Market Cap 5.25B
Revenue (ttm) 385.69M
Net Income (ttm) -287.22M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -74.47%
Debt to Equity Ratio 3.41
Volume 531,768
Avg Vol 669,734
Day's Range N/A - N/A
Shares Out 49.24M
Stochastic %K 54%
Beta 0.51
Analysts Strong Sell
Price Target $175.67

Company Profile

Axsome Therapeutics, Inc., a biopharmaceutical company, develops and delivers novel therapies for the management of central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist, sigma-1 receptor agonist, aminoketone, and CYP2D6 inhibitor indicated for the treatment of major depressive disorder in adults; Sunosi (solriamfetol), a dopamine and norepinephrine reuptak...

Industry: Biotechnology
Sector: Healthcare
Phone: 212 332 3241
Fax: 212 320 0245
Address:
One World Trade Center, 22nd Floor, New York, United States
jozef56
jozef56 Aug. 6 at 2:02 PM
$AXSM no much big news expected the next 4 till 8 weeks so investers trying their luck with stocks with more volatility. Axsome probably will mostly swing between 95 and 105 but also with some spikes up a downwards. Sell and buy moments.
1 · Reply
pi22dv7
pi22dv7 Aug. 6 at 1:41 PM
$AXSM After a STRONG ER and promising update to the pipeline, stonk gets punished, AXSM never disappoints long term investors. Bull-ish?
0 · Reply
jozef56
jozef56 Aug. 6 at 12:34 PM
$AXSM i like to see a little net profit within 1 year ...must be doable because decrease of r&d projects ...increase in sales...initial sales launches etc etc
1 · Reply
Vakeshka
Vakeshka Aug. 6 at 2:23 AM
$AXSM a new Auvelity review just posted on drugs.com Ano... Taken for 1 to 6 months August 4, 2025 For Major Depressive Disorder "I have never written a medication review. I have tried every other type of medication for depression, and they all made me feel worse or zombie-like. Auvelity started lifting my mood within hours. After about a week, I did experience dissociation, fatigue, and major anxiety. However, I stuck it out because it was the first medication I ever felt major symptom relief from and saw other reviews that they had those bad side effects but stuck it out. Now it has been about a month, and I am the happiest I have ever been. I am motivated, it has helped my ADHD more than stimulants, and I am a way better mom, partner, and friend. I am much less irritable and am happy to wake up every day. I did not believe any medication would help me, but Auvelity has been life-changing and a miracle for me!!"
1 · Reply
Idvst8
Idvst8 Aug. 5 at 6:35 PM
$AXSM - High conviction that these are part of the next Sizeable Buyouts in Bio-land $AXSM, $MDGL, $VKTX I also think Sarepta may do some type of Deal at these Valuations in Fall or Winter. Lastly, Sangamo NEEDS a Deal, and needs Cash badly. Will be interesting what old Sandy comes up with. Quite possibly the Largest destruction of shareholders value to Date, without going fully Tits up . They should get a Deal. Their Pipeline is Deep and Valuable.
1 · Reply
quickaspeter
quickaspeter Aug. 5 at 5:21 PM
$AXSM Axsome Therapeutics Inc. Q2 2025 ER Highlights: Robust Revenue Growth and… https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/axsome-therapeutics-inc-axsm-q2-070903637.html&ct=ga&cd=CAEYACoTNzc1MzY3OTM5MjA5MDEzNTY2MTIaYzZjNTUzMjg1ZThkMTEzYTpjb206ZW46Q0E&usg=AOvVaw2463w7hLEL5kUQuTTRLo5q
0 · Reply
ZacksResearch
ZacksResearch Aug. 5 at 4:58 PM
$AXSM Q2 loss beats expectations — but the real story is revenue 🚀 Auvelity sales fueled a 72% year-over-year revenue jump, powering a much narrower quarterly loss. Full earnings breakdown here 👉 https://www.zacks.com/stock/news/2668227/axsm-q2-loss-narrower-than-expected-auvelity-drives-revenues-yy?cid=sm-stocktwits-2-2668227-teaser-6120&ADID=SYND_STOCKTWITS_TWEET_2_2668227_TEASER_6120
0 · Reply
ZacksResearch
ZacksResearch Aug. 5 at 3:22 PM
$AXSM rallies 25.9% YTD — what’s driving the momentum? 🚀 💊 Q2 revenue surged 72% YoY in Q2, beating estimates thanks to strong Auvelity sales for MDD. 📈 Auvelity sales jumped 84% YoY in Q2, with prescriptions up 56%. Discover what’s fueling this growth story 👉 https://www.zacks.com/stock/news/2668227/axsm-q2-loss-narrower-than-expected-auvelity-drives-revenues-yy?cid=sm-stocktwits-2-2668227-body-6026&ADID=SYND_STOCKTWITS_TWEET_2_2668227_BODY_6026
0 · Reply
BiotechBonesaw
BiotechBonesaw Aug. 5 at 2:52 PM
$BTAI has competition from $AXSM $ACAD Otsuka and many other biotechs. Again I hope you all help patients but comparing this to $TNXP - which literally has no near-term competition in the fibromyalgia space - doesn’t seem appropriate. 🤷‍♂️
0 · Reply
Uncle_Baby_Billy
Uncle_Baby_Billy Aug. 5 at 2:31 PM
$AXSM Damn…..would hate to see what happens with a downgrade🤔
1 · Reply
Latest News on AXSM
Axsome: Some Recent Setbacks, Some Recent Wins -- Still A Buy

