Market Cap 9.84B
Revenue (ttm) 0.00
Net Income (ttm) -303.27M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 382,900
Avg Vol 387,144
Day's Range N/A - N/A
Shares Out 27.92M
Stochastic %K 27%
Beta 2.76
Analysts Strong Sell
Price Target $636.84

Company Profile

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide. It also develops ulixacaltamide, a small molec...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 300 8460
Address:
99 High Street, 30th Floor, Boston, United States
Trainguy1
Trainguy1 Sep. 7 at 4:00 PM
$PRAX After late-stage clinical failures cleared out Ulixacaltamide’s closest oral pipeline rivals: Jazz Pharmaceuticals’ Suvecaltamide and Sage Therapeutics’ SAGE-324, Ulixacaltamide’s current market competition consists of lower efficacy generic drugs, neurostimulation devices, and early-stage pipeline assets.
1 · Reply
Trainguy1
Trainguy1 Sep. 7 at 3:12 PM
$PRAX In the USA, 1 to 2 million out of the 7 to 10 million people who experience essential tremor use the beta blocker Propranolol. Praxis’s upcoming calcium channel inhibitor drug, Ulixacaltamide, if approved (PDUFA date Jan29, 2027) can be used on a stand-alone basis or as a combo drug with Propranolol to treat essential tremor. When used as a combo therapy, patients achieved a mean change of -1.07 on the modified Activities of Daily Living (mADL11) scale at week 8, compared to -0.61 for patients on propranolol and a placebo. At week 8, 48% of combo therapy patients achieved a clinically meaningful improvement, versus 25% of patients taking propranolol with a placebo. Propranolol is effective in 50% to 60% of patients who try it. About 10% to 15% of people who initially respond well to Propranolol will develop a drug tolerance after a year or more of use, requiring a prescription change.
0 · Reply
R84877P
R84877P Sep. 1 at 9:10 PM
$PRAX Ready for $400 already....
0 · Reply
Trainguy1
Trainguy1 Sep. 1 at 3:49 PM
$PRAX Praxis’s Relutrigine (PRAX-562) is an oral small molecule drug intended to treat developmental epileptic encephalopathies (DEEs) caused by SCN2A & SCN8A gene mutations. Relutrigine inhibits persistent sodium current channels. An NDA for the drug is currently being evaluated by the FDA, and is expected to be approved on or near Dec 27, 2026. Relutrigine’s principal competitor is Neurocrine (drug NBI-355), developed by Xenon Pharma. NBI-355 is currently undergoing a ph1b clinical trial. Data from the trial should be presented around the end of 2026.
0 · Reply
Brianum2011
Brianum2011 Aug. 31 at 8:02 PM
0 · Reply
FactsPlease99
FactsPlease99 Aug. 31 at 12:36 PM
$XENE $BHVN $PRAX its gonna be battle with a crowded market with XENE, Biohaven, SK, and also Longboard! Doctors will be so bombarded and overwhelmed on Focal seizure treatments...basicaly all good seizure outcomes... Xenon and bio haven no titration is a big advantage and seizure freedom LT seems good for both. Xenon the soonest approval...Oh now let's throw in Praxis for some more fun!! dammmmm thats a lot of choices. 5 new drugs for Focal....
0 · Reply
topstockalerts
topstockalerts Aug. 31 at 12:13 PM
Pre Market Top Gainers PT2 $NCRA $LGPS $COOT $WBUY $PRAX
0 · Reply
gerryh57
gerryh57 Aug. 28 at 6:10 PM
$PRAX kind of love this, while I am upside down today, I can easily see this being my best investment of the year. Perspective total market volume 140,000 shares both buyers and sellers so 70,000 shares may have made me quite a bit….. took a bit to type that you know essential tremors and all
1 · Reply
R84877P
R84877P Aug. 28 at 4:28 PM
$PRAX This is a STEAL! buying discount
0 · Reply
glaucio
glaucio Aug. 28 at 4:07 PM
$PRAX we are safe , as as it keeps floating above $300
0 · Reply
Latest News on PRAX
Praxis Precision Medicines Earnings Call Transcript: Q2 2026

