Market Cap 3.19B
Revenue (ttm) 0.00
Net Income (ttm) -234.33M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 851,941
Avg Vol 876,556
Day's Range N/A - N/A
Shares Out 77.28M
Stochastic %K 6%
Beta 0.97
Analysts Strong Sell
Price Target $55.42

Company Profile

Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders in Canada. Its product candidates include Azetukalner, a selective Kv7 potassium channel opener in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major d...

Industry: Biotechnology
Sector: Healthcare
Phone: 604 484 3300
Fax: 604 484 3450
Address:
200-3650 Gilmore Way, Burnaby, Canada
hornetsnest23
hornetsnest23 Jan. 12 at 9:35 PM
$XENE Anyone else listen to today's JPM presentation?
1 · Reply
elmono
elmono Jan. 5 at 9:11 PM
$XENE $KURA $CRVS $KYTX I want my BO…anyone of these will do
0 · Reply
Quantumup
Quantumup Jan. 5 at 1:41 PM
Cantor⬆️ $XENE's PT to $55 from $45 and reiterated at an Overweight rating. $PRAX $BHVN $RAPP $NBIX JAZZ Cantor said in its note: Our "house view" is that most of the incremental value from current levels comes from the rest of the pipeline and not from seizures, so we're generally agnostic wrt XTOLE-2 as a catalyst. We also note that azetukalner exclusivity, while long-dated, will be driven more by polymorph, dosing and method patents. As such it may take 7-8 years to get a clearer sense of when generics might enter. However, azetukalner for seizures provides at least a strong valuation framework support, giving us cheap or free calls on the P3 depression program and the earlier stage programs highlighted above. Given their potentially transformational natures, these are programs we're keen to follow and make XENE a name with a compelling risk/reward profile over the long term, in our view.
0 · Reply
JFais
JFais Dec. 31 at 2:26 PM
agree re the LT story a better drug catches up (generally speaking) re $BHVN vs $XENE in meantime, a first mover often does quite well. See $SNDX in menin good example- agree in the LT frontline winners likely pharma, but in meantime 2026 to 2028+ Revuforj sales accelerating (& some off label)
1 · Reply
BioTechHealthX
BioTechHealthX Dec. 31 at 2:11 PM
$XENE Xenon Pharmaceuticals Inc. (NASDAQ:XENE) is expanding its lead drug beyond epilepsy into major depressive disorder and bipolar depression, potentially unlocking a much larger market for its precision neuroscience platform. https://biotechhealthx.com/biotech-news/from-rare-epilepsy-to-mental-health-why-xenon-pharmaceuticals-xene-is-expanding-fast/
0 · Reply
JFais
JFais Dec. 31 at 1:21 PM
one hurdle for $BHVN in Kv7 is $XENE has many more years' worth of patient data (huge gap in the race) Kind of reminds me of $NUVL in ROS1 chasing $NUVB in frontline ROS1 NSCLC (hard to overcome the 1st mover advantage, needs several more years to put out something comparable)
1 · Reply
JFais
JFais Dec. 31 at 1:21 PM
$XENE - Brief revisit ahead of early 2026 phase 3 epilepsy data $BHVN https://seekingalpha.com/instablog/440063-jonathan-faison/6242632-across-the-biotech-universe-xene?source=tweet
0 · Reply
JFais
JFais Dec. 31 at 1:22 AM
$XENE (NP) Across The Biotech Universe: Xenon Pharmaceuticals (brief revisit ahead of early 2026 phase 3 epilepsy data) $BHVN https://seekingalpha.com/instablog/440063-jonathan-faison/6242632-across-the-biotech-universe-xene?source=tweet
0 · Reply
Quantumup
Quantumup Dec. 26 at 1:31 PM
Stifel reit $XENE Buy-$60/said—We're reiterating our Buy rating on XENE on the back of BHVN's Kv7 failing in MDD. $BHVN $PRAX $JAZZ NBIX $RAPP Stifel added: Bottom line: we continue to believe that there's limited evidence suggesting that BHVN's Kv7 compound (BHV-7000) will be as efficacious as XEN1101. To be fair, MDD itself is risky and not yet de-risked for the Kv7 class -- it's still possible that Kv7s (including BHV-7000) end up having more limited utility in neuropsych, even if the mechanism is de-risked in FOS/epilepsy. That said, for BHV-7000 specifically, we continue to believe that to date, there's limited evidence of meaningful pharmacodynamic effect in the CNS: (1) we view prior EEG data as uninterpretable -- at the very least, less relevant to efficacy on actual seizures, and (2) we also believe the very clean AE/safety data of BHV-7000 raises the question of whether the drug is behaving like a potent anti-epileptic in the brain; we are skeptical of the GABA-selectivity thesis.
0 · Reply
LilySanders
LilySanders Dec. 26 at 1:18 PM
$XENE biotech tape stabilizing after reset looking for quiet accumulation and base
0 · Reply
Latest News on XENE
Xenon to Present at Upcoming Investor Conferences

Nov 6, 2025, 8:30 AM EST - 2 months ago

Xenon to Present at Upcoming Investor Conferences


Xenon to Report Q3 2025 Financial Results on November 3, 2025

Oct 27, 2025, 8:30 AM EDT - 2 months ago

Xenon to Report Q3 2025 Financial Results on November 3, 2025


Xenon Pharmaceuticals Inc. - Special Call

Oct 6, 2025, 3:45 PM EDT - 3 months ago

Xenon Pharmaceuticals Inc. - Special Call


Xenon Pharmaceuticals Inc. (XENE) Q2 2025 Earnings Call Transcript

Aug 11, 2025, 11:44 PM EDT - 5 months ago

Xenon Pharmaceuticals Inc. (XENE) Q2 2025 Earnings Call Transcript


Xenon to Report Q2 2025 Financial Results on August 11, 2025

Aug 4, 2025, 8:01 AM EDT - 5 months ago

Xenon to Report Q2 2025 Financial Results on August 11, 2025


Xenon Joins the Russell 3000® and Russell 2000® Indexes

Jun 27, 2025, 4:01 PM EDT - 7 months ago

Xenon Joins the Russell 3000® and Russell 2000® Indexes


Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript

May 12, 2025, 10:06 PM EDT - 8 months ago

Xenon Pharmaceuticals Inc. (XENE) Q1 2025 Earnings Call Transcript


Xenon to Report Q1 2025 Financial Results on May 12, 2025

May 5, 2025, 4:01 PM EDT - 9 months ago

Xenon to Report Q1 2025 Financial Results on May 12, 2025


Xenon- A Later Stage Story

Apr 18, 2025, 3:36 AM EDT - 9 months ago

Xenon- A Later Stage Story


Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data

Apr 4, 2025, 4:23 PM EDT - 10 months ago

Xenon Pharmaceuticals Looks Attractive Before Epilepsy Data


Xenon to Present at Stifel 2025 Virtual CNS Forum

Mar 12, 2025, 4:01 PM EDT - 11 months ago

Xenon to Present at Stifel 2025 Virtual CNS Forum


Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript

Feb 27, 2025, 11:53 PM EST - 11 months ago

Xenon Pharmaceuticals Inc. (XENE) Q4 2024 Earnings Call Transcript


Xenon to Present at the 45th Annual TD Cowen Healthcare Conference

Feb 25, 2025, 4:01 PM EST - 11 months ago

Xenon to Present at the 45th Annual TD Cowen Healthcare Conference


Xenon Outlines Key Corporate Milestone Opportunities for 2025

Jan 13, 