Market Cap 3.65B
Revenue (ttm) 0.00
Net Income (ttm) -512.54M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,232,100
Avg Vol 1,877,748
Day's Range N/A - N/A
Shares Out 158.71M
Stochastic %K 23%
Beta 0.96
Analysts Strong Sell
Price Target $34.25

Company Profile

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement thera...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 866 8547
Address:
161 Oyster Point Boulevard, South San Francisco, United States
Merlintrader
Merlintrader Jul. 25 at 1:34 PM
0 · Reply
B2iDigital
B2iDigital Jul. 24 at 9:57 PM
eXoZymes (Nasdaq: $EXOZ ) is among the first projects selected for the inaugural U.S. Department of Energy (DOE) Genesis Mission, a nationwide initiative bringing together national laboratories, universities, companies, and nonprofit organizations to accelerate scientific discovery. eXoZymes will work with Lawrence Berkeley National Laboratory to build AI-powered digital twins for its cell-free biomanufacturing platform. eXoZymes is a B2i Digital Featured Company. See the company’s profile at https://b2idigital.com/exozymes The project extends the company’s AI work from enzyme engineering into manufacturing: • With Berkeley Lab, eXoZymes will develop hybrid digital twins that combine enzyme kinetics, reactor physics, and machine learning to identify optimal operating conditions before lab validation • The award provides access to the DOE Genesis Mission Platform: advanced AI models, AI agents, and high-performance computing • Subject to DOE award negotiations, the project is expected to carry about $747,000 in total funding, including about $147,000 for eXoZymes “We believe the next generation of biomanufacturing will be built at the intersection of artificial intelligence and digital insights into biology,” said Michael Heltzen, Chief Executive Officer of eXoZymes. Read the full release: https://exozymes.com/blog/genesis-mission-2026 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
G101SPM
G101SPM Jul. 24 at 2:12 PM
#SHOWTIME International AIDS Conference (July 27-31) Scheduled to appear: $MRK BTIG Biotechnology Conference (July 27) Scheduled to appear: $DNLI, $MLTX, $PCVX
0 · Reply
Quantumup
Quantumup Jul. 23 at 6:44 PM
Morgan Stanley, in a broad research note earnings preview, ⬆️ $ASND to $275 from $256, reiterated (reit'd) Overweight; $DNLI to $36 from $35, reit'd Overweight; $EXEL to $53 from $50, reit'd Equal Weight; and $INCY to $104 from $103, reit'd Equal Weight, and said 2Q26 earnings should reinforce a shift from macro-driven trading toward stock-specific execution and differentiation.
0 · Reply
B2iDigital
B2iDigital Jul. 23 at 4:01 PM
eXoZymes (Nasdaq: $EXOZ ) frames itself as a repeatable engine for unlocking molecule classes. In a Webull webinar, Chief Commercial Officer Damien Perriman put cannabinoids forward as the next class after NCT. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 "This is not a single product company. It's a repeatable system for unlocking entire classes of molecules," Perryman told investors. Also from the presentation: • NCT is the first proof point and cannabinoids are the second, with cannabinoid receptors present on nearly every cell in the body • That reach spans metabolic, inflammatory, and neurological conditions, where access to rare cannabinoids has long been the bottleneck • eXoZymes says it can now produce rare and entirely new cannabinoids without intoxicating components, optimized toward specific therapeutic objectives Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
Merlintrader
Merlintrader Jul. 20 at 8:25 PM
Priority Review Voucher explainer: $RCKT and $DNLI turned one FDA approval into $180-205M cash. Relevant for $XBI and $IBB biotech investors. https://www.merlintrader.com/priority-review-voucher-explained-rckt-dnli-2026/
0 · Reply
B2iDigital
B2iDigital Jul. 17 at 9:10 PM
A platform that works in the lab is not yet a business. In a Webull webinar, eXoZymes (Nasdaq: $EXOZ ) pointed to a scale-up run it says clears that bar. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 Perryman framed the milestone directly: "Many technologies work in the lab, but many also fail at scale. What we've demonstrated here is that the system translates from concept to industrial conditions, and that's what turns this from a science into a viable business." The webinar detailed the run: • The company ran a 100-liter pilot at the end of last year, reporting 99% conversion of raw material to target product and 99.6% purity • The run took place at a third party after eXoZymes tech-transferred its process, operating conditions, and enzyme cascades • Management called this an operational process rather than a theoretical one, and an inflection point for investors Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
IN0V8
IN0V8 Jul. 16 at 2:38 PM
$DNLI Opportunity Deutsche Bank raises target price to $35 from $31
0 · Reply
_ivan
_ivan Jul. 16 at 6:48 AM
0 · Reply
dgbio
dgbio Jul. 15 at 4:21 PM
$DNLI Tau is still seen as an important target in Alzheimer: https://www.fiercebiotech.com/biotech/aaic-roche-very-interested-tau-despite-focus-phase-3-amyloid-alzheimers-asset
0 · Reply
Latest News on DNLI
Denali Therapeutics falls -14.1%