Aug 6, 2026, 8:30 AM EDT - 4 weeks ago

Praxis Precision Medicines Earnings Call Transcript: Q2 2026


Praxis Precision Medicines Earnings release: Q2 2026

Aug 6, 2026, 8:30 AM EDT - 4 weeks ago

Praxis Precision Medicines Earnings release: Q2 2026


Praxis Precision Medicines Quarterly report: Q2 2026

Aug 6, 2026, 8:30 AM EDT - 4 weeks ago

Praxis Precision Medicines Quarterly report: Q2 2026


Praxis Precision Medicines Slides: Corporate presentation

Aug 6, 2026, 8:30 AM EDT - 4 weeks ago

Praxis Precision Medicines Slides: Corporate presentation


Praxis Precision initiated with a Buy at Goldman Sachs

2026-07-13T09:25:04.000Z - 1 month ago

Praxis Precision initiated with a Buy at Goldman Sachs


Praxis Precision initiated with an Outperform at RBC Capital

2026-06-17T20:37:28.000Z - 2 months ago

Praxis Precision initiated with an Outperform at RBC Capital


Praxis Precision Medicines Transcript: AGM 2026

Jun 10, 2026, 9:00 AM EDT - 3 months ago

Praxis Precision Medicines Transcript: AGM 2026


Praxis Precision falls -15.4%

2026-06-02T16:19:35.000Z - 3 months ago

Praxis Precision falls -15.4%


Praxis Precision price target lowered to $810 from $843 at BTIG

2026-06-02T11:42:18.000Z - 3 months ago

Praxis Precision price target lowered to $810 from $843 at BTIG


Praxis Precision Medicines Provides Vormatrigine Program Update

Jun 1, 2026, 4:15 PM EDT - 3 months ago

Praxis Precision Medicines Provides Vormatrigine Program Update


Praxis Precision Medicines Earnings Call Transcript: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 months ago

Praxis Precision Medicines Earnings Call Transcript: Q1 2026


Praxis Precision Medicines Earnings release: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 months ago

