Market Cap 3.09B
Revenue (ttm) 0.00
Net Income (ttm) -234.33M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,060,500
Avg Vol 776,876
Day's Range N/A - N/A
Shares Out 77.28M
Stochastic %K 89%
Beta 1.10
Analysts Strong Sell
Price Target $54.92

Company Profile

Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders in Canada. Its product candidates include Azetukalner, a selective Kv7 potassium channel opener in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major d...

Industry: Biotechnology
Sector: Healthcare
Phone: 604 484 3300
Fax: 604 484 3450
Address:
200-3650 Gilmore Way, Burnaby, Canada
JarvisFlow
JarvisFlow Nov. 4 at 4:47 PM
RBC Capital has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 55 → 58.
1 · Reply
JarvisFlow
JarvisFlow Nov. 4 at 4:04 PM
Wells Fargo has updated their rating for Xenon Pharmaceuticals ( $XENE ) to Overweight with a price target of 44.
1 · Reply
ZacksResearch
ZacksResearch Nov. 4 at 3:31 PM
$XENE Q3: Narrower Loss, Still No Revenues — What's Next? Xenon Pharmaceuticals reported a Q3 loss of $1.15 per share, slightly narrower than the Zacks Consensus Estimate of a $1.16 loss. Despite no revenue recognition from collaboration, increased R&D and administrative expenses reflect ongoing investments in late-stage epilepsy and depression studies. See what's driving XENE's future prospects here 👉 https://www.zacks.com/stock/news/2784674/xenon-q3-loss-narrower-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2784674-body-19293&ADID=SYND_STOCKTWITS_TWEET_2_2784674_BODY_19293
0 · Reply
ZacksResearch
ZacksResearch Nov. 4 at 2:31 PM
$XENE loss narrows — but the real story is its advancing pipeline. The biotech beat loss expectations and is pushing multiple late-stage studies of azetukalner in epilepsy and mood disorders — a major focus for growth ahead. Full pipeline update here 👉 https://www.zacks.com/stock/news/2784674/xenon-q3-loss-narrower-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2784674-teaser-19272&ADID=SYND_STOCKTWITS_TWEET_2_2784674_TEASER_19272
0 · Reply
JarvisFlow
JarvisFlow Nov. 4 at 9:18 AM
Needham updates rating for Xenon Pharmaceuticals ( $XENE ) to Buy, target set at 55.
0 · Reply
Sawnchey
Sawnchey Nov. 3 at 9:57 PM
$XENE I always enjoy an earnings overreaction. All studies still on track with Phase-3 topline data due in Early 2026, and multiple additional shots on goal. With the high rate of X-TOLE 2 patients rolling over to OLE, I am feeling confident in a good result, which could lead into a stacked year of milestones: P3 data for FOS, if successful then NDA filing for FOS, enrolment updates in the PGTCS indication & psychiatric studies, and P1 data from the early stage pipeline and initiations of P2 studies.
1 · Reply
ChessGM
ChessGM Nov. 2 at 12:58 AM
$XENE "Heads up alert! Only two days until Upcoming earnings on Monday, 11/3/2025 for $XENE Neutral (5.5) Xenon Pharmaceuticals Inc. (XENE) has demonstrated a mix of positive and cautious developments in its recent trajectory. The company is set to report its Q3 2025 financial results on November 3, 2025, which is anticipated to provide crucial insights into its operational performance and strategic direction. Historically, Xenon has experienced fluctuations in its earnings, with a focus on its neuroscience portfolio that includes promising drug candidates. The appointment of Tucker Kelly as CFO signals a potential shift towards a more strategic financial management approach, which could enhance investor confidence. Recent share price momentum, with a 9% increase over the last month and a 22% rise in the past three months, indicates growing investor interest, although the one-year total return remains slightly negative. Key financial metrics, such as the P/E ratio and EPS growth, are yet to be disclosed in the upcoming earnings report but will be critical for assessing the company's valuation relative to its industry peers. The biopharmaceutical sector has been characterized by heightened volatility, but Xenon's focused approach on drug discovery and commercialization positions it