2026-07-14T16:05:47.000Z - 19 days ago

Denali Therapeutics falls -14.1%


Denali Therapeutics falls -12.4%

2026-07-14T14:05:10.000Z - 19 days ago

Denali Therapeutics falls -12.4%


Denali Therapeutics resumed with an Overweight at JPMorgan

2026-07-13T09:50:38.000Z - 20 days ago

Denali Therapeutics resumed with an Overweight at JPMorgan


Denali Therapeutics Transcript: AGM 2026

Jun 3, 2026, 1:00 PM EDT - 2 months ago

Denali Therapeutics Transcript: AGM 2026


Denali Therapeutics trading resumes

2026-05-21T22:35:11.000Z - 2 months ago

Denali Therapeutics trading resumes


Denali Therapeutics trading halted, news pending

2026-05-21T21:55:12.000Z - 2 months ago

Denali Therapeutics trading halted, news pending


Denali Therapeutics Slides: Corporate presentation

May 12, 2026, 4:00 PM EDT - 2 months ago

Denali Therapeutics Slides: Corporate presentation


Denali Therapeutics Quarterly report: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Denali Therapeutics Quarterly report: Q1 2026


Denali Therapeutics Earnings release: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Denali Therapeutics Earnings release: Q1 2026


Denali Therapeutics Proxy statement: Proxy filing

Apr 21, 2026, 8:00 AM EDT - 3 months ago

Denali Therapeutics Proxy statement: Proxy filing


Denali Therapeutics Proxy statement: Proxy filing

Apr 21, 2026, 8:00 AM EDT - 3 months ago

Denali Therapeutics Proxy statement: Proxy filing


Denali Therapeutics price target raised to $39 from $38 at BTIG

2026-04-06T17:15:09.000Z - 4 months ago

Denali Therapeutics price target raised to $39 from $38 at BTIG


Denali Therapeutics regains full rights to DNL593

2026-04-06T01:15:08.000Z - 4 months ago

Denali Therapeutics regains full rights to DNL593

TAK


Denali Therapeutics Transcript: Study update

Mar 25, 2026, 12:30 PM EDT - 4 months ago

Denali Therapeutics Transcript: Study update


Denali Therapeutics Press release: Study update

Mar 25, 2026, 12:30 PM EDT - 4 months ago

Denali Therapeutics Press release: Study update


Denali Therapeutics Slides: Study update

Mar 25, 2026, 12:30 PM EDT - 4 months ago

Denali Therapeutics Slides: Study update


Denali Therapeutics Transcript: Stifel 2026 Virtual CNS Forum

Mar 17, 2026, 2:00 PM EDT - 4 months ago

Denali Therapeutics Transcript: Stifel 2026 Virtual CNS Forum


Denali Therapeutics Earnings release: Q4 2025

Feb 26, 2026, 7:00 AM EST - 5 months ago

Denali Therapeutics Earnings release: Q4 2025


Denali Therapeutics Annual report: Q4 2025

Feb 26, 2026, 7:00 AM EST - 5 months ago

Denali Therapeutics Annual report: Q4 2025


Denali Therapeutics Transcript: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Transcript: Study update


Denali Therapeutics Press release: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Press release: Study update


Denali Therapeutics Slides: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Slides: Study update


Denali Therapeutics Transcript: Investor Day 2025

Dec 4, 2025, 8:30 AM EST - 8 months ago

Denali Therapeutics Transcript: Investor Day 2025


Denali Therapeutics Slides: FY 2025

Dec 4, 2025, 8:30 AM EST - 8 months ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics Earnings release: Q3 2025

