Market Cap 2.25B
Revenue (ttm) 0.00
Net Income (ttm) -422.77M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,673,500
Avg Vol 2,056,296
Day's Range N/A - N/A
Shares Out 146.21M
Stochastic %K 81%
Beta 1.30
Analysts Strong Sell
Price Target $31.67

Company Profile

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Synd...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 866 8547
Address:
161 Oyster Point Boulevard, South San Francisco, United States
Winning_calls
Winning_calls Oct. 6 at 2:36 AM
$DNLI pick me up @ $15.30
0 · Reply
ninergizer
ninergizer Oct. 1 at 10:53 PM
My Top six hold for the next 6 months. $INVA$AQST $MIST $AQST $DNLI $CRNX
2 · Reply
Estimize
Estimize Sep. 29 at 11:03 AM
Wall St is expecting -0.75 EPS for $DNLI Q3 [Reporting 10/30 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
DaBullRunMasta
DaBullRunMasta Sep. 23 at 3:43 PM
$DNLI Just keep loading up on this one and wait patiently :)
1 · Reply
JessicaPies1099
JessicaPies1099 Sep. 21 at 8:48 AM
$DNLI Biotech with clinical catalyst. High volatility expected. Trading near cash value. Speculative.
0 · Reply
Drashkawisha
Drashkawisha Sep. 19 at 6:12 PM
$DNLI Denali (DNLI) is heading towards a pivotal PDUFA date on January 5, 2026, for its first-in-class drug for Hunter Syndrome. What makes this a potential game-changer is its proprietary Transport Vehicle (TV) platform, engineered to cross the blood-brain barrier and treat the severe neurological damage that current therapies cannot address. Crucially, its path to market leadership has been significantly de-risked, as its primary competitor was recently delayed by the FDA, creating a clear first-mover advantage. The FDA has already acknowledged the drug's potential with a Breakthrough Therapy designation, indicating strong regulatory support for this novel approach. An approval here is bigger than just one drug; it validates Denali's entire brain-delivery platform, unlocking massive future potential across a range of currently untreatable neurological diseases.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 5:55 PM
$DNLI Another 10% @ 13.40. Feels like fishing in a barrel.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 4:28 PM
$DNLI Let’s all hope this Beta works to the upside, too!
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 3:49 PM
$DNLI Added another 10% @ 13.515.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 3:01 PM
$DNLI Added 10% to long term position at 13.74.
0 · Reply
Latest News on DNLI
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Aug 12, 2025, 9:47 AM EDT - 7 weeks ago

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Mar 20, 2025, 2:16 PM EDT - 7 months ago

Denali Therapeutics: Vast Pipeline, First Approval Up Ahead


Why Is Denali Therapeutics Stock Trading Higher On Wednesday?

Jan 15, 2025, 2:26 PM EST - 9 months ago

Why Is Denali Therapeutics Stock Trading Higher On Wednesday?


Denali Therapeutics ALS drug fails in mid-stage trial

Jan 6, 2025, 4:43 PM EST - 9 months ago

Denali Therapeutics ALS drug fails in mid-stage trial


Denali Has A Neurodegenerative Edge Despite Market Skepticism

Nov 16, 2024, 8:56 AM EST - 11 months ago

Denali Has A Neurodegenerative Edge Despite Market Skepticism


Denali's New Summit: Changing Hunter Syndrome Landscape

Oct 2, 2023, 5:26 AM EDT - 2 years ago

Denali's New Summit: Changing Hunter Syndrome Landscape


MPS II And Beyond: Implications Of Denali's Promising Pipeline

Jul 23, 2023, 12:51 AM EDT - 2 years ago

MPS II And Beyond: Implications Of Denali's Promising Pipeline


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Jan 16, 2023, 12:15 PM EST - 2 years ago