uniquely within this landscape. In terms of upcoming earnings reports, there is anticipation surrounding Xenon's Q3 2025 results. Analysts are likely to focus on revenue forecasts and any updates regarding clinical trials or drug approvals, which could significantly impact the stock’s performance. Historical performance has shown variability, but the recent strategic appointments and ongoing clinical developments may provide a more favorable outlook. Analyst consensus estimates are expected to reflect cautious optimism, particularly in light of the recent share price recovery. The biopharmaceutical sector as a whole has been performing variably, influenced by regulatory approvals and market dynamics, but companies like Xenon that are focusing on innovative therapeutic solutions are likely to attract continued interest from investors. - Funds were net buyers of $XENE during the previous reporting quarter. - Funds with large holdings in $XENE include: - Avoro Capital Advisors LLC, MV: $169MM. Fund Rank: 88% avorocapital.com - Driehaus Capital, MV: $136MM. Fund Rank: 58% - Holocene Advisors LP, MV: $57MM. New position. Fund Rank: 84% www.holoceneadvisors.com - Adage Capital P, MV: $40MM. Fund Rank: 89% www.adagecapital.com - Westfield Capital Management Company LP, MV: $36MM. Fund Rank: 84% www.westfieldcapital.com - Last 10 days performance: -1% - Last 30 days performance: 7% - Last 90 days performance: 37% Some of the latest news articles: - Title: Xenon to Report Q3 2025 Financial Results on November 3, 2025 Publication Date: 10/27/2025 12:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-report-q3-2025-financial-123000857.html?.tsrc=rss - Title: Xenon Announces Appointment of Tucker Kelly as Chief Financial Officer Publication Date: 10/16/2025 12:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-announces-appointment-tucker-kelly-123000444.html?.tsrc=rss - Title: Xenon Pharmaceuticals (XENE): Exploring Valuation After Recent Share Price Momentum Publication Date: 10/12/2025 10:09:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-pharmaceuticals-xene-exploring-valuation-100900879.html?.tsrc=rss - Title: Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) Publication Date: 10/7/2025 8:01:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-pharmaceuticals-reports-inducement-grants-200100194.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
1 · Reply
JFais
JFais Nov. 1 at 8:52 PM
$BHVN- appreciate the added color @JoseRestonVA (why you're staying long after my exit) Agree, think SCA merits a green light given nothing else approved and RWE data on slowing disease progression + reduction in fall risk (FDA just so unpredictable...) I also like the kv7 space ( $XENE a prior winner) as well as their degrader platform (the latter has a LOT of potential) However, needs $$ to fund development and part of my selection criteria is wanting strong balance sheets + reasonable burn rate (learned that from TDMInvest) Why I chose to take profits despite the very high upside nature of the setup
1 · Reply
JarvisFlow
JarvisFlow Oct. 7 at 11:46 AM
Chardan Capital updates rating for Xenon Pharmaceuticals ( $XENE ) to Buy, target set at 55.
0 · Reply
nikitatrades
nikitatrades Oct. 7 at 11:21 AM
$XENE is advancing two novel, non-opioid pain drugs, XEN1120 (Kv7 opener) & XEN1701 (Nav1.7 inhibitor), both now in Phase 1 trials. The goal: effective pain relief without the risks of addiction or poor tolerability seen with current options. 🎯 Key differentiator for $XENE's Nav1.7 program: human genetics show only ~80% channel inhibition is needed for efficacy, making it a more achievable target. Their lead compound, XEN1701, is CNS-penetrant with high selectivity, a profile never before tested in clinic. $XENE plans to initiate Phase 2 proof-of-concept studies for both pain programs in 2026. Targets have broad potential across acute & chronic pain conditions. A deep pipeline of additional Kv7/Nav1.7 compounds is in development. 📈
0 · Reply
Latest News on XENE
Xenon to Present at Upcoming Investor Conferences

