Market Cap 4.95B
Revenue (ttm) 0.00
Net Income (ttm) -255.86M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.15
Volume 1,927,867
Avg Vol 3,505,690
Day's Range N/A - N/A
Shares Out 142.38M
Stochastic %K 45%
Beta 0.50
Analysts Strong Sell
Price Target $49.09

Company Profile

Cogent Biosciences, Inc., a biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The c...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 945 5576
Address:
275 Wyman Street, 3rd Floor, Waltham, United States
ignoreo
ignoreo Jan. 6 at 5:27 PM
$COGT risk free 2x
1 · Reply
AStrokeOfLuck
AStrokeOfLuck Dec. 30 at 10:57 PM
1 · Reply
prismmarketview
prismmarketview Dec. 30 at 3:24 PM
Cogent Biosciences $COGT Submits New Drug Application for Bezuclastinib in NonAdvanced Systemic Mastocytosis https://prismmarketview.com/cogent-biosciences-submits-new-drug-application-for-bezuclastinib-in-nonadvanced-systemic-mastocytosis/
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Quantumup
Quantumup Dec. 30 at 3:08 PM
Raymond James reiterated $COGT Strong Buy/$60 BPMC - $SNY $NVS $OPHLY $CLDX GSK Here's what Raymond James had to say: Remain Strong Buy rated on COGT shares following this morning's expected announcement of their first NDA submission of bezuclastinib in Non-Advanced Systemic Mastocytosis (NonAdvSM). Recall, Cogent has guided to submitting this NDA by YE25 based on (1) positive SUMMIT data and (2) Breakthrough Therapy Designation (BTD) for bezu in patients with smoldering SM (SSM) and those previously treated with avapritinib. Moreover, Cogent plans to submit two more NDAs in gastrointestinal stromal tumors (GIST) and Advanced SM (ASM) in 1H26. We anticipate shares will continue to work in 2026 as management executes on these regulatory milestones and as enrollment in bezu's GIST expanded access program progresses. We currently model bezuclastinib launch in NonAdvSM in 4Q26 and revenues of $170.5M, $260.9M, $487.9M, and $678.6M for FY27-30, respectively.
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ciobanuaicea
ciobanuaicea Dec. 30 at 2:50 PM
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DonCorleone77
DonCorleone77 Dec. 30 at 1:11 PM
$COGT Cogent Biosciences submits NDA for bezuclastinib in NonAdvSM Cogent Biosciences submitted its New Drug Application to the U.S. Food and Drug Administration for bezuclastinib in NonAdvanced Systemic Mastocytosis. The submission is based on positive clinical data from the SUMMIT pivotal trial and follows the Breakthrough Therapy Designation for bezuclastinib in patients with SSM and patients with NonAdvSM who have received prior avapritinib. As reported first in July, and more recently at the ASH annual meeting, the SUMMIT trial of bezuclastinib in patients with NonAdvSM achieved statistical significance across all primary and key secondary endpoints. Bezuclastinib demonstrated clear clinical benefit across all symptom domains, including significant improvements across 11 individual patient reported symptoms as well as the most severe symptom at baseline. Reductions in objective measures of disease, including serum tryptase, correlated with improvements in symptom severity, representing the first time this relationship has been demonstrated in patients with NonAdvSM. Updated data from the SUMMIT trial through 48 weeks showcased a clear and continued deepening of symptomatic improvement over time, supporting the potential for sustained clinical benefit with longer duration of therapy. Across the SUMMIT trial, bezuclastinib de ...
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Midori_Hachi
Midori_Hachi Dec. 28 at 7:08 AM
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SapphireScribe
SapphireScribe Dec. 27 at 10:07 AM
$COGT The backdrop favors measured delivery over aggressive expansion promises. Operational cadence needs to tighten meaningfully. Predictability would attract a deeper institutional audience. Investors will likely insist on proof before expanding exposure.
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JarvisFlow
JarvisFlow Dec. 19 at 4:28 PM
JP Morgan has adjusted their stance on Cogent Biosciences ( $COGT ), setting the rating to Overweight with a target price of 65 → 67.
