Market Cap 970.29M
Revenue (ttm) 131.16M
Net Income (ttm) -95.50M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -72.81%
Debt to Equity Ratio 0.00
Volume 849,000
Avg Vol 2,755,076
Day's Range N/A - N/A
Shares Out 102.68M
Stochastic %K 57%
Beta -1.27
Analysts Strong Sell
Price Target $22.25

Company Profile

Day One Biopharmaceuticals, Inc., a commercial-stage company, focused on advancing class medicines for childhood and adult diseases with equal intensity in the United States. The company's lead product candidate is tovorafenib, an oral brain-penetrant type II pan-rapidly accelerated fibrosarcoma kinase inhibitor that is in Phase II clinical trial for pediatric patients with relapsed or refractory low-grade glioma; and Ipsen, a frontline raf-altered pLGG which is in Phase III clinical trial stage...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 484 0899
Address:
1800 Sierra Point Parkway, Suite 200, Brisbane, United States
GeniusLoci
GeniusLoci Dec. 27 at 7:45 PM
$SNDX $URGN $DAWN $IOVA $AUTL Previous acquisition holdings: CTIC, ITCI, BPMC, YMAB and SCPH Presently, my money is on the following M&A prospects: SNDX, URGN, DAWN, IOVA and AUTL
2 · Reply
StatutoryS
StatutoryS Dec. 27 at 9:39 AM
$DAWN Risk tolerance remains selective and tied closely to execution credibility. Operational cadence needs to tighten meaningfully. Transparency improvements could narrow valuation spreads. Compounding requires operational consistency.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 24 at 8:02 PM
Commercial-stage oncology focused bios winners & losers YTD FY2025. We count 6 M&A exits between March & September 2025 (highlighted in green). It's been quiet since. There was no M&A in this specific peer group for 6 months the prior year between 9/1/24 & 2/28/25. This is not investment advice. $KPTI is a textbook example of why shareholders are usually penalized for those that do not sell within 2 years of FDA approval. $NUVB has been the best performing stock in this peer group YTD. We suspect NUVB (with URGN & SNDX) will sell by mid-2026. It will be 2 years since TIL was first approved for $IOVA on 2/16/26. IOVA has finally started to recover after a brutal FY2025. $DAWN is next to hit 2 years on 4/23/26 (tied with IBRX). $AUTL ?
5 · Reply
AllusionAlpha
AllusionAlpha Dec. 24 at 11:54 AM
$DAWN Future price discovery depends on how timelines compress uncertainty rather than extend speculation. Inconsistent delivery may prolong volatility.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 23 at 2:09 PM
$SNDX & $DAWN are both commercial-stage oncology focused bios. Their FDA approved medicines target different cancers. Last week DAWN surged 20%+ over 2 days after trading patterns suggested DAWN may, again may, be in active M&A negotiations. This is not investment advice. We have no idea what will happen to the share price of either bio in FY2026. It is interesting to see how the DAWN speculation manifests in call option trading. DAWN has recently traded for around $10 a share while SNDX just over $20. If you were to buy 1/16/26 calls with strike prices 50% higher than recent averages ($15 for DAWN & $30 for SNDX), and the bio was acquired for 33% more than the call option strike price (DAWN for $20/share & SNDX for $40), the DAWN return would be 525% or 5.25 to 1 where the return for SNDX would be 7,600% or 76 to 1. We're only sharing observations. 85% of stock options expire worthless $XBI $IBB $NBI
2 · Reply
Doozio
Doozio Dec. 22 at 10:29 PM
A new 🧠 $DAWN ENTA 🐒🍌🧠⏰♾️
0 · Reply
Doozio
Doozio Dec. 22 at 10:18 PM
Wen a new 🧠 $DAWN is $ENTA 🐒🍌🧠⏰♾️
0 · Reply
TheMach99
TheMach99 Dec. 22 at 4:25 PM
$DAWN speculation May be the Mersana deal is linked to Ipsen's interest in ADCs https://www.fiercebiotech.com/biotech/ipsen-continues-adc-push-1b-deal-simceres-preclinical-lrrc15-targeting-asset
1 · Reply
WallStJesus
WallStJesus Dec. 22 at 3:02 PM
$DAWN Put/Call: 58/1681
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 21 at 6:32 PM
Updated schedule of what's happened to the share prices of all 61 new commercial-stage oncology focused bios since 1/1/13 (v. share prices @ FDA approval). The biggest take-aways? 1. Only 7 of the 32 still independent trade at higher share prices today. That's not a typo...only 7 of 32. 2. 17 were sold at meaningful gains for shareholders. 15 of these 17 were sold within 2 years of FDA approval. 3. 9 of the 61 were sold at big losses. 8 of the 9 waited for over 2 years to sell. 4. 3 of the 61 went bankrupt 5. Had you purchased $1,000 worth of stock at the time of approval in all 61 bios, your $61,000 investment would be worth $60,103 today. Remember, 95 to 98% of new cancer drugs in Phase 1 trials are never approved. This is why 95% of clinical-stage bios fail & probably why those that wait to sell result in losses for shareholders. $NUVB is the best performing stock in this peer group to date. For $IOVA 2 years comes 2/16/26, $DAWN 4/23/26 & SNDX 8/14/26 ​Will $IMCR & $URGN be outliers?
Latest News on DAWN
Day One Biopharmaceuticals: Sales Figures In The Crosshairs