Praxis Precision Medicines Earnings release: Q1 2026


Praxis Precision Medicines Quarterly report: Q1 2026

May 7, 2026, 8:30 AM EDT - 4 months ago

Praxis Precision Medicines Quarterly report: Q1 2026


Praxis Precision Medicines Slides: Corporate presentation

May 7, 2026, 7:00 AM EDT - 4 months ago

Praxis Precision Medicines Slides: Corporate presentation


Praxis Precision Medicines Proxy statement: Proxy filing

Apr 30, 2026, 8:00 AM EDT - 4 months ago

Praxis Precision Medicines Proxy statement: Proxy filing


Praxis Precision Medicines Proxy statement: Proxy filing

Apr 30, 2026, 8:00 AM EDT - 4 months ago

Praxis Precision Medicines Proxy statement: Proxy filing


Praxis Precision Medicines Earnings Call Transcript: Q4 2025

Feb 19, 2026, 8:00 AM EST - 6 months ago

Praxis Precision Medicines Earnings Call Transcript: Q4 2025


Praxis Precision Medicines Earnings release: Q4 2025

Feb 19, 2026, 8:00 AM EST - 6 months ago

Praxis Precision Medicines Earnings release: Q4 2025


Praxis Precision Medicines Annual report: Q4 2025

Feb 19, 2026, 8:00 AM EST - 6 months ago

Praxis Precision Medicines Annual report: Q4 2025


Praxis Precision Medicines Slides: Corporate presentation

Feb 19, 2026, 7:00 AM EST - 6 months ago

Praxis Precision Medicines Slides: Corporate presentation


Praxis Precision Medicines Slides: Corporate presentation

Jan 12, 2026, 7:00 AM EST - 8 months ago

Praxis Precision Medicines Slides: Corporate presentation


Praxis Precision Medicines Transcript: Fireside Chat

Nov 24, 2025, 1:00 PM EST - 9 months ago

Praxis Precision Medicines Transcript: Fireside Chat


Praxis Precision Medicines Slides: Corporate Presentation

Nov 10, 2025, 7:00 AM EST - 10 months ago

Praxis Precision Medicines Slides: Corporate Presentation


Praxis Precision Medicines Transcript: Fireside Chat

Nov 7, 2025, 12:30 PM EST - 10 months ago

Praxis Precision Medicines Transcript: Fireside Chat


Praxis Precision Medicines Earnings release: Q3 2025

Nov 5, 2025, 8:00 AM EST - 10 months ago

Praxis Precision Medicines Earnings release: Q3 2025


Praxis Precision Medicines Quarterly report: Q3 2025

Nov 5, 2025, 8:00 AM EST - 10 months ago

Praxis Precision Medicines Quarterly report: Q3 2025


What's fueling PRAX stock's jaw-dropping 235% surge on Thursday?

Oct 16, 2025, 12:02 PM EDT - 10 months ago

What's fueling PRAX stock's jaw-dropping 235% surge on Thursday?


Praxis Precision Medicines Transcript: Study Result

Oct 16, 2025, 8:00 AM EDT - 10 months ago

Praxis Precision Medicines Transcript: Study Result


Praxis Precision Medicines Press release: Study Result

Oct 16, 2025, 8:00 AM EDT - 10 months ago

Praxis Precision Medicines Press release: Study Result


Praxis Precision Medicines Slides: Study Result

Oct 16, 2025, 8:00 AM EDT - 10 months ago

Praxis Precision Medicines Slides: Study Result


Praxis Precision Medicines Transcript: Fireside Chat

Aug 7, 2025, 11:00 AM EDT - 1 year ago

Praxis Precision Medicines Transcript: Fireside Chat


Praxis Precision Medicines Transcript: Fireside Chat

Aug 5, 2025, 10:00 AM EDT - 1 year ago

Praxis Precision Medicines Transcript: Fireside Chat


Praxis Precision Medicines Slides: Fireside Chat

Aug 5, 2025, 10:00 AM EDT - 1 year ago

Praxis Precision Medicines Slides: Fireside Chat


Praxis Precision Medicines Earnings Call Transcript: Q2 2025

Aug 4, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Earnings Call Transcript: Q2 2025


Praxis Precision Medicines Quarterly report: Q2 2025

Aug 4, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Quarterly report: Q2 2025


Praxis Precision Medicines Earnings release: Q2 2025

Aug 4, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Earnings release: Q2 2025


Praxis Precision Medicines Slides: Q2 2025

Aug 4, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Slides: Q2 2025


Praxis Precision Medicines Slides: Corporate Presentation

Aug 3, 2025, 5:00 PM EDT - 1 year ago

Praxis Precision Medicines Slides: Corporate Presentation


Praxis Precision Medicines Transcript: Status Update

May 2, 2025, 10:00 AM EDT - 1 year ago

Praxis Precision Medicines Transcript: Status Update


Praxis Precision Medicines Press release: Status Update

May 2, 2025, 10:00 AM EDT - 1 year ago

Praxis Precision Medicines Press release: Status Update


Praxis Precision Medicines Slides: Status Update

May 2, 2025, 10:00 AM EDT - 1 year ago

Praxis Precision Medicines Slides: Status Update


Praxis Precision Medicines Quarterly report: Q1 2025

May 2, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Quarterly report: Q1 2025