Nov 6, 2025, 7:00 AM EST - 9 months ago

Denali Therapeutics Earnings release: Q3 2025


Denali Therapeutics Quarterly report: Q3 2025

Nov 6, 2025, 7:00 AM EST - 9 months ago

Denali Therapeutics Quarterly report: Q3 2025


Denali Therapeutics Slides: Corporate Presentation

Nov 5, 2025, 6:00 PM EST - 9 months ago

Denali Therapeutics Slides: Corporate Presentation


The Best Small-Cap Stocks to Buy Now

Aug 12, 2025, 9:47 AM EDT - 1 year ago

The Best Small-Cap Stocks to Buy Now

KYMR WAY


Denali Therapeutics Quarterly report: Q2 2025

Aug 11, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Quarterly report: Q2 2025


Denali Therapeutics Earnings release: Q2 2025

Aug 11, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Earnings release: Q2 2025


Denali Therapeutics Slides: Corporate Presentation

May 13, 2025, 7:00 AM EDT - 1 year ago

Denali Therapeutics Slides: Corporate Presentation


Denali Therapeutics Quarterly report: Q1 2025

May 6, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Quarterly report: Q1 2025


Denali Therapeutics Earnings release: Q1 2025

May 6, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Earnings release: Q1 2025


Denali Therapeutics Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Transcript: Stifel 2025 Virtual CNS Forum

Mar 18, 2025, 2:30 PM EDT - 1 year ago

Denali Therapeutics Transcript: Stifel 2025 Virtual CNS Forum


Denali Therapeutics Slides: FY 2025

Mar 18, 2025, 2:30 PM EDT - 1 year ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics Transcript: UBS Virtual CNS Day 2025

Mar 17, 2025, 12:00 PM EDT - 1 year ago

Denali Therapeutics Transcript: UBS Virtual CNS Day 2025


Denali Therapeutics Earnings release: Q4 2024

Feb 27, 2025, 4:00 PM EST - 1 year ago

Denali Therapeutics Earnings release: Q4 2024


Denali Therapeutics Annual report: Q4 2024

Feb 27, 2025, 4:00 PM EST - 1 year ago

Denali Therapeutics Annual report: Q4 2024


Denali Therapeutics Slides: FY 2025

Jan 14, 2025, 2:15 PM EST - 1 year ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics ALS drug fails in mid-stage trial

Jan 6, 2025, 4:43 PM EST - 1 year ago

Denali Therapeutics ALS drug fails in mid-stage trial


Denali Therapeutics Quarterly report: Q3 2024

Nov 5, 2024, 6:00 PM EST - 1 year ago

Denali Therapeutics Quarterly report: Q3 2024


Denali Therapeutics Earnings release: Q3 2024

Nov 5, 2024, 6:00 PM EST - 1 year ago

Denali Therapeutics Earnings release: Q3 2024


Denali Therapeutics Quarterly report: Q2 2024

Aug 1, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Quarterly report: Q2 2024


Denali Therapeutics Earnings release: Q2 2024

Aug 1, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Earnings release: Q2 2024


Denali Therapeutics Slides: Corporate Presentation

May 14, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Slides: Corporate Presentation


Denali Therapeutics Quarterly report: Q1 2024

May 7, 2024, 4:00 PM EDT - 2 years ago

Denali Therapeutics Quarterly report: Q1 2024


Denali Therapeutics Earnings release: Q1 2024

May 7, 2024, 4:00 PM EDT - 2 years ago

Denali Therapeutics Earnings release: Q1 2024


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2024, 8:00 AM EDT - 2 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2024, 8:00 AM EDT - 2 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Annual report: Q4 2023

Feb 27, 2024, 7:00 AM EST - 2 years ago

Denali Therapeutics Annual report: Q4 2023


Denali Therapeutics Earnings release: Q4 2023

Feb 27, 2024, 7:00 AM EST - 2 years ago

Denali Therapeutics Earnings release: Q4 2023


Denali Therapeutics Quarterly report: Q3 2023

Nov 7, 2023, 4:00 PM EST - 2 years ago

Denali Therapeutics Quarterly report: Q3 2023


Denali Therapeutics Earnings release: Q3 2023

Nov 7, 2023, 4:00 PM EST - 2 years ago

Denali Therapeutics Earnings release: Q3 2023


Denali Therapeutics Slides: FY 2023

Sep 12, 2023, 11:30 AM EDT - 3 years ago

Denali Therapeutics Slides: FY 2023


Denali Therapeutics Quarterly report: Q2 2023

Aug 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Quarterly report: Q2 2023


Denali Therapeutics Earnings release: Q2 2023

Aug 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Earnings release: Q2 2023


