Market Cap 878.01M
Revenue (ttm) 76.30M
Net Income (ttm) -122.70M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -160.81%
Debt to Equity Ratio 0.00
Volume 765,837
Avg Vol 449,956
Day's Range N/A - N/A
Shares Out 69.68M
Stochastic %K 13%
Beta 1.26
Analysts Strong Sell
Price Target $21.35

Company Profile

Zymeworks Inc., a clinical-stage biotechnology company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer, and autoimmune and inflammatory diseases (AIID). Its therapeutic platforms and fully integrated drug development engine provides the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. The company's platforms include Azymetric multispecific antibody platform; Drug Conjugate platform in...

Industry: Biotechnology
Sector: Healthcare
Phone: 302 274 8744
Address:
108 Patriot Drive, Suite A, Middletown, United States
jimmythetulip
jimmythetulip Aug. 6 at 2:51 PM
$ZYME this stock just doesn’t seem to make any sense…
0 · Reply
twogloves
twogloves Aug. 6 at 2:22 PM
$ZYME big money buying 9/19 15c at the ask 👀👀
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Aug. 5 at 8:41 PM
$ZYME no delays announced by JAZZ again, phase 3 data expected 4th q
0 · Reply
ChessGM
ChessGM Aug. 2 at 6:43 PM
$ZYME "Heads up alert! Upcoming earnings on Thursday, 8/7/2025 for $ZYME Neutral (5.2) --- Detailed Financial Analysis: Zymeworks Inc. (NASDAQ: ZYME) is a clinical-stage biotechnology company focused on the development of multifunctional biotherapeutics. Recent strategic moves, such as the FDA clearance of ZW251, a novel glypican 3-targeted topoisomerase 1 inhibitor, highlight Zymeworks' potential to advance in the oncology space, particularly in hepatocellular carcinoma. Despite the promising pipeline, the stock's recent 7.1% surge may not indicate sustained momentum, as reflected by the lack of significant earnings estimate revisions. On a quantitative front, Zymeworks operates as a high-risk, high-reward entity typical of pre-revenue biotech firms. The company's P/E ratio is not applicable due to its unprofitable status, which is common in the sector as companies focus heavily on R&D rather than immediate profitability. Key financial metrics to watch include revenue forecasts tied to successful drug development and partnerships. While EPS growth remains negative, the company's cash reserves and strategic partnerships provide a runway for continued development. Relative to industry peers like Amgen and Genmab, Zymeworks remains smaller in scale but holds potential upside if its ADCs gain market traction. The company's pipeline and recent FDA clearances are its primary catalysts, differentiating it from peers focused on other therapeutic areas. --- Earnings Report Outlook: Zymeworks is scheduled to report its second quarter 2025 financial results on August 7, 2025. Historical performance indicates a trajectory typical of biotech firms, with the focus on pipeline updates over immediate financial results. Analyst consensus estimates may vary, but expectations will likely hinge on updates regarding clinical trials and partnership developments. The upcoming earnings report is pivotal for understanding cash burn rates and R&D expenditures, crucial for assessing the company's financial health and operational efficiency moving forward. --- Sector Performance Overview: Zymeworks operates within the biotechnology sector, which has shown resilience and growth potential, particularly in the realm of therapeutic advancements and drug development. The sector is buoyed by innovation in monoclonal and bispecific antibodies, with a market forecast to expand significantly by 2035. However, biotech stocks are typically volatile, influenced by clinical trial outcomes and regulatory approvals. In comparison to other sectors, biotechnology remains a high-risk domain, appealing to investors willing to engage with its inherent uncertainties for potential