Market Cap 7.42B
Revenue (ttm) 389.13M
Net Income (ttm) 204.83M
EPS (ttm) N/A
PE Ratio 38.00
Forward PE 32.20
Profit Margin 52.64%
Debt to Equity Ratio 0.00
Volume 148,760
Avg Vol 294,532
Day's Range N/A - N/A
Shares Out 29.23M
Stochastic %K 29%
Beta 0.49
Analysts Strong Sell
Price Target $324.30

Company Profile

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical tri...

Industry: Biotechnology
Sector: Healthcare
Phone: 412 586 5830
Address:
2100 Wharton Street, Suite 701, Pittsburgh, United States
1GreenDay99RedDays
1GreenDay99RedDays Mar. 2 at 8:43 PM
$KRYS been a monster for 5 years i comment and blamo
0 · Reply
GorillaTrades
GorillaTrades Feb. 27 at 8:22 PM
Top 3 #momentum #stocks In The GorillaTrades #portfolio This Week: Cboe Global Markets $CBOE +4.7%, Krystal Biotechnology $KRYS +4.7%, and Agree Realty $ADC +3.5%
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 25 at 10:34 PM
$KRYS RSI: 52.04, MACD: 1.0698 Vol: 6.74, MA20: 273.76, MA50: 265.48 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
erevnon
erevnon Feb. 25 at 2:57 PM
Guggenheim maintains Krystal Biotech $KRYS at Buy and raises the price target from $224 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
Theflash88
Theflash88 Feb. 22 at 9:01 PM
$KRYS Well that big rally didn’t last long.
0 · Reply
wheresdannynow
wheresdannynow Feb. 20 at 8:22 PM
$KRYS is crushing it with Vyjuvek sales and pipeline wins. That’s what biotech patience looks like when it pays. While big caps like $LLY $NVO stay crowded, small caps can reprice hard when data lines up. $BIOV.CSE $BVAXF quietly stacking positive DPX data in ovarian, bladder, and breast cancer. Platform stories heat up fast once momentum builds. Biotech does not reward panic. It rewards positioning.
0 · Reply
Ventureville
Ventureville Feb. 20 at 3:57 PM
Q1 2026 is already lighting up biotech. $MBRX accelerating its AML trial. $KRYS beating on earnings. Multiple FDA decisions lined up across the sector. When biotech momentum builds, small caps move fast. $BIOV.CSE $BVAXF with HapTenix and BVX-0918 in ovarian cancer sits right in that wave. Rotation into biotech does not trickle. It snaps.
0 · Reply
erevnon
erevnon Feb. 18 at 7:31 PM
Citigroup maintains Krystal Biotech $KRYS at Buy and raises the price target from $336 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
ZacksResearch
ZacksResearch Feb. 18 at 5:08 PM
$KRYS just delivered an earnings twist — beat on EPS, miss on revenue. So what really matters here? 👀 KRYS topped Q4 estimates while Vyjuvek sales jumped 17%, locked in 660+ U.S. reimbursements, and pushed its gene therapy pipeline runway into 2026. That’s operational momentum, even with revenues missing the mark. Is this a setup for longer-term upside or a mixed signal? Get the full breakdown 👉 https://www.zacks.com/stock/news/2871431/krystal-biotech-q4-earnings-beat-estimates-revenues-miss-mark?cid=sm-stocktwits-2-2871431-teaser-34052&ADID=SYND_STOCKTWITS_TWEET_2_2871431_TEASER_34052
0 · Reply
ZacksResearch
ZacksResearch Feb. 18 at 4:08 PM
$KRYS earnings beat! 🚀 What drove the growth? Krystal Biotech's Q4 EPS of $1.70 beat the Zacks Consensus Estimate of $1.62, with revenue up 17.5% in the reported quarter, thanks to strong Vyjuvek sales. The stock is up 63.4% over the past year! 📈 Find out what’s next for KRYS here 👉 https://www.zacks.com/stock/news/2871431/krystal-biotech-q4-earnings-beat-estimates-revenues-miss-mark?cid=sm-stocktwits-2-2871431-body-34049&ADID=SYND_STOCKTWITS_TWEET_2_2871431_BODY_34049
0 · Reply
Latest News on KRYS
Krystal Biotech, Inc. (KRYS) Q4 2025 Earnings Call Transcript

