Sanofi-Aventis S.A. ADR SNY

$48.46 +0.03 (0.06%)

Valuation

Market cap
116,930,016,000
Revenue TTM
$52,854,480,000
Net income TTM
$8,839,630,000
P/E (trailing)
9.18
P/E (forward)
9.49
Profit margin
16.72%
Debt to equity
0.24

Trading

Volume
2,364,800
Avg volume
3,703,198
Day's range
$48.40 – $48.96
Shares out
2,424,425,000
Stochastic %K
94%
Beta
0.31
Analysts
Moderate Buy
Price target
$53.14

Price

Company profile

Sanofi engages in the research, development, manufacture, and marketing of therapeutic solutions in Finland and Germany. It provides immunology and inflammation, rare diseases neurology, oncology, and other vaccines. It also offers poliomyelitis, pertussis, and haemophilus influenzae type b (Hib) pediatric vaccines; respiratory syncytial virus protection; hexavalent combination vaccines that includes hepatitis A, typ...

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Sanofi engages in the research, development, manufacture, and marketing of therapeutic solutions in Finland and Germany. It provides immunology and inflammation, rare diseases neurology, oncology, and other vaccines. It also offers poliomyelitis, pertussis, and haemophilus influenzae type b (Hib) pediatric vaccines; respiratory syncytial virus protection; hexavalent combination vaccines that includes hepatitis A, typhoid, yellow fever, and rabies vaccines; and Fluzone, a flu vaccine. It has a collaboration and license agreement with Exscientia to develop small-molecule for oncology and immunology; ABL Bio, Inc. to develop ABL301 for treatment of alpha-synucleinopathies; and Innate Pharma SA for cell engager program targeting B7-H3. Further, it has a collaboration agreements with Atomwise to use ATOMNET platform and Insilico Medicine to use Pharma.AI, a medicine's AI platform; Kymera Therapeutics, Inc. to develop and commercialize protein degrader therapies targeting IRAK4 in patients with immune-inflammatory diseases; Nurix Therapeutics, Inc. to develop protein degradation therapies; Denali Therapeutics Inc. to treat systemic inflammatory diseases, such as ulcerative colitis; and Adagene Inc. for development of antibody-based therapies. Additionally, it has a collaboration with Scribe Therapeutics Inc. to develop genome editing technologies; Teva Pharmaceuticals to co-develop and co-commercialize TEV'574, for treatment of ulcerative colitis and Crohn's disease; co-promotion service agreement with Provention Bio, Inc. for the commercialization of teplizumab; and antibody collaboration with Regeneron Pharmaceuticals, Inc. to develop antibodies, such as Dupixent (dupilumab) as treatment for diseases driven by type 2 inflammation. The company was formerly known as Sanofi-Aventis and changed its name to Sanofi in May 2011. Sanofi was incorporated in 1994 and is headquartered in Paris, France.

Industry
Drug Manufacturers - General
Sector
Healthcare
Phone
33 1 53 77 40 00
Website
https://www.sanofi.com
Address
46, avenue de la Grande ArmEe, Paris, France

