Market Cap 2.79B
Revenue (ttm) 0.00
Net Income (ttm) -234.33M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 562,300
Avg Vol 844,714
Day's Range N/A - N/A
Shares Out 77.11M
Stochastic %K 1%
Beta 1.17
Analysts Strong Sell
Price Target $54.82

Company Profile

Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders in Canada. Its product candidates include Azetukalner, a selective Kv7 potassium channel opener in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major d...

Industry: Biotechnology
Sector: Healthcare
Phone: 604 484 3300
Fax: 604 484 3450
Address:
200-3650 Gilmore Way, Burnaby, Canada
Quantumup
Quantumup Sep. 3 at 7:09 PM
Wells Fargo assumed coverage of $XENE at an Overweight rating and a $48 price target. $JAZZ $BHVN $NBIX $PRAX RAPP SUPN Wells Fargo said: We are assuming coverage of $XENE at Overweight, as we think azetukalner is likely to succeed in X-TOLE2 given strong Ph2 data. We like that the 10mg dose worked in Ph2, implying some room for efficacy pullback (or placebo out-performance) in Ph3. $XENE expects the readout of its Ph3 X-TOLE2 study involving lead asset, azetukalner, in Focal Onset Seizures (FOS) in early 2026. We think consensus leans positive, and that many resonate with the strength of the Ph2. However, discontinuations were notable in Ph2, and we also think expectations were softened somewhat by the longer than expected Ph3 enrollment timeline.
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Christyatmond
Christyatmond Sep. 3 at 4:59 PM
$XENE bought a starter position
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JarvisFlow
JarvisFlow Sep. 3 at 1:00 PM
Wells Fargo updates rating for Xenon Pharmaceuticals ( $XENE ) to Overweight, target set at 48.
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JarvisFlow
JarvisFlow Sep. 2 at 1:30 PM
RBC Capital has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 55.
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Rx2
Rx2 Aug. 17 at 8:46 PM
$XENE melt up into data? Seems like $55+ inevitable here by data early q1
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perchedcats
perchedcats Aug. 13 at 2:39 PM
$XENE finally this stock wakes up. next 6-9 months are huge good time to be in. glad i added in low 30s a few weeks ago.
0 · Reply
victorgn
victorgn Aug. 12 at 6:51 PM
$XENE here the run starts...
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victorgn
victorgn Aug. 12 at 6:20 PM
$XENE 36.5 $ for starts
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ZacksResearch
ZacksResearch Aug. 12 at 2:59 PM
$XENE Q2 loss wider than expected — what's next for the stock? Reported a loss of $1.07 per share, missing the Zacks Consensus Estimate of a $1.03 loss. R&D expenses soared 51% YoY, driven by ongoing late-stage studies in epilepsy and MDD. Cash reserves at $624.8M, expected to fund operations, including completion of azetukalner phase III epilepsy studies and supporting late-stage clinical development of azetukalner in MDD and BPD, into 2027. See the full breakdown here 👉 https://www.zacks.com/stock/news/2702430/xenon-q2-loss-wider-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2702430-body-7382&ADID=SYND_STOCKTWITS_TWEET_2_2702430_BODY_7382
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JarvisFlow
JarvisFlow Aug. 12 at 2:15 PM
RBC Capital has updated their rating for Xenon Pharmaceuticals ( $XENE ) to Outperform with a price target of 55.
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Latest News on XENE
Xenon to Report Q2 2025 Financial Results on August 11, 2025

