Market Cap 962.22M
Revenue (ttm) 0.00
Net Income (ttm) -122.53M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,191,420
Avg Vol 783,826
Day's Range N/A - N/A
Shares Out 57.34M
Stochastic %K 12%
Beta -1.89
Analysts Strong Sell
Price Target $79.00

Company Profile

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions. The company also develops ACCG-2671, which is in pre...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 457 1978
Address:
601 Gateway Boulevard, Suite 900, South San Francisco, United States
Theflash88
Theflash88 Aug. 5 at 7:47 PM
$GPCR POS
0 · Reply
blocktrade
blocktrade Aug. 4 at 8:00 PM
$GPCR something must have leaked. Closed at the low
0 · Reply
Theflash88
Theflash88 Aug. 4 at 7:17 PM
$MTSR My take. Near top of the list of buyout companies by big pharma.. $VKTX $ALT $MSTR $GPCR
0 · Reply
blocktrade
blocktrade Aug. 4 at 6:58 PM
$GPCR what is with this turd
0 · Reply
THECORLEONEFAMILY
THECORLEONEFAMILY Aug. 4 at 4:53 PM
$GPCR Buying.
0 · Reply
ChessGM
ChessGM Aug. 3 at 1:35 AM
$GPCR "Heads up alert! Upcoming earnings on Friday, 8/8/2025 for $GPCR Bullish (8.0) --- Analyst Report on Structure Therapeutics Inc. (NASDAQ: GPCR) Structure Therapeutics Inc. (NASDAQ: GPCR) is currently demonstrating a strong potential for growth, bolstered by positive sentiments in recent evaluations and strategic developments. The company, a clinical-stage global biopharmaceutical entity, is primarily focused on innovating oral small molecule therapeutics for metabolic diseases. The recent bullish stance taken by analysts, such as Jefferies with a price target of $79, highlights the market's confidence in Structure Therapeutics' pipeline and strategic direction, particularly heading into a catalyst-rich second half of 2025. In terms of financial metrics, while GPCR is still unprofitable, which is common in the biotech industry, the forward-looking indicators suggest substantial growth potential. Key metrics such as the Price-to-Earnings (P/E) ratio are less applicable due to its current pre-revenue status, but earnings per share (EPS) growth is expected as clinical trials progress and potential product launches approach. Revenue forecasts are optimistic, driven by the promising data from their preclinical and early-phase trials, especially concerning their novel amylin receptor-targeting therapeutics. This positions GPCR advantageously compared to its industry peers who may lack such innovative pipeline assets. Furthermore, the company's strategic focus on metabolic diseases, particularly obesity, aligns well with increasing global health priorities, potentially offering significant market opportunities. Upcoming Earnings Report Insights The upcoming earnings report for Structure Therapeutics is eagerly awaited by analysts and investors, as it will provide crucial insights into the company's financial health and operational progress. Historically, the company has been on a path of strategic investment into its research and development, which suggests expenditures will remain high as it advances its drug candidates through the clinical pipeline. Analyst consensus estimates suggest a continued focus on R&D spend, with expectations for incremental updates on trial progress and partnership developments. The potential impact on stock hinges on positive developments in their clinical trials, especially if further data continues to validate their novel therapeutic approaches. A strong report could further bolster the stock’s performance, reinforcing the bullish sentiment currently surrounding the company. Sector Performance Overview Structure Therapeutics operates within the broader biotechnology sector, which has been experiencing mixed performance due to varying macroeconomic factors and investor sentiments. However, the specific niche of metabolic disease therapeutics, particularly focusing on diabetes and obesity, has been gaining traction. This is driven by an increasing prevalence of these conditions globally and a corresponding demand for innovative treatment solutions. The sector is poised for growth, supported by advancements in biopharmaceutical technologies and a robust pipeline of potential therapeutic candidates across the industry. Structure Therapeutics’ focus on novel oral therapeutics positions it well within a sector that is gradually shifting towards more patient-friendly, non-invasive treatment options. - Funds were net sellers of $GPCR during the previous reporting quarter. - Funds with large holdings in $GPCR include: - BVF Partners LP, MV: $31MM. Fund Rank: 80% www.bvflp.com - RA Capital Management LLC, MV: $26MM. Fund Rank: 58% www.racap.com - Casdin Capital LLC, MV: $12MM. Fund Rank: 59% www.casdincapital.com - OrbiMed Advisors LLC, MV: $11MM. Fund Rank: 55% www.orbimed.com - Deerfield Management Co, MV: $6MM. Fund Rank: 90% www.deerfield.com - Last 10 days performance: -2% - Last 30 days performance: -13% - Last 90 days performance: -34% Some of the latest news articles: - Title: We Think Structure Therapeutics (NASDAQ:GPCR) Can Afford To Drive Business Growth Publication Date: 7/3/2025 3:09:10 PM, Source: yahoo URL: https://finance.yahoo.com/news/think-structure-therapeutics-nasdaq-gpcr-150910486.html?.tsrc=rss - Title: Jefferies Reiterates a Buy Rating on Structure Therapeutics (GPCR) With a $79 PT Publication Date: 6/24/2025 9:42:13 PM, Source: yahoo URL: https://finance.yahoo.com/news/jefferies-reiterates-buy-rating-structure-214213201.html?.tsrc=rss - Title: Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671 Publication Date: 6/20/2025 11:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/structure-therapeutics-announces-two-breaking-233000891.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
THECORLEONEFAMILY
THECORLEONEFAMILY Aug. 1 at 12:07 AM
$GPCR Loading if under $17.50 tomorrow.
0 · Reply
dwhall5056
dwhall5056 Jul. 31 at 5:57 PM
$GPCR Short Interest https://fintel.io/ss/us/gpcr
0 · Reply
Idvst8
Idvst8 Jul. 30 at 10:42 PM
$GPCR - I will admit. It is cheap here.
0 · Reply
biolover
biolover Jul. 30 at 10:24 PM
$GPCR $LLY $NVO $TERN $VKTX Structure drug has inferior PK qualities compared to orfoglipron. Multiple people have written on that. Most importantly is drug wider fluctuations due to short half life which may increase vomiting. Street is aware of that the SP is reflecting this big risk. If the drug is inferior to orfoglipron which 3-4 years ahead. Then it will have no usage as it is a poor duplication if drug. Oral vk2735 is a different animal, dual agonist with likely double efficacy and better tolerance. No risk of liver or cardiac toxicity. This analyst did poor job of not highlighting the risks.
1 · Reply
Latest News on GPCR
Structure Therapeutics CEO on latest GLP-1 developments