Latest news

Stocktwits

MQuick Nov 12, 12:35 PM
$GANX its time $SNY
0 replies
TechnoFunctional Nov 10, 5:55 PM
$ABVX has identified α4β7 as its leading candidate mechanism for an Obefazimod combination, they will confirm their molecule for combo before JPM in Jan 27. Following companies have developed molecules that inhibit α4β7 $LLY Zotemtegrast (MORF-057 / LY4268989) $GILD Emvistegrast (GS-1427) — an oral, once-daily α4β7 inhibitor $ABBV ABBV-382 — an anti-α4β7 monoclonal antibody $SNY HXN-1002 — a bispecific antibody targeting both TL1A and α4β7. For a company that already owns an α4β7 molecule, acquiring Abivax could potentially create a combination franchise with two complementary mechanisms. Lilly is particularly interesting here. It already owns an oral α4β7 inhibitor and is actively testing it in combination with mirikizumab. Adding obefazimod could give Lilly another potential combination option, with a different mechanism from both drugs.
1 replies
TroyTiger Nov 9, 8:52 PM
$TGTX buyout offers will ne coming on I think, buying any little dips. 260mil revenue this Qtr, X4 = 1.040 Billion. BUT with our current growth rate, next 4 quarters makes it over 1.1Bil. $JNJ, $MRK, $LLY, $SNY taking notice.
1 replies
GreenEnergy7B Nov 9, 1:29 PM 0 replies
Harpua97 Nov 9, 3:07 AM
$VXRT 2/2 FORTRESS v5.2 ENGINE (ARGON) Institutional 6-Block Valuation and Pipeline rNPV Math (Part 2 of 2): Why Multi-Billion-Dollar Pipeline Potential Equals $0.77/Share Today SECTION 4: PIPELINE-BY-PIPELINE VALUATION RATIONALE (WHY WE ASSIGN THESE EXACT NUMBERS TODAY) Why can a pipeline with $5B+ in unrisked commercial potential be valued at $0.77/share today? In institutional biotech valuation (risk-adjusted Net Present Value, or rNPV), you cannot value an unapproved drug as if it has already passed Phase 3 and launched. You must apply three mandatory adjustments to every future dollar: 1. Clinical Probability of Success (PoS) based on empirical FDA phase-transition rates. 2. Time-Value Discounting at a 13.5% cost of capital (4.86% 10-Yr US Treasury + biotech risk premium), which cuts cash flows arriving in 2029-2034 by 50% to 65% in today's dollars. 3. Share Count Dilution (modeling 280.0M diluted shares vs. 243.7M today to account for ~15% Q1/Q2 2027 bridge financing). Here is the exact math for each pipeline asset inside Axis 1 (40% Weight): A. Balance Sheet Net Cash Floor: $0.22 / share ($61.6M risk-adjusted) - Rationale: Starts with $65.5M gross cash ($0.27/sh) and $52.5M net working capital, adjusted for near-term operating burn net of BARDA reimbursements across a 280M post-bridge share count. B. Oral COVID-19 Vaccine (Partnered with Sanofi via Dynavax): $0.46 / share Today ($128.8M rNPV) vs. $4.30 to $6.40+ / share Unrisked - The Unrisked Upside: Under the Nov 2025 license inherited by Sanofi ($SNY) in its $2.2B Dynavax buyout, Sanofi can opt in after mid-2027 Phase 2b data for a $50M cash fee, plus up to $195M in regulatory milestones, $425M in commercial milestones ($670M total cash milestones), and tiered double-digit royalties on global net sales (with Sanofi funding 100% of Phase 3). If approved as a room-temperature mucosal booster doing $1.0B to $2.0B in peak annual sales, the unrisked NPV of those milestones and royalties is $1.2B to $1.8B ($4.30 to $6.40/sh). - Why It Is Valued at $0.46/sh Today: The 5,400-patient Phase 2b trial is a head-to-head superiority/non-inferiority study against an approved mRNA comparator -- a high clinical bar. Applying a 30% PoS to the near-term $50M Sanofi opt-in (~$13.2M PV or $0.05/sh) and an empirical 15% cumulative Phase 2b-to-FDA-approval PoS to the $620M downstream milestones and discounted 2029-2035 royalty stream (~$115.6M rNPV or $0.41/sh) yields $128.8M ($0.46/sh) today. If Phase 2b succeeds and Sanofi opts in, that 30% opt-in hurdle becomes 100% and approval PoS doubles to 35%+, immediately jumping this single asset above $1.25/sh. C. Oral