Market Cap 1.89B
Revenue (ttm) 263.50M
Net Income (ttm) -390.98M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -148.38%
Debt to Equity Ratio 0.00
Volume 19,690,900
Avg Vol 14,711,935
Day's Range N/A - N/A
Shares Out 446.50M
Stochastic %K 57%
Beta 0.74
Analysts Sell
Price Target $7.60

Company Profile

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an int...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 260 7120
Address:
825 Industrial Road, Suite 100, San Carlos, United States
_THE_REAL_DEAL_
_THE_REAL_DEAL_ Jun. 7 at 10:25 PM
$IOVA everything is laid out to bring more value to this company, equating to a higher BO value. I hope this is the game plan going into next year. $25+ and I’ll be more than happy to have held thru the ups and downs. 💎
3 · Reply
GoldenKnightsFan
GoldenKnightsFan Jun. 7 at 9:17 PM
$IOVA This will be trading in $17-20 range next summer.
3 · Reply
mike106
mike106 Jun. 7 at 9:16 PM
$IOVA can anyone tell me how to remove stock symbol from the watchlist here on stocktwits thanks in advance
4 · Reply
beachsidefreddy
beachsidefreddy Jun. 7 at 7:34 PM
$IOVA STOCK CATCHER THOUSANDS OF PAID FOLLOWERS
0 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 5:26 PM
$IOVA Putting out info on a Sunday! My my they are ready to let it rip! https://x.com/i/status/2063660087957205400
0 · Reply
Timdriver759
Timdriver759 Jun. 7 at 5:16 PM
$IOVA According to the recent conference, the CEO stated that the lung cancer trial only requires 80 patients. Currently, with 39 patients data, the response rate is 26%. If none of the next 40 patients respond to the treatment, would the response rate still be comparable to the current second-line treatment? The FDA should have approved based on the current data already.
2 · Reply
MaximusRadius
MaximusRadius Jun. 7 at 4:57 PM
$IOVA https://youtu.be/memuTqqIG7s?si=euGT_hO5ohZ79B1K
1 · Reply
Kai_01
Kai_01 Jun. 7 at 4:15 PM
$IOVA Lexie was the first ever patient in the IOV-LUN-202 trial. She was introduced to TIL therapy by her oncologist in April 2021 and received her TIL depletion on July 10 of the same year. While it is unclear whether she is still with us, as her last post on the site was in 2022, she kindly took the time to walk us through the details of her journey. She even shared a picture of her TIL cells as they arrived at the hospital where she was treated. I strongly recommend reading through the eleven pages, even if it is emotionally difficult to process. Lexie's journey can be found here: https://forums.lungevity.org/topic/48277-moving-forward-with-the-iovance-til-trial/ 🤍
2 · Reply
JohnEss
JohnEss Jun. 7 at 3:31 PM
$IOVA I am sure many are curious about the lung cancer situation. I will share this from my Chat. I will need multiple posts to cover Can you give me deep dive on nsclc information shaping up for iova. I’ll treat this as an investor-focused clinical/regulatory deep dive: current NSCLC data, why it matters scientifically, likely development path, and what could make it valuable or disappointing. Yes. NSCLC is shaping up as the real “company-maker” indication for IOVA, much bigger than melanoma, but still with real execution/regulatory risk. Core data: Iovance reported interim IOV-LUN-202 data in previously treated advanced nonsquamous NSCLC: 25.6% ORR, 71.8% disease-control rate, 10 responses out of 39, including 2 complete responses, and median duration of response not reached after 25.4 months. That durability is the key, not just the response rate.
5 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 2:52 PM
$IOVA Former top FDA oncology regulator Marc Theoret, MD ex-Deputy Center Director of the FDA’s Oncology Center of Excellence is SVP Regulatory Strategy at Iovance (started July 2025). 15+ years reviewing oncology drugs/biologics including melanoma. Before FDA, he ran adoptive cellular therapy trials in melanoma at NCI. This isn’t a standard ex-FDA hire. This is senior leadership with direct experience on both sides of the table for complex TIL regulatory work. Materially strengthens the path for pipeline expansions and execution. Wayne doesn’t fck around!
0 · Reply
Latest News on IOVA
Iovance Biotherapeutics to Present at Upcoming Conference

