Market Cap 2.07B
Revenue (ttm) 0.00
Net Income (ttm) -175.85M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 10.49
Profit Margin 0.00%
Debt to Equity Ratio 0.10
Volume 2,469,200
Avg Vol 1,561,356
Day's Range N/A - N/A
Shares Out 53.71M
Stochastic %K 67%
Beta -3.12
Analysts Strong Sell
Price Target $112.08

Company Profile

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is Diazoxide Choline Extended-Release tablets, a once-daily oral tablet which is in Phase III clinical trials for the treatment of Prader-Willi Syndrome. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was i...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 213 8444
Fax: 650 213 8383
Website: soleno.life
Address:
100 Marine Parkway, Suite 400, Redwood City, United States
JFais
JFais Jan. 31 at 10:02 PM
$SLNO - Across The Biotech Universe: Soleno Therapeutics https://seekingalpha.com/instablog/440063-jonathan-faison/6254732-across-the-biotech-universe-slno?share_source=shared_news?source=tweet
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 30 at 10:03 PM
Year 4 & 10-Year revenue multiples of all commercial-stage non-oncology focused bios as of 1/30/26 (for those with analyst revenue estimates thru FY2034) with market caps of $1.0B to $5.5B. $PHAT trades at the lowest Year 4 multiple because, among other reasons, its Voquezna patent expires in May 2032 where most (but not all like $HRMY) peers on this list have longer IP runways. $SLNO to us is a head scratcher after reporting roughly $90MM in Q425 Vykat product sales. This was its 3rd full fiscal quarter on the market (outselling names like GWPH's Epidiolex & Verona's Ohtuvayre). SLNO's revenue multiple does not consider its cash at 25% of its market cap. It would be appreciated if anyone can comment on SLNO's risk v reward profile. $ARDX did have an FY34 patent expiration for its API that was recently extended through FY2041. $MIRM is the best performing stock in this peer group (since /2025. This is not investment advice. We're simply sharing our analysis.
3 · Reply
elmono
elmono Jan. 30 at 3:44 PM
$SLNO trades like we gonna see patient deaths or whatever 🤷‍♂️
2 · Reply
Merlintrader
Merlintrader Jan. 29 at 6:36 PM
$SLNO https://www.merlintrader.com/aard-aardvark-therapeutics-inc/
0 · Reply
JFais
JFais Jan. 29 at 2:28 PM
$SLNO- one of those names I'd love to see bought out, simply b/c so many bears & people that hate the drug (good for $XBI, remind shorts the r/r isn't there)
0 · Reply
Baldchinese
Baldchinese Jan. 28 at 6:21 PM
$SLNO this stock is such a dog man 😞
0 · Reply
Quantumup
Quantumup Jan. 28 at 3:44 PM
B Riley🏁 $AARD at a Buy rating and a $32 PT. $SLNO $RYTM Here's what B Riley had to say in its Aardvark Therapeutics Inc. initiation report: https://x.com/Quantumup1/status/2016536884109816169?s=20
0 · Reply
Bafiouski
Bafiouski Jan. 26 at 7:48 PM
$SLNO how come this isnt trading higher
0 · Reply
RandomInvestor777
RandomInvestor777 Jan. 24 at 2:29 PM
$SLNO new 8k. Buyout soon? 100-150% upside is locked in
1 · Reply
Grouphome
Grouphome Jan. 22 at 11:37 PM
$SLNO probably a decent spot
0 · Reply
Latest News on SLNO
Soleno Therapeutics, Inc. Investigated by the Portnoy Law Firm

