Market Cap 1.20B
Revenue (ttm) 0.00
Net Income (ttm) -122.53M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 326,770
Avg Vol 974,398
Day's Range N/A - N/A
Shares Out 57.60M
Stochastic %K 45%
Beta -1.88
Analysts Strong Sell
Price Target $76.00

Company Profile

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions. The company also develops ACCG-2671, which is in pre...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 457 1978
Address:
601 Gateway Boulevard, Suite 900, South San Francisco, United States
BiotechInvestor94
BiotechInvestor94 Sep. 15 at 6:00 PM
$MTSR $VKTX $GPCR I'm honestly bullish for all 3. They all have pros and cons but each has selling factors. Metsera has combinability, low API, dosing. Structure has low COGS (small molecule) with the ability to have better results at the highest dose of Aleniglipron compared to orforglipron (IF tolerability is okay with their slower titration schedule for 2B). Viking between the 3 as it stands, has the most clinically advanced pipeline (Phase 3 study well underway), and best efficacy and tolerability (despite the short attack on discontinuation which is more about trial design). Viking in comparison to Metsera is more affordable market cap wise although I like Metsera better long term. In my opinion devaluation was due to Obesity "bubble pop" by Novo flops which encouraged shorts and sell off pressure. The TAM for these drugs are too high though, eventually the new bull run will happen. I anticipate a biotech bull run from Obesity and from breakthroughs in AI drugs from some TechBios.
0 · Reply
BiotechInvestor94
BiotechInvestor94 Sep. 15 at 5:58 AM
$GPCR Wellington owns a lot of shares and its less competition in the oral space than the crowded injectables. I like Metsera alot but TAM and market penetration matter for return on investment. Overall I think Metsera the better long term differentiated play but structure could give better returns quicker. Structure valued 3 times as less too, so more affordable for BP partnership and/or buyout although they are prioritizing a partnership strategy per CEO comments this year.
0 · Reply
highnihilism
highnihilism Sep. 10 at 11:34 AM
$GPCR Nothing material. Claims it’s funded through 2027 while inching a Phase 2b obesity study toward Q4 2025 data. Biotech’s favorite pastime: burn cash, promise results. #ETSY Etsy’s platform engagement & merchant growth are reinforcing the $72 level. Consumer-spending resilience (whimsigoth, fetish fashion, handmade crafts, domestic charm). #SG Sweetgreen’s luxury athleisure lifestyle setting: bright & clean interior, crisp greens, bright wooden textures (post-class vibe) is reinforcing the $18 level. Where energized femininity resonates. #XHB Homebuilder demand trends & housing supply dynamics are reinforcing the $120 level. Fed rate-cut speculation & “golden cross” approaching. #BTC Bitcoin’s on-chain metrics & institutional flows are propping up the $112,000 level. Fed rate-cut speculation & “liquidity expansion.”
0 · Reply
BiotechInvestor94
BiotechInvestor94 Sep. 8 at 6:45 PM
$GPCR starting to like this opportunity given how much praise Lily has for Orfo. The trial for 2b has a very favorable titration schedule and will use the better formulation capsule. Also have the higher doses to increase odds of best in class efficacy as long as safety profile holds up.
0 · Reply
Quantumup
Quantumup Sep. 8 at 11:32 AM
Cantor Fitzgerald reiterated $GPCR Overweight-$65 and said, $GPCR has a big catalyst by year-end 2025 - P2B obesity readouts (ACCESS-1 and ACCESS-2 trials) for oral GLP-1 aleniglipron. $LLY $VKTX $NVO $TERN Cantor Fitzgerald added, $GPCR valuation at $1.3B market cap (EV of~$500M) remains very attractive into this catalyst. Recent orfor obesity data has created a better set-up for $GPCR with risk/reward meaningfully skewed to the upside as the bar for aleniglipron is no longer high. 2026 will have several readouts that can really differentiate $GPCR's pipeline - oral amylin, longer duration readout for higher doses of aleniglipron.
1 · Reply
fullmetalll
fullmetalll Sep. 5 at 8:59 PM
$GPCR PT Long €60
0 · Reply
Molllz_smartmoney
Molllz_smartmoney Sep. 5 at 7:02 PM
$GPCR Trade Idea 💡 Entry: 21.50 🟢 Profit Target 1: 23.47 🎯 Profit Target 2: 24.85 🚀 Profit Target 3: 26.98 🏆 Stop Loss: 18.32 🔴
0 · Reply
Meltingflame
Meltingflame Sep. 5 at 5:06 PM
$GPCR I hope news drops next week. Moonshot ✨
1 · Reply
outlawinvestor1
outlawinvestor1 Sep. 5 at 4:35 PM
$GPCR great discussion at cantor conference. really gave me more confidence in my position. i think there may be a possibility that their upcoming results disappoint investors; however, i would see it as a buying opportunity if that is the case. their lead and pipeline are strong and will definitely attract a partner, at their current levels. https://sqps.onstreamsecure.com/origin/enliven/players/EnlivenPlayer.html?customerId=22&eventId=33092681&checkCompany=1&checkEmail=1&checkName=1
0 · Reply
Theflash88
Theflash88 Sep. 4 at 8:07 PM
$GPCR Doing better lately.. I expect something to happen soon.
0 · Reply
Latest News on GPCR
Structure Therapeutics CEO on latest GLP-1 developments