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Winning_calls
Winning_calls Oct. 6 at 2:36 AM
$DNLI pick me up @ $15.30
0 · Reply
ninergizer
ninergizer Oct. 1 at 10:53 PM
My Top six hold for the next 6 months. $INVA$AQST $MIST $AQST $DNLI $CRNX
2 · Reply
Estimize
Estimize Sep. 29 at 11:03 AM
Wall St is expecting -0.75 EPS for $DNLI Q3 [Reporting 10/30 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
DaBullRunMasta
DaBullRunMasta Sep. 23 at 3:43 PM
$DNLI Just keep loading up on this one and wait patiently :)
1 · Reply
JessicaPies1099
JessicaPies1099 Sep. 21 at 8:48 AM
$DNLI Biotech with clinical catalyst. High volatility expected. Trading near cash value. Speculative.
0 · Reply
Drashkawisha
Drashkawisha Sep. 19 at 6:12 PM
$DNLI Denali (DNLI) is heading towards a pivotal PDUFA date on January 5, 2026, for its first-in-class drug for Hunter Syndrome. What makes this a potential game-changer is its proprietary Transport Vehicle (TV) platform, engineered to cross the blood-brain barrier and treat the severe neurological damage that current therapies cannot address. Crucially, its path to market leadership has been significantly de-risked, as its primary competitor was recently delayed by the FDA, creating a clear first-mover advantage. The FDA has already acknowledged the drug's potential with a Breakthrough Therapy designation, indicating strong regulatory support for this novel approach. An approval here is bigger than just one drug; it validates Denali's entire brain-delivery platform, unlocking massive future potential across a range of currently untreatable neurological diseases.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 5:55 PM
$DNLI Another 10% @ 13.40. Feels like fishing in a barrel.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 4:28 PM
$DNLI Let’s all hope this Beta works to the upside, too!
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 3:49 PM
$DNLI Added another 10% @ 13.515.
0 · Reply
DoctrBenway
DoctrBenway Sep. 15 at 3:01 PM
$DNLI Added 10% to long term position at 13.74.
0 · Reply
Estimize
Estimize Sep. 15 at 11:03 AM
Wall St is expecting -0.75 EPS for $DNLI Q3 [Reporting 10/30 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
marketbrent
marketbrent Sep. 15 at 8:42 AM
$DNLI Growth visibility improving if backlog and bookings hold
0 · Reply
NVDAMillionaire
NVDAMillionaire Sep. 11 at 6:39 AM
$DNLI Really good write-up that perfectly summarizes DNLI's present situation. So if you want to bring your DNLI knowledge up to date or just discover DNLI, this is required reading. https://beyondspx.com/quote/DNLI/analysis/denali-therapeutics-the-blood-brain-barrier-breakthrough-and-commercial-horizon-nasdaq-dnli
0 · Reply
DoctrBenway
DoctrBenway Sep. 10 at 7:29 PM
$DNLI If you're in or interested, the Baird call of yesterday was very informative and left me feeling very hopeful of great gains.
0 · Reply
JarvisFlow
JarvisFlow Sep. 8 at 1:21 PM
Cantor Fitzgerald updates rating for Denali Therapeutics ( $DNLI ) to Overweight.
0 · Reply
BobBijawklah
BobBijawklah Sep. 3 at 5:12 PM
$RCKT I like a few particular stocks for either thier drug being best in class or diferentiated from standard of care. I also like some stocks for FDA related delays like CRLs. So $ACHV aids in quitting nicotine with all the vaping their is potentially a bigger market for this drug than was availble for chantix. Price target 15 dollars. FDA approval date june 2026 $MIST reiceved crl replied and FDA accepted PUDFA Date Dec 2025$BMEA has been decimated by short selling and exit of ceo yet data is remarkable in Subtype of type 2 diabetes SIDD. Still have a trial in type 1 . Combo trial with ozempic that showed addtional 10% weight loss above ozempic alone. A potentiallyh best in class GLP1 drug more efficacious and safer than current approved drugs. And Nich drug BMF500 in Subtype of AML that beats standard of care hands down. $DNLI proprietry delivery system that delivers payloads across blood brain barrier FDA approval date later this year for Hunters disease . Will be best in class.
2 · Reply
Estimize
Estimize Sep. 1 at 11:06 AM
Wall St is expecting -0.75 EPS for $DNLI Q3 [Reporting 10/30 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
BobBijawklah
BobBijawklah Aug. 21 at 3:39 PM
$SRPT if you want a double bagger plus in next 9 months check out $DNLI . If you want a triple bagger in next year and half check out $RCKT . SRPT would be wise to consider aquiring $RCKT as they are in the same vertical of gene modification and also came off a patient death. But unlike srpt the death in $RCKT was due to the conditioning agent.
3 · Reply
dgbio
dgbio Aug. 19 at 9:36 PM
$DNLI It's mostly symbolic, but with Regenxbio's drug approval delayed until February, Denali could be first to market with a new Hunter drug.
0 · Reply
Quantumup
Quantumup Aug. 18 at 7:24 PM
BTIG⬇️ $STOK's PT to $28 from $29, reiterated at a Buy and said that the 36-month data for Zorevunersen (STK-001) seems to bury any remaining questions. $UCBJY $UCBJF $JAZZ $BIIB $ACAD $DNLI BTIG said in its note:
0 · Reply
JarvisFlow
JarvisFlow Aug. 18 at 1:18 PM
Morgan Stanley has updated their rating for Denali Therapeutics ( $DNLI ) to Overweight with a price target of 30.
0 · Reply
CEM97
CEM97 Aug. 13 at 5:00 PM
$DNLI came back for the VWAP at 14.34
0 · Reply