like? Was the weight loss drug presented anywhere? Was there a lot of hype? How did that process compare to the two drugs we have now?
1 · Reply
Twenerz
Twenerz Sep. 13 at 7:39 PM
$LXRX I would be surprised if a partnership is announced before the end of P2 meeting with the agency. Much more clarity for potential partners after this. Could be wrong of course but this is my suspicion
0 · Reply
Daywalker777
Daywalker777 Sep. 13 at 7:17 PM
$LXRX would be amazing to wake up Monday morning with a huge partnership deal with big pharma for neuropathic pain. They are presenting the studied results at multiple conferences … one would assume that the results must be good otherwise why share at multiple conferences?? We can only hope.
2 · Reply
Marta22
Marta22 Sep. 13 at 4:23 PM
$LXRX I'm very curious about the lecture at NeuroDiab, September 11-14 in Bucharest, Romania: ,,Results from recently completed clinical trials of Pilavapadin, an oral, non-opioid, AAK1 inhibitor for peripheral diabetics,,. I hope there will be some excellent data on the 10 mg dose.
0 · Reply
MYFLAUT
MYFLAUT Sep. 13 at 1:43 PM
$LXRX as soon as anyone gets a interpretation of the presentation we would appreciate it if you posted
0 · Reply
Latest News on LXRX
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Lexicon Appoints Scott Coiante as Chief Financial Officer