Feb 17, 2026, 3:54 PM EST - 20 days ago

Krystal Biotech, Inc. (KRYS) Q4 2025 Earnings Call Transcript


Krystal Biotech: Beyond VYJUVEK Commercialization

Jan 16, 2026, 7:45 AM EST - 7 weeks ago

Krystal Biotech: Beyond VYJUVEK Commercialization


Krystal Biotech: Vyjuvek Gene Therapy Well Positioned For Growth

Nov 16, 2025, 9:00 AM EST - 4 months ago

Krystal Biotech: Vyjuvek Gene Therapy Well Positioned For Growth


Krystal Biotech, Inc. (KRYS) Q3 2025 Earnings Call Transcript

Nov 3, 2025, 11:46 AM EST - 4 months ago

Krystal Biotech, Inc. (KRYS) Q3 2025 Earnings Call Transcript


Krystal Biotech, Inc. (KRYS) Q2 2025 Earnings Call Transcript

Aug 4, 2025, 12:42 PM EDT - 7 months ago

Krystal Biotech, Inc. (KRYS) Q2 2025 Earnings Call Transcript


Krystal Biotech, Inc. (KRYS) Q1 2025 Earnings Call Transcript

May 6, 2025, 2:43 PM EDT - 11 months ago

Krystal Biotech, Inc. (KRYS) Q1 2025 Earnings Call Transcript


Krystal Biotech to Present at Upcoming Scientific Conferences

Apr 24, 2025, 8:00 AM EDT - 11 months ago

Krystal Biotech to Present at Upcoming Scientific Conferences


Krystal Biotech, Inc. (KRYS) Q4 2024 Earnings Call Transcript

Feb 19, 2025, 11:43 AM EST - 1 year ago

Krystal Biotech, Inc. (KRYS) Q4 2024 Earnings Call Transcript


Krystal Biotech to Present at Upcoming Investor Conferences

Nov 27, 2024, 7:00 AM EST - 1 year ago

Krystal Biotech to Present at Upcoming Investor Conferences


1GreenDay99RedDays
1GreenDay99RedDays Mar. 2 at 8:43 PM
$KRYS been a monster for 5 years i comment and blamo
0 · Reply
GorillaTrades
GorillaTrades Feb. 27 at 8:22 PM
Top 3 #momentum #stocks In The GorillaTrades #portfolio This Week: Cboe Global Markets $CBOE +4.7%, Krystal Biotechnology $KRYS +4.7%, and Agree Realty $ADC +3.5%
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 25 at 10:34 PM
$KRYS RSI: 52.04, MACD: 1.0698 Vol: 6.74, MA20: 273.76, MA50: 265.48 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
erevnon
erevnon Feb. 25 at 2:57 PM
Guggenheim maintains Krystal Biotech $KRYS at Buy and raises the price target from $224 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
Theflash88
Theflash88 Feb. 22 at 9:01 PM
$KRYS Well that big rally didn’t last long.
0 · Reply
wheresdannynow
wheresdannynow Feb. 20 at 8:22 PM
$KRYS is crushing it with Vyjuvek sales and pipeline wins. That’s what biotech patience looks like when it pays. While big caps like $LLY $NVO stay crowded, small caps can reprice hard when data lines up. $BIOV.CSE $BVAXF quietly stacking positive DPX data in ovarian, bladder, and breast cancer. Platform stories heat up fast once momentum builds. Biotech does not reward panic. It rewards positioning.
0 · Reply
Ventureville
Ventureville Feb. 20 at 3:57 PM
Q1 2026 is already lighting up biotech. $MBRX accelerating its AML trial. $KRYS beating on earnings. Multiple FDA decisions lined up across the sector. When biotech momentum builds, small caps move fast. $BIOV.CSE $BVAXF with HapTenix and BVX-0918 in ovarian cancer sits right in that wave. Rotation into biotech does not trickle. It snaps.
0 · Reply
erevnon
erevnon Feb. 18 at 7:31 PM
Citigroup maintains Krystal Biotech $KRYS at Buy and raises the price target from $336 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
ZacksResearch
ZacksResearch Feb. 18 at 5:08 PM
$KRYS just delivered an earnings twist — beat on EPS, miss on revenue. So what really matters here? 👀 KRYS topped Q4 estimates while Vyjuvek sales jumped 17%, locked in 660+ U.S. reimbursements, and pushed its gene therapy pipeline runway into 2026. That’s operational momentum, even with revenues missing the mark. Is this a setup for longer-term upside or a mixed signal? Get the full breakdown 👉 https://www.zacks.com/stock/news/2871431/krystal-biotech-q4-earnings-beat-estimates-revenues-miss-mark?cid=sm-stocktwits-2-2871431-teaser-34052&ADID=SYND_STOCKTWITS_TWEET_2_2871431_TEASER_34052
0 · Reply
ZacksResearch
ZacksResearch Feb. 18 at 4:08 PM