Mar 24, 2025, 6:26 PM EDT - 4 months ago

Structure Therapeutics CEO on latest GLP-1 developments


Final Trade: PYPL, UBER, NKE, GPCR

Mar 24, 2025, 6:23 PM EDT - 4 months ago

Final Trade: PYPL, UBER, NKE, GPCR

NKE PYPL UBER


Structure Therapeutics CEO on GLP drugs

Jun 11, 2024, 6:37 PM EDT - 1 year ago

Structure Therapeutics CEO on GLP drugs


Structure Therapeutics stock plunges on new GLP-1 drug data

Dec 18, 2023, 8:04 AM EST - 1 year ago

Structure Therapeutics stock plunges on new GLP-1 drug data


Final Trades: Rivian, Pfizer, Treasury Bonds and more

Sep 29, 2023, 6:26 PM EDT - 2 years ago

Final Trades: Rivian, Pfizer, Treasury Bonds and more

PFE RIVN TLT


Structure Therapeutics Appoints Ted W. Love, M.D.

Aug 3, 2023, 5:32 PM EDT - 2 years ago

Structure Therapeutics Appoints Ted W. Love, M.D.


Theflash88
Theflash88 Aug. 5 at 7:47 PM
$GPCR POS
0 · Reply
blocktrade
blocktrade Aug. 4 at 8:00 PM
$GPCR something must have leaked. Closed at the low
0 · Reply
Theflash88
Theflash88 Aug. 4 at 7:17 PM
$MTSR My take. Near top of the list of buyout companies by big pharma.. $VKTX $ALT $MSTR $GPCR
0 · Reply
blocktrade
blocktrade Aug. 4 at 6:58 PM
$GPCR what is with this turd
0 · Reply
THECORLEONEFAMILY
THECORLEONEFAMILY Aug. 4 at 4:53 PM
$GPCR Buying.
0 · Reply
ChessGM
ChessGM Aug. 3 at 1:35 AM
$GPCR "Heads up alert! Upcoming earnings on Friday, 8/8/2025 for $GPCR Bullish (8.0) --- Analyst Report on Structure Therapeutics Inc. (NASDAQ: GPCR) Structure Therapeutics Inc. (NASDAQ: GPCR) is currently demonstrating a strong potential for growth, bolstered by positive sentiments in recent evaluations and strategic developments. The company, a clinical-stage global biopharmaceutical entity, is primarily focused on innovating oral small molecule therapeutics for metabolic diseases. The recent bullish stance taken by analysts, such as Jefferies with a price target of $79, highlights the market's confidence in Structure Therapeutics' pipeline and strategic direction, particularly heading into a catalyst-rich second half of 2025. In terms of financial metrics, while GPCR is still unprofitable, which is common in the biotech industry, the forward-looking indicators suggest substantial growth potential. Key metrics such as the Price-to-Earnings (P/E) ratio are less applicable due to its current pre-revenue status, but earnings per share (EPS) growth is expected as clinical trials progress and potential product launches approach. Revenue forecasts are optimistic, driven by the promising data from their preclinical and early-phase trials, especially concerning their novel amylin receptor-targeting therapeutics. This positions GPCR advantageously compared to its industry peers who may lack such innovative pipeline assets. Furthermore, the company's strategic focus on metabolic diseases, particularly obesity, aligns well with increasing global health priorities, potentially offering significant market opportunities. Upcoming Earnings Report Insights The upcoming earnings report for Structure Therapeutics is eagerly awaited by analysts and investors, as it will provide crucial insights into the company's financial health and operational progress. Historically, the company has been on a path of strategic investment into its research and development, which suggests expenditures will remain high as it advances its drug candidates through the clinical pipeline. Analyst consensus estimates suggest a continued focus on R&D spend, with expectations for incremental updates on