Praxis Precision Medicines Earnings release: Q1 2025

May 2, 2025, 8:30 AM EDT - 1 year ago

Praxis Precision Medicines Earnings release: Q1 2025


Praxis Precision Medicines Proxy statement: Proxy Filing

Apr 30, 2025, 8:00 AM EDT - 1 year ago

Praxis Precision Medicines Proxy statement: Proxy Filing


Praxis Precision Medicines Proxy statement: Proxy Filing

Apr 30, 2025, 8:00 AM EDT - 1 year ago

Praxis Precision Medicines Proxy statement: Proxy Filing


Praxis Precision Medicines Earnings release: Q4 2024

Feb 28, 2025, 9:30 AM EST - 1 year ago

Praxis Precision Medicines Earnings release: Q4 2024


Praxis Precision Medicines Annual report: Q4 2024

Feb 28, 2025, 9:30 AM EST - 1 year ago

Praxis Precision Medicines Annual report: Q4 2024


Trainguy1
Trainguy1 Sep. 7 at 4:00 PM
$PRAX After late-stage clinical failures cleared out Ulixacaltamide’s closest oral pipeline rivals: Jazz Pharmaceuticals’ Suvecaltamide and Sage Therapeutics’ SAGE-324, Ulixacaltamide’s current market competition consists of lower efficacy generic drugs, neurostimulation devices, and early-stage pipeline assets.
1 · Reply
Trainguy1
Trainguy1 Sep. 7 at 3:12 PM
$PRAX In the USA, 1 to 2 million out of the 7 to 10 million people who experience essential tremor use the beta blocker Propranolol. Praxis’s upcoming calcium channel inhibitor drug, Ulixacaltamide, if approved (PDUFA date Jan29, 2027) can be used on a stand-alone basis or as a combo drug with Propranolol to treat essential tremor. When used as a combo therapy, patients achieved a mean change of -1.07 on the modified Activities of Daily Living (mADL11) scale at week 8, compared to -0.61 for patients on propranolol and a placebo. At week 8, 48% of combo therapy patients achieved a clinically meaningful improvement, versus 25% of patients taking propranolol with a placebo. Propranolol is effective in 50% to 60% of patients who try it. About 10% to 15% of people who initially respond well to Propranolol will develop a drug tolerance after a year or more of use, requiring a prescription change.
0 · Reply
R84877P
R84877P Sep. 1 at 9:10 PM
$PRAX Ready for $400 already....
0 · Reply
Trainguy1
Trainguy1 Sep. 1 at 3:49 PM
$PRAX Praxis’s Relutrigine (PRAX-562) is an oral small molecule drug intended to treat developmental epileptic encephalopathies (DEEs) caused by SCN2A & SCN8A gene mutations. Relutrigine inhibits persistent sodium current channels. An NDA for the drug is currently being evaluated by the FDA, and is expected to be approved on or near Dec 27, 2026. Relutrigine’s principal competitor is Neurocrine (drug NBI-355), developed by Xenon Pharma. NBI-355 is currently undergoing a ph1b clinical trial. Data from the trial should be presented around the end of 2026.
0 · Reply
Brianum2011
Brianum2011 Aug. 31 at 8:02 PM
0 · Reply
FactsPlease99
FactsPlease99 Aug. 31 at 12:36 PM
$XENE $BHVN $PRAX its gonna be battle with a crowded market with XENE, Biohaven, SK, and also Longboard! Doctors will be so bombarded and overwhelmed on Focal seizure treatments...basicaly all good seizure outcomes... Xenon and bio haven no titration is a big advantage and seizure freedom LT seems good for both. Xenon the soonest approval...Oh now let's throw in Praxis for some more fun!! dammmmm thats a lot of choices. 5 new drugs for Focal....
0 · Reply
topstockalerts
topstockalerts Aug. 31 at 12:13 PM
Pre Market Top Gainers PT2 $NCRA $LGPS $COOT $WBUY $PRAX
0 · Reply
gerryh57
gerryh57 Aug. 28 at 6:10 PM
$PRAX kind of love this, while I am upside down today, I can easily see this being my best investment of the year. Perspective total market volume 140,000 shares both buyers and sellers so 70,000 shares may have made me quite a bit….. took a bit to type that you know essential tremors and all
1 · Reply
R84877P
R84877P Aug. 28 at 4:28 PM
$PRAX This is a STEAL! buying discount
0 · Reply
glaucio
glaucio Aug. 28 at 4:07 PM
$PRAX we are safe , as as it keeps floating above $300