Aug 4, 2025, 8:01 AM EDT - 5 weeks ago

Xenon to Report Q2 2025 Financial Results on August 11, 2025


Xenon Joins the Russell 3000® and Russell 2000® Indexes

Jun 27, 2025, 4:01 PM EDT - 2 months ago

Xenon Joins the Russell 3000® and Russell 2000® Indexes


Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript

May 12, 2025, 10:06 PM EDT - 4 months ago

Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript


Xenon to Report Q1 2025 Financial Results on May 12, 2025

May 5, 2025, 4:01 PM EDT - 4 months ago

Xenon to Report Q1 2025 Financial Results on May 12, 2025


Xenon- A Later Stage Story

Apr 18, 2025, 3:36 AM EDT - 5 months ago

Xenon- A Later Stage Story


Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data

Apr 4, 2025, 4:23 PM EDT - 5 months ago

Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data


Xenon to Present at Stifel 2025 Virtual CNS Forum

Mar 12, 2025, 4:01 PM EDT - 6 months ago

Xenon to Present at Stifel 2025 Virtual CNS Forum


Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript

Feb 27, 2025, 11:53 PM EST - 7 months ago

Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript


Xenon Outlines Key Corporate Milestone Opportunities for 2025

Jan 13, 2025, 8:30 AM EST - 8 months ago

Xenon Outlines Key Corporate Milestone Opportunities for 2025


Xenon to Showcase New Long-Term Azetukalner Data at AES 2024

Nov 25, 2024, 8:30 AM EST - 10 months ago

Xenon to Showcase New Long-Term Azetukalner Data at AES 2024


Xenon to Present at Upcoming Investor Conferences

Nov 13, 2024, 4:01 PM EST - 10 months ago

Xenon to Present at Upcoming Investor Conferences


Xenon Pharmaceuticals Inc. (XENE) Q3 2024 Earnings Call Transcript

Nov 12, 2024, 10:49 PM EST - 10 months ago

Xenon Pharmaceuticals Inc. (XENE) Q3 2024 Earnings Call Transcript


Xenon Reports Q3 2024 Financial Results and Business Update

Nov 12, 2024, 4:01 PM EST - 10 months ago

Xenon Reports Q3 2024 Financial Results and Business Update


Xenon to Report Q3 2024 Financial Results on November 12, 2024

Nov 5, 2024, 4:01 PM EST - 11 months ago

Xenon to Report Q3 2024 Financial Results on November 12, 2024


Xenon Reports Q2 2024 Financial Results and Business Update

Aug 8, 2024, 4:01 PM EDT - 1 year ago

Xenon Reports Q2 2024 Financial Results and Business Update


Xenon to Report Q2 2024 Financial Results on August 8, 2024

Aug 1, 2024, 4:01 PM EDT - 1 year ago

Xenon to Report Q2 2024 Financial Results on August 8, 2024


Quantumup
Quantumup Sep. 3 at 7:09 PM
Wells Fargo assumed coverage of $XENE at an Overweight rating and a $48 price target. $JAZZ $BHVN $NBIX $PRAX RAPP SUPN Wells Fargo said: We are assuming coverage of $XENE at Overweight, as we think azetukalner is likely to succeed in X-TOLE2 given strong Ph2 data. We like that the 10mg dose worked in Ph2, implying some room for efficacy pullback (or placebo out-performance) in Ph3. $XENE expects the readout of its Ph3 X-TOLE2 study involving lead asset, azetukalner, in Focal Onset Seizures (FOS) in early 2026. We think consensus leans positive, and that many resonate with the strength of the Ph2. However, discontinuations were notable in Ph2, and we also think expectations were softened somewhat by the longer than expected Ph3 enrollment timeline.
0 · Reply
Christyatmond
Christyatmond Sep. 3 at 4:59 PM
$XENE bought a starter position
0 · Reply
JarvisFlow
JarvisFlow Sep. 3 at 1:00 PM
Wells Fargo updates rating for Xenon Pharmaceuticals ( $XENE ) to Overweight, target set at 48.
0 · Reply
JarvisFlow
JarvisFlow Sep. 2 at 1:30 PM
RBC Capital has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 55.
0 · Reply
Rx2
Rx2 Aug. 17 at 8:46 PM
$XENE melt up into data? Seems like $55+ inevitable here by data early q1
0 · Reply
perchedcats
perchedcats Aug. 13 at 2:39 PM
$XENE finally this stock wakes up. next 6-9 months are huge good time to be in. glad i added in low 30s a few weeks ago.
0 · Reply
victorgn
victorgn Aug. 12 at 6:51 PM
$XENE here the run starts...
0 · Reply
victorgn
victorgn Aug. 12 at 6:20 PM
$XENE 36.5 $ for starts
0 · Reply
ZacksResearch
ZacksResearch Aug. 12 at 2:59 PM
$XENE Q2 loss wider than expected — what's next for the stock? Reported a loss of $1.07 per share, missing the Zacks Consensus Estimate of a $1.03 loss. R&D expenses soared 51% YoY, driven by ongoing late-stage studies in epilepsy and MDD. Cash reserves at $624.8M, expected to fund operations, including completion of azetukalner phase III epilepsy studies and supporting late-stage clinical development of azetukalner in MDD and BPD, into 2027. See the full breakdown here 👉 https://www.zacks.com/stock/news/2702430/xenon-q2-loss-wider-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2702430-body-7382&ADID=SYND_STOCKTWITS_TWEET_2_2702430_BODY_7382
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JarvisFlow
