Market Cap 70.82M
Revenue (ttm) 0.00
Net Income (ttm) -20.41M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.12
Volume 471,000
Avg Vol 326,430
Day's Range N/A - N/A
Shares Out 35.95M
Stochastic %K 77%
Beta 0.10
Analysts Strong Sell
Price Target $7.86

Company Profile

Gain Therapeutics, Inc., a biotechnology company, develops novel small molecule therapeutics to treat diseases across various therapeutic areas in Switzerland, Spain, the United States, and Australia. Its drug discovery platform Magellan discovers novel allosteric binding sites in a disease; identifies proprietary small molecules that bind these sites to modulate protein function; and treats the underlying cause of the disease. The company's lead drug candidate is GT-02287, which is currently in...

Industry: Biotechnology
Sector: Healthcare
Phone: 301 500 1556
Address:
4800 Montgomery Lane, Suite 220, Bethesda, United States
Jwa68
Jwa68 Aug. 24 at 2:07 PM
$GANX My two top small biotech names continue to be, Gain and Coya $COYA. I expect both may ultimately make an important impact both on humanity and shareholders accounts. Both are likely acquisition targets over the next six months in my opinion as pharma looks for compelling CNS assets trying to backfill dwindling pipelines as the patent cliff approaches. You've all also heard the statement...follow the smart money. Ironically, both Gain and Coya represent the two smallest market cap companies by a mile in billionaire David Einhorn's own portfolio. He owns about 540K shares of Gain and about 1.6 million of Coya. When someone of his stature takes large positions in small companies like these that are clearly oit of rhe norm compared to his other holdings, there is generally a reason for it. Considering he sits on the board of the Michael J Fox Foundation, he likely has his finger on the pulse of what is encouraging in terms of addressing numerous neurodegenerative diseases. https://finance.yahoo.com/news/gain-therapeutics-ganx-top-healthcare-185925734.html
1 · Reply
microcapspeculator
microcapspeculator Aug. 24 at 1:33 PM
$GANX The ability to increase GCase is getting much more attention. I have heard GT-02287 described as better than gene therapy. Polymeric nanoparticle-mediated GBA1 gene therapy is neuroprotective in a preclinical model of Parkinson’s disease https://www.researchgate.net/publication/394800724_Polymeric_nanoparticle-mediated_GBA1_gene_therapy_is_neuroprotective_in_a_preclinical_model_of_Parkinson%27s_disease To this end, restoring GCase activity by GBA1 gene therapy would potentially benefit a broad PD population with or without the genetic risk by intervening with the natural trajectory of the disease. Remarkably, motor deficits were markedly improved, as demonstrated by grip strength, pole, and open field tests.
0 · Reply
Maximus66
Maximus66 Aug. 24 at 12:32 PM
0 · Reply
outlawinvestor1
outlawinvestor1 Aug. 23 at 10:35 PM
$GANX interesting article on potential of ambroxol, which increases GCase levels, in parkinsons. https://jamanetwork.com/journals/jamaneurology/article-abstract/2835760
2 · Reply
whodat2025
whodat2025 Aug. 23 at 8:30 PM
$GANX this week could get interesting. I’m contemplating buying an additional 500,000 shares. Common sense is really tugging on my neurons.
4 · Reply
Trade82
Trade82 Aug. 23 at 7:33 PM
$GANX is our 1b trial really like a shorter term mini phase 2 trial. The same results we are hoping for in actual patients is same as we would hope for in phase 2. Maybe even better if results seen in shorter dosing window.
1 · Reply
microcapspeculator
microcapspeculator Aug. 23 at 4:48 PM
$GANX This AD/PD info is worth reviewing. This phase 1b has potential to help validate much of the preclinical work done over the last 4 years. Thats very important to Parkinsons research. GT-02287 Parkinson’s Trial Updates: Gain Therapeutics at AD/PD 2025 https://share.google/CfLrCjPWPQp4dD5Pc Preclinical models of both GBA1-associated and idiopathic Parkinson’s disease (iPD) showed: Rescue of motor deficits and improvement in complex behaviors (e.g., nesting) Long-lasting benefits even after drug withdrawal, suggesting disease-modifying potential Reductions in key biomarkers of neurodegeneration and inflammation such as: Aggregated α-synuclein LAMP-1 (lysosomal marker) IRE-1 (ER stress marker) Miro1 (mitophagy marker) Phospho-Tau and Iba-1 These data further support GT-02287 as a next-generation therapeutic candidate with potential to modify the course of PD rather than merely treat symptoms.
0 · Reply
Madmone
Madmone Aug. 23 at 2:15 PM
$GANX Presumably cutting interest rates would make it easier to make a buyout?
1 · Reply
marvessa
marvessa Aug. 23 at 8:40 AM
$GANX above 500 Million Market Cap First Target
0 · Reply
microcapspeculator
microcapspeculator Aug. 23 at 1:05 AM
$GANX All the recent analyst reports and recent pharmexec interviews. Gain Therapeutics(GANX): Latest Analyst Reports(8/1) with Average Target of $8 https://gaintherapeutics.wordpress.com/2025/08/02/gain-therapeuticsganx-latest-analyst-reports8-1-with-average-target-of-8/ Early Trial Success Signals Promise for GT-02287 in Parkinson’s Disease Treatment https://www.pharmexec.com/view/early-trial-success-promise-gt-02287-parkinson-disease-treatment Enrollment for the Phase Ib open-label trial wrapped three months ahead of schedule, driven by growing clinician confidence in the drug’s safety and therapeutic potential. https://www.pharmexec.com/view/gain-therapeutics-ramps-next-big-step-parkinson-drug-development GT-02287 Shows Promise in Parkinson’s Patients with and Without GBA1 Mutation https://www.pharmexec.com/view/gt-02287-promise-parkinson-patients-gba1-mutation Magellan AI Identifies and Optimizes Molecules Beyond the Public Domain Future Partnership Plans for GT-02287 and the Magellan Platform in Parkinson’s Research
0 · Reply
Latest News on GANX
Gain Therapeutics Announces Proposed Public Offering