Dec 25, 2024, 7:31 AM EST - 1 year ago

Day One Biopharmaceuticals: Sales Figures In The Crosshairs


Diving Into Day One Biopharmaceuticals

Jul 23, 2023, 4:43 AM EDT - 2 years ago

Diving Into Day One Biopharmaceuticals


Day One Announces Pricing of Public Offering of Common Stock

Jun 6, 2023, 10:31 PM EDT - 2 years ago

Day One Announces Pricing of Public Offering of Common Stock


GeniusLoci
GeniusLoci Dec. 27 at 7:45 PM
$SNDX $URGN $DAWN $IOVA $AUTL Previous acquisition holdings: CTIC, ITCI, BPMC, YMAB and SCPH Presently, my money is on the following M&A prospects: SNDX, URGN, DAWN, IOVA and AUTL
2 · Reply
StatutoryS
StatutoryS Dec. 27 at 9:39 AM
$DAWN Risk tolerance remains selective and tied closely to execution credibility. Operational cadence needs to tighten meaningfully. Transparency improvements could narrow valuation spreads. Compounding requires operational consistency.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 24 at 8:02 PM
Commercial-stage oncology focused bios winners & losers YTD FY2025. We count 6 M&A exits between March & September 2025 (highlighted in green). It's been quiet since. There was no M&A in this specific peer group for 6 months the prior year between 9/1/24 & 2/28/25. This is not investment advice. $KPTI is a textbook example of why shareholders are usually penalized for those that do not sell within 2 years of FDA approval. $NUVB has been the best performing stock in this peer group YTD. We suspect NUVB (with URGN & SNDX) will sell by mid-2026. It will be 2 years since TIL was first approved for $IOVA on 2/16/26. IOVA has finally started to recover after a brutal FY2025. $DAWN is next to hit 2 years on 4/23/26 (tied with IBRX). $AUTL ?
5 · Reply
AllusionAlpha
AllusionAlpha Dec. 24 at 11:54 AM
$DAWN Future price discovery depends on how timelines compress uncertainty rather than extend speculation. Inconsistent delivery may prolong volatility.
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 23 at 2:09 PM
$SNDX & $DAWN are both commercial-stage oncology focused bios. Their FDA approved medicines target different cancers. Last week DAWN surged 20%+ over 2 days after trading patterns suggested DAWN may, again may, be in active M&A negotiations. This is not investment advice. We have no idea what will happen to the share price of either bio in FY2026. It is interesting to see how the DAWN speculation manifests in call option trading. DAWN has recently traded for around $10 a share while SNDX just over $20. If you were to buy 1/16/26 calls with strike prices 50% higher than recent averages ($15 for DAWN & $30 for SNDX), and the bio was acquired for 33% more than the call option strike price (DAWN for $20/share & SNDX for $40), the DAWN return would be 525% or 5.25 to 1 where the return for SNDX would be 7,600% or 76 to 1. We're only sharing observations. 85% of stock options expire worthless $XBI $IBB $NBI
2 · Reply
Doozio
Doozio Dec. 22 at 10:29 PM
A new 🧠 $DAWN ENTA 🐒🍌🧠⏰♾️
0 · Reply
Doozio
Doozio Dec. 22 at 10:18 PM
Wen a new 🧠 $DAWN is $ENTA 🐒🍌🧠⏰♾️
0 · Reply
TheMach99
TheMach99 Dec. 22 at 4:25 PM
$DAWN speculation May be the Mersana deal is linked to Ipsen's interest in ADCs https://www.fiercebiotech.com/biotech/ipsen-continues-adc-push-1b-deal-simceres-preclinical-lrrc15-targeting-asset
1 · Reply
WallStJesus
WallStJesus Dec. 22 at 3:02 PM
$DAWN Put/Call: 58/1681
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Dec. 21 at 6:32 PM