0 · Reply
Trainguy1
Trainguy1 Aug. 24 at 3:33 PM
$PRAX This graphic shows PRAX's forecasted peak sales projections for their products that have passed or are undergoing ph3 trials. You can see these add up to $20 billion/yr. If PRAX were to be acquired, Google AI says you can estimate the acquisition price as follows: To estimate a central nervous system (CNS) biotech company's acquisition price, multiply its projected peak sales by a valuation multiple of 3.5x to 5.5x for Phase 3 assets (or 2.0x to 3.5x if still in early Phase 3 with high regulatory risk), then adjust for net cash and probability of success. You do the math.
2 · Reply
JFDI
JFDI Aug. 21 at 2:30 PM
$PRAX thin 2 in
0 · Reply
Trainguy1
Trainguy1 Aug. 21 at 12:49 PM
$PRAX I appreciate the highly ranked women of Wall Street who analyze Praxis. Look at these analysts rankings and their 1-year share price forecasts. They tell us to anticipate share price growth of at least 40%. I trust that my investment in PRAX will grow to at least match the low-end forecast, and will very likely surpass it. * Ritu Baral, ranked #55 of 12,492. 1 yr PRAX share price forecast: $510/sh * Ami Fadia, ranked #78 of 12,492. 1 yr PRAX share price forecast: $582 * Yasmeen Rahimi, ranked #156 of 12,489. 1 yr PRAX share price forecast: $1200
0 · Reply
AngusMacbeth
AngusMacbeth Aug. 20 at 5:26 PM
$PRAX Adding a few today. When those FDA approvals come in folks will wish they bought here.
1 · Reply
Brianum2011
Brianum2011 Aug. 19 at 10:52 PM
0 · Reply
R84877P
R84877P Aug. 19 at 7:40 PM
$PRAX Flying high
0 · Reply
Quantumup
Quantumup Aug. 17 at 1:04 PM
Raymond James⬆️ $RAPP's PT to $75, reiterated Strong Buy and said -- We believe RAP-219's bipolar mania readout is one of the most asymmetric catalysts in SMID biotech. $XENE $PRAX OVID ESAIY BHVN Here's what Raymond James went on to say: https://x.com/Quantumup1/status/2089337204015276259?s=20
0 · Reply
Quantumup
Quantumup Aug. 17 at 10:35 AM
Raymond James⬆️ $PRAX's PT to $945, reiterated Strong Buy and said -- The next 6-12 months for Praxis represent one of the most compelling setups in SMID biotech. $JAZZ $UCBJY RAPP XENE ESAIY BHVN OVID Here's what else Raymond James had to say: https://x.com/Quantumup1/status/2089299818636054544?s=20
0 · Reply
JodieChristy
JodieChristy Aug. 7 at 9:46 PM
Biotech Valuation Overload? My Top 4 High-Conviction Value Picks To Outsmart The Market! $INSM is trading strong around $131.10 right now! $PTGX is trading strong around $146.00 right now! $BBIO is trading strong around $84.48 right now! $PRAX is trading strong around $360.76 right now! While the broader biotech sector looks insanely overvalued, I filter strictly for late-stage clinical or early commercial winners featuring elite management, massive broad pipelines, $10B+ peak sales potential, and prices at or below intrinsic value. My current high-conviction watchlist features exactly four names: $INSM,$PTGX, $BBIO, and$PRAX.[Live Trading Strategy]: Avoid chasing overpriced hype scale into key support levels methodically and let value do the heavy lifting!
3 · Reply
Trainguy1
Trainguy1 Aug. 7 at 5:15 PM
$PRAX Clinical & Pipeline Milestones — Q4 2026: Topline data expected from the EMERALD trial for relutrigine in broad DEEs. Late 2026 / 2027: Amended study designs and progress updates for the vormatrigine epilepsy program following initial trial re-evaluations. 2027: Expected topline results for the elsunersen EMBRAVE3 registrational trial in early-seizure-onset SCN2A DEE.
0 · Reply
Trainguy1
Trainguy1 Aug. 7 at 5:05 PM
$PRAX Upcoming PDUFA Dates - December 27, 2026: Relutrigine for the treatment of SCN2A and SCN8A developmental and epileptic encephalopathies (DEEs). January 29, 2027: Ulixacaltamide for the treatment of essential tremor (ET) in adults.
0 · Reply
NoHandOutz
NoHandOutz Aug. 7 at 1:24 PM
$IOVA $SITM $PRAX ZENA drone manufacturer is getting a big squeeze this morning!!
1 · Reply