Jan 2, 2025, 8:00 AM EST - 9 months ago

Lexicon Appoints Scott Coiante as Chief Financial Officer


US FDA declines to approve Lexicon Pharma's add-on diabetes drug

Dec 20, 2024, 4:46 PM EST - 9 months ago

US FDA declines to approve Lexicon Pharma's add-on diabetes drug


Lexicon Appoints Ivan H. Cheung to Board of Directors

Nov 20, 2024, 4:05 PM EST - 10 months ago

Lexicon Appoints Ivan H. Cheung to Board of Directors


KPP2626
KPP2626 Sep. 14 at 5:34 AM
$LXRX The key points are: - The timeline presented to investors was "EOP2 at the end of the year → Phase III to begin early the following year." - At the same time, management has repeatedly stated that "Phase III will not be funded by the company itself; the partner will cover the costs." In other words, they acknowledge that Phase III cannot be implemented unless a partnership is decided. - Partnership negotiations have been progressing well behind the scenes, and unless they were confident of success, they would not have presented a specific timeline.
1 · Reply
Beebomb
Beebomb Sep. 14 at 2:04 AM
$LXRX I keep hoping an independent third party will make an enthusiastic statement confirming the efficacy demonstrated in Phase II in a way that alerts the market to the phenomenal potential of a non-opioid for chronic pain. These conferences, alas, repeat the same old, same old in a way that excites yawns.
1 · Reply
buconm
buconm Sep. 14 at 12:14 AM
$LXRX $NVO Even more dots connecting Lexi and Novo. Mike became Scaled Insights AI BoA, one of collaboration partners is Novo. (Sotagliflozin) Zynquista/T1D Type D meeting additional data are from STENA studies that are funded by Novo. Presentation by Rodica about Pilavapadin/DPN was sponsored by Novo. And ofc LX9851 partnership. So Novo were/is involved in all of the drugs in Lexi pipeline, that can't be
4 · Reply
gucag006
gucag006 Sep. 13 at 10:02 PM
$LXRX Pilavapadin is currently being tested for DPNP, a sizeable market but a subset of one of the biggest pharmaceutical markets: "The non-opioid pain management market has significant growth potential, expected to reach between $70 billion and $91 billion by 2030-2034, with a compound annual growth rate (CAGR) of 7.7% to 8.1%. This expansion is driven by the global opioid crisis, leading to increased demand for safer alternatives, supported by rising R&D, government initiatives, technological advancements in devices and formulations, and the growing elderly population experiencing chronic pain." There're many ways that this could be played out. One of those is multi-$B's partnership deal, and the other is to sell it outright, which I believe should be worth between $5B ($15/sh) to $8B ($24/sh) or more. Then we still have Inpefa (HF, HCM, MI, stroke), LX9851 and a handful of drug candidate from gene-knockout animal trials plus T1DM.
3 · Reply
Dooright
Dooright Sep. 13 at 8:20 PM
$LXRX Holy crap! What is the meaning of life? 😆 Doc C. 🤓
1 · Reply
Thekareemofthecrop
Thekareemofthecrop Sep. 13 at 7:55 PM
$LXRX for those who have been in this stock longer than me (April 2025) what was the build up to the Novo partnership like? Was the weight loss drug presented anywhere? Was there a lot of hype? How did that process compare to the two drugs we have now?
1 · Reply
Twenerz
Twenerz Sep. 13 at 7:39 PM
$LXRX I would be surprised if a partnership is announced before the end of P2 meeting with the agency. Much more clarity for potential partners after this. Could be wrong of course but this is my suspicion
0 · Reply
Daywalker777
Daywalker777 Sep. 13 at 7:17 PM
$LXRX would be amazing to wake up Monday morning with a huge partnership deal with big pharma for neuropathic pain. They are presenting the studied results at multiple conferences … one would assume that the results must be good otherwise why share at multiple conferences?? We can only hope.
2 · Reply
Marta22
Marta22 Sep. 13 at 4:23 PM
$LXRX I'm very curious about the lecture at NeuroDiab, September 11-14 in Bucharest, Romania: ,,Results from recently completed clinical trials of Pilavapadin, an oral, non-opioid, AAK1 inhibitor for peripheral diabetics,,. I hope there will be some excellent data on the 10 mg dose.
0 · Reply
MYFLAUT
MYFLAUT Sep. 13 at 1:43 PM
$LXRX as soon as anyone gets a interpretation of the presentation we would appreciate it if you posted
0 · Reply
Dooright
Dooright Sep. 13 at 12:12 PM
$LXRX Here you go… Doc C. 🤓 The Central European Summer Time (CEST) is 6 hours ahead of Eastern Standard Time (EST).
1 · Reply
Dooright
Dooright Sep. 13 at 11:21 AM
$LXRX Good morning everyone. Big day today! 👍 Doc C. 🤓 NeuroDiab, September 11-14 in Bucharest, Romania: - Lecture 3: New Promise for Painful Diabetic Neuropathy: Results from recently finished clinical trials of Pilavapadin, an oral, non-opioid, AAK1 inhibitor for diabetic peripheral neuropathic pain - Date: Saturday, September 13, 2025 - Time: 11:15 a.m. CEST - Presenter: Rodica Pop-Busui M.D., Ph.D., Jordan Schnitzer Chair in Diabetes, Professor of Medicine and Division Head, Endocrinology, Diabetes and Clinical Nutrition Director, Harold Schnitzer Diabetes Center, Oregon Health & Science University
2 · Reply
KPP2626
KPP2626 Sep. 13 at 2:16 AM
$LXRX We asked the AI, "So, who do you think will be the partner for the Phase 3 trial of Pilavadin?" and here's the answer. Out of all the major pharmaceutical companies, NOVO's rival is the first choice? Are you serious?
2 · Reply
Anonymcq
Anonymcq Sep. 12 at 10:44 PM
$LXRX we are trading at fair market value here - need a major catalyst to move. I would exit my options position (and was looking to over the last month), but the small premium didn’t justify it so holding these until the end. Will likely take my initial $$$ off the table and let the profit ride as I do still believe a catalyst (BO or licensing) will hit and hit big - just need patience.
1 · Reply
Thekareemofthecrop
Thekareemofthecrop Sep. 12 at 9:47 PM
$LXRX we already know this but good to see the support and further exposure. Dr. Steve Edelman who lives with T1D is one of the biggest advocates for Sotagliflozin.
4 · Reply
123rickiek
123rickiek Sep. 12 at 9:16 PM
$LXRX Still on the upward trend!!!
0 · Reply
TAgurus
TAgurus Sep. 12 at 9:06 PM
1 · Reply
beachbroke
beachbroke Sep. 12 at 7:34 PM
0 · Reply
TAgurus
TAgurus Sep. 12 at 7:02 PM
$LXRX It is going to break.
4 · Reply
SocioCobb
SocioCobb Sep. 12 at 5:12 PM
$LXRX will explode at some point. Not going into the nuances concerning non-opiod options. Plenty to get excited about with 'ol Lexi. Slowly adding for now. Godspeed bulls...
0 · Reply
CatchTheCleanUpSet
CatchTheCleanUpSet Sep. 12 at 5:02 PM
$LXRX anybody else see a wedge pattern on the daily chart ? What happens next?
0 · Reply
Iman133
Iman133 Sep. 12 at 4:44 PM
$LXRX From chatgpt:
1 · Reply