Mar 24, 2025, 6:26 PM EDT - 6 months ago

Structure Therapeutics CEO on latest GLP-1 developments


Final Trade: PYPL, UBER, NKE, GPCR

Mar 24, 2025, 6:23 PM EDT - 6 months ago

Final Trade: PYPL, UBER, NKE, GPCR

NKE PYPL UBER


Structure CEO on the competitive landscape for oral GLP-1 drugs

Dec 5, 2024, 6:17 PM EST - 10 months ago

Structure CEO on the competitive landscape for oral GLP-1 drugs

NVO


Structure Therapeutics CEO on GLP drugs

Jun 11, 2024, 6:37 PM EDT - 1 year ago

Structure Therapeutics CEO on GLP drugs


Structure Therapeutics stock plunges on new GLP-1 drug data

Dec 18, 2023, 8:04 AM EST - 1 year ago

Structure Therapeutics stock plunges on new GLP-1 drug data


Final Trades: Rivian, Pfizer, Treasury Bonds and more

Sep 29, 2023, 6:26 PM EDT - 2 years ago

Final Trades: Rivian, Pfizer, Treasury Bonds and more

PFE RIVN TLT


BiotechInvestor94
BiotechInvestor94 Sep. 15 at 6:00 PM
$MTSR $VKTX $GPCR I'm honestly bullish for all 3. They all have pros and cons but each has selling factors. Metsera has combinability, low API, dosing. Structure has low COGS (small molecule) with the ability to have better results at the highest dose of Aleniglipron compared to orforglipron (IF tolerability is okay with their slower titration schedule for 2B). Viking between the 3 as it stands, has the most clinically advanced pipeline (Phase 3 study well underway), and best efficacy and tolerability (despite the short attack on discontinuation which is more about trial design). Viking in comparison to Metsera is more affordable market cap wise although I like Metsera better long term. In my opinion devaluation was due to Obesity "bubble pop" by Novo flops which encouraged shorts and sell off pressure. The TAM for these drugs are too high though, eventually the new bull run will happen. I anticipate a biotech bull run from Obesity and from breakthroughs in AI drugs from some TechBios.
0 · Reply
BiotechInvestor94
BiotechInvestor94 Sep. 15 at 5:58 AM
$GPCR Wellington owns a lot of shares and its less competition in the oral space than the crowded injectables. I like Metsera alot but TAM and market penetration matter for return on investment. Overall I think Metsera the better long term differentiated play but structure could give better returns quicker. Structure valued 3 times as less too, so more affordable for BP partnership and/or buyout although they are prioritizing a partnership strategy per CEO comments this year.
0 · Reply
highnihilism
highnihilism Sep. 10 at 11:34 AM
$GPCR Nothing material. Claims it’s funded through 2027 while inching a Phase 2b obesity study toward Q4 2025 data. Biotech’s favorite pastime: burn cash, promise results. #ETSY Etsy’s platform engagement & merchant growth are reinforcing the $72 level. Consumer-spending resilience (whimsigoth, fetish fashion, handmade crafts, domestic charm). #SG Sweetgreen’s luxury athleisure lifestyle setting: bright & clean interior, crisp greens, bright wooden textures (post-class vibe) is reinforcing the $18 level. Where energized femininity resonates. #XHB Homebuilder demand trends & housing supply dynamics are reinforcing the $120 level. Fed rate-cut speculation & “golden cross” approaching. #BTC Bitcoin’s on-chain metrics & institutional flows are propping up the $112,000 level. Fed rate-cut speculation & “liquidity expansion.”
0 · Reply
BiotechInvestor94
BiotechInvestor94 Sep. 8 at 6:45 PM
$GPCR starting to like this opportunity given how much praise Lily has for Orfo. The trial for 2b has a very favorable titration schedule and will use the better formulation capsule. Also have the higher doses to increase odds of best in class efficacy as long as safety profile holds up.
0 · Reply
Quantumup
Quantumup Sep. 8 at 11:32 AM
Cantor Fitzgerald reiterated $GPCR Overweight-$65 and said, $GPCR has a big catalyst by year-end 2025 - P2B obesity readouts (ACCESS-1 and ACCESS-2 trials) for oral GLP-1 aleniglipron. $LLY $VKTX $NVO $TERN Cantor Fitzgerald added, $GPCR valuation at $1.3B market cap (EV of~$500M) remains very attractive into this catalyst. Recent orfor obesity data has created a better set-up for $GPCR with risk/reward meaningfully skewed to the upside as the bar for aleniglipron is no longer high. 2026 will have several readouts that can really differentiate $GPCR's pipeline - oral amylin, longer duration readout for higher doses of aleniglipron.