long-term gains. - Funds were net buyers of $ZYME during the previous reporting quarter. - Funds with large holdings in $ZYME include: - EcoR1 Capital LLC, MV: $206MM. Fund Rank: 55% ecor1cap.com - BVF Partners LP, MV: $51MM. Fund Rank: 80% www.bvflp.com - Perceptive Advisors LLC, MV: $22MM. Fund Rank: 61% www.perceptivelife.com - Granahan Investment Management Inc, MV: $5MM. Fund Rank: 70% www.granahan.com - Farallon Capital Management LLC, MV: $5MM. Fund Rank: 70% www.faralloncapital.com - Last 10 days performance: -12% - Last 30 days performance: -3% - Last 90 days performance: -3% Some of the latest news articles: - Title: Bispecific Antibodies Market Report 2025- 2035, with Profiles of Akeso Biopharma, Alexion, Amgen, Genmab, Immunocore, Linton Pharm, Merck, OncXerna Therapeutics, Zymeworks, and More Publication Date: 7/29/2025 3:03:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/bispecific-antibodies-market-report-2025-150300392.html?.tsrc=rss - Title: Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate Publication Date: 7/28/2025 10:00:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/zymeworks-announces-fda-clearance-investigational-100000800.html?.tsrc=rss - Title: Zymeworks (ZYME) Surges 7.1%: Is This an Indication of Further Gains? Publication Date: 7/18/2025 1:58:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/zymeworks-zyme-surges-7-1-135800828.html?.tsrc=rss - Title: Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025 Publication Date: 7/17/2025 10:00:00 AM, Source: yahoo Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Aug. 2 at 3:50 PM
$ZYME Check what they did to Prta just before starting a massive breakout to $80...look familiar? False breakout followed by a big low volume selloff through all important levels
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FetchDog
FetchDog Aug. 1 at 3:31 PM
$ZYME Renewed starter position here ate $12.37 - the next ER may start an uptrend. I'll try to grab a bit more on Monday which I expect will be another down market day. ZYME has 11 trading days into a negative downtrend. Downtrends rarely last more than 10 trading days.
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Jul. 31 at 2:28 PM
$ZYME this is looking an awful lot like flush before news. False breakout followed by 10 straight low volume red candles that flushed multiple supports and every moving avg See what happens next week with jazz and ZYME earnings
0 · Reply
Fast_Eddie_Felson
Fast_Eddie_Felson Jul. 30 at 7:54 PM
$ZYME getting rid of this trash at 15 once we get some random pump to it. They are just doing fuck all.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jul. 29 at 8:48 PM
Commercial-stage oncology focused bios that sell within 2 years of FDA approval deliver the best returns in the peer group (versus share prices as of FDA approval). 14 of the 16 oncology focused bios that sold at meaningful gains were sold within 2 years. 7 of the 8 that sold at large losses (excl 3 that went bankrupt) waited for more than 2 years to sell. Attached is a list of all new comm'l-stage oncology focused bios since 1/1/2020 (excl. ONC). History suggests those with 1st approvals within the last year are most likely to exit via M&A at gains. Of course times change & we could be proven wrong in the future. If we had to guess, and that's all it is, we'd guess the bios in green are most likely to sell within the next 12 months. This is for entertainment purposes only. There is zero chance we will be 100% right $URGN (with recent 2nd approval) $AUTL $ZYME $FENC (they've been trying to sell for years) & $LEGN Of the 35 still independent, only 7 trade higher today.
3 · Reply
Lol_at_ur_bags
Lol_at_ur_bags Jul. 29 at 6:19 PM
$ZYME Maybe some updates/progress to come this week…..
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Latest News on ZYME
Zymeworks Inc. (ZYME) Q1 2025 Earnings Call Transcript