Jul 25, 2025, 1:46 PM EDT - 12 days ago

Axsome: Some Recent Setbacks, Some Recent Wins -- Still A Buy


Axsome Therapeutics Clocks Around 60% Topline Growth In Q1

May 5, 2025, 10:41 AM EDT - 3 months ago

Axsome Therapeutics Clocks Around 60% Topline Growth In Q1


Axsome: The Alzheimer's Agitation Program For AXS-05

Mar 21, 2025, 11:36 AM EDT - 4 months ago

Axsome: The Alzheimer's Agitation Program For AXS-05


Axsome Q4 Earnings: Revenues Rising, Skepticism Lingering

Feb 20, 2025, 8:15 AM EST - 5 months ago

Axsome Q4 Earnings: Revenues Rising, Skepticism Lingering


Axsome Therapeutics, Inc. (AXSM) Q4 2024 Earnings Call Transcript

Feb 18, 2025, 11:12 AM EST - 6 months ago

Axsome Therapeutics, Inc. (AXSM) Q4 2024 Earnings Call Transcript


US FDA approves Axsome Therapeutics' migraine drug

Jan 30, 2025, 3:55 PM EST - 6 months ago

US FDA approves Axsome Therapeutics' migraine drug


Axsome Therapeutics Remains A Buy Despite AXS-05's Mixed Results

Dec 31, 2024, 9:15 AM EST - 7 months ago

Axsome Therapeutics Remains A Buy Despite AXS-05's Mixed Results


Axsome Therapeutics: Lots Of Moving Parts

Jul 23, 2024, 4:06 AM EDT - 1 year ago

Axsome Therapeutics: Lots Of Moving Parts


jozef56
jozef56 Aug. 6 at 2:02 PM
$AXSM no much big news expected the next 4 till 8 weeks so investers trying their luck with stocks with more volatility. Axsome probably will mostly swing between 95 and 105 but also with some spikes up a downwards. Sell and buy moments.
1 · Reply
pi22dv7
pi22dv7 Aug. 6 at 1:41 PM
$AXSM After a STRONG ER and promising update to the pipeline, stonk gets punished, AXSM never disappoints long term investors. Bull-ish?
0 · Reply
jozef56
jozef56 Aug. 6 at 12:34 PM
$AXSM i like to see a little net profit within 1 year ...must be doable because decrease of r&d projects ...increase in sales...initial sales launches etc etc
1 · Reply
Vakeshka
Vakeshka Aug. 6 at 2:23 AM
$AXSM a new Auvelity review just posted on drugs.com Ano... Taken for 1 to 6 months August 4, 2025 For Major Depressive Disorder "I have never written a medication review. I have tried every other type of medication for depression, and they all made me feel worse or zombie-like. Auvelity started lifting my mood within hours. After about a week, I did experience dissociation, fatigue, and major anxiety. However, I stuck it out because it was the first medication I ever felt major symptom relief from and saw other reviews that they had those bad side effects but stuck it out. Now it has been about a month, and I am the happiest I have ever been. I am motivated, it has helped my ADHD more than stimulants, and I am a way better mom, partner, and friend. I am much less irritable and am happy to wake up every day. I did not believe any medication would help me, but Auvelity has been life-changing and a miracle for me!!"
1 · Reply
Idvst8
Idvst8 Aug. 5 at 6:35 PM
$AXSM - High conviction that these are part of the next Sizeable Buyouts in Bio-land $AXSM, $MDGL, $VKTX I also think Sarepta may do some type of Deal at these Valuations in Fall or Winter. Lastly, Sangamo NEEDS a Deal, and needs Cash badly. Will be interesting what old Sandy comes up with. Quite possibly the Largest destruction of shareholders value to Date, without going fully Tits up . They should get a Deal. Their Pipeline is Deep and Valuable.
1 · Reply
quickaspeter
quickaspeter Aug. 5 at 5:21 PM
$AXSM Axsome Therapeutics Inc. Q2 2025 ER Highlights: Robust Revenue Growth and… https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/axsome-therapeutics-inc-axsm-q2-070903637.html&ct=ga&cd=CAEYACoTNzc1MzY3OTM5MjA5MDEzNTY2MTIaYzZjNTUzMjg1ZThkMTEzYTpjb206ZW46Q0E&usg=AOvVaw2463w7hLEL5kUQuTTRLo5q
0 · Reply
