Market Cap 1.85B
Revenue (ttm) 172.35M
Net Income (ttm) -285.42M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -165.60%
Debt to Equity Ratio 5.32
Volume 1,694,100
Avg Vol 1,434,152
Day's Range N/A - N/A
Shares Out 88.20M
Stochastic %K 17%
Beta 0.41
Analysts Strong Sell
Price Target $39.33

Company Profile

Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also developing revumenib for the treatment of R/R acute myeloid leukemia (AML) with a n...

Industry: Biotechnology
Sector: Healthcare
Phone: 781 419 1400
Website: syndax.com
Address:
730 Third Avenue, 9th Floor, New York, United States
Night_Owl_Biotech
Night_Owl_Biotech Apr. 24 at 8:49 PM
Tough week for bio & commercial-stage oncology focused bios. Investing is a marathon & not a sprint. Of the 26 we track w/MC over $300MM, only 6 traded higher. The XBI was off 4% $ANAB surged 15% beginning at 2:30 PM after disclosing a big legal win after a court in Delaware dismissed the Tesaro suit. Tesaro was acquired by GSK years ago. $LEGN traded as high at $26.50 on Monday which more or less held thru Wednesday. It appears Carvytki sales won't me materially impacted in the near-term. Just remember LEGN spend just under $1B on R&D every year. The odds of scoring a second cancer therapy are 1 in 20. $SNDX & $IOVA & $VSTM had the worst week in spite of trading at what appear to be reasonable multiples, at least versus their peers, but WTF do we know. VSTM's combo sales are tracking to CTIC's Vonjo. CTIC had no other pipeline of substance & was acquired for an EV of $1.7B This is not investment advice. We're just sharing our analysis.
1 · Reply
JFais
JFais Apr. 24 at 3:23 PM
$SNDX- themes for this year also include: -Growing use of Revuforj in maintenance setting (1-2 year+ duration) -Growing use in combination with other therapies & in earlier line patients (also boosts avg duration) -Showcase the value of first-mover advantage in r/r AML market
0 · Reply
JFais
JFais Apr. 24 at 3:14 PM
$SNDX- reminder we're still in the early stages of NPM1 launch
0 · Reply
dgbio
dgbio Apr. 24 at 1:40 PM
$SNDX Historically, shifting report to an earlier date means good results or a big news.
0 · Reply
PennyPoacher
PennyPoacher Apr. 24 at 12:27 PM
$SNDX I wonder if they’re doing earnings a little earlier to try and stop the hammering 🤔
0 · Reply
mulc
mulc Apr. 24 at 11:27 AM
$SNDX April 30 Q1 results, even better. Let the climb begin 🔥📈.
0 · Reply
mulc
mulc Apr. 24 at 10:19 AM
$SNDX Maybe turnaround starts today 🤞. Hope hedge truned off that bot 😸.
0 · Reply
rabbitsoup
rabbitsoup Apr. 23 at 11:08 PM
$SNDX If there is a bad ER coming and I say IF- At this point its's probably close to priced in with this decline. At least I hope....
0 · Reply
PennyPoacher
PennyPoacher Apr. 23 at 9:20 PM
$SNDX either we’ve got a buyout coming, a banger ER or a real bad ER coming. Hoping for one of the first 2 but in all likelihood it’s number 3. GLTA
2 · Reply
CNGLLC
CNGLLC Apr. 23 at 8:03 PM
$SNDK $SNDX I got caught with my pants down !!!
1 · Reply
Latest News on SNDX
Syndax Announces Participation in March Investor Conferences