Jul 15, 2025, 4:36 PM EDT - 5 weeks ago

Gain Therapeutics Announces Proposed Public Offering


Gain Therapeutics Announces Poster Presentation at AD/PD 2025

Mar 28, 2025, 8:30 AM EDT - 5 months ago

Gain Therapeutics Announces Poster Presentation at AD/PD 2025


Gain Therapeutics Announces Oral Presentation at AD/PD 2025

Mar 6, 2025, 7:55 AM EST - 6 months ago

Gain Therapeutics Announces Oral Presentation at AD/PD 2025


Gain Therapeutics To Present At Biotech Showcase 2025

Dec 11, 2024, 8:30 AM EST - 9 months ago

Gain Therapeutics To Present At Biotech Showcase 2025


Gain Therapeutics, Inc. (GANX) Special Call Transcript

Jul 1, 2024, 10:13 AM EDT - 1 year ago

Gain Therapeutics, Inc. (GANX) Special Call Transcript


Gain Therapeutics, Inc. Appoints Gene Mack as Interim CEO

Jun 27, 2024, 4:08 PM EDT - 1 year ago

Gain Therapeutics, Inc. Appoints Gene Mack as Interim CEO


Gain Therapeutics to Present at Public Ventures Discovery Day

Mar 15, 2024, 2:30 PM EDT - 1 year ago

Gain Therapeutics to Present at Public Ventures Discovery Day


Doubling Down On Gain Therapeutics

Dec 22, 2023, 5:56 PM EST - 1 year ago

Doubling Down On Gain Therapeutics


Jwa68
Jwa68 Aug. 24 at 2:07 PM
$GANX My two top small biotech names continue to be, Gain and Coya $COYA. I expect both may ultimately make an important impact both on humanity and shareholders accounts. Both are likely acquisition targets over the next six months in my opinion as pharma looks for compelling CNS assets trying to backfill dwindling pipelines as the patent cliff approaches. You've all also heard the statement...follow the smart money. Ironically, both Gain and Coya represent the two smallest market cap companies by a mile in billionaire David Einhorn's own portfolio. He owns about 540K shares of Gain and about 1.6 million of Coya. When someone of his stature takes large positions in small companies like these that are clearly oit of rhe norm compared to his other holdings, there is generally a reason for it. Considering he sits on the board of the Michael J Fox Foundation, he likely has his finger on the pulse of what is encouraging in terms of addressing numerous neurodegenerative diseases. https://finance.yahoo.com/news/gain-therapeutics-ganx-top-healthcare-185925734.html
1 · Reply
microcapspeculator
microcapspeculator Aug. 24 at 1:33 PM
$GANX The ability to increase GCase is getting much more attention. I have heard GT-02287 described as better than gene therapy. Polymeric nanoparticle-mediated GBA1 gene therapy is neuroprotective in a preclinical model of Parkinson’s disease https://www.researchgate.net/publication/394800724_Polymeric_nanoparticle-mediated_GBA1_gene_therapy_is_neuroprotective_in_a_preclinical_model_of_Parkinson%27s_disease To this end, restoring GCase activity by GBA1 gene therapy would potentially benefit a broad PD population with or without the genetic risk by intervening with the natural trajectory of the disease. Remarkably, motor deficits were markedly improved, as demonstrated by grip strength, pole, and open field tests.
0 · Reply
Maximus66
Maximus66 Aug. 24 at 12:32 PM
0 · Reply
outlawinvestor1
outlawinvestor1 Aug. 23 at 10:35 PM
$GANX interesting article on potential of ambroxol, which increases GCase levels, in parkinsons. https://jamanetwork.com/journals/jamaneurology/article-abstract/2835760
2 · Reply
whodat2025
whodat2025 Aug. 23 at 8:30 PM
$GANX this week could get interesting. I’m contemplating buying an additional 500,000 shares. Common sense is really tugging on my neurons.
4 · Reply
Trade82
Trade82 Aug. 23 at 7:33 PM
$GANX is our 1b trial really like a shorter term mini phase 2 trial. The same results we are hoping for in actual patients is same as we would hope for in phase 2. Maybe even better if results seen in shorter dosing window.
1 · Reply
microcapspeculator
microcapspeculator Aug. 23 at 4:48 PM