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RunnerSignals
RunnerSignals Dec. 12 at 9:45 PM
Morning Red Turns Afternoon Green $COGT $STIM $VERA $ANVS stumbled out the gate but soared into the close. market warriors showing how to flip the script in style
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ignoreo
ignoreo Jan. 6 at 5:27 PM
$COGT risk free 2x
1 · Reply
AStrokeOfLuck
AStrokeOfLuck Dec. 30 at 10:57 PM
1 · Reply
prismmarketview
prismmarketview Dec. 30 at 3:24 PM
Cogent Biosciences $COGT Submits New Drug Application for Bezuclastinib in NonAdvanced Systemic Mastocytosis https://prismmarketview.com/cogent-biosciences-submits-new-drug-application-for-bezuclastinib-in-nonadvanced-systemic-mastocytosis/
0 · Reply
Quantumup
Quantumup Dec. 30 at 3:08 PM
Raymond James reiterated $COGT Strong Buy/$60 BPMC - $SNY $NVS $OPHLY $CLDX GSK Here's what Raymond James had to say: Remain Strong Buy rated on COGT shares following this morning's expected announcement of their first NDA submission of bezuclastinib in Non-Advanced Systemic Mastocytosis (NonAdvSM). Recall, Cogent has guided to submitting this NDA by YE25 based on (1) positive SUMMIT data and (2) Breakthrough Therapy Designation (BTD) for bezu in patients with smoldering SM (SSM) and those previously treated with avapritinib. Moreover, Cogent plans to submit two more NDAs in gastrointestinal stromal tumors (GIST) and Advanced SM (ASM) in 1H26. We anticipate shares will continue to work in 2026 as management executes on these regulatory milestones and as enrollment in bezu's GIST expanded access program progresses. We currently model bezuclastinib launch in NonAdvSM in 4Q26 and revenues of $170.5M, $260.9M, $487.9M, and $678.6M for FY27-30, respectively.
0 · Reply
ciobanuaicea
ciobanuaicea Dec. 30 at 2:50 PM
0 · Reply
DonCorleone77
DonCorleone77 Dec. 30 at 1:11 PM
$COGT Cogent Biosciences submits NDA for bezuclastinib in NonAdvSM Cogent Biosciences submitted its New Drug Application to the U.S. Food and Drug Administration for bezuclastinib in NonAdvanced Systemic Mastocytosis. The submission is based on positive clinical data from the SUMMIT pivotal trial and follows the Breakthrough Therapy Designation for bezuclastinib in patients with SSM and patients with NonAdvSM who have received prior avapritinib. As reported first in July, and more recently at the ASH annual meeting, the SUMMIT trial of bezuclastinib in patients with NonAdvSM achieved statistical significance across all primary and key secondary endpoints. Bezuclastinib demonstrated clear clinical benefit across all symptom domains, including significant improvements across 11 individual patient reported symptoms as well as the most severe symptom at baseline. Reductions in objective measures of disease, including serum tryptase, correlated with improvements in symptom severity, representing the first time this relationship has been demonstrated in patients with NonAdvSM. Updated data from the SUMMIT trial through 48 weeks showcased a clear and continued deepening of symptomatic improvement over time, supporting the potential for sustained clinical benefit with longer duration of therapy. Across the SUMMIT trial, bezuclastinib de ...
0 · Reply
Midori_Hachi
Midori_Hachi Dec. 28 at 7:08 AM
0 · Reply
SapphireScribe
SapphireScribe Dec. 27 at 10:07 AM
$COGT The backdrop favors measured delivery over aggressive expansion promises. Operational cadence needs to tighten meaningfully. Predictability would attract a deeper institutional audience. Investors will likely insist on proof before expanding exposure.
0 · Reply
JarvisFlow
JarvisFlow Dec. 19 at 4:28 PM
JP Morgan has adjusted their stance on Cogent Biosciences ( $COGT ), setting the rating to Overweight with a target price of 65 → 67.
0 · Reply
RunnerSignals
RunnerSignals Dec. 12 at 9:45 PM
Morning Red Turns Afternoon Green $COGT $STIM $VERA $ANVS stumbled out the gate but soared into the close. market warriors showing how to flip the script in style
0 · Reply
BioBum
BioBum Dec. 11 at 11:39 PM
$VTGN $COGT had a Friday morning PR. Give it to us
1 · Reply
aristocks
aristocks Dec. 11 at 7:04 PM
$COGT lets go! moving higher! Added more and looking for really short term price target of 44$ As usual, will sell most of my position for a short (big) trade and keep around 100 shares to: 1. keep riding the rollercoster 2. keep an eye on the stock in case it gets buyout or Institutions interest! Not financial advice. Do your DD.