May 21, 2026, 8:05 AM EDT - 17 days ago

Iovance Biotherapeutics to Present at Upcoming Conference


Iovance Biotherapeutics reports Q1 EPS (19c), consensus (15c)

2026-05-07T13:16:25.000Z - 4 weeks ago

Iovance Biotherapeutics reports Q1 EPS (19c), consensus (15c)


Iovance Biotherapeutics Earnings Call Transcript: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 weeks ago

Iovance Biotherapeutics Earnings Call Transcript: Q1 2026


Iovance Biotherapeutics Earnings release: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 weeks ago

Iovance Biotherapeutics Earnings release: Q1 2026


Iovance Biotherapeutics Quarterly report: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 weeks ago

Iovance Biotherapeutics Quarterly report: Q1 2026


Iovance Biotherapeutics Proxy statement: Proxy filing

Apr 28, 2026, 8:00 AM EDT - 5 weeks ago

Iovance Biotherapeutics Proxy statement: Proxy filing


Iovance Biotherapeutics Proxy statement: Proxy filing

Apr 28, 2026, 8:00 AM EDT - 5 weeks ago

Iovance Biotherapeutics Proxy statement: Proxy filing


Iovance Biotherapeutics Proxy statement: Proxy filing

Apr 17, 2026, 8:00 AM EDT - 7 weeks ago

Iovance Biotherapeutics Proxy statement: Proxy filing


Iovance Biotherapeutics to Present at Upcoming Conferences

Feb 26, 2026, 8:00 AM EST - 3 months ago

Iovance Biotherapeutics to Present at Upcoming Conferences


Iovance upgraded to Outperform from Market Perform at Citizens

2026-02-25T09:45:12.000Z - 3 months ago

Iovance upgraded to Outperform from Market Perform at Citizens


Iovance Biotherapeutics Earnings Call Transcript: Q4 2025

Feb 24, 2026, 8:30 AM EST - 3 months ago

Iovance Biotherapeutics Earnings Call Transcript: Q4 2025


Iovance Biotherapeutics Annual report: Q4 2025

Feb 24, 2026, 8:30 AM EST - 3 months ago

Iovance Biotherapeutics Annual report: Q4 2025


Iovance Biotherapeutics Earnings release: Q4 2025

Feb 24, 2026, 8:30 AM EST - 3 months ago

Iovance Biotherapeutics Earnings release: Q4 2025


Iovance Biotherapeutics reports Q4 EPS (18c), consensus (18c)

2026-02-24T12:19:34.000Z - 3 months ago

Iovance Biotherapeutics reports Q4 EPS (18c), consensus (18c)


Iovance Biotherapeutics Slides: Corporate presentation

Feb 24, 2026, 7:00 AM EST - 3 months ago

Iovance Biotherapeutics Slides: Corporate presentation


Iovance Biotherapeutics Slides: Corporate presentation

Jan 9, 2026, 7:00 AM EST - 5 months ago

Iovance Biotherapeutics Slides: Corporate presentation


Iovance Biotherapeutics Earnings Call Transcript: Q3 2025

Nov 6, 2025, 8:30 AM EST - 7 months ago

Iovance Biotherapeutics Earnings Call Transcript: Q3 2025


Iovance Biotherapeutics Quarterly report: Q3 2025

Nov 6, 2025, 8:30 AM EST - 7 months ago

Iovance Biotherapeutics Quarterly report: Q3 2025


Iovance Biotherapeutics Earnings release: Q3 2025

Nov 6, 2025, 8:30 AM EST - 7 months ago

Iovance Biotherapeutics Earnings release: Q3 2025


Iovance Biotherapeutics Earnings Call Transcript: Q2 2025

Aug 7, 2025, 4:30 PM EDT - 10 months ago

Iovance Biotherapeutics Earnings Call Transcript: Q2 2025


Iovance Biotherapeutics Quarterly report: Q2 2025

Aug 7, 2025, 4:30 PM EDT - 10 months ago

Iovance Biotherapeutics Quarterly report: Q2 2025


Iovance Biotherapeutics Earnings release: Q2 2025

Aug 7, 2025, 4:30 PM EDT - 10 months ago

Iovance Biotherapeutics Earnings release: Q2 2025


Iovance Biotherapeutics Appoints Marc R. Theoret, M.D.