Updated schedule of what's happened to the share prices of all 61 new commercial-stage oncology focused bios since 1/1/13 (v. share prices @ FDA approval). The biggest take-aways? 1. Only 7 of the 32 still independent trade at higher share prices today. That's not a typo...only 7 of 32. 2. 17 were sold at meaningful gains for shareholders. 15 of these 17 were sold within 2 years of FDA approval. 3. 9 of the 61 were sold at big losses. 8 of the 9 waited for over 2 years to sell. 4. 3 of the 61 went bankrupt 5. Had you purchased $1,000 worth of stock at the time of approval in all 61 bios, your $61,000 investment would be worth $60,103 today. Remember, 95 to 98% of new cancer drugs in Phase 1 trials are never approved. This is why 95% of clinical-stage bios fail & probably why those that wait to sell result in losses for shareholders. $NUVB is the best performing stock in this peer group to date. For $IOVA 2 years comes 2/16/26, $DAWN 4/23/26 & SNDX 8/14/26 ​Will $IMCR & $URGN be outliers?
Xanderzzzzzzz
Xanderzzzzzzz Dec. 20 at 5:02 PM
$DAWN To gain access to clinical stage ADC - a much-hyped approach to treating cancer that is essentially a more targeted form of chemotherapy - feels like good business from a mgmt team led by Jeremy Bender, Ph.D., MBA who formerly worked at Gilead and has also been COO at Tizona, and CBO at Sutro (STRO). Furthermore, DAWN has a partnership in place with Ipsen, granting rights to market and sell Ojemda ex-US in exchange for a ~$71M-FRONT investment, $40M equity investment, up to ~$380M in commercial launch and sales-based milestone pymts, and mid-teens % royalties on net sales. Overall, what I find most impressive about DAWN is its execution - first securing accelerated approval for Ojemda, and priority review voucher, sold for $108M last quarter, and also with its slick deal-making and partnering. Besides CEO , CMO Elly Barry M.D. was formerly Global Clinical Lead for Pediatric Oncology at PFE, while CSO & Head of R&D were both formerly at Immunogen acquired by ABBV for @$10BN in '24
0 · Reply
Xanderzzzzzzz
Xanderzzzzzzz Dec. 20 at 4:52 PM
0 · Reply
Bio_Invest101
Bio_Invest101 Dec. 19 at 9:18 PM
$DAWN could not understand the big 15% trend up with 5.18M shares high volumes yesterday and similar 5.3 M volumes down 7% today. But all 5 days this week traded from low 3.5 M to 5.4 M shares Interesting week
0 · Reply
Bio_Invest101
Bio_Invest101 Dec. 19 at 10:25 AM
$DAWN Just feel like we’re not done yet from 14-17% strong uptrend moves in double volumes without news yesterday and possibly lasting into Jeremy’s appearance on 1/12 at JPM Healthcare Conference in line with the MRSN deal closing by end of Jan. https://www.cnbc.com/2025/12/18/friday-could-be-a-wild-day-of-trading-on-wall-street-heres-why.html https://stocks.apple.com/AG6REK4bQQEuFkVOS88p6wg
0 · Reply
TheGunnerAB
TheGunnerAB Dec. 18 at 10:53 PM
$DAWN There were a couple of risk reversals today as well. They rolled from December to January and sold April $9 puts to finance the roll. 1,000 calls were rolled in two batches of 500 the same with the April $9 puts.
0 · Reply
ShortsHater
ShortsHater Dec. 18 at 5:46 PM
$BCRX will recover like $FOLD and $DAWN , check out their 6 month chart. Takes time, need patience
1 · Reply
Bio_Invest101
Bio_Invest101 Dec. 18 at 4:56 PM
$DAWN 3.1 Million shares traded 17% upward b4 noon. What will happen on triple Witch Day tomorrow and JPM CC in 2 weeks? Seems some people pro active with convictions
0 · Reply
RonIsWrong
RonIsWrong Dec. 18 at 4:35 PM
$DAWN 👀 strength yesterday. bunch of dark pool trades came in last few days. big move today on unusual option activity at the open.
0 · Reply
Doozio
Doozio Dec. 18 at 3:53 PM
$FBRX about it. A new 🧠 $DAWN is 🐒🍌🧠⏰♾️. N it hasn’t even spread on the $DLO yet.
0 · Reply
YouVSYou
YouVSYou Dec. 18 at 3:35 PM
$DAWN 🎯
0 · Reply
RonIsWrong
RonIsWrong Dec. 18 at 3:19 PM
$DAWN Unusual options activity (I did bite on some April $10 calls 10 days ago)
2 · Reply
BobJoeDud
BobJoeDud Dec. 18 at 3:17 PM
$DAWN Who is buying them and for how much? Only thing I can think of for the spike.
0 · Reply