Norovirus Pill (Phase 2b-Ready, Unpartnered): $0.28 / share Today ($78.4M rNPV) vs. $3.50 to $10.00+ / share Unrisked - The Unrisked Upside: Norovirus causes 685M global infections (20M US) and $60B in annual economic damage with zero FDA-approved vaccines (after HilleVax failed and Moderna faced clinical holds). Furthermore, on the Nov 5 Q3 call, management noted that CDC CaliciNet data through Sept 2026 shows the GII.4 Sydney strain rebounded to 46% dominance (while GII.17 fell to 17.5%) -- matching Vaxart's existing GII.4 clinical data -- alongside a new European patent extending IP through 2036. Unrisked, a first-in-class Norovirus pill is a $2.0B to $4.0B/yr blockbuster worth $3.0B+ ($10.00+/sh). - Why It Is Valued at $0.28/sh Today: Vaxart cannot self-fund a $100M+ Phase 2b/Phase 3 Norovirus program with a Q2 2027 cash runway. Until a partner signs, an institutional model must apply a strict 12% unpartnered PoS and assume Vaxart trades away 70% of downstream economics to a pharma partner in exchange for upfront cash and trial funding, leaving $78.4M ($0.28/sh) in risk-adjusted retained value today. The day a partner signs, PoS jumps from 12% to 35%+, re-rating this slice to $0.85 to $1.50+/sh overnight. D. Avian Flu H5N1 (VXA-H5-02), Seasonal Flu, and Altesa (Vapendavir): $0.08 / share Today ($22.4M rNPV), minus -$0.16 / share Unallocated G&A - The Unrisked Upside: In Oct 2026, Vaxart published preclinical data showing 100% protection against lethal H5N1 avian flu, adding to its Phase 2 seasonal flu data (39% disease reduction vs. 27% for Sanofi's Fluzone). In addition, Altesa Biosciences is running a Phase 2b trial of Vapendavir (licensed from Vaxart in 2021), carrying up to $130M in milestones plus royalties to Vaxart at zero cost. - Why It Is Valued at $0.08/sh Today (Net -$0.08/sh after Corporate G&A): H5N1 is still preclinical (<5% PoS without a new BARDA stockpiling grant), seasonal flu is paused pending partner funding, and an 8% risk-discounted weight on Altesa's $130M milestone pool plus H5N1 option value equals $22.4M ($0.08/sh), offset by -$44.8M (-$0.16/sh) in capitalized unallocated corporate G&A burn. COMPOSITE 3-AXIS FAIR VALUE SUMMARY (TODAY): - Axis 1 (40% Weight): Risk-Adjusted rNPV SOTP = $0.88/sh ($0.22 Cash + $0.46 COVID + $0.28 Noro + $0.08 H5N1/Altesa - $0.16 G&A) -> contributes $0.352/sh. - Axis 2 (35% Weight): Tangible Balance Sheet Blend (1.45x Gross Cash / 1.75x Net Working Capital Floor) = $0.39/sh -> contributes $0.137/sh. - Axis 3 (25% Weight): Probability-Weighted Post-Phase 2b Strategic M&A Option = $1.12/sh -> contributes $0.280/sh. - Total Composite Fair Value Today = $0.77 / share ($215M Diluted Valuation). SECTION 5: THE 4 CLINICAL AND M&A VALUATION STATES (WHY "$20B / $100" TODAY IS FANTASY, AND HOW THE RE-RATING ACTUALLY WORKS) Because Sanofi can wait for mid-2027 Phase 2b data and take control of the lead COVID asset for a $50M opt-in fee, no pharma board will pay $5B to $20B today for an unpartnered $90M OTC company pre-data. Instead, $VXRT re-rates in 4 concrete steps (on 260M to 280M diluted shares): - State 1 -- Today (Pre-P2b Data, Unpartnered Noro): $185M to $225M Implied Value = $0.65 to $0.85 / sh ($0.77 Fair Value). Reflects Q2 2027 cash bridge and clinical PoS haircuts. - State 2 -- Mid-2027 Positive P2b + Sanofi $50M Opt-In (or Major Noro Partner): $450M to $750M Implied Value = $1.65 to $2.75 / sh. Eliminates going-concern risk (+$50M non-dilutive cash), proves mucosal efficacy, and triggers Nasdaq relisting. - State 3 -- Post-P2b Platform Buyout (COVID + Noro): $1.0B to $1.8B Deal Value = $3.60 to $6.50 / sh. Sanofi or rival pharma buys $VXRT outright after positive P2b to extinguish the $620M milestones/royalties and own Norovirus + H5N1. - State 4 -- Blue-Sky Phase 3 / Multi-Pipeline M&A: $2.5B to $3.5B Deal Value = $9.00 to $12.50 / sh. Requires both Phase 2b COVID success AND positive Phase 2b Norovirus