Denali Therapeutics Transcript: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Transcript: Study Result


Denali Therapeutics Press release: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Press release: Study Result


Denali Therapeutics Slides: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Slides: Study Result


Denali Therapeutics Quarterly report: Q1 2023

May 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Quarterly report: Q1 2023


Denali Therapeutics Earnings release: Q1 2023

May 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Earnings release: Q1 2023


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2023, 8:00 AM EDT - 3 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2023, 8:00 AM EDT - 3 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Annual report: Q4 2022

Feb 27, 2023, 4:00 PM EST - 3 years ago

Denali Therapeutics Annual report: Q4 2022


Denali Therapeutics Earnings release: Q4 2022

Feb 27, 2023, 4:00 PM EST - 3 years ago

Denali Therapeutics Earnings release: Q4 2022


Merlintrader
Merlintrader Jul. 25 at 1:34 PM
0 · Reply
B2iDigital
B2iDigital Jul. 24 at 9:57 PM
eXoZymes (Nasdaq: $EXOZ ) is among the first projects selected for the inaugural U.S. Department of Energy (DOE) Genesis Mission, a nationwide initiative bringing together national laboratories, universities, companies, and nonprofit organizations to accelerate scientific discovery. eXoZymes will work with Lawrence Berkeley National Laboratory to build AI-powered digital twins for its cell-free biomanufacturing platform. eXoZymes is a B2i Digital Featured Company. See the company’s profile at https://b2idigital.com/exozymes The project extends the company’s AI work from enzyme engineering into manufacturing: • With Berkeley Lab, eXoZymes will develop hybrid digital twins that combine enzyme kinetics, reactor physics, and machine learning to identify optimal operating conditions before lab validation • The award provides access to the DOE Genesis Mission Platform: advanced AI models, AI agents, and high-performance computing • Subject to DOE award negotiations, the project is expected to carry about $747,000 in total funding, including about $147,000 for eXoZymes “We believe the next generation of biomanufacturing will be built at the intersection of artificial intelligence and digital insights into biology,” said Michael Heltzen, Chief Executive Officer of eXoZymes. Read the full release: https://exozymes.com/blog/genesis-mission-2026 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
G101SPM
G101SPM Jul. 24 at 2:12 PM
#SHOWTIME International AIDS Conference (July 27-31) Scheduled to appear: $MRK BTIG Biotechnology Conference (July 27) Scheduled to appear: $DNLI, $MLTX, $PCVX
0 · Reply
Quantumup
Quantumup Jul. 23 at 6:44 PM
Morgan Stanley, in a broad research note earnings preview, ⬆️ $ASND to $275 from $256, reiterated (reit'd) Overweight; $DNLI to $36 from $35, reit'd Overweight; $EXEL to $53 from $50, reit'd Equal Weight; and $INCY to $104 from $103, reit'd Equal Weight, and said 2Q26 earnings should reinforce a shift from macro-driven trading toward stock-specific execution and differentiation.
0 · Reply
B2iDigital
B2iDigital Jul. 23 at 4:01 PM
eXoZymes (Nasdaq: $EXOZ ) frames itself as a repeatable engine for unlocking molecule classes. In a Webull webinar, Chief Commercial Officer Damien Perriman put cannabinoids forward as the next class after NCT. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 "This is not a single product company. It's a repeatable system for unlocking entire classes of molecules," Perryman told investors. Also from the presentation: • NCT is the first proof point and cannabinoids are the second, with cannabinoid receptors present on nearly every cell in the body • That reach spans metabolic, inflammatory, and neurological conditions, where access to rare cannabinoids has long been the bottleneck • eXoZymes says it can now produce rare and entirely new cannabinoids without intoxicating components, optimized toward specific therapeutic objectives Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
Merlintrader
Merlintrader Jul. 20 at 8:25 PM
Priority Review Voucher explainer: $RCKT and $DNLI turned one FDA approval into $180-205M cash. Relevant for $XBI and $IBB biotech investors. https://www.merlintrader.com/priority-review-voucher-explained-rckt-dnli-2026/
0 · Reply
B2iDigital
B2iDigital Jul. 17 at 9:10 PM