Jul 10, 2025, 4:01 PM EDT - 11 months ago

Iovance Biotherapeutics Appoints Marc R. Theoret, M.D.


_THE_REAL_DEAL_
_THE_REAL_DEAL_ Jun. 7 at 10:25 PM
$IOVA everything is laid out to bring more value to this company, equating to a higher BO value. I hope this is the game plan going into next year. $25+ and I’ll be more than happy to have held thru the ups and downs. 💎
3 · Reply
GoldenKnightsFan
GoldenKnightsFan Jun. 7 at 9:17 PM
$IOVA This will be trading in $17-20 range next summer.
3 · Reply
mike106
mike106 Jun. 7 at 9:16 PM
$IOVA can anyone tell me how to remove stock symbol from the watchlist here on stocktwits thanks in advance
4 · Reply
beachsidefreddy
beachsidefreddy Jun. 7 at 7:34 PM
$IOVA STOCK CATCHER THOUSANDS OF PAID FOLLOWERS
0 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 5:26 PM
$IOVA Putting out info on a Sunday! My my they are ready to let it rip! https://x.com/i/status/2063660087957205400
0 · Reply
Timdriver759
Timdriver759 Jun. 7 at 5:16 PM
$IOVA According to the recent conference, the CEO stated that the lung cancer trial only requires 80 patients. Currently, with 39 patients data, the response rate is 26%. If none of the next 40 patients respond to the treatment, would the response rate still be comparable to the current second-line treatment? The FDA should have approved based on the current data already.
2 · Reply
MaximusRadius
MaximusRadius Jun. 7 at 4:57 PM
$IOVA https://youtu.be/memuTqqIG7s?si=euGT_hO5ohZ79B1K
1 · Reply
Kai_01
Kai_01 Jun. 7 at 4:15 PM
$IOVA Lexie was the first ever patient in the IOV-LUN-202 trial. She was introduced to TIL therapy by her oncologist in April 2021 and received her TIL depletion on July 10 of the same year. While it is unclear whether she is still with us, as her last post on the site was in 2022, she kindly took the time to walk us through the details of her journey. She even shared a picture of her TIL cells as they arrived at the hospital where she was treated. I strongly recommend reading through the eleven pages, even if it is emotionally difficult to process. Lexie's journey can be found here: https://forums.lungevity.org/topic/48277-moving-forward-with-the-iovance-til-trial/ 🤍
2 · Reply
JohnEss
JohnEss Jun. 7 at 3:31 PM
$IOVA I am sure many are curious about the lung cancer situation. I will share this from my Chat. I will need multiple posts to cover Can you give me deep dive on nsclc information shaping up for iova. I’ll treat this as an investor-focused clinical/regulatory deep dive: current NSCLC data, why it matters scientifically, likely development path, and what could make it valuable or disappointing. Yes. NSCLC is shaping up as the real “company-maker” indication for IOVA, much bigger than melanoma, but still with real execution/regulatory risk. Core data: Iovance reported interim IOV-LUN-202 data in previously treated advanced nonsquamous NSCLC: 25.6% ORR, 71.8% disease-control rate, 10 responses out of 39, including 2 complete responses, and median duration of response not reached after 25.4 months. That durability is the key, not just the response rate.
5 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 2:52 PM
$IOVA Former top FDA oncology regulator Marc Theoret, MD ex-Deputy Center Director of the FDA’s Oncology Center of Excellence is SVP Regulatory Strategy at Iovance (started July 2025). 15+ years reviewing oncology drugs/biologics including melanoma. Before FDA, he ran adoptive cellular therapy trials in melanoma at NCI. This isn’t a standard ex-FDA hire. This is senior leadership with direct experience on both sides of the table for complex TIL regulatory work. Materially strengthens the path for pipeline expansions and execution. Wayne doesn’t fck around!
0 · Reply
SlaveLifeAllLife
SlaveLifeAllLife Jun. 7 at 2:49 PM
$IOVA Can we talk about the NSCLC data timing? Someone posted, Fred said, It'll be in 6 months? Which scientific conference is in December 2026? ESMO Immuno-Oncology Congress Date: December 14–16, 2026 Are there other oncology conferences more fitting?
3 · Reply
beachsidefreddy
beachsidefreddy Jun. 7 at 2:21 PM
$IOVA I sent that piece about IOVA BEING NUMBER ONE TO FRIEND he passed to friend of his no bshitter says buying 20,000 shares mon am!!
