Market Cap 3.40B
Revenue (ttm) 0.00
Net Income (ttm) -512.54M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,140,900
Avg Vol 1,650,552
Day's Range N/A - N/A
Shares Out 158.59M
Stochastic %K 92%
Beta 1.02
Analysts Strong Sell
Price Target $32.93

Company Profile

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement thera...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 866 8547
Address:
161 Oyster Point Boulevard, South San Francisco, United States
ZacksResearch
ZacksResearch Mar. 11 at 4:23 PM
$DNLI just ripped 11.8% in a month — but the real catalyst is still ahead. Investors are watching an April 5, 2026 FDA decision on tividenofusp alfa for Hunter syndrome, which could be a major growth driver and is clearly fueling the recent momentum. 👀 Big biotech catalysts can move fast — see the full setup before the decision 👉 https://www.zacks.com/stock/news/2882427/denali-gains-118-in-a-month-buy-sell-or-hold-the-stock?cid=sm-stocktwits-2-2882427-teaser-36991&ADID=SYND_STOCKTWITS_TWEET_2_2882427_TEASER_36991
0 · Reply
ZacksResearch
ZacksResearch Mar. 11 at 3:23 PM
$DNLI surges 11.8% in a month — what’s fueling the rally? 🚀 Investor optimism is high for the potential approval of tividenofusp alfa for Hunter syndrome, with a key FDA decision expected on April 5, 2026. Positive Breakthrough Therapy, Fast Track, Orphan Drug, and Rare Pediatric Disease designations underscore the drug's potential. 📈 See what makes the investment case strong for DNLI 👉 https://www.zacks.com/stock/news/2882427/denali-gains-118-in-a-month-buy-sell-or-hold-the-stock?cid=sm-stocktwits-2-2882427-body-36992&ADID=SYND_STOCKTWITS_TWEET_2_2882427_BODY_36992
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BullDonald
BullDonald Mar. 11 at 2:20 PM
$DNLI Order Placed ! Fill it . I need more.
0 · Reply
CharlieeMungerTWITS
CharlieeMungerTWITS Mar. 10 at 6:08 PM
$DNLI LETS GO
1 · Reply
CharlieeMungerTWITS
CharlieeMungerTWITS Mar. 10 at 5:09 PM
$DNLI $30 stock if fda approves Hunter syndrome indication
0 · Reply
NorthStarStats
NorthStarStats Mar. 10 at 2:30 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. $PYXS Score: 95.00 | >350% implied upside|Earnings, $AVGO Score 95.00 |100B+ in AI chip revenue expected, $GHRS Score: 95.00 |Solid Cash Runway| $42 upgrade, $DNLI Score: 95.00 |PDUFA tividenofusp alfa April 5, $LYV Score 73.00 |DOJ Setlmnt|Venue Nation Expansion
0 · Reply
BullDonald
BullDonald Mar. 9 at 7:41 PM
$DNLI Call started !
0 · Reply
Doozio
Doozio Mar. 9 at 3:34 PM
chop chop huckleberries wen the DAWN of a 🧠👀 became $DNLI of da 🐑 during 🐒🍌🧠⏰♾️
0 · Reply
BullDonald
BullDonald Mar. 7 at 1:51 PM
$DNLI - 80%+ institution ownership, - Big Pharma backing the pipelines, - The sentiment it Optimistic for the approval. - Low volume fluctuation caused by the Retail swinging it for a dollar or two. - Strong support level is 18. Should Bounce hard after shaking the paper hands. If it tests 18, I may add some to my position.🚀
0 · Reply
dgbio
dgbio Mar. 7 at 2:02 AM
$DNLI Prasad is fired again
0 · Reply
Latest News on DNLI
The Best Small-Cap Stocks to Buy Now