A platform that works in the lab is not yet a business. In a Webull webinar, eXoZymes (Nasdaq: $EXOZ ) pointed to a scale-up run it says clears that bar. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 Perryman framed the milestone directly: "Many technologies work in the lab, but many also fail at scale. What we've demonstrated here is that the system translates from concept to industrial conditions, and that's what turns this from a science into a viable business." The webinar detailed the run: • The company ran a 100-liter pilot at the end of last year, reporting 99% conversion of raw material to target product and 99.6% purity • The run took place at a third party after eXoZymes tech-transferred its process, operating conditions, and enzyme cascades • Management called this an operational process rather than a theoretical one, and an inflection point for investors Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
IN0V8
IN0V8 Jul. 16 at 2:38 PM
$DNLI Opportunity Deutsche Bank raises target price to $35 from $31
0 · Reply
_ivan
_ivan Jul. 16 at 6:48 AM
0 · Reply
dgbio
dgbio Jul. 15 at 4:21 PM
$DNLI Tau is still seen as an important target in Alzheimer: https://www.fiercebiotech.com/biotech/aaic-roche-very-interested-tau-despite-focus-phase-3-amyloid-alzheimers-asset
0 · Reply
BlueSignal
BlueSignal Jul. 15 at 4:02 PM
$BIIB is adding more data to the evolving anti-tau Alzheimer’s landscape as it presented new mid-stage results for diranersen, its antisense therapy developed with partner $IONS. The data provided further support for the role of tau biology in Alzheimer’s disease, while also highlighting that the field is still working to determine how much clinical benefit anti-tau approaches can deliver. Upcoming results from other programs, including candidates from $DNLI and $LLY, will be closely watched as the industry looks for clearer evidence on whether targeting tau can become a meaningful next step beyond amyloid therapies.
0 · Reply
dgbio
dgbio Jul. 14 at 5:37 PM
$DNLI If this is about Biogen's anti-tau results, let's think what fraction of Denali's valuation could be assigned to the anti-tau program. In my book it's nearly zero.
1 · Reply
B2iDigital
B2iDigital Jul. 14 at 5:15 PM
eXoZymes (Nasdaq: $EXOZ ) is targeting metabolic dysfunction a layer deeper than appetite. In a recent Webull webinar, Chief Commercial Officer Damien Perriman walked investors through NCT, the company's first proof point. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 "It is fundamentally different from GLP-1 drugs," Perryman said. "GLP-1s reduce appetite, whereas NCT and its activation of HNF4 alpha improves mitochondrial biogenesis and mitochondrial activity, essentially improving how the body burns fat." From the same segment: • NCT activates HNF4 alpha, a master metabolic control switch, rather than acting on a single downstream symptom • In controlled preclinical models on identical diets, eXoZymes reported 30% to 40% less weight gain in the mouse population • The company also observed improved mitochondrial function and reduced liver fat, consistent with hitting a central regulatory pathway Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
notreload_ai
notreload_ai Jul. 14 at 2:57 PM
$BIIB diranersen showed robust tau reductions (50-65%) and slowed cognitive decline by up to 26% in its Phase 2 CELIA trial. Despite missing the primary endpoint, the drug advances to Phase 3 in 2027 with a favorable safety profile. Mixed Phase 2 results still advance the competitive tau gene-silencing space including $VYGR, $ARWR, and $DNLI. https://notreload.xyz/xy/biogen-diranersen-phase-2-results-promising-tau-drug-misses-primary-endpoint/
1 · Reply
Rachaele
Rachaele Jul. 14 at 2:00 PM
$DNLI Down on any news?
2 · Reply
Raging_Bull777
Raging_Bull777 Jul. 14 at 3:11 AM
$DNLI Interview with David R. GirouxPres & CIO of T. Rowe Price: I will probably sound like a broken record highlighting a unique opportunity in SMID,biotech. Large Pharma has $500 billion patent-expiration hole to fill over the next decade that they can’t overcome with internal research and development efforts. A limited number of SMID biotech companies have the potential to be $3B to $10B revenue generators over time. Big pharma is generating strong cash flows, which allows companies to do deals. AbbVie recently agreed to buy Apogee,, Abbvie gained more than $20B in market cap when the deal was announced. It was a win-win. I expect to see a tremendous number of SMID biotechs sold in the next 5 years for a 50% to 100% premium. Today I will highlight 7: Ascendis Pharma A/S , MoonLake Immunotherapeutics , Dyne Therapeutics , Vaxcyte , Cytokinetics , CG Oncology , and Denali Therapeutics . I would be shocked if all weren’t acquired in the next few years for big premiums.
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Laynester
Laynester Jul. 9 at 2:09 PM
$AGNC $OPEN $FBRX $DNLI $ALNY [TENX] [XENE] [ASND] Things that looked like an great opportunity today. Jumped in on all. Set an [ALERT] then stop out. Good skills to all!!!