Nov 6, 2025, 8:30 AM EST - 8 days ago

Xenon to Present at Upcoming Investor Conferences


Xenon to Report Q3 2025 Financial Results on November 3, 2025

Oct 27, 2025, 8:30 AM EDT - 18 days ago

Xenon to Report Q3 2025 Financial Results on November 3, 2025


Xenon Pharmaceuticals Inc. - Special Call

Oct 6, 2025, 3:45 PM EDT - 5 weeks ago

Xenon Pharmaceuticals Inc. - Special Call


Xenon Pharmaceuticals Inc. (XENE) Q2 2025 Earnings Call Transcript

Aug 11, 2025, 11:44 PM EDT - 3 months ago

Xenon Pharmaceuticals Inc. (XENE) Q2 2025 Earnings Call Transcript


Xenon to Report Q2 2025 Financial Results on August 11, 2025

Aug 4, 2025, 8:01 AM EDT - 3 months ago

Xenon to Report Q2 2025 Financial Results on August 11, 2025


Xenon Joins the Russell 3000® and Russell 2000® Indexes

Jun 27, 2025, 4:01 PM EDT - 5 months ago

Xenon Joins the Russell 3000® and Russell 2000® Indexes


Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript

May 12, 2025, 10:06 PM EDT - 6 months ago

Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript


Xenon to Report Q1 2025 Financial Results on May 12, 2025

May 5, 2025, 4:01 PM EDT - 6 months ago

Xenon to Report Q1 2025 Financial Results on May 12, 2025


Xenon- A Later Stage Story

Apr 18, 2025, 3:36 AM EDT - 7 months ago

Xenon- A Later Stage Story


Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data

Apr 4, 2025, 4:23 PM EDT - 8 months ago

Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data


Xenon to Present at Stifel 2025 Virtual CNS Forum

Mar 12, 2025, 4:01 PM EDT - 8 months ago

Xenon to Present at Stifel 2025 Virtual CNS Forum


Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript

Feb 27, 2025, 11:53 PM EST - 9 months ago

Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript


Xenon Outlines Key Corporate Milestone Opportunities for 2025

Jan 13, 2025, 8:30 AM EST - 10 months ago

Xenon Outlines Key Corporate Milestone Opportunities for 2025


Xenon to Showcase New Long-Term Azetukalner Data at AES 2024

Nov 25, 2024, 8:30 AM EST - 1 year ago

Xenon to Showcase New Long-Term Azetukalner Data at AES 2024


Xenon Reports Q3 2024 Financial Results and Business Update

Nov 12, 2024, 4:01 PM EST - 1 year ago

Xenon Reports Q3 2024 Financial Results and Business Update


Xenon Reports Q2 2024 Financial Results and Business Update

Aug 8, 2024, 4:01 PM EDT - 1 year ago

Xenon Reports Q2 2024 Financial Results and Business Update


Xenon to Report Q2 2024 Financial Results on August 8, 2024

Aug 1, 2024, 4:01 PM EDT - 1 year ago

Xenon to Report Q2 2024 Financial Results on August 8, 2024


JarvisFlow
JarvisFlow Nov. 4 at 4:47 PM
RBC Capital has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 55 → 58.
1 · Reply
JarvisFlow
JarvisFlow Nov. 4 at 4:04 PM
Wells Fargo has updated their rating for Xenon Pharmaceuticals ( $XENE ) to Overweight with a price target of 44.
1 · Reply
ZacksResearch
ZacksResearch Nov. 4 at 3:31 PM
$XENE Q3: Narrower Loss, Still No Revenues — What's Next? Xenon Pharmaceuticals reported a Q3 loss of $1.15 per share, slightly narrower than the Zacks Consensus Estimate of a $1.16 loss. Despite no revenue recognition from collaboration, increased R&D and administrative expenses reflect ongoing investments in late-stage epilepsy and depression studies. See what's driving XENE's future prospects here 👉 https://www.zacks.com/stock/news/2784674/xenon-q3-loss-narrower-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2784674-body-19293&ADID=SYND_STOCKTWITS_TWEET_2_2784674_BODY_19293
0 · Reply
ZacksResearch
ZacksResearch Nov. 4 at 2:31 PM
$XENE loss narrows — but the real story is its advancing pipeline. The biotech beat loss expectations and is pushing multiple late-stage studies of azetukalner in epilepsy and mood disorders — a major focus for growth ahead. Full pipeline update here 👉 https://www.zacks.com/stock/news/2784674/xenon-q3-loss-narrower-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2784674-teaser-19272&ADID=SYND_STOCKTWITS_TWEET_2_2784674_TEASER_19272
0 · Reply
JarvisFlow
JarvisFlow Nov. 4 at 9:18 AM
Needham updates rating for Xenon Pharmaceuticals ( $XENE ) to Buy, target set at 55.
0 · Reply
Sawnchey
Sawnchey Nov. 3 at 9:57 PM
$XENE I always enjoy an earnings overreaction. All studies still on track with Phase-3 topline data due in Early 2026, and multiple additional shots on goal. With the high rate of X-TOLE 2 patients rolling over to OLE, I am feeling confident in a good result, which could lead into a stacked year of milestones: P3 data for FOS, if successful then NDA filing for FOS, enrolment updates in the PGTCS indication & psychiatric studies, and P1 data from the early stage pipeline and initiations of P2 studies.