data in hand (matching GSK's $2.1B Affinivax and Sanofi's $2.2B Dynavax buyouts). SECTION 6: EXTERNAL BENCHMARK DISSENT AND #1 WATCH ITEM - First-Principles 3-Axis Fair Value ($0.77/sh) vs. GuruFocus ($0.00 GF Value, 53/100 Score): Quant screens mechanically zero out negative-FCF biotechs with going-concern notes, missing $65.5M cash and Sanofi/BARDA contracts. - First-Principles ($0.77/sh) vs. Wall Street Consensus ($3.00/sh, $2.00-$4.00 range): Analysts price in State 2 / State 3 success without discounting for the Q2 2027 cash bridge. - #1 Watch Item for Q4 2026 / Q1 2027: Monitor Lincoln Park ELOC / ATM utilization vs. non-dilutive Norovirus partnering (especially now that GII.4 strain dominance has rebounded to 46%). Bridging the 1-quarter gap between Q2 2027 cash runway and mid-2027 Phase 2b data with minimal dilution below $0.50 is the single biggest driver of per-share upside.
3 replies
Harpua97 Nov 9, 3:04 AM
$VXRT 1/2 Earlier, I was asked to share how I currently value Vaxart (or more precisely… why I don’t see anyone offering >$1B - $3B as it stands today in this moment. I explained that I’m not a biotech valuations expert, but that I base it on unbiased AI, precedent, etc. For full disclosure though, here is the precise output I get from the AI investing engine I built in Argon. I built it to particularly excel at valuations, given how much that affects every other aspect of the investment. To do so, I set it up with API access to Morningstar, GuruFocus, and Unusual Whales, allowing it to see decades of financials and future revenue projections, and using each independent valuation as a challenge to its own conclusions that it must defend. It calibrated to a six-block review that considers multiple valuation methodologies and weights them to reach a conclusion. Here is the specific output from my Argon engine when prompted to underwrite Vaxart. It’s made for investing more than it’s made for debating on StockTwits, so I have it generate things like a “Good/Great/Legendary” entry zone. I’m leaving it all in there just to give the full picture: FROM FORTRESS v5.2 ENGINE (ARGON): $VXRT Institutional 6-Block Valuation and Q3 2026 10-Q Deep Dive (Part 1 of 2): What Is Vaxart Actually Worth Today vs. Post-Phase 2b Data? Here is a complete, first-principles institutional breakdown of Vaxart ($VXRT) following the Q3 2026 Form 10-Q filing and Fireside Chat (Nov 5, 2026) -- separating balance sheet reality, clinical Probability of Success (PoS) math, and Sanofi ($SNY) contract economics from both retail hype and mechanical quant screens. SECTION 1: EXECUTIVE VERDICT AND ENTRY ZONES - Classification: Clinical-Stage Binary / Speculative Mucosal Vaccine Platform (OTCQX Listed, Going-Concern Bridge Overhang) - Current Spot Price (Nov 6, 2026 Close): $0.3700 per share (243,702,034 shares = $90.17M Market Cap | $37.19M Enterprise Value) - First-Principles 3-Axis Fair Value (Probability-Weighted Today): $0.77 per share (+108.1% upside to risk-adjusted intrinsic value | Net Cash Floor: $0.22/sh | Gross Cash: $0.27/sh) Speculative Binary Entry Zones (25% / 40% / 55% Haircuts to $0.77 Fair Value): - 3-Good Zone (at or below $0.58): Achieved at spot ($0.37 trades at a -51.9% discount to probability-weighted fair value, reflecting OTC illiquidity and the Q2 2027 vs. mid-2027 financing bridge). - 2-Great Zone (at or below $0.46): Achieved at spot (below the $0.45/sh price Dynavax paid for its $5.0M equity stake in Nov 2025). - 1-Legendary Zone (at or below $0.35): Deep Net-Cash / 52-Week Low Floor ($0.34 to $0.35), where the market prices the entire clinical pipeline at near zero above gross cash ($0.27/sh) and net working capital ($0.22/sh). - Technical Setup: Trading below its 50-DMA ($0.4586) and 200-DMA ($0.5804) with a 14-Day RSI of 33.77, resting just +$0.02 to +$0.03 above its $0.34 to $0.35 52-week volume support shelf. SECTION 2: VALUATION MULTIPLE STACK AND CASH FLOOR