trial progress and partnership developments. The potential impact on stock hinges on positive developments in their clinical trials, especially if further data continues to validate their novel therapeutic approaches. A strong report could further bolster the stock’s performance, reinforcing the bullish sentiment currently surrounding the company. Sector Performance Overview Structure Therapeutics operates within the broader biotechnology sector, which has been experiencing mixed performance due to varying macroeconomic factors and investor sentiments. However, the specific niche of metabolic disease therapeutics, particularly focusing on diabetes and obesity, has been gaining traction. This is driven by an increasing prevalence of these conditions globally and a corresponding demand for innovative treatment solutions. The sector is poised for growth, supported by advancements in biopharmaceutical technologies and a robust pipeline of potential therapeutic candidates across the industry. Structure Therapeutics’ focus on novel oral therapeutics positions it well within a sector that is gradually shifting towards more patient-friendly, non-invasive treatment options. - Funds were net sellers of $GPCR during the previous reporting quarter. - Funds with large holdings in $GPCR include: - BVF Partners LP, MV: $31MM. Fund Rank: 80% www.bvflp.com - RA Capital Management LLC, MV: $26MM. Fund Rank: 58% www.racap.com - Casdin Capital LLC, MV: $12MM. Fund Rank: 59% www.casdincapital.com - OrbiMed Advisors LLC, MV: $11MM. Fund Rank: 55% www.orbimed.com - Deerfield Management Co, MV: $6MM. Fund Rank: 90% www.deerfield.com - Last 10 days performance: -2% - Last 30 days performance: -13% - Last 90 days performance: -34% Some of the latest news articles: - Title: We Think Structure Therapeutics (NASDAQ:GPCR) Can Afford To Drive Business Growth Publication Date: 7/3/2025 3:09:10 PM, Source: yahoo URL: https://finance.yahoo.com/news/think-structure-therapeutics-nasdaq-gpcr-150910486.html?.tsrc=rss - Title: Jefferies Reiterates a Buy Rating on Structure Therapeutics (GPCR) With a $79 PT Publication Date: 6/24/2025 9:42:13 PM, Source: yahoo URL: https://finance.yahoo.com/news/jefferies-reiterates-buy-rating-structure-214213201.html?.tsrc=rss - Title: Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671 Publication Date: 6/20/2025 11:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/structure-therapeutics-announces-two-breaking-233000891.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
THECORLEONEFAMILY
THECORLEONEFAMILY Aug. 1 at 12:07 AM
$GPCR Loading if under $17.50 tomorrow.
0 · Reply
dwhall5056
dwhall5056 Jul. 31 at 5:57 PM
$GPCR Short Interest https://fintel.io/ss/us/gpcr
0 · Reply
Idvst8
Idvst8 Jul. 30 at 10:42 PM
$GPCR - I will admit. It is cheap here.
0 · Reply
biolover
biolover Jul. 30 at 10:24 PM
$GPCR $LLY $NVO $TERN $VKTX Structure drug has inferior PK qualities compared to orfoglipron. Multiple people have written on that. Most importantly is drug wider fluctuations due to short half life which may increase vomiting. Street is aware of that the SP is reflecting this big risk. If the drug is inferior to orfoglipron which 3-4 years ahead. Then it will have no usage as it is a poor duplication if drug. Oral vk2735 is a different animal, dual agonist with likely double efficacy and better tolerance. No risk of liver or cardiac toxicity. This analyst did poor job of not highlighting the risks.
1 · Reply
Quantumup
Quantumup Jul. 30 at 9:20 PM