Feb 23, 2026, 7:00 AM EST - 2 months ago

Syndax Announces Participation in March Investor Conferences


Syndax Announces Participation in November Investor Conferences

Oct 30, 2025, 7:00 AM EDT - 6 months ago

Syndax Announces Participation in November Investor Conferences


Syndax Announces Participation in September Investor Conferences

Aug 26, 2025, 7:00 AM EDT - 8 months ago

Syndax Announces Participation in September Investor Conferences


Syndax Announces Participation in June Investor Conferences

May 29, 2025, 7:00 AM EDT - 11 months ago

Syndax Announces Participation in June Investor Conferences


Syndax Announces Participation in May Investor Conferences

May 8, 2025, 7:00 AM EDT - 1 year ago

Syndax Announces Participation in May Investor Conferences


US FDA approves Syndax's blood cancer drug

Nov 15, 2024, 6:26 PM EST - 1 year ago

US FDA approves Syndax's blood cancer drug


Night_Owl_Biotech
Night_Owl_Biotech Apr. 24 at 8:49 PM
Tough week for bio & commercial-stage oncology focused bios. Investing is a marathon & not a sprint. Of the 26 we track w/MC over $300MM, only 6 traded higher. The XBI was off 4% $ANAB surged 15% beginning at 2:30 PM after disclosing a big legal win after a court in Delaware dismissed the Tesaro suit. Tesaro was acquired by GSK years ago. $LEGN traded as high at $26.50 on Monday which more or less held thru Wednesday. It appears Carvytki sales won't me materially impacted in the near-term. Just remember LEGN spend just under $1B on R&D every year. The odds of scoring a second cancer therapy are 1 in 20. $SNDX & $IOVA & $VSTM had the worst week in spite of trading at what appear to be reasonable multiples, at least versus their peers, but WTF do we know. VSTM's combo sales are tracking to CTIC's Vonjo. CTIC had no other pipeline of substance & was acquired for an EV of $1.7B This is not investment advice. We're just sharing our analysis.
1 · Reply
JFais
JFais Apr. 24 at 3:23 PM
$SNDX- themes for this year also include: -Growing use of Revuforj in maintenance setting (1-2 year+ duration) -Growing use in combination with other therapies & in earlier line patients (also boosts avg duration) -Showcase the value of first-mover advantage in r/r AML market
0 · Reply
JFais
JFais Apr. 24 at 3:14 PM
$SNDX- reminder we're still in the early stages of NPM1 launch
0 · Reply
dgbio
dgbio Apr. 24 at 1:40 PM
$SNDX Historically, shifting report to an earlier date means good results or a big news.
0 · Reply
PennyPoacher
PennyPoacher Apr. 24 at 12:27 PM
$SNDX I wonder if they’re doing earnings a little earlier to try and stop the hammering 🤔
0 · Reply
mulc
mulc Apr. 24 at 11:27 AM
$SNDX April 30 Q1 results, even better. Let the climb begin 🔥📈.
0 · Reply
mulc
mulc Apr. 24 at 10:19 AM
$SNDX Maybe turnaround starts today 🤞. Hope hedge truned off that bot 😸.
0 · Reply
rabbitsoup
rabbitsoup Apr. 23 at 11:08 PM
$SNDX If there is a bad ER coming and I say IF- At this point its's probably close to priced in with this decline. At least I hope....
0 · Reply
PennyPoacher
PennyPoacher Apr. 23 at 9:20 PM
$SNDX either we’ve got a buyout coming, a banger ER or a real bad ER coming. Hoping for one of the first 2 but in all likelihood it’s number 3. GLTA
2 · Reply
CNGLLC
CNGLLC Apr. 23 at 8:03 PM
$SNDK $SNDX I got caught with my pants down !!!
1 · Reply
mulc
mulc Apr. 23 at 5:21 PM
$SNDX No sign of bottom sadly. Turnaround might start next week. Will be very interesting to see incy and kura results next week following by SNDX on May 4. Revuforj should kill it I am sure.
3 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 23 at 3:59 PM
$SNDX is now (intra-day 4/23/26) off 16% from its 4/2/26 high & off $2.00+ over the last 3 trading days, though the day is far from over. As @Burning_Cash noted, historically, large drops before an earnings release are not good omens for shareholders. Worse, yesterday's large decline on 3 week high trading volumes suggest, not confirm but suggest, there was a criminal leak of insider or non-public information. There has not been a PR issued in 2 months, no SEC filing in the last 3 weeks. While a minor Q1 26 revenue miss may not appear catastrophic by itself, it could be an omen for more large drops in longer-term analysts forecast. Longer-term forecasts drive M&A exit valuations. FY29 (Year 4) consensus was $950MM ish a few months ago. FY29 (Year 4) consensus is now $890MM. Recall bankers like Centerview Partners use Year 4 multiples in fairness opinions. The flip side is, and this is not investment advice but, it may be a great time to add SNDX. $INCY $XBI $IBB
2 · Reply
wave12
wave12 Apr. 23 at 2:48 PM
$SNDX Why did the uptrend break? I still don't see a good reason.
1 · Reply
mulc
mulc Apr. 23 at 10:07 AM
$SNDX I see premarket volume 1 😅 no reason to panic just yet hehe.
0 · Reply
Burning_Cash
Burning_Cash Apr. 23 at 9:00 AM
$SNDX Not looking great… More often than not, price action like we’ve seen here means news of some sort leaked. It’s unlikely to be good news in our case. Hope I’m wrong, but if not I at least managed to sell the Jan 40s for a premium of 3.15 when this was 25-ish. GLTA
1 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 22 at 8:34 PM
$SNDX continues to trade lower down 12.2% the last few weeks while the $XBI & $NDAQ continue to surge to nosebleed valuations. Does anyone believe this is a good omen as SNDX reports Q126 results of operations in 2 weeks? SNDX investors should be outraged if, as a result of a Q126 miss, analysts revise their SNDX forecasts lower again. We have no idea what multiple of revenue SNDX might be worth in a traditional revenue multiple formula but we do know the revenue portion of the revenue multiple formula keeps moving lower. This will inevitably lead to a lower valuation. I hope we are proven wrong. How many believe SNDX should have accepted the multiple offers received from Incyte to date? Obviously, we cannot be certain $INCY has offered to buy SNDX but we bet the odds are better than 70/30 There has not been 1, not 1, peer comm'l-stage oncology focused bio of the 61 since 1/1/13 that has gone on to develop meaningful gains for shareholders by staying independent, possibly excl BPMC
4 · Reply
growingentropy
growingentropy Apr. 22 at 8:14 PM
$SNDX I stopped out. I am officially out of the SNDX business after getting in at 13. Should have sold closer to 24, but hey. That's what stop losses are for. Lol I still think this is ripe for a partnership, merger or acquisition. But now I take a higher percentage play and keep it moving.
1 · Reply
HLR78613
HLR78613 Apr. 22 at 8:08 PM
$SNDX traders getting ready for news. Good or bad. Still very
0 · Reply
Burning_Cash
Burning_Cash Apr. 22 at 7:44 PM
0 · Reply
rabbitsoup
rabbitsoup Apr. 22 at 7:27 PM
$SNDX Wow....Yuck
0 · Reply
mulc
mulc Apr. 22 at 7:26 PM
$SNDX Lets go back to 8$ ffs…not selling a penny what pos today.
0 · Reply
growingentropy
growingentropy Apr. 22 at 6:51 PM
$SNDX we came within a NICKEL of my $22 stop loss. Pivot! You were the chosen one! Lol
0 · Reply