ZacksResearch
ZacksResearch Aug. 5 at 4:58 PM
$AXSM Q2 loss beats expectations — but the real story is revenue 🚀 Auvelity sales fueled a 72% year-over-year revenue jump, powering a much narrower quarterly loss. Full earnings breakdown here 👉 https://www.zacks.com/stock/news/2668227/axsm-q2-loss-narrower-than-expected-auvelity-drives-revenues-yy?cid=sm-stocktwits-2-2668227-teaser-6120&ADID=SYND_STOCKTWITS_TWEET_2_2668227_TEASER_6120
0 · Reply
ZacksResearch
ZacksResearch Aug. 5 at 3:22 PM
$AXSM rallies 25.9% YTD — what’s driving the momentum? 🚀 💊 Q2 revenue surged 72% YoY in Q2, beating estimates thanks to strong Auvelity sales for MDD. 📈 Auvelity sales jumped 84% YoY in Q2, with prescriptions up 56%. Discover what’s fueling this growth story 👉 https://www.zacks.com/stock/news/2668227/axsm-q2-loss-narrower-than-expected-auvelity-drives-revenues-yy?cid=sm-stocktwits-2-2668227-body-6026&ADID=SYND_STOCKTWITS_TWEET_2_2668227_BODY_6026
0 · Reply
BiotechBonesaw
BiotechBonesaw Aug. 5 at 2:52 PM
$BTAI has competition from $AXSM $ACAD Otsuka and many other biotechs. Again I hope you all help patients but comparing this to $TNXP - which literally has no near-term competition in the fibromyalgia space - doesn’t seem appropriate. 🤷‍♂️
0 · Reply
Uncle_Baby_Billy
Uncle_Baby_Billy Aug. 5 at 2:31 PM
$AXSM Damn…..would hate to see what happens with a downgrade🤔
1 · Reply
quickaspeter
quickaspeter Aug. 5 at 2:22 PM
$AXSM Alright, alright, alright…now, let’s go! 💥🚀💰
1 · Reply
ChappiesWorld
ChappiesWorld Aug. 5 at 2:20 PM
$AXSM obviously we are in a holding pattern between $100-$108 until the Alzheimer's Agitation filing gets accepted or rejected by the FDA. The issue seems to be, if we get a positive outcome, we might get a 5-10% bump. BUT if its rejected or delayed...who knows how far we drop.
1 · Reply
jeremytowe2000
jeremytowe2000 Aug. 5 at 2:19 PM
$AXSM $TGTX Best wishes to all BIO lovers and longs here. I have ended my BIO sector investment adventure officially. Whatever small investment I had left in BIO, I cleared all yesterday. Again best wishes. While I won't be in BIO, I do wish both these stocks reach to much higher.
9 · Reply
pi22dv7
pi22dv7 Aug. 5 at 1:41 PM
$AXSM All these analysts should keep quiet :-), these raises means nothing to AXSM PPS, what’s the point of this?
2 · Reply
Vakeshka
Vakeshka Aug. 5 at 1:40 PM
$AXSM RBC raises PT to $189 from $184, keeps Outperform rating.
0 · Reply
Vakeshka
Vakeshka Aug. 5 at 12:26 PM
$AXSM "Bank of America has increased its price target for Axsome Therapeutics from $173 to $176, maintaining a Buy rating for the stock. This decision comes in light of the company's strong performance in the second quarter, with revenues outperforming expectations due to solid sales of Auvelity and Sunosi. The bank's analysts believe that the full potential of Auvelity across various indications is not fully recognized in the market..."
0 · Reply
Vakeshka
Vakeshka Aug. 5 at 9:46 AM
$AXSM Cerena Chen from Wells Fargo maintained a Buy rating on Axsome Therapeutics, with a price target of $165.00
0 · Reply
Vakeshka
Vakeshka Aug. 5 at 9:45 AM
$AXSM "...Axsome Therapeutics Inc (AXSM, Financial) demonstrates significant strengths in its expanding product portfolio and strategic partnerships, which are key drivers of its revenue growth. However, the company faces challenges in managing its financial performance and net losses. Opportunities for growth are abundant in the burgeoning CNS market, but Axsome must also contend with competitive threats and regulatory challenges. By leveraging its strengths and addressing its weaknesses, Axsome can capitalize on opportunities and mitigate threats, positioning itself for long-term success in the CNS therapeutic space... https://www.gurufocus.com/news/3033519/decoding-axsome-therapeutics-inc-axsm-a-strategic-swot-insight?r=4bf001661e6fdd88d0cd7a5659ff9748&mod=mw_quote_news