1 · Reply
ChessGM
ChessGM Nov. 2 at 12:58 AM
$XENE "Heads up alert! Only two days until Upcoming earnings on Monday, 11/3/2025 for $XENE Neutral (5.5) Xenon Pharmaceuticals Inc. (XENE) has demonstrated a mix of positive and cautious developments in its recent trajectory. The company is set to report its Q3 2025 financial results on November 3, 2025, which is anticipated to provide crucial insights into its operational performance and strategic direction. Historically, Xenon has experienced fluctuations in its earnings, with a focus on its neuroscience portfolio that includes promising drug candidates. The appointment of Tucker Kelly as CFO signals a potential shift towards a more strategic financial management approach, which could enhance investor confidence. Recent share price momentum, with a 9% increase over the last month and a 22% rise in the past three months, indicates growing investor interest, although the one-year total return remains slightly negative. Key financial metrics, such as the P/E ratio and EPS growth, are yet to be disclosed in the upcoming earnings report but will be critical for assessing the company's valuation relative to its industry peers. The biopharmaceutical sector has been characterized by heightened volatility, but Xenon's focused approach on drug discovery and commercialization positions it uniquely within this landscape. In terms of upcoming earnings reports, there is anticipation surrounding Xenon's Q3 2025 results. Analysts are likely to focus on revenue forecasts and any updates regarding clinical trials or drug approvals, which could significantly impact the stock’s performance. Historical performance has shown variability, but the recent strategic appointments and ongoing clinical developments may provide a more favorable outlook. Analyst consensus estimates are expected to reflect cautious optimism, particularly in light of the recent share price recovery. The biopharmaceutical sector as a whole has been performing variably, influenced by regulatory approvals and market dynamics, but companies like Xenon that are focusing on innovative therapeutic solutions are likely to attract continued interest from investors. - Funds were net buyers of $XENE during the previous reporting quarter. - Funds with large holdings in $XENE include: - Avoro Capital Advisors LLC, MV: $169MM. Fund Rank: 88% avorocapital.com - Driehaus Capital, MV: $136MM. Fund Rank: 58% - Holocene Advisors LP, MV: $57MM. New position. Fund Rank: 84% www.holoceneadvisors.com - Adage Capital P, MV: $40MM. Fund Rank: 89% www.adagecapital.com - Westfield Capital Management Company LP, MV: $36MM. Fund Rank: 84% www.westfieldcapital.com - Last 10 days performance: -1% - Last 30 days performance: 7% - Last 90 days performance: 37% Some of the latest news articles: - Title: Xenon to Report Q3 2025 Financial Results on November 3, 2025 Publication Date: 10/27/2025 12:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-report-q3-2025-financial-123000857.html?.tsrc=rss - Title: Xenon Announces Appointment of Tucker Kelly as Chief Financial Officer Publication Date: 10/16/2025 12:30:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-announces-appointment-tucker-kelly-123000444.html?.tsrc=rss - Title: Xenon Pharmaceuticals (XENE): Exploring Valuation After Recent Share Price Momentum Publication Date: 10/12/2025 10:09:00 AM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-pharmaceuticals-xene-exploring-valuation-100900879.html?.tsrc=rss - Title: Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) Publication Date: 10/7/2025 8:01:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/xenon-pharmaceuticals-reports-inducement-grants-200100194.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
1 · Reply
JFais
JFais Nov. 1 at 8:52 PM
$BHVN- appreciate the added color @JoseRestonVA (why you're staying long after my exit) Agree, think SCA merits a green light given nothing else approved and RWE data on slowing disease progression + reduction in fall risk (FDA just so unpredictable...) I also like the kv7 space ( $XENE a prior winner) as well as their degrader platform (the latter has a LOT of potential) However, needs $$ to fund development and part of my selection criteria is wanting strong balance sheets + reasonable burn rate (learned that from TDMInvest) Why I chose to take profits despite the very high upside nature of the setup
1 · Reply
JarvisFlow
JarvisFlow Oct. 7 at 11:46 AM