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B2iDigital
B2iDigital Jul. 8 at 11:59 PM
eXoZymes (Nasdaq: $EXOZ ) makes its case for cell-free biomanufacturing, the approach it says sidesteps where whole-cell synthetic biology has repeatedly failed to scale. Whole-cell synthetic biology has a long record of stalling at scale. In a Webull webinar, eXoZymes Chief Commercial Officer Damien Perriman laid out why the company removed the cell from the equation entirely. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 "Engineered cells have become a boulevard of broken dreams on Wall Street, and eXoZymes found a way to navigate around this problem," said Damien Perryman, Chief Commercial Officer of eXoZymes. In the webinar, Perryman also covered: • Cells evolved to survive, not to manufacture, so whole-cell systems carry biological noise, toxicity limits, and regulatory complexity into production • eXoZymes isolates the enzymes, engineers them with AI, and runs them outside the cell to produce target molecules cleanly and at scale • The result behaves more like precision chemistry than a biological production system, inspired by biology's own catalysts Watch the full webinar: youtube.com/watch?v=OmH3TaaMT20&feature=youtu.be eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
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moneybag888
moneybag888 Jul. 7 at 3:24 PM
$DNLI 😎
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moneybag888
moneybag888 Jul. 7 at 3:21 PM
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B2iDigital
B2iDigital Jun. 25 at 9:21 PM
eXoZymes (Nasdaq: $EXOZ) secures $2 million NIH grant, expanding its proprietary pharmaceutical biosolutions pipeline into non-intoxicating cannabinoids. Federal research funding extends eXoZymes’ cell-free platform further into drug discovery. eXoZymes Inc. (Nasdaq: EXOZ) has received a Notice of Award from the National Institutes of Health for a roughly $2 million Phase IIB SBIR grant to produce rare cannabinoids and engineer cannabinoid analogs for pharmaceutical evaluation. The award adds a second biosolution to the pipeline alongside NCT, expands the company’s portfolio of proprietary pharmaceutical assets, and lifts total non-dilutive funding awarded to eXoZymes and its predecessor programs to approximately $19.7 million. The two-year program begins July 1, 2026. eXoZymes Inc. is a B2i Digital Featured Company. See the company’s profile at https://b2idigital.com/exozymes-1 Michael Heltzen, CEO of eXoZymes, commented: “This is a key milestone that demonstrates our repeatable development engine of future licensing and partnering opportunities - a key feature in creating additional proprietary molecules without diluting shareholders.” From the announcement: • The grant supports work to build cannabinoid cyclase expression systems, widen the analog range, and run preclinical receptor-binding evaluation of the cannabinoid library • It arrives as the US minor cannabinoids market is forecast to grow from $11.5 billion in 2023 to $33.3 billion by 2030 See the full release: https://exozymes.com/blog/grant-cannabinoid-analogs eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
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B2iDigital
B2iDigital Jun. 23 at 8:53 PM
eXoZymes (Nasdaq: $EXOZ ) Chief Commercial Officer Damien Perriman will present at Webull’s Biotech Sector webinar on June 25, alongside Envoy Medical and IN8bio. Damien Perriman, Chief Commercial Officer of eXoZymes Inc. (Nasdaq: EXOZ), will present at Webull’s Biotech Sector webinar on June 25 at 2:00 p.m. Eastern, part of the Webull Corporate Connect series that spotlights publicly traded biotech companies for investors. eXoZymes Inc. is a B2i Digital Featured Company. See the company’s profile at https://b2idigital.com/exozymes-1 eXoZymes is a synthetic biology company that takes enzymes out of the living cell and runs them on their own to manufacture hard-to-make molecules for nutraceutical and pharmaceutical markets. The session gives investors a chance to hear directly from the company’s commercial leadership. • The webinar takes place June 25 at 2:00 p.m. Eastern, 11:00 a.m. Pacific, and registration is free with a Webull account • Perriman presents alongside Brent Lucas, Chief Executive Officer of Envoy Medical, and Will Ho, Chief Executive Officer and co-founder of IN8bio • Perriman leads commercial strategy at eXoZymes, whose cell-free platform uses AI-engineered enzymes to convert low-cost feedstocks into high-value compounds Register for the webinar: https://exozymes.com/blog/webulls-biotech-webinar-2026 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
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