May 8, 2025, 11:00 PM EDT - 3 months ago

Zymeworks Inc. (ZYME) Q1 2025 Earnings Call Transcript


Zymeworks: Poised For Growth With Platform Validation

Apr 28, 2025, 10:48 AM EDT - 3 months ago

Zymeworks: Poised For Growth With Platform Validation


Zymeworks Inc. (ZYME) Q4 2024 Earnings Call Transcript

Mar 5, 2025, 8:43 PM EST - 5 months ago

Zymeworks Inc. (ZYME) Q4 2024 Earnings Call Transcript


3 Biotech Stocks With Notable Insider Buying

Jan 22, 2025, 12:29 PM EST - 7 months ago

3 Biotech Stocks With Notable Insider Buying

AUPH AZN COGT JAZZ ONC XBI


Zymeworks Inc. (ZYME) Q3 2024 Earnings Call Transcript

Oct 31, 2024, 10:05 PM EDT - 9 months ago

Zymeworks Inc. (ZYME) Q3 2024 Earnings Call Transcript


Zymeworks Approaching A Moment Of Truth With Zanidatamab

Sep 27, 2024, 2:47 PM EDT - 11 months ago

Zymeworks Approaching A Moment Of Truth With Zanidatamab


Zymeworks Inc. (ZYME) Q2 2024 Earnings Call Transcript

Aug 1, 2024, 10:58 PM EDT - 1 year ago

Zymeworks Inc. (ZYME) Q2 2024 Earnings Call Transcript


jimmythetulip
jimmythetulip Aug. 6 at 2:51 PM
$ZYME this stock just doesn’t seem to make any sense…
0 · Reply
twogloves
twogloves Aug. 6 at 2:22 PM
$ZYME big money buying 9/19 15c at the ask 👀👀
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Aug. 5 at 8:41 PM
$ZYME no delays announced by JAZZ again, phase 3 data expected 4th q
0 · Reply
ChessGM
ChessGM Aug. 2 at 6:43 PM
$ZYME "Heads up alert! Upcoming earnings on Thursday, 8/7/2025 for $ZYME Neutral (5.2) --- Detailed Financial Analysis: Zymeworks Inc. (NASDAQ: ZYME) is a clinical-stage biotechnology company focused on the development of multifunctional biotherapeutics. Recent strategic moves, such as the FDA clearance of ZW251, a novel glypican 3-targeted topoisomerase 1 inhibitor, highlight Zymeworks' potential to advance in the oncology space, particularly in hepatocellular carcinoma. Despite the promising pipeline, the stock's recent 7.1% surge may not indicate sustained momentum, as reflected by the lack of significant earnings estimate revisions. On a quantitative front, Zymeworks operates as a high-risk, high-reward entity typical of pre-revenue biotech firms. The company's P/E ratio is not applicable due to its unprofitable status, which is common in the sector as companies focus heavily on R&D rather than immediate profitability. Key financial metrics to watch include revenue forecasts tied to successful drug development and partnerships. While EPS growth remains negative, the company's cash reserves and strategic partnerships provide a runway for continued development. Relative to industry peers like Amgen and Genmab, Zymeworks remains smaller in scale but holds potential upside if its ADCs gain market traction. The company's pipeline and recent FDA clearances are its primary catalysts, differentiating it from peers focused on other therapeutic areas. --- Earnings Report Outlook: Zymeworks is scheduled to report its second quarter 2025 financial results on August 7, 2025. Historical performance indicates a trajectory typical of biotech firms, with the focus on pipeline updates over immediate financial results. Analyst consensus estimates may vary, but expectations will likely hinge on updates regarding clinical trials and partnership developments. The upcoming earnings report is pivotal for understanding cash burn rates and R&D expenditures, crucial for assessing the company's financial health and operational efficiency moving forward. --- Sector Performance Overview: Zymeworks operates within the biotechnology sector, which has shown resilience and growth potential, particularly in the realm of therapeutic advancements and drug development. The sector is buoyed by innovation in monoclonal and bispecific antibodies, with a market forecast to expand significantly by 2035. However, biotech stocks are typically volatile, influenced by clinical trial outcomes and regulatory approvals. In comparison to other sectors, biotechnology remains a high-risk domain, appealing to investors willing to engage with its inherent uncertainties for potential long-term gains. - Funds were net buyers of $ZYME during the previous reporting quarter. - Funds with large holdings in $ZYME include: - EcoR1 Capital LLC, MV: $206MM. Fund Rank: 55% ecor1cap.com - BVF Partners LP, MV: $51MM. Fund Rank: 80% www.bvflp.com - Perceptive Advisors LLC, MV: $22MM. Fund Rank: 61% www.perceptivelife.com - Granahan Investment Management Inc, MV: $5MM. Fund Rank: 70% www.granahan.com - Farallon Capital Management LLC, MV: $5MM. Fund Rank: 70% www.faralloncapital.com - Last 10 days performance: -12% - Last 30 days performance: -3% - Last 90 days performance: -3% Some of the latest news articles: - Title: Bispecific Antibodies Market Report 2025- 2035, with Profiles of Akeso Biopharma, Alexion, Amgen, Genmab, Immunocore, Linton Pharm, Merck, OncXerna Therapeutics, Zymeworks, and More Publication Date: 7/29/2025 3:03:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/bispecific-antibodies-market-report-2025-150300392.html?.tsrc=rss - Title: Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate Publication Date: 7/28/2025 10:00:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/zymeworks-announces-fda-clearance-investigational-100000800.html?.tsrc=rss - Title: Zymeworks (ZYME) Surges 7.1%: Is This an Indication of Further Gains? Publication Date: 7/18/2025 1:58:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/zymeworks-zyme-surges-7-1-135800828.html?.tsrc=rss - Title: Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025 Publication Date: 7/17/2025 10:00:00 AM, Source: yahoo Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Aug. 2 at 3:50 PM