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matmasr
matmasr Dec. 9 at 5:55 PM
These are year to date Moon Shot Alerts from a scanner I created using TradeIdeas. The alert triggers in $10-$12 Range. Most of the stocks on this list have seen double and tripple growth from the alert like $NEGG $COGT and $REZI. Get your TradeIdeas Subscribption at Grab your copy at https://go.trade-ideas.com/SH15b and use code "matmasr" for 15% off.
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JarvisFlow
JarvisFlow Dec. 8 at 4:17 PM
Needham updates rating for Cogent Biosciences ( $COGT ) to Hold.
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DonCorleone77
DonCorleone77 Dec. 8 at 2:07 PM
$COGT $AVGO $CRWV $MRVL $TSLA PRE-MARKET MOVERS: Currently Higher: - Kymera Therapeutics (KYMR) up 35.9% after reporting clinical results from the BroADen Phase 1b atopic dermatitis clinical trial of KT-621 - Cogent Biosciences (COGT) up 12.6% after announcing results of APEX trial of bezuclastinib - Confluent (CFLT) up 29.4% after entering into a definitive agreement under which IBM (IBM) will acquire all of the issued and outstanding common shares of the company for $31 per share - Broadcom (AVGO) up 3.5% after The Information reported Microsoft (MSFT) is in talks to design custom chips with Broadcom, switching its business from Marvell (MRVL) Currently Lower: - Marvell (MRVL) down 7.1% after the report that Microsoft (MSFT) is in talks to design custom chips with Broadcom, switching its business from the company - CoreWeave (CRWV) down 4.1% after $2B convertible debt offering - Agios Pharmaceuticals (AGIO) down 1.2% after announcing that the FDA has not yet issued a regulatory decision on the supplemental new drug application for mitapivat for the treatment of adult patients with non-transfusion-dependent and transfusion-dependent alpha- or beta-thalassemia and that the sNDA remains under active review - Tesla (TSLA) down 1.4% after Morgan Stanley downgraded the stock to Equal Weight from Overweight with a price target of $425, up from $410, as a new analyst took over coverage - ITT (ITT) down 1.8% after 7M share common stock offering
1 · Reply
Quantumup
Quantumup Dec. 8 at 1:51 PM
Raymond James reiterated $COGT Strong Buy/$60 BPMC - $SNY $PFE $GSK $OPHLY Raymond James said: Remain Strong Buy rated on COGT shares after full SUMMIT data this weekend at ASH solidified bezuclastinib's efficacy advantage over competitor Ayvakit in non-advanced systemic mastocytosis (NonAdvSM). While SUMMIT was top lined last July, we got additional details around reduction of serum tryptase, bone marrow mast cell burden and circulating KIT p.D816V VAF that we think will contribute to the strong symptom score reduction advantage we've known since July. Coupling this with three-year data on Ayvakit that shows a modest improvement in total symptom score over time, we continue to believe bezuclastinib will compete for treatment naïve patients right out of the gate starting next year after approval and launch in NonAdvM. We continue to model bezuclastinib revenue in NonAdvSM of $170.5M, $260.9M, $487.9M, and $678.6M for FY27-FY30, respectively.
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OpenOutcrier
OpenOutcrier Dec. 8 at 1:40 PM
$COGT (+8.6% pre) Cogent Biosciences reports positive APEX trial results for bezuclastinib - SI https://ooc.bz/l/86607
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eddymaldives
eddymaldives Dec. 8 at 1:09 PM
$COGT LFG ! Give me 50
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HahaYouSUCK
HahaYouSUCK Dec. 8 at 12:46 PM
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WallStreetBuyDip
WallStreetBuyDip Dec. 7 at 1:29 AM
people asking about $COGT just watch H% get low like shown here
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justiceforb_85
justiceforb_85 Dec. 7 at 1:19 AM
$COGT outstanding data for bezuclastinib. Hope the market reacts positively to this news.
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ms0632
ms0632 Dec. 7 at 12:24 AM
$COGT are all those Dec $50 calls that were bought up last week going to pay on Monday based on the supplemental positive results?
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