Nov 12, 2025, 10:56 AM EST - 2 months ago

Soleno Therapeutics, Inc. Investigated by the Portnoy Law Firm


Soleno: Blockbuster Launch In Progress

Oct 11, 2025, 8:45 AM EDT - 4 months ago

Soleno: Blockbuster Launch In Progress


Soleno Therapeutics Announces VYKAT(TM) XR Launch

Apr 14, 2025, 7:00 AM EDT - 10 months ago

Soleno Therapeutics Announces VYKAT(TM) XR Launch


JFais
JFais Jan. 31 at 10:02 PM
$SLNO - Across The Biotech Universe: Soleno Therapeutics https://seekingalpha.com/instablog/440063-jonathan-faison/6254732-across-the-biotech-universe-slno?share_source=shared_news?source=tweet
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 30 at 10:03 PM
Year 4 & 10-Year revenue multiples of all commercial-stage non-oncology focused bios as of 1/30/26 (for those with analyst revenue estimates thru FY2034) with market caps of $1.0B to $5.5B. $PHAT trades at the lowest Year 4 multiple because, among other reasons, its Voquezna patent expires in May 2032 where most (but not all like $HRMY) peers on this list have longer IP runways. $SLNO to us is a head scratcher after reporting roughly $90MM in Q425 Vykat product sales. This was its 3rd full fiscal quarter on the market (outselling names like GWPH's Epidiolex & Verona's Ohtuvayre). SLNO's revenue multiple does not consider its cash at 25% of its market cap. It would be appreciated if anyone can comment on SLNO's risk v reward profile. $ARDX did have an FY34 patent expiration for its API that was recently extended through FY2041. $MIRM is the best performing stock in this peer group (since /2025. This is not investment advice. We're simply sharing our analysis.
3 · Reply
elmono
elmono Jan. 30 at 3:44 PM
$SLNO trades like we gonna see patient deaths or whatever 🤷‍♂️
2 · Reply
Merlintrader
Merlintrader Jan. 29 at 6:36 PM
$SLNO https://www.merlintrader.com/aard-aardvark-therapeutics-inc/
0 · Reply
JFais
JFais Jan. 29 at 2:28 PM
$SLNO- one of those names I'd love to see bought out, simply b/c so many bears & people that hate the drug (good for $XBI, remind shorts the r/r isn't there)
0 · Reply
Baldchinese
Baldchinese Jan. 28 at 6:21 PM
$SLNO this stock is such a dog man 😞
0 · Reply
Quantumup
Quantumup Jan. 28 at 3:44 PM
B Riley🏁 $AARD at a Buy rating and a $32 PT. $SLNO $RYTM Here's what B Riley had to say in its Aardvark Therapeutics Inc. initiation report: https://x.com/Quantumup1/status/2016536884109816169?s=20
0 · Reply
Bafiouski
Bafiouski Jan. 26 at 7:48 PM
$SLNO how come this isnt trading higher
0 · Reply
RandomInvestor777
RandomInvestor777 Jan. 24 at 2:29 PM
$SLNO new 8k. Buyout soon? 100-150% upside is locked in
1 · Reply
Grouphome
Grouphome Jan. 22 at 11:37 PM
$SLNO probably a decent spot
0 · Reply
Biocontrol
Biocontrol Jan. 22 at 3:06 PM
$SLNO I buy 100 shares a day of this. I don’t know why, but maybe someday I will.
0 · Reply
Quantumup
Quantumup Jan. 20 at 12:47 PM
H.C. Wainwright⬆️ $SLNO's PT to $120 from $110 aand reiterated at Buy $RYTM $AARD $BIIB Here's what H.C. Wainwright said in its note: https://x.com/Quantumup1/status/2013593295755088257?s=20
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Jan. 19 at 7:42 PM
$SLNO RSI: 31.47, MACD: -2.1528 Vol: 2.68, MA20: 45.64, MA50: 47.44 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 17 at 10:48 PM
$SLNO reported Q425 Vykat sales of ~$92MM. The table compares SLNO Vykat sales by quarter post launch v 3 peer comm'l-stage bios acquired with like sales profiles post launch. The 3 peers were acquired at multiples of actual sales ~4X higher than SLNO trades as an independent. SLNO's 9/30/25 net cash/debt is ~22% of its MC. Put simplest, SLNO needs to consider selling the company to maximize shareholder value if Vykat's value proposition is consistent with the 3 peers. $RYTM & $AARD are developing PWS therapies. ​$NBIX did not disclose Crinessity Q4 2025 product sales at JPM. Crinessity product sales, by themselves, are consistent with the 3 products acquired. NBIX's Ingrezza is on track to reporting $2.5B in FY25 sales (not considered in the multiples noted). $MDGL 's Rexdiffra has been on the market for 6 quarters. MDGL's multiples do not consider material dilutive securities. MDGL posted here for reference only Actual sales do not consider potential TAM. This is not investment advice.
4 · Reply
SuperGreenToday
SuperGreenToday Jan. 16 at 9:11 PM
$SLNO Share Price: $42.47 Contract Selected: Jun 18, 2026 $45 Calls Buy Zone: $6.29 – $7.77 Target Zone: $11.27 – $13.78 Potential Upside: 69% ROI Time to Expiration: 152 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 16 at 6:09 PM
$BCRX trades @ one of the lowest multiples of projected sales of all peer comm'l-stage non-oncology focused bios w/MCs ranging from $1 to $5B. The odds are BCRX shareholders are best served via M&A exit (just like virtually all smaller cap comm'l-stage bios). Is this due to the Astria acquisition? Drugs like Orladeyo are worth some multiple or NPV of the drug's projected sales. While perhaps slower than initially expected, Orladeyo generates meaningful product sales & is patent protected through FY39. $PHAT & $ARDX trade @ BCRX like multiples but both have drugs with patents expiring within 10 years. $SLNO trades at, literally, the lowest multiple of projected sales of all bios in this peer group. SLNO Vykat sales are exceeding VRNA's sales post launch. VRNA was just acquired for an EV of just under $10B. RYTM & AARD are developing pws drugs $LGND trades @ the highest multiples NOTE: The attachment excludes those bios that do not have analyst coverage past FY33 This is for info purposes only
3 · Reply
RunnerSignals
RunnerSignals Jan. 15 at 4:32 AM
Daily Market Pulse Alert $AMCR $CL $ADBE $SLNO $BTDR are flashing key technical signals. Momentum or mean reversion next? https://stocksrunner.com/news/2026-01-14-daily-market-pulse
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JFais
JFais Jan. 14 at 4:52 PM
Only Wednesday and week's idea share/discussions covering quite a few tickers: $TGTX- suggestion subQ Briumvi not included in current valuation $QURE- summary from EHDN Europe webinar $HELP- could it be bigger than Spravato? $SLNO- more ppl warming up to on current weakness
0 · Reply
outlawinvestor1
outlawinvestor1 Jan. 14 at 12:42 PM
$SLNO fair valuation now? 🤔 $ACAD $HRMY $RYTM
1 · Reply
outlawinvestor1
outlawinvestor1 Jan. 14 at 12:25 PM
0 · Reply
VanRamirez937
VanRamirez937 Jan. 13 at 5:52 PM
$SLNO $AMT Strong infrastructure angle
0 · Reply
BioTechHealthX
BioTechHealthX Jan. 13 at 4:55 PM
$SLNO Soleno Therapeutics Inc (NASDAQ:SLNO) is focused on precision therapies for rare diseases. This article explains why SLNO’s long-term story might be more important than it looks. https://biotechhealthx.com/biotech-news/soleno-therapeutics-slno-might-be-building-something-bigger-than-most-investors-realize/
0 · Reply