Because Vaxart's historical revenue is predominantly pass-through BARDA clinical trial reimbursement ($10.62M in Q3 2026 vs. $72.40M in Q3 2025 as trial enrollment wound down), traditional P/E multiples are non-meaningful. Institutional biotech desks benchmark $VXRT on Price-to-Gross-Cash, Price-to-Book, Enterprise Value (EV), and Risk-Adjusted Pipeline rNPV: 1. Price / Gross Cash ($0.269/sh): Spot ($0.37) is 1.38x | 5-Yr Phase 2 Peer Median is 1.65x | 3-Good ($0.58) is 2.16x | 1-Legendary ($0.35) is 1.30x. 2. Price / Book Value ($0.272/sh): Spot ($0.37) is 1.36x | 5-Yr Biotech Peer Median is 1.80x | 3-Good ($0.58) is 2.13x | 1-Legendary ($0.35) is 1.29x. 3. Enterprise Value (EV): Spot ($0.37) is $37.19M | 5-Yr Phase 2b Vaccine Peer Median is $115.0M | 3-Good ($0.58) is $88.37M | 1-Legendary ($0.35) is $32.32M. 4. EV / 9M 2026 Revenue ($77.0M): Spot ($0.37) is 0.48x | 5-Yr Peer Median is 2.40x | 3-Good ($0.58) is 1.15x | 1-Legendary ($0.35) is 0.42x. 5. Price / Risk-Adjusted Fair Value ($0.77): Spot ($0.37) is 0.48x | Peer Benchmark is 1.00x | 3-Good ($0.58) is 0.75x | 1-Legendary ($0.35) is 0.45x. SECTION 3: Q3 2026 10-Q BALANCE SHEET AND BURN AUDIT Verified directly from Vaxart's Q3 2026 Form 10-Q (ended Sept 30, 2026, filed Nov 5, 2026): - Cash and Short-Term Investments: $65,544,000 ($35.12M cash + $30.43M short-term investments = $0.2690 per share). Cumulative BARDA cash received reached $278.0M as of Sept 30, 2026. - Government and Collaboration Receivables: $30,498,000 ($21.03M accounts receivable + $9.47M unbilled BARDA receivables) vs. $62,042,000 in accounts payable ($29.78M) and accrued current liabilities ($32.27M). - Debt and Lease Obligations: Zero traditional bank or bond debt. $7.22M in operating lease liabilities and $5.35M in liability related to the sale of future royalties ($12.57M total debt-like obligations), leaving +$52.98M (+$0.2174/sh) in Net Financial Cash and +$52.50M (+$0.2154/sh) in Net Working Capital. - Q3 2026 Burn and SBC: Revenue dropped to $10.62M (-61.0% QoQ from $27.2M in Q2; $7.5M BARDA contract + $2.9M Dynavax collaboration) while OpEx was $27.90M ($22.8M R&D + $5.1M G&A), producing a -$17.69M GAAP Net Loss (-$0.07/sh). Stock-Based Compensation (SBC) was $1.20M (11.3% of Q3 revenue, down -41% YoY), with +$2.20M in 9M 2026 operating cash flow driven by BARDA working-capital collections. - The Critical Q2 2027 vs. Mid-2027 Liquidity Bridge Risk: Management anticipates 5,400-patient BARDA Phase 2b COVID-19 topline data (400 sentinel + ~5,000 main cohort) in mid-year 2027, while stating that current cash ($65.5M) funds operations into Q2 2027 (triggering an explicit 10-Q Going Concern warning). Unless Vaxart secures a non-dilutive Norovirus partnership or incremental BARDA funding before Spring 2027, it faces a 1-to-2 quarter cash bridge (~$15M to $20M) to reach Sanofi's $50.0M post-Phase 2b COVID opt-in decision -- likely requiring selective draws on the $25.0M Lincoln Park ELOC (925,000 shares sold for ~$0.5M through Sept 30) or the $50.0M ATM (~35M to 45M shares of potential bridge dilution at $0.37 to $0.45). (CONT’D…)
1 replies
BiotechSwings Nov 8, 11:30 PM
then the back half of the month Nov 25 $SNY venglustat in type 3 Gaucher, first US shot at the brain side of the disease. Nov 27 BBIO BBP 418 in LGMD, first therapy for that form if it lands. Nov 28 $PYPD DPLEX100 for surgical infections, Saturday date so Friday is the window Nov 30 $VRTX povetacicept in IgAN and Cogent bezuclastinib in GIST, plus $GSK neladalkib still expected in November with no day given
0 replies
BiotechCatalystCalendar Nov 8, 12:39 AM
🧬 6 readouts, 1 read. $IMCR $OBX $IOVA $MRK $SNY SITC human data span dual T-cell engagers, TIL therapies and off-the-shelf NK cells. I unpack the results, safety, treatment burden and what to watch next. First readout is free. https://biotechcatalystcalendar.substack.com/p/sitc-so-far #SITC26 #Biotech #Immunotherapy
0 replies