Syndax Pharma SNDX

$18.22 -0.58 (-3.09%)

Valuation

Market cap
1,615,804,000
Revenue TTM
$172,350,000
Net income TTM
$-285,420,000
PE ratio
0.00
Forward PE
—
Profit margin
-165.60%
Debt to equity
16.16

Trading

Volume
1,431,500
Avg volume
1,521,538
Day's range
$18.05 – $18.87
Shares out
88,610,000
Stochastic %K
92%
Beta
0.37
Analysts
Strong Sell
Price target
$37.25

Price

Company profile

Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also dev...

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Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also developing revumenib for the treatment of R/R acute myeloid leukemia (AML) with a nucleophosmin 1 mutation (mNPM1) and in combination with standard-of-care agents in mNPM1 AML or KMT2Ar acute leukemia, as well as for metastatic colorectal cancer; axatilimab to treat idiopathic pulmonary fibrosis; and Entinostat, a Class 1 HDAC inhibitor. It has an agreement with Eddingpharm International Company Limited for licensing, development, and commercialization of Entinostat. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in New York, New York.

Industry
Biotechnology
Sector
Healthcare
Phone
781 419 1400
Website
https://syndax.com
Address
730 Third Avenue, 9th Floor, New York, United States

Latest news

Stocktwits

Quantumup Oct 1, 6:24 PM
H.C. Wainwright reiterated $SNDX Buy; PT $38 $KURA $ABBV - RHHBY OTSKY BMY INCY AVLN SNY H.C. Wainwright said in its note: Ahead of 3Q earnings, we completed a deeper diligence effort around NPM1m AML biology and market dynamics that provides a granular understanding of the unique headwinds and underappreciated opportunities within R/R NPM1m AML. Our work centered on revisiting commercial assumptions for the NPM1m AML market as compared to KMT2Ar. We spoke to leading hematologist-oncologists to gain a quick perspective on how targeted therapies like Revuforj are being integrated into existing treatment algorithms, and how those protocols diverge between different genetic subsets of AML in both the frontline and R/R setting. Overall, we came away with a nuanced view of the NPM1m market where frequent actionable co-mutations create headwinds from established targeted therapies in treatment sequencing, rather than from menin inhibitors.
0 replies
OnlyFibs Sep 30, 11:55 PM
$SNDX | Snapshot 📊⚡ • Business: Syndax Pharmaceuticals is a commercial-stage biotech advancing targeted therapies for blood cancers and immune-mediated diseases. • Commercial Assets: Commercializing Revuforj (menin inhibitor for acute leukemia) and Niktimvo (anti-CSF-1R antibody for chronic GVHD). • Bias & Conviction: Bullish Trendline Reversal | Moderate-High Conviction (Bouncing off primary trendline support at $18.15 with back-to-back Jan 2027 bullish LEAP call sweeps). 🎯 Key Levels: 🐂 Bull Trigger: $19.14 🚀 Targets: $22.17 / $25.00 / $25.50 🛡️ Support: $18.15 / $18.00 ⚠️ Risk: $17.50 / $16.50 🔥 Volume & Flow: • 🟢 Repeated institutional call buying in Jan 2027 $22 and $24 Calls at/above ask ($110.7K+ total premium). #SNDX #stocks #finance #hovdid
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JFais Sep 30, 7:52 PM
$SNDX - rebound continuation ahead of year-end catalysts
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Burning_Cash Sep 30, 7:35 PM
$SNDX Stock's being positioned for the upcoming catalysts?
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Quantumup Sep 29, 7:28 PM
Jefferies reiterated $SNDX Buy-$35 and said -- SNDX will report Ph2 MAXPIRe data for axatilimab (anti-CSF-1R) in IPF in 4Q. [Largest pipeline oppy—peak TAM basis = >$10B US—not currently reflected in the stock—despite good PoS] $INCY $BMY AVLN RHHBY SNY KURA AZN ABBV Here's what else Jefferies had to say in its note to investors: https://x.com/Quantumup1/status/2105016524356337974?s=20
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Night_Owl_Biotech Sep 28, 7:40 PM
A history of what's happend to the share prices of all 65 new commercial-stage oncology focused bios post FDA approval, back to 1/1/2013 (sorted by PDUFA date). The evidence appears overwhelming shareholder value is maximized via M&A exit, and in 90% of these cases within 2 years of FDA approval. Studies from industry, government & academia looking at thousands of drug development programs over the last 50 years conclude only 95-98% of new cancer drugs in Phase 1 are never approved. This is probably why 95-98% of clinical-stage oncology focused bios fail. Of course there are exceptions $NUVB ? Common sense suggests this space is ripe for consolidation. Everyone wins, including the healthcare community at large via scale to best control costs. $SNDX should be the poster boy for the phenomenon. Had one invested $1,000 in each bio 2 days post approval, the collective investment would be worth $64,775 intra-day 9/28/26. This is not investment advice. The data could be wrong $IMCR $CELC $LEGN
5 replies
MeninWatcher Sep 28, 6:35 PM
$BMEA & $SNDX Syndax would probably be a small upfront option with full funding of a revumenib/BMF-500 combination study. If the combination performed well, Syndax could exercise worldwide rights, pay Biomea a larger exercise fee and milestones, and potentially repeat its axatilimab strategy by later sharing commercialization with a larger company. Syndax know about these deals and now they are making money, could this be the first real partnership
3 replies
JFais Sep 25, 4:36 PM
$SNDX (L) Syndax Pharmaceuticals: Buy The Pullback Ahead Of Q4 Readouts https://seekingalpha.com/article/4949802?gt=51823ba909f173ec
0 replies