$KRYS earnings beat! 🚀 What drove the growth? Krystal Biotech's Q4 EPS of $1.70 beat the Zacks Consensus Estimate of $1.62, with revenue up 17.5% in the reported quarter, thanks to strong Vyjuvek sales. The stock is up 63.4% over the past year! 📈 Find out what’s next for KRYS here 👉 https://www.zacks.com/stock/news/2871431/krystal-biotech-q4-earnings-beat-estimates-revenues-miss-mark?cid=sm-stocktwits-2-2871431-body-34049&ADID=SYND_STOCKTWITS_TWEET_2_2871431_BODY_34049
0 · Reply
erevnon
erevnon Feb. 18 at 2:25 PM
Chardan Capital maintains Krystal Biotech $KRYS at Buy and raises the price target from $220 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
mikesterz7
mikesterz7 Feb. 17 at 8:49 PM
$KRYS Krystal’s Vyjuvek is a gene therapy approved for the treatment of Dystrophic Epidermolysis Bullosa.
0 · Reply
StocktwitsNews
StocktwitsNews Feb. 17 at 8:21 PM
KRYS Stock Rallies On Upbeat Earnings: Jefferies Ups Price Target On Sustained Vyjuvek Optimism $KRYS $IJR $VTI https://stocktwits.com/news/equity/markets/krys-stock-rallies-on-upbeat-earnings-jefferies-ups-price-target/cZRWvWzR4HT
0 · Reply
1GreenDay99RedDays
1GreenDay99RedDays Feb. 17 at 6:57 PM
$KRYS honestly i cant think of a better looking chart in all of biotech than this, i made money here in 2021 and sold like a stunad congrats to all
0 · Reply
GitRichOrBuyTryin
GitRichOrBuyTryin Feb. 17 at 4:52 PM
$KRYS - Bought KRYS at $290 IBD buy point triggered at $286.52
0 · Reply
d_risk
d_risk Feb. 17 at 4:43 PM
$KRYS - Krystal Biotech Inc - 10K - Updated Risk Factors KRYS’s 2026 10-K sharpens risk around VYJUVEK dependence, global gene therapy commercialization and manufacturing scale-up (including ASTRA), intensifies focus on pricing/reimbursement, IP and patent litigation, cybersecurity and a 2024 incident, AI and data privacy laws, while adding detailed global regulatory, quality, executive loss, and capital/ownership concentration risks. #GeneTherapy #ManufacturingScale-Up #PricingRisk #IPLitigation #Cybersecurity 🟢 Added 🟠 Removed https://d-risk.ai/KRYS/10-K/2026-02-17
0 · Reply
OpenOutcrier
OpenOutcrier Feb. 17 at 1:59 PM
$KRYS (-1.2% pre) Krystal Biotech beats top-line and bottom-line estimates; initiates FY26 outlook https://ooc.bz/l/93538
0 · Reply
DonCorleone77
DonCorleone77 Feb. 17 at 12:30 PM
$KRYS Krystal Biotech sees FY26 non-GAAP R&D, SG&A expense $175M-$195M
0 · Reply
DonCorleone77
DonCorleone77 Feb. 17 at 12:29 PM
$KRYS Krystal Biotech reports Q4 EPS $1.70, consensus $1.61 Reports Q4 revenue $107.1M, consensus $105.13M. "In 2025, Krystal made meaningful progress on our mission to serve patients with dystrophic epidermolysis bullosa around the world, while continuing to build the global infrastructure required to scale our impact," said Krish S. Krishnan, Chairman and CEO of Krystal Biotech. "As we work toward our goal of launching multiple products and treating more than 10,000 patients living with rare diseases by the end of 2030, our recent cystic fibrosis readout further reinforces the versatility of our platform in high-turnover epithelial tissues. We believe we are still in the early stages of unlocking the transformational potential of our redosable HSV-1-based gene delivery platform, and we look forward to multiple registrational study readouts ahead across our rare disease pipeline."
0 · Reply
StocktwitsEarnings
StocktwitsEarnings Feb. 17 at 12:13 PM
$KRYS Q4 '25 Earnings Results & Recap • Reported GAAP EPS of $1.77 up 12.03% YoY • Reported revenue of $107.11M up 17.52% YoY • Krystal Biotech, Inc. expects pricing negotiations for VYJUVEK in Germany and France to continue until at least H2 2026 and 2027, respectively, with a potential Italian launch in H2 2026. Krystal Biotech, Inc. also anticipates initiating a Phase 2 study for KB304 in 2027.
0 · Reply
Florestan
Florestan Feb. 17 at 5:50 AM
$MSLE if you're bitter and you're bashing because you missed the boat, guess what? You haven't. A disease modifying drug for DMD would be worth billions. Look at Avidity. Look at Sarepta when the world thought their drug would work. Look at $KRYS, perennial buyout target after having a disease modifying drug for DEB. This is just the beginning for Satellos.
0 · Reply
eWhispers
eWhispers Feb. 16 at 3:33 PM
#earnings before the open on Tuesday, February 17, 2026 https://www.earningswhispers.com/calendar $ET $MDT $LDOS $KRYS $ETOR
1 · Reply