JarvisFlow Aug. 12 at 2:15 PM
RBC Capital has updated their rating for Xenon Pharmaceuticals ( $XENE ) to Outperform with a price target of 55.
0 · Reply
ZacksResearch
ZacksResearch Aug. 12 at 1:59 PM
$XENE loss widens — but pipeline bets are getting bigger Q2 came in weaker than expected as the company pours resources into late-stage trials for epilepsy, depression, and bipolar disorder with azetukalner. Full breakdown of the pipeline push here 👉 https://www.zacks.com/stock/news/2702430/xenon-q2-loss-wider-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2702430-teaser-7378&ADID=SYND_STOCKTWITS_TWEET_2_2702430_TEASER_7378
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JarvisFlow
JarvisFlow Aug. 12 at 1:27 PM
Wedbush has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 42 → 43.
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topstockalerts
topstockalerts Aug. 12 at 12:11 PM
$XENE Looking good! -👀...👀-
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Nerevarine
Nerevarine Aug. 12 at 5:53 AM
$XENE Really good pick up and a positive surprise this Q2. Primed and loaded
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d_risk
d_risk Aug. 12 at 1:21 AM
$XENE - Xenon Pharmaceuticals Inc. Common Shares - 10Q - Updated Risk Factors XENE’s 10-Q risk factors now spotlight deepening losses, uncertain funding, and heavy reliance on few R&D programs, with new risks from currency swings, third-party dependencies, and expanded IP and cybersecurity threats; competition and key personnel risks were dropped, while compliance, international, and commercialization challenges are more detailed than ever. #Pharmaceuticals #IPSecurity #CurrencyRisk #FundingUncertainty #R&DRisk 🟢 Added 🟠 Removed https://d-risk.ai/XENE/10-Q/2025-08-11
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Quantumup
Quantumup Aug. 11 at 12:51 PM
Piper Sandler reitd $PRAX OW/$270. Following positive Ph2 RADIANT FOS data, we hosted $PRAX for a fireside chat and learned new details reaffirming vormatrigine's competitive and potentially transformational product profile. Specifically, mgmt highlighted vormatrigine showed a consistent PK profile in refractory FOS (vs HVs) with a linear response across AUC and Cmax effectively derisking 40 mg may drive deeper efficacy. Additionally, mgmt specified most discontinuations occurred during weeks 1-3 of RADIANT where blinded Ph2/3 POWER1 data is showing substantially fewer discontinuations thus far. In that vein, mgmt detailed POWER1 is "at-least" 80% powered to show a placebo-adjusted 30% reduction in median seizure frequency where competitor data suggests consistent response across open-label and randomized placebo-controlled trials. Hence, we came away from the fireside chat even more confident in vormatrigine's value proposition with full RADIANT data and POWER1 completion 4Q25. $XENE $BHVN
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ChessGM
ChessGM Aug. 3 at 1:18 AM
$XENE "Heads up alert! Upcoming earnings on Friday, 8/8/2025 for $XENE Bullish (7.8) --- Financial Analysis of Xenon Pharmaceuticals (NASDAQ: XENE): Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical entity, continues to draw investor attention with its advancements in the epilepsy treatment domain, notably its promising Phase III trials. RBC Capital's recent price target increase to $57, citing optimism around Xenon's pipeline, underscores this positive outlook. Despite being currently unprofitable—a common trait among biotechs in the R&D phase—Xenon is strategically leveraging its cash reserves to fuel growth and innovation. The company's inclusion in both the Russell 2000® and Russell 3000® Indexes marks a significant milestone, enhancing its visibility and investor base. From a valuation perspective, traditional metrics such as P/E ratio are not applicable due to its current unprofitable status. However, the company's projected revenue growth, driven by potential market entry of its epilepsy drug, remains a focal point. Comparatively, Xenon's growth prospects and innovative pipeline position it favorably against industry peers. Analysts are optimistic, given its strategic maneuvers, including key executive appointments aimed at bolstering its transition to a commercial-stage entity. Upcoming Earnings Report Outlook: Xenon Pharmaceuticals is poised for its upcoming earnings report, with market expectations centered on updates regarding its clinical pipeline progress, particularly the epilepsy drug's Phase III trials. Historically, the company has demonstrated robust scientific milestones, and current consensus estimates suggest continued revenue growth as the company transitions towards commercialization. While exact figures remain speculative, any positive developments could further elevate investor confidence and stock valuation. Sector