Market Cap 2.11B
Revenue (ttm) 0.00
Net Income (ttm) -175.85M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 10.43
Profit Margin 0.00%
Debt to Equity Ratio 0.10
Volume 360,212
Avg Vol 1,493,774
Day's Range N/A - N/A
Shares Out 53.71M
Stochastic %K 52%
Beta -3.16
Analysts Strong Sell
Price Target $112.08

Company Profile

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is Diazoxide Choline Extended-Release tablets, a once-daily oral tablet which is in Phase III clinical trials for the treatment of Prader-Willi Syndrome. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was i...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 213 8444
Fax: 650 213 8383
Website: soleno.life
Address:
100 Marine Parkway, Suite 400, Redwood City, United States
UgoGreg
UgoGreg Feb. 21 at 5:10 PM
$SLNO https://youtu.be/ygBN8MilTyc
0 · Reply
Tdorsey1776
Tdorsey1776 Feb. 20 at 3:26 PM
$SLNO Added 1k @ $38.175, probably done buying down here
0 · Reply
Tdorsey1776
Tdorsey1776 Feb. 19 at 5:16 PM
$SLNO Getting ready to turn higher as its bottoming. Risk/reward very favorable, added 1k. 2026 should see massive outperformance. GLTA
1 · Reply
Neptune187
Neptune187 Feb. 19 at 8:15 AM
$SLNO Green today
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 18 at 11:23 AM
$SLNO RSI: 39.37, MACD: -1.6997 Vol: 2.02, MA20: 41.27, MA50: 44.87 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Feb. 14 at 4:02 AM
The attachment compares $SLNO analyst consensus revenue estimates to 6 peers with similar revenue dollar projections that exited via M&A. Analysts forecast SLNO to generate more revenues, and at higher gross margins, than 5 of the 6. All were acquired at meaningfully higher Year 4 & 10-year multiples. $FOLD projected 10-year revenues 1/3 less than analysts forecast for SLNO yet was acquired for 2.2X higher than SLNO's market cap. SLNO has roughly $500MM cash. If the table used SLNO's enterprise value the multiples would be 25% lower. SLNO management & BOD need to seriously consider an M&A exit if their valuation continues to be materially lower than these peers. $XBI $IBB
1 · Reply
Biocontrol
Biocontrol Feb. 12 at 4:59 PM
$SLNO Guggenheim call was good, imo. Discontinuation rate maturing around 15%. Titration - patients are taking prescribed doses, average wac in low $500K due to slight older pt/higher weight than originally projected. Reach - over 600 prescribers now, more than expected. Reimbursement - good payers in Medicaid and part D, and all new to market blocks removed from big PBMs. Europe - Tending toward GIA in Europe as they’ve been building that staff. Future - Looking at new asset opportunities as they’ve come along, but likely nothing the short term. Looking at new indications for Vykat, with more info to come soon.
2 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Feb. 11 at 9:29 PM
$NBIX reported $135.3MM in Crenecessity sales in its 4th full quarter on the market (Q42025). Crenecessity sales dollars by quarter since launch have been consistent with VRNA & $IMGN product launches (both acquired for ~$10B) as well as $MDGL Rezdiffra, as outlined on the attached graph. MDGL's market cap is ~$11B (before meaningful dilution). If new drugs are worth some multiple of projected sales, and Crenecessity sales are consistent with those sold for $10B then is it possible NBIX is a value at an enterprise value of roughly $11B? NBIX sales on the attachment do not consider Ingrezza FY2025 sales of $2.8B. This is not investment advice. It appears NBIX projects flat Ingrezza sales in FY2026. The graph also notes $SLNO Vykat sales for its first 3 quarters on the market (released weeks ago) for perspective. $XBI
0 · Reply
haha1978
haha1978 Feb. 9 at 7:13 PM
$SLNO https://investors.soleno.life/news-releases/news-release-details/soleno-therapeutics-announces-submission-and-ema-validation#:~:text=The%20Company%20has%20been%20granted,XR%20on%20March%2026%2C%202025%20.
1 · Reply
haha1978
haha1978 Feb. 6 at 3:56 PM
$SLNO EMA approval decision is within the 1st Half of 2026. Could be this month.
1 · Reply
Latest News on SLNO
Soleno Therapeutics, Inc. Investigated by the Portnoy Law Firm