Aug 12, 2025, 9:47 AM EDT - 7 months ago

The Best Small-Cap Stocks to Buy Now

DNLI KYMR WAY


Denali Therapeutics ALS drug fails in mid-stage trial

Jan 6, 2025, 4:43 PM EST - 1 year ago

Denali Therapeutics ALS drug fails in mid-stage trial

DNLI


ZacksResearch
ZacksResearch Mar. 11 at 4:23 PM
$DNLI just ripped 11.8% in a month — but the real catalyst is still ahead. Investors are watching an April 5, 2026 FDA decision on tividenofusp alfa for Hunter syndrome, which could be a major growth driver and is clearly fueling the recent momentum. 👀 Big biotech catalysts can move fast — see the full setup before the decision 👉 https://www.zacks.com/stock/news/2882427/denali-gains-118-in-a-month-buy-sell-or-hold-the-stock?cid=sm-stocktwits-2-2882427-teaser-36991&ADID=SYND_STOCKTWITS_TWEET_2_2882427_TEASER_36991
0 · Reply
ZacksResearch
ZacksResearch Mar. 11 at 3:23 PM
$DNLI surges 11.8% in a month — what’s fueling the rally? 🚀 Investor optimism is high for the potential approval of tividenofusp alfa for Hunter syndrome, with a key FDA decision expected on April 5, 2026. Positive Breakthrough Therapy, Fast Track, Orphan Drug, and Rare Pediatric Disease designations underscore the drug's potential. 📈 See what makes the investment case strong for DNLI 👉 https://www.zacks.com/stock/news/2882427/denali-gains-118-in-a-month-buy-sell-or-hold-the-stock?cid=sm-stocktwits-2-2882427-body-36992&ADID=SYND_STOCKTWITS_TWEET_2_2882427_BODY_36992
0 · Reply
BullDonald
BullDonald Mar. 11 at 2:20 PM
$DNLI Order Placed ! Fill it . I need more.
0 · Reply
CharlieeMungerTWITS
CharlieeMungerTWITS Mar. 10 at 6:08 PM
$DNLI LETS GO
1 · Reply
CharlieeMungerTWITS
CharlieeMungerTWITS Mar. 10 at 5:09 PM
$DNLI $30 stock if fda approves Hunter syndrome indication
0 · Reply
NorthStarStats
NorthStarStats Mar. 10 at 2:30 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. $PYXS Score: 95.00 | >350% implied upside|Earnings, $AVGO Score 95.00 |100B+ in AI chip revenue expected, $GHRS Score: 95.00 |Solid Cash Runway| $42 upgrade, $DNLI Score: 95.00 |PDUFA tividenofusp alfa April 5, $LYV Score 73.00 |DOJ Setlmnt|Venue Nation Expansion
0 · Reply
BullDonald
BullDonald Mar. 9 at 7:41 PM
$DNLI Call started !
0 · Reply
Doozio
Doozio Mar. 9 at 3:34 PM
chop chop huckleberries wen the DAWN of a 🧠👀 became $DNLI of da 🐑 during 🐒🍌🧠⏰♾️
0 · Reply
BullDonald
BullDonald Mar. 7 at 1:51 PM
$DNLI - 80%+ institution ownership, - Big Pharma backing the pipelines, - The sentiment it Optimistic for the approval. - Low volume fluctuation caused by the Retail swinging it for a dollar or two. - Strong support level is 18. Should Bounce hard after shaking the paper hands. If it tests 18, I may add some to my position.🚀
0 · Reply
dgbio
dgbio Mar. 7 at 2:02 AM
$DNLI Prasad is fired again
0 · Reply
StocktwitsEarnings
StocktwitsEarnings Mar. 6 at 7:00 PM
$DNLI Q4 '25 Earnings Results & Recap Denali Therapeutics Inc. anticipates a PDUFA target action date of April 5, 2026, for tividenofusp alfa's accelerated approval, with DNL126's commercial launch expected by H2 2027, and plans to advance four to six new molecule entities into clinical development starting in 2026.
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BullDonald
BullDonald Mar. 5 at 2:54 PM
$DNLI Added 5k more shares to My Position. Locked for PDUFA Win 🚀
1 · Reply
BobBijawklah
BobBijawklah Mar. 4 at 6:35 PM
$IBRX I have some hot Picks folks Leading or best in class. IBRX below 9 is a buy. $SMMT will be the next iteration of pdl1 surpassing keytruda in all indications PT $35 PDUFA Nov 2026. $DNLI hunter syndrome PDUFA April 2026 PT 30 .$ACAD nuplazid and dayblue 1 billion in revenue . Remlifanserin data due out later this year. Potential revenue of Remlifanserin 4 billion. PT 35. $MLTX Merck already put a 41 dollar offer which was turned down. Trades at 18 per share PT 40.
2 · Reply
dgbio
dgbio Mar. 4 at 7:40 AM
$DNLI Full text of the CRL for Regenx. As I said: novel biomarker and unproven reference level. https://download.open.fda.gov/crl/CRL_BLA125840_20260207.pdf
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BullDonald
BullDonald Mar. 3 at 2:54 PM
$DNLI I am In 🚀 LFG
0 · Reply
moneybag888
moneybag888 Mar. 2 at 4:56 PM
1 · Reply
erevnon
erevnon Mar. 2 at 12:21 PM
BTIG maintains Denali Therapeutics $DNLI at Buy and raises the price target from $32 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
BullDonald
BullDonald Feb. 28 at 12:58 PM
$DNLI Bad earning is a Noise given every thing is going good for the company. But I could use a Pull back to reload the Boat.
2 · Reply
ZacksResearch
ZacksResearch Feb. 27 at 3:45 PM
Why $DNLI's Potential FDA Approval Could Be a Game-Changer 🚀 Denali's lead candidate, tividenofusp alfa, is under FDA review for treating Hunter syndrome, with a decision expected by April 5, 2026. The drug's breakthrough therapy designations and cash reserves of $966.2M underscore DNLI's ability to fund ongoing programs. Discover the full potential here 👉 https://www.zacks.com/stock/news/2876602/dnli-q4-loss-narrower-than-expected-hunter-syndrome-drug-in-focus?cid=sm-stocktwits-2-2876602-body-35505&ADID=SYND_STOCKTWITS_TWEET_2_2876602_BODY_35505
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ZacksResearch
ZacksResearch Feb. 27 at 2:45 PM
$DNLI loss narrows — but the real story is the pipeline 👀 Q4 loss came in narrower than expected, even with no Q4 revenues. The FDA extended the review of tividenofusp alfa, and the company still holds $966M in cash to back further advances. Cash runway + regulatory catalyst ahead — high risk, high reward setup? Full breakdown here 👉 https://www.zacks.com/stock/news/2876602/dnli-q4-loss-narrower-than-expected-hunter-syndrome-drug-in-focus?cid=sm-stocktwits-2-2876602-teaser-35504&ADID=SYND_STOCKTWITS_TWEET_2_2876602_TEASER_35504
0 · Reply
StockNews_Live
StockNews_Live Feb. 26 at 9:04 PM
$DNLI Denali Therapeutics reported financial results for the fourth quarter and full year ended December 31, 2025, and provided business highlights. The company established commercial launch readiness for t…
0 · Reply
BullDonald
BullDonald Feb. 24 at 3:45 PM
$DNLI I am Out for now : 25K+ (P/L)
0 · Reply