0 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 1:03 PM
$IOVA Another former Replimune employee has bailed out and come on board.
1 · Reply
dogbone98
dogbone98 Jun. 7 at 12:55 PM
$IOVA To follow-up on Zydeco below, all of a sudden there are 36 positions open at IOVA, including the ones he mentioned. That has to be the highest since they purged their bogus board about a year or so ago. You can almost feel the gears shifting, especially after the Jefferies talk.
1 · Reply
BioCrazy1
BioCrazy1 Jun. 7 at 12:52 PM
$IOVA Check our this guys work experience. Marc Theoret MD Senior Vice President Regulatory Strategy Iovance Biotherapeutics
0 · Reply
Zydecoshuffle
Zydecoshuffle Jun. 7 at 11:02 AM
$IOVA ima gonna say it. On the job site at iova, two new sections appear. The first is a section for management of new BLA processes. I think it means they will be submitting more. The other section is....an AI DEPARTMENT !!!!!
2 · Reply
DGANG3
DGANG3 Jun. 7 at 10:51 AM
$IOVA For those posting about a buyout, you will need to be patient. If you have ever read a final corporate report after a company was bought, they explain how the process went in entertaining potential buyers. In most cases, it is a 6 month to 2 year process as the buyers are weeded out based on the offers and benefits to the departing admin. I am very confident that several companies have been talking to IOVA. But at this stock price, going from $4 to $40 is very unlikely over night. If all things align with our roll-outs, 2027 could be a great year. Long and Strong!
3 · Reply
Mogeyman
Mogeyman Jun. 7 at 10:39 AM
0 · Reply
cowneck_trader
cowneck_trader Jun. 7 at 12:31 AM
$IOVA Research on Tumor-Infiltrating Lymphocyte (TIL) therapy has been going on for 40 years. The groundwork for this cancer treatment began in the mid-1980s. The History of TIL Research 1986 (The Discovery): Dr. Steven Rosenberg and his team at the National Cancer Institute discovered TILs. They found these special immune cells inside human tumors and figured out how to grow them in a lab. 1988 (The First Trials): Dr. Rosenberg led the very first clinical trials. He proved that infusing these grown immune cells back into patients could shrink advanced cancer tumors. 2024 (The FDA Approval): After decades of testing and perfecting the process, the U.S. Food and Drug Administration approved the very first TIL therapy, called Amtagvi (lifileucel), to treat advanced melanoma.
2 · Reply
MysticChartReaderIQ69
MysticChartReaderIQ69 Jun. 7 at 12:06 AM
$IOVA 20billon buyout
4 · Reply
Hero2Zero
Hero2Zero Jun. 6 at 11:59 PM
$IOVA now consistently selling weekly covered calls at $5 and caught a bid on the 6/18 weekly $5.50 contracts this past week. My recommendation is to ignore those underwater from buying the approval pump (think we still have some around here who bought the COVID pump which is wild). Price is clearly in a prolonged uptrend. Look at the 1 year chart then start zooming out. Trend is now our friend. On the longer time frame you can see volatility has cooled quite a bit. Should get more and more pleasant to own this name.
0 · Reply
Flyingkitty
Flyingkitty Jun. 6 at 11:44 PM
$IOVA So we are going to combo with these drug peeps ... Food for thought 🤔........Analysts currently project that Keytruda sales in 2027 will likely be in the range of $32–34 billion globally, making it one of the highest-selling drugs in the world. Most forecasts show continued growth through 2027 before the major patent cliff begins around 2028–2029. Some recent projections and commentary: Evaluate Pharma projects Keytruda sales peaking near $32.7 billion in 2026, with growth continuing into 2027–2028. Analysts cited in 2025–2026 industry reports estimate a peak around $33–34 billion annually before biosimilar competition starts reducing revenue after patent expiration. Merck’s quarterly 2026 results continue to show strong momentum, with Keytruda growing about 12% year-over-year and already generating over $8 billion per quarter. A reasonable Wall Street consensus estimate for 2027 is therefore approximate 38 Billion
1 · Reply