$GANX This AD/PD info is worth reviewing. This phase 1b has potential to help validate much of the preclinical work done over the last 4 years. Thats very important to Parkinsons research. GT-02287 Parkinson’s Trial Updates: Gain Therapeutics at AD/PD 2025 https://share.google/CfLrCjPWPQp4dD5Pc Preclinical models of both GBA1-associated and idiopathic Parkinson’s disease (iPD) showed: Rescue of motor deficits and improvement in complex behaviors (e.g., nesting) Long-lasting benefits even after drug withdrawal, suggesting disease-modifying potential Reductions in key biomarkers of neurodegeneration and inflammation such as: Aggregated α-synuclein LAMP-1 (lysosomal marker) IRE-1 (ER stress marker) Miro1 (mitophagy marker) Phospho-Tau and Iba-1 These data further support GT-02287 as a next-generation therapeutic candidate with potential to modify the course of PD rather than merely treat symptoms.
0 · Reply
Madmone
Madmone Aug. 23 at 2:15 PM
$GANX Presumably cutting interest rates would make it easier to make a buyout?
1 · Reply
marvessa
marvessa Aug. 23 at 8:40 AM
$GANX above 500 Million Market Cap First Target
0 · Reply
microcapspeculator
microcapspeculator Aug. 23 at 1:05 AM
$GANX All the recent analyst reports and recent pharmexec interviews. Gain Therapeutics(GANX): Latest Analyst Reports(8/1) with Average Target of $8 https://gaintherapeutics.wordpress.com/2025/08/02/gain-therapeuticsganx-latest-analyst-reports8-1-with-average-target-of-8/ Early Trial Success Signals Promise for GT-02287 in Parkinson’s Disease Treatment https://www.pharmexec.com/view/early-trial-success-promise-gt-02287-parkinson-disease-treatment Enrollment for the Phase Ib open-label trial wrapped three months ahead of schedule, driven by growing clinician confidence in the drug’s safety and therapeutic potential. https://www.pharmexec.com/view/gain-therapeutics-ramps-next-big-step-parkinson-drug-development GT-02287 Shows Promise in Parkinson’s Patients with and Without GBA1 Mutation https://www.pharmexec.com/view/gt-02287-promise-parkinson-patients-gba1-mutation Magellan AI Identifies and Optimizes Molecules Beyond the Public Domain Future Partnership Plans for GT-02287 and the Magellan Platform in Parkinson’s Research
0 · Reply
The1Albatross
The1Albatross Aug. 22 at 11:38 PM
$GANX Big 2h - grabbed the .77’s but plan to avg up over here
3 · Reply
zamped1
zamped1 Aug. 22 at 8:19 PM
$GANX Very impressive 30% higher since the $1.55 offer!! "The train kepta rollin all night long." I believe the faithful here we hit this!! It will be: A DECEMBER TO REMEMBER!!!!
1 · Reply
Mstngman99
Mstngman99 Aug. 22 at 8:13 PM
$GANX Love the action the last 2 weeks. Measured offering and walk into a catalyst. Slow and steady with increasing volume.
0 · Reply
Markus_Montag
Markus_Montag Aug. 22 at 8:08 PM
$GANX Most certainly a clown but sold another 50k at 1.92 avg Total 100k shares Core position remains at 50k
5 · Reply
longhold845
longhold845 Aug. 22 at 8:03 PM
$GANX swing my SOLT gains in here... Can't get enough
0 · Reply
IwM
IwM Aug. 22 at 7:52 PM
$GANX zoom out. rounding bottom + volume shelf
1 · Reply
Dave2468999077844
Dave2468999077844 Aug. 22 at 7:07 PM
$GANX the next $ABVX ;)
0 · Reply
whodat2025
whodat2025 Aug. 22 at 6:55 PM
$GANX I say let’s take out whoever these clowns are that are selling at $1.94 and 1.95. Let’s buy up these shares and get them out of here. Obviously not big picture people.
2 · Reply
mwb1
mwb1 Aug. 22 at 6:46 PM
$GANX These last two days look to be confirmation of a technical breakout from the descending wedge. Technicals may not be as relevant in small biotech, but it still matters. Exhibit one is the classic pattern. That straight line of lower highs didn’t happen by accident. Looking good.
0 · Reply
marvessa
marvessa Aug. 22 at 4:31 PM
$GANX I want 2 digits
0 · Reply
billymike
billymike Aug. 22 at 2:50 PM
$GANX everyone have good weekend algos will play VWAP rest of day.
0 · Reply
billymike
billymike Aug. 22 at 2:45 PM
$GANX if someone takes that 5k offer we are going vertical today IMO
0 · Reply