$ZYME Check what they did to Prta just before starting a massive breakout to $80...look familiar? False breakout followed by a big low volume selloff through all important levels
0 · Reply
FetchDog
FetchDog Aug. 1 at 3:31 PM
$ZYME Renewed starter position here ate $12.37 - the next ER may start an uptrend. I'll try to grab a bit more on Monday which I expect will be another down market day. ZYME has 11 trading days into a negative downtrend. Downtrends rarely last more than 10 trading days.
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Jul. 31 at 2:28 PM
$ZYME this is looking an awful lot like flush before news. False breakout followed by 10 straight low volume red candles that flushed multiple supports and every moving avg See what happens next week with jazz and ZYME earnings
0 · Reply
Fast_Eddie_Felson
Fast_Eddie_Felson Jul. 30 at 7:54 PM
$ZYME getting rid of this trash at 15 once we get some random pump to it. They are just doing fuck all.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jul. 29 at 8:48 PM
Commercial-stage oncology focused bios that sell within 2 years of FDA approval deliver the best returns in the peer group (versus share prices as of FDA approval). 14 of the 16 oncology focused bios that sold at meaningful gains were sold within 2 years. 7 of the 8 that sold at large losses (excl 3 that went bankrupt) waited for more than 2 years to sell. Attached is a list of all new comm'l-stage oncology focused bios since 1/1/2020 (excl. ONC). History suggests those with 1st approvals within the last year are most likely to exit via M&A at gains. Of course times change & we could be proven wrong in the future. If we had to guess, and that's all it is, we'd guess the bios in green are most likely to sell within the next 12 months. This is for entertainment purposes only. There is zero chance we will be 100% right $URGN (with recent 2nd approval) $AUTL $ZYME $FENC (they've been trying to sell for years) & $LEGN Of the 35 still independent, only 7 trade higher today.
3 · Reply
Lol_at_ur_bags
Lol_at_ur_bags Jul. 29 at 6:19 PM
$ZYME Maybe some updates/progress to come this week…..
0 · Reply
Boris_Badenov
Boris_Badenov Jul. 29 at 12:27 PM
$ZYME Paul Moore, Ph.D., Chief Scientific Officer of Zymeworks. “Like ZW191, which is currently in clinical trials, ZW251 utilizes the same payload paired with an optimized antibody. Our observations with ZW191 in the clinic to date provide a strong foundation as we initiate clinical development of this second ADC. The wild card with this stock is the potentially new drugs in the pipeline. Bumping zw251 up in the schedule because of what they are seeing with zw191 could mean good things to come with zw191.
0 · Reply
BiotechBonesaw
BiotechBonesaw Jul. 28 at 11:18 PM
$ZYME big news for Zymeworks 🧬
1 · Reply
briefingcom
briefingcom Jul. 28 at 12:50 PM
$ZYME: Zymeworks (+8.4%)announces FDA clearance of investigational new drug application for ZW251, a novel glypican... https://www.briefing.com/in-depth-analysis/Content/Article?ArticleId=IN20250728060636ZYME&utm_campaign=inplay&utm_medium=social&utm_source=st&utm_content=view_page
0 · Reply
BigSqueezeComing
BigSqueezeComing Jul. 28 at 10:04 AM
$ZYME Zymeworks’ lead drug zanidatamab (Ziihera), developed via its Azymetric™ platform, already received FDA accelerated approval (Nov 2024) and conditional approval in China (May 2025) for HER2-positive biliary tract cancer (BTC), with pivotal Phase 3 trials underway in gastroesophageal adenocarcinoma and breast cancer.
0 · Reply
BigSqueezeComing
BigSqueezeComing Jul. 28 at 10:04 AM
$ZYME he U.S. Food and Drug Administration has cleared Zymeworks’ IND application for ZW251, a glypican‑3 (GPC3) targeted antibody–drug conjugate (ADC), marking the second ADC from Zymeworks to enter clinical development using its proprietary TOP1i payload technolog pt 14+
0 · Reply
BigSqueezeComing
BigSqueezeComing Jul. 28 at 10:03 AM
$ZYME Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate By Zymeworks Inc. | July 28, 2025, 6:00 AM
0 · Reply
Doozio
Doozio Jul. 24 at 11:25 AM
$ELTK it’s Thursday n it’s spreading. Every happens wen it’s $ZYME. 🐒🍌🧠 $TME ♾️
0 · Reply
Dylanjaret
Dylanjaret Jul. 19 at 4:50 AM
$ZYME strong finish into the close. Eyes on tomorrow’s open.
0 · Reply
maplelakeduckslayer
maplelakeduckslayer Jul. 18 at 1:40 AM
$ZYME everyone chasing Bitcoin Treasury reserves😂. This is now above all moving avgs on the daily, weekly, and monthly while breaking out of an ascending triangle Very bullish
1 · Reply
maplelakeduckslayer
maplelakeduckslayer Jul. 17 at 2:27 PM
$ZYME this is starting to squeeze shorts a bit they shorted 3 million shares under $13 and there's zero supply available here. One nugget at earnings this can be at new 52 week highs
1 · Reply
SKL05
SKL05 Jul. 17 at 2:17 PM
$ZYME something's cookin'
0 · Reply
Doozio
Doozio Jul. 10 at 5:01 PM
$INCY that $ZYME is $NOW a Thursday 🐑 🎁 in $RYTM 🐒🍌🧠⏰♾️
0 · Reply