0 · Reply
Mike826_1999
Mike826_1999 Aug. 5 at 9:37 AM
$AXSM Three key dimensions of how “smart money” is positioned in Axsome and the broader health-care hedge fund universe: 1. Active vs Passive Institutional Ownership of AXSM. 70.1%** of Axsome’s institutional holders are **active managers** (i.e. they pick stocks, rather than just track an index). * Historically, that’s sat between **54%** (low) and **99%** (high) — so Axsome today is in the **lower‐middle** of its active-manager ownership range. 2. Hedge-Fund “Long/Short” & Net-Exposure in Health Care. Long/Short Ratio** (long exposure ÷ short exposure) in health care has been as low as \~1.4x and as high as \~2.6x over the last decade. * Today it’s around **2.2x**, **above** its long-term median (\~2.0x) but off the peak seen in 2021–22. * **Net Exposure** (health-care weight as a % of total net hedge-fund positions) has ranged from \~8% to \~26%. * Currently it sits near **19%**, **above** its long-run median (\~15%), reflecting an overall **overweight** stance in the sector. Continued
1 · Reply
Mike826_1999
Mike826_1999 Aug. 5 at 9:19 AM
$AXSM According to Morgan Stanley’s August 4, 2025 research note on Axsome Therapeutics, their positive and negative views break down roughly as follows: Positive Highlights Auvelity launch execution Auvelity generated $120 M in 2Q 2025 sales, coming in ~8% above Morgan Stanley’s $115 M estimate (and 8% above consensus) and delivering 24% quarter-over-quarter growth. Broad CNS pipeline momentum “Axsome is progressing multiple programs as part of a broad CNS pipeline,” with near-term catalysts (e.g., Alzheimer’s agitation sNDA, pivotal trials in smoking cessation and fibromyalgia) that could “present upside surprises to the market’s current expectations.” Regulatory progress The sNDA filing for AXS-05 in Alzheimer’s disease agitation is on-track for 3Q 2025, an event Morgan Stanley views as a significant value inflection. Strong cash runway Axsome exited 2Q 2025 with ~$303 M in cash and equivalents, “sufficient to fund operations into cash-flow positivity.” Continued
1 · Reply
RickSanders9
RickSanders9 Aug. 5 at 2:17 AM
$AXSM 3 qtr's ago, HT used verbiage indicating active interest in the possibility of an EX-Us partnership. I don't work in the field, but you'd think one analyst would inquire about it, in-place of their lazy, layup question. "Hi, this is Mike/Jlfrom from STwits Investments. Has there been an movement or progess on an international partnership?" Give it some thought, fellas....
3 · Reply
Vakeshka
Vakeshka Aug. 5 at 1:29 AM
$AXSM Bank of America Securities analyst Jason Gerberry has reiterated their bullish stance on AXSM stock, giving a Buy rating...due to a combination of factors including Axsome Therapeutics’ strong financial performance and growth potential. The company’s second-quarter earnings per share exceeded expectations, driven by better-than-anticipated results from Auvelity and Sunosi. This success has led to an increase in forecasts for Auvelity’s major depressive disorder (MDD) treatment, with expectations of continued prescription growth supported by favorable payer contracting. Additionally, while Symbravo’s initial revenues were modest, this was anticipated due to its recent market entry. The focus on targeted headache centers is expected to enhance its performance over time. Furthermore, Auvelity’s expanding presence in the primary care segment, along with increased payer coverage, positions it well for future growth...
0 · Reply