Performance: The biotechnology sector, to which Xenon Pharmaceuticals belongs, has exhibited varied performance, with a general trend towards recovery following recent market volatility. Innovation-driven growth remains a common theme, with companies focusing on niche therapeutic areas showing particular resilience. Xenon's focus on neuroscience therapeutics places it in a competitive position within a sector increasingly characterized by strategic R&D investments and partnerships aimed at addressing unmet medical needs. - Funds were net sellers of $XENE during the previous reporting quarter. - Funds with large holdings in $XENE include: - Avoro Capital Advisors LLC, MV: $193MM. Fund Rank: 76% avorocapital.com - Adage Capital P, MV: $64MM. Fund Rank: 86% www.adagecapital.com - Westfield Capital Management Company LP, MV: $47MM. Fund Rank: 83% www.westfieldcapital.com - OrbiMed Advisors LLC, MV: $32MM. Fund Rank: 55% www.orbimed.com - First Light Asset Management LLC, MV: $21MM. Fund Rank: 55% www.firstlightam.com - Last 10 days performance: -3% - Last 30 days performance: -8% - Last 90 days performance: -20% Some of the latest news articles: - Title: Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) Publication Date: 8/1/2025 8:55:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-pharmaceuticals-reports-inducement-grants-205500097.html?.tsrc=rss - Title: We're Hopeful That Xenon Pharmaceuticals (NASDAQ:XENE) Will Use Its Cash Wisely Publication Date: 7/14/2025 11:23:03 AM, Source: yahoo URL: https://finance.yahoo.com/news/were-hopeful-xenon-pharmaceuticals-nasdaq-112303203.html?.tsrc=rss - Title: RBC Raises Xenon Price Target, Cites Phase III Optimism for Epilepsy Drug Publication Date: 7/2/2025 7:20:51 AM, Source: yahoo URL: https://finance.yahoo.com/news/rbc-raises-xenon-price-target-072051603.html?.tsrc=rss - Title: Xenon Joins the Russell 3000® and Russell 2000® Indexes Publication Date: 6/27/2025 8:01:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-joins-russell-3000-russell-200100893.html?.tsrc=rss Follow us on stocktwits.com. Not a financial advice. Not a trading signal."
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NVDAMillionaire
NVDAMillionaire Jul. 29 at 6:50 PM
$XENE Great piece that accurately captures XENE's current position. So if you want to refresh your understanding of XENE or learn about XENE for the first time, this is essential reading. https://beyondspx.com/article/xenon-pharmaceuticals-unlocking-ion-channel-potential-at-a-pivotal-juncture-nasdaq-xene
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Dylanjaret
Dylanjaret Jul. 19 at 4:50 AM
$XENE reclaiming moving averages. Bullish setup forming.
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Quantumup
Quantumup Jul. 18 at 12:46 PM
H.C. Wainwright reitd $PRAX Buy-$105 after Praxis announced that FDA had granted Breakthrough Therapy Designation (BTD) for relutrigine, for the treatment of pediatric patients with SCN2A and SCN8A DEEs. $RAPP $XENE $BHVN $DRUG NBIX ( LBPH - HLBBF HLUBF) H.C. Wainwright said in its note: "While investor attention has largely been on the upcoming readout of vormatrigine's RADIANT study in focal onset seizures, there has been increasing appreciation that relutrigine is deserving of attention. There's a case to be made that relutrigine's commercial potential in DEEs may even exceed vormatrigine's potential in FOS—we make that statement despite being "bulls" on the vormatrigine story. We believe the efficacy that relutrigine demonstrated in the EMBOLD study was potentially paradigm-shifting in its ability to offer seizure freedom to patients. H.C. Wainwright went on to say:
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Quantumup
Quantumup Jul. 16 at 10:02 AM
Citizens reiterated $RAPP Market Outperform-$28 after a KOL call reinforced its confidence in the pot'l for positive RAP-219 Phase 2 results in focal epilepsy. $PRAX $XENE $BHVN $NBIX TAK UCBJY Citizens said in its note: "We recently hosted Dr. Vikram Rao, a neurologist from UCSF and epilepsy KOL, for a discussion on the upcoming Phase 2 proof-of-concept results for RAP-219 in focal epilepsy. Dr. Rao is optimistic about the potential for RAP-219 in focal epilepsy due to its validated yet differentiated mechanism of action, compelling preclinical results, and innovative Phase 2 trial design. RAPP remains one of our two high-conviction calls into the Phase 2 results in September."
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Quantumup
Quantumup Jul. 10 at 3:01 PM
Piper Sandler reiterated $PRAX Overweight-$270 and Provided its Takeaways From Their Well-Attended NYC Investor Dinner, Ahead of Ph2 RADIANT $NBIX $BHVN $XENE AQST $BIIB DNLI JAZZ UCBJF Piper Sandler said in it research report:
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