Chardan Capital updates rating for Xenon Pharmaceuticals ( $XENE ) to Buy, target set at 55.
0 · Reply
nikitatrades
nikitatrades Oct. 7 at 11:21 AM
$XENE is advancing two novel, non-opioid pain drugs, XEN1120 (Kv7 opener) & XEN1701 (Nav1.7 inhibitor), both now in Phase 1 trials. The goal: effective pain relief without the risks of addiction or poor tolerability seen with current options. 🎯 Key differentiator for $XENE's Nav1.7 program: human genetics show only ~80% channel inhibition is needed for efficacy, making it a more achievable target. Their lead compound, XEN1701, is CNS-penetrant with high selectivity, a profile never before tested in clinic. $XENE plans to initiate Phase 2 proof-of-concept studies for both pain programs in 2026. Targets have broad potential across acute & chronic pain conditions. A deep pipeline of additional Kv7/Nav1.7 compounds is in development. 📈
0 · Reply
BeyondBeatingMyMeat
BeyondBeatingMyMeat Sep. 23 at 11:22 PM
$BHVN Took some profit from $MYO and $BMA +20% in a couple days to average down here. Average now 14.7 Multiple catalysts to double from here by EoY. Approval, depression data, and $XENE data. Biohaven's drug outperformed Xenon in early trials and Biohaven is worth half of Xenon right now
1 · Reply
Quantumup
Quantumup Sep. 16 at 3:39 PM
UBS lowered $BHVN's PT to $26 from $27, reiterated Buy and said, we see meaningful upside to $BHVN stock if troriluzole is approved (Slide 1). Our base case models a 40% PoS for troriluzole with an estimated PDUFA date in mid-Nov (BHVN has not disclosed a date); we model ~$840M riskadj peak sales (Slide 4). Beyond troriluzole, we see value in rest of the pipeline: BHV-7000 (Kv7) has higher chance of working in focal epilepsy (1H26), while, degraders can generate long-term value. Our $26 PT (prior $27) is derived by applying an unchanged 4.5x multiple to EV/'30E sales, supported by DCF framework. We update EU SCA market entry to reflect MAA delays. Our new risk. adj.'30E troriluzole sales are $406M (prior $441M). $IMVT $XENE $ARGX $JNJ
0 · Reply
Quantumup
Quantumup Sep. 3 at 7:09 PM
Wells Fargo assumed coverage of $XENE at an Overweight rating and a $48 price target. $JAZZ $BHVN $NBIX $PRAX RAPP SUPN Wells Fargo said: We are assuming coverage of $XENE at Overweight, as we think azetukalner is likely to succeed in X-TOLE2 given strong Ph2 data. We like that the 10mg dose worked in Ph2, implying some room for efficacy pullback (or placebo out-performance) in Ph3. $XENE expects the readout of its Ph3 X-TOLE2 study involving lead asset, azetukalner, in Focal Onset Seizures (FOS) in early 2026. We think consensus leans positive, and that many resonate with the strength of the Ph2. However, discontinuations were notable in Ph2, and we also think expectations were softened somewhat by the longer than expected Ph3 enrollment timeline.
0 · Reply
Christyatmond
Christyatmond Sep. 3 at 4:59 PM
$XENE bought a starter position
0 · Reply
JarvisFlow
JarvisFlow Sep. 3 at 1:00 PM
Wells Fargo updates rating for Xenon Pharmaceuticals ( $XENE ) to Overweight, target set at 48.
0 · Reply
JarvisFlow
JarvisFlow Sep. 2 at 1:30 PM
RBC Capital has adjusted their stance on Xenon Pharmaceuticals ( $XENE ), setting the rating to Outperform with a target price of 55.
0 · Reply
Rx2
Rx2 Aug. 17 at 8:46 PM
$XENE melt up into data? Seems like $55+ inevitable here by data early q1
0 · Reply
perchedcats
perchedcats Aug. 13 at 2:39 PM
$XENE finally this stock wakes up. next 6-9 months are huge good time to be in. glad i added in low 30s a few weeks ago.
0 · Reply
victorgn
victorgn Aug. 12 at 6:51 PM
$XENE here the run starts...
0 · Reply
victorgn
victorgn Aug. 12 at 6:20 PM
$XENE 36.5 $ for starts
0 · Reply
ZacksResearch
ZacksResearch Aug. 12 at 2:59 PM
$XENE Q2 loss wider than expected — what's next for the stock? Reported a loss of $1.07 per share, missing the Zacks Consensus Estimate of a $1.03 loss. R&D expenses soared 51% YoY, driven by ongoing late-stage studies in epilepsy and MDD. Cash reserves at $624.8M, expected to fund operations, including completion of azetukalner phase III epilepsy studies and supporting late-stage clinical development of azetukalner in MDD and BPD, into 2027. See the full breakdown here 👉 https://www.zacks.com/stock/news/2702430/xenon-q2-loss-wider-than-expected-pipeline-development-in-focus?cid=sm-stocktwits-2-2702430-body-7382&ADID=SYND_STOCKTWITS_TWEET_2_2702430_BODY_7382
0 · Reply
JarvisFlow
JarvisFlow Aug. 12 at 2:15 PM
RBC Capital has updated their rating for Xenon Pharmaceuticals ( $XENE ) to Outperform with a price target of 55.
0 · Reply