Nov 12, 2025, 10:56 AM EST - 3 months ago

Soleno Therapeutics, Inc. Investigated by the Portnoy Law Firm


Soleno: Blockbuster Launch In Progress

Oct 11, 2025, 8:45 AM EDT - 4 months ago

Soleno: Blockbuster Launch In Progress


Soleno Therapeutics, Inc. (SLNO) Q1 2025 Earnings Call Transcript

May 7, 2025, 10:30 PM EDT - 10 months ago

Soleno Therapeutics, Inc. (SLNO) Q1 2025 Earnings Call Transcript


Soleno Therapeutics Announces VYKAT(TM) XR Launch

Apr 14, 2025, 7:00 AM EDT - 11 months ago

Soleno Therapeutics Announces VYKAT(TM) XR Launch


UgoGreg
UgoGreg Feb. 21 at 5:10 PM
$SLNO https://youtu.be/ygBN8MilTyc
0 · Reply
Tdorsey1776
Tdorsey1776 Feb. 20 at 3:26 PM
$SLNO Added 1k @ $38.175, probably done buying down here
0 · Reply
Tdorsey1776
Tdorsey1776 Feb. 19 at 5:16 PM
$SLNO Getting ready to turn higher as its bottoming. Risk/reward very favorable, added 1k. 2026 should see massive outperformance. GLTA
1 · Reply
Neptune187
Neptune187 Feb. 19 at 8:15 AM
$SLNO Green today
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 18 at 11:23 AM
$SLNO RSI: 39.37, MACD: -1.6997 Vol: 2.02, MA20: 41.27, MA50: 44.87 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Feb. 14 at 4:02 AM
The attachment compares $SLNO analyst consensus revenue estimates to 6 peers with similar revenue dollar projections that exited via M&A. Analysts forecast SLNO to generate more revenues, and at higher gross margins, than 5 of the 6. All were acquired at meaningfully higher Year 4 & 10-year multiples. $FOLD projected 10-year revenues 1/3 less than analysts forecast for SLNO yet was acquired for 2.2X higher than SLNO's market cap. SLNO has roughly $500MM cash. If the table used SLNO's enterprise value the multiples would be 25% lower. SLNO management & BOD need to seriously consider an M&A exit if their valuation continues to be materially lower than these peers. $XBI $IBB
1 · Reply
Biocontrol
Biocontrol Feb. 12 at 4:59 PM
$SLNO Guggenheim call was good, imo. Discontinuation rate maturing around 15%. Titration - patients are taking prescribed doses, average wac in low $500K due to slight older pt/higher weight than originally projected. Reach - over 600 prescribers now, more than expected. Reimbursement - good payers in Medicaid and part D, and all new to market blocks removed from big PBMs. Europe - Tending toward GIA in Europe as they’ve been building that staff. Future - Looking at new asset opportunities as they’ve come along, but likely nothing the short term. Looking at new indications for Vykat, with more info to come soon.
2 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Feb. 11 at 9:29 PM
$NBIX reported $135.3MM in Crenecessity sales in its 4th full quarter on the market (Q42025). Crenecessity sales dollars by quarter since launch have been consistent with VRNA & $IMGN product launches (both acquired for ~$10B) as well as $MDGL Rezdiffra, as outlined on the attached graph. MDGL's market cap is ~$11B (before meaningful dilution). If new drugs are worth some multiple of projected sales, and Crenecessity sales are consistent with those sold for $10B then is it possible NBIX is a value at an enterprise value of roughly $11B? NBIX sales on the attachment do not consider Ingrezza FY2025 sales of $2.8B. This is not investment advice. It appears NBIX projects flat Ingrezza sales in FY2026. The graph also notes $SLNO Vykat sales for its first 3 quarters on the market (released weeks ago) for perspective. $XBI