Clear Street🏁 $GPCR Buy-$61 and said, "We are initiating coverage of Structure Therapeutics with a Buy rating and a $61 PT, seeing a rare opportunity in the oral drug revolution." $LLY $VKTX $NVO $TERN AMGN PFE AZN Clear Street added, "Oral formulations are poised to disrupt the diabesity market, offering efficacy and safety that rivals, if not surpasses, current standards. $GPCR's lead asset, aleniglipron—a scalable, small-molecule oral GLP-1 inhibitor—could deliver a game-changing POC with P2b data expected by YE25. If results match $LLY's (LLY, Not Rated) orforglipron (P3 data in 3Q25) and semaglutide, this could be the next major stock catalyst. Such validation would not only cement $GPCR's platform as a formidable competitor to peptide drugs, but also spotlight its second asset, ACCG-2671—a first-in-class oral amylin receptor analog with transformative potential, set to spark strategic partnership opportunities. Clear street additionally said:
1 · Reply
blocktrade
blocktrade Jul. 28 at 12:44 AM
$GPCR overnight trading 🤔
0 · Reply
Tikdok
Tikdok Jul. 25 at 7:40 PM
$GPCR Unusual options volume. On a thinly traded name.
1 · Reply
THECORLEONEFAMILY
THECORLEONEFAMILY Jul. 25 at 3:15 PM
$GPCR Started position…
1 · Reply
Quantumup
Quantumup Jul. 24 at 1:19 PM
H.C. Wainwright reiterated $VKTX Buy-$102 after Viking announced 2Q25 financial results and said, "We continue to believe VK2735 is well-positioned within the GLP-1 landscape, across both subcutaneous and oral formulations." $GPCR $LLY NVO $TERN AMGN $SRRK Cantor reiterated $VKTX Overweight-$104 and said, "Viking announced 2Q25 earnings and while the company did not narrow timing of Phase 2 data for oral VK2735 (still 2H25), our understanding is it is simply because they do not have visibility on cleaning and ultimately timing of receipt of data from CRO. Viking has every incentive to announce these data as soon as they are available given it will inform dosing decisions for the Phase 1 maintenance study planned to start in 3Q25."
0 · Reply
twincam
twincam Jul. 22 at 3:30 AM
1 · Reply
BiotechBonesaw
BiotechBonesaw Jul. 21 at 11:36 PM
$GPCR have any $ALT $AKRO $MDGL or $VKTX checked this out as an earlier stage oral GLP-1 alternative? @squiggleburp & @Hoppanin - any interest?
4 · Reply
biolover
biolover Jul. 15 at 6:04 PM
$GPCR $RYTM $SLNO $SRRK $VKTX RYTM drug ( which is simple receptor inhibitor ) is for $400 000 per year for wt loss and not to cure the condition . This is the woke mind virus in health system. Don’t know who would feel comfortable from BP with this price long term.
2 · Reply
Quantumup
Quantumup Jul. 15 at 5:36 PM
BofA⬆️ $RYTM PT to $109 from $95 after speaking w/ KOL and said, "Improved tolerability with next-gen oral could expand HO market oppy; Reit. Buy—Positive readthrough to next-gen weekly MC4R agonist." $VKTX $GPCR LLY NVO $SRRK $SLNO AARD BofA additionally said in its note to investors:
0 · Reply
BiotechBonesaw
BiotechBonesaw Jul. 14 at 11:56 PM
$GPCR is this a better oral GLP-1 investment than $PTGX & $VKTX ? $ALT is lonely in my biotech portfolio and wants an oral GLP-1 partner. 💊 Eating a cookie bomb for dessert - may need a GLP-1 soon 🤯
1 · Reply
Quantum_Capital_LLC
Quantum_Capital_LLC Jul. 11 at 6:19 PM
$GPCR on a slide since Sept'24, down 54% in 12 months; needs to break & hold 19.75 to get back to some green days. Do your DD.
0 · Reply
Quantumup
Quantumup Jul. 11 at 5:39 PM
Goldman Sachs, on 7/10, resumed $RYTM Buy/$97 $SLNO $AARD LLY $VKTX $GPCR SRRK Goldman Sachs said in their note:
0 · Reply