1 · Reply
fullmetalll
fullmetalll Sep. 5 at 8:59 PM
$GPCR PT Long €60
0 · Reply
Molllz_smartmoney
Molllz_smartmoney Sep. 5 at 7:02 PM
$GPCR Trade Idea 💡 Entry: 21.50 🟢 Profit Target 1: 23.47 🎯 Profit Target 2: 24.85 🚀 Profit Target 3: 26.98 🏆 Stop Loss: 18.32 🔴
0 · Reply
Meltingflame
Meltingflame Sep. 5 at 5:06 PM
$GPCR I hope news drops next week. Moonshot ✨
1 · Reply
outlawinvestor1
outlawinvestor1 Sep. 5 at 4:35 PM
$GPCR great discussion at cantor conference. really gave me more confidence in my position. i think there may be a possibility that their upcoming results disappoint investors; however, i would see it as a buying opportunity if that is the case. their lead and pipeline are strong and will definitely attract a partner, at their current levels. https://sqps.onstreamsecure.com/origin/enliven/players/EnlivenPlayer.html?customerId=22&eventId=33092681&checkCompany=1&checkEmail=1&checkName=1
0 · Reply
Theflash88
Theflash88 Sep. 4 at 8:07 PM
$GPCR Doing better lately.. I expect something to happen soon.
0 · Reply
morelong_lessshort
morelong_lessshort Aug. 31 at 6:45 PM
$GPCR $VKTX Your evaluation of the market, Viking and Viking competition completely changed from previous comments made about 10 days ago. I thought it was a spam account, but no.
0 · Reply
Theflash88
Theflash88 Aug. 28 at 7:55 PM
$GPCR Imo they’re not “astute at anything!” Look at the stock chart..
0 · Reply
ContrarianChamp
ContrarianChamp Aug. 27 at 6:47 AM
$GPCR sitting near support, reaction here will be critical.
0 · Reply
Quantumup
Quantumup Aug. 26 at 4:49 PM
$LLY $NVO $VKTX $GPCR $TERN ZLDPY AMGN RHHBY PFE AZN MRK William Blair: In what we view as yet another surprising development, orforglipron outperformed investor expectations in patients living with both overweight/obesity and type 2 diabetes, which we view as the higher-risk and more difficult-to-treat population. Based on contemporary epidemiology, roughly a quarter of overweight/obese individuals also have type 2 diabetes. Accounting for the three Phase III studies of orforglipron, we believe the franchise exhibited the highest competitive advantage in diabetes (roughly 15% of the U.S. adult population). Furthermore, patients living with type 2 diabetes often have comorbid conditions (such as hypertension or dyslipidemia), which are most commonly managed with oral medications. It is therefore our opinion that orforglipron could be seamlessly incorporated into patients' daily routines, thereby encouraging uptake.
0 · Reply
biolover
biolover Aug. 26 at 1:52 PM
$VKTX volume 1.5 m in 15 mints vs 15 k in $GPCR that should react more to $LLY news ? Something mysterious.
0 · Reply
biolover
biolover Aug. 22 at 10:47 PM
$VKTX Reminder $GPCR oral GLP1 agonist ( replica of $LLY orfoglipron) got 6-7% wt loss at 12 wks in phase 2a despite rapid escalation and with 60% Vomiting and with no placebo effect .. $PFE Danu with rapid escalation resulted in 3.7% wt loss at 12 wks with 45% vomiting Just to place them all in comparison to $VKTX oral VK2735 …
0 · Reply
DAR2487
DAR2487 Aug. 21 at 10:41 PM
$GPCR sure seems like alot of buyers have been getting in. This will likely grind up to mid 20s before news sends this back to 50+
0 · Reply
PrnceMichael
PrnceMichael Aug. 21 at 4:15 PM
$PFSA Profusa Inc (NASDAQ: PFSA) Establishes a distributor partner in Spain for Lumee Oxygen platform $GPCR $PFSA $VKTX https://www.benzinga.com/pressreleases/25/08/ab47180683/profusa-inc-nasdaq-pfsa-establishes-a-distributor-partner-in-spain-for-lumee-oxygen-platform?utm_source=articleShare via @Benzinga @MrSamuelPowers @ProfusaInc @Nasdaq
0 · Reply
biolover
biolover Aug. 21 at 12:53 PM
$GPCR $RYTM $SLNO $VKTX RYTM drug total rip off $ 400,000-500000 per year for wt loss in syndrome obesity. This is how the health care operates. Obviously supported by many bio hedge funds hoping for BO. I don’t believe this malfunctioning price disparity will last.
1 · Reply
Quantumup
Quantumup Aug. 21 at 12:38 PM
Citizens reiterated $RYTM Market Outperform-$135 and said: We are pleased that the FDA accepted the sNDA and the Priority Review speaks to the unmet need and strength of the setmelanotide submission. LLY $VKTX NVO $GPCR TERN $AARD $SLNO Citizens added:
0 · Reply