0 · Reply
haha1978
haha1978 Feb. 9 at 7:13 PM
$SLNO https://investors.soleno.life/news-releases/news-release-details/soleno-therapeutics-announces-submission-and-ema-validation#:~:text=The%20Company%20has%20been%20granted,XR%20on%20March%2026%2C%202025%20.
1 · Reply
haha1978
haha1978 Feb. 6 at 3:56 PM
$SLNO EMA approval decision is within the 1st Half of 2026. Could be this month.
1 · Reply
CH_Expat
CH_Expat Feb. 4 at 7:05 PM
$SLNO For transparency, I sold yesterday plusminus 0. Need to raise cash as I think the bio correction is in full flow. Will watch this one very carefully. Good luck guys.
0 · Reply
MaxKlim
MaxKlim Feb. 4 at 6:39 PM
$SLNO double profit !!!
0 · Reply
MaxKlim
MaxKlim Feb. 4 at 6:38 PM
$SLNO in the process of share buyback maybe they will announce an additional volume of 100 mm?
0 · Reply
VertexVault
VertexVault Feb. 4 at 9:52 AM
$SLNO biotech, clinical-stage pipeline
0 · Reply
JFais
JFais Feb. 3 at 11:29 PM
Only Tuesday and already some good discussions cooking in Chat: -How does $NKTR benefit from OX-40 failures, potential to take a slice of 1st line too? -More points made on $SLNO after my blog post, reminder it's trading at only 10x earning with 100% growth! -In non-bio channel $CEPT & other tokenization plays
0 · Reply
JFais
JFais Jan. 31 at 10:02 PM
$SLNO - Across The Biotech Universe: Soleno Therapeutics https://seekingalpha.com/instablog/440063-jonathan-faison/6254732-across-the-biotech-universe-slno?share_source=shared_news?source=tweet
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 30 at 10:03 PM
Year 4 & 10-Year revenue multiples of all commercial-stage non-oncology focused bios as of 1/30/26 (for those with analyst revenue estimates thru FY2034) with market caps of $1.0B to $5.5B. $PHAT trades at the lowest Year 4 multiple because, among other reasons, its Voquezna patent expires in May 2032 where most (but not all like $HRMY) peers on this list have longer IP runways. $SLNO to us is a head scratcher after reporting roughly $90MM in Q425 Vykat product sales. This was its 3rd full fiscal quarter on the market (outselling names like GWPH's Epidiolex & Verona's Ohtuvayre). SLNO's revenue multiple does not consider its cash at 25% of its market cap. It would be appreciated if anyone can comment on SLNO's risk v reward profile. $ARDX did have an FY34 patent expiration for its API that was recently extended through FY2041. $MIRM is the best performing stock in this peer group (since /2025. This is not investment advice. We're simply sharing our analysis.
5 · Reply
elmono
elmono Jan. 30 at 3:44 PM
$SLNO trades like we gonna see patient deaths or whatever 🤷‍♂️
2 · Reply
Merlintrader
Merlintrader Jan. 29 at 6:36 PM
$SLNO https://www.merlintrader.com/aard-aardvark-therapeutics-inc/
0 · Reply
JFais
JFais Jan. 29 at 2:28 PM
$SLNO- one of those names I'd love to see bought out, simply b/c so many bears & people that hate the drug (good for $XBI, remind shorts the r/r isn't there)
0 · Reply
Baldchinese
Baldchinese Jan. 28 at 6:21 PM
$SLNO this stock is such a dog man 😞
0 · Reply
Quantumup
Quantumup Jan. 28 at 3:44 PM
B Riley🏁 $AARD at a Buy rating and a $32 PT. $SLNO $RYTM Here's what B Riley had to say in its Aardvark Therapeutics Inc. initiation report: https://x.com/Quantumup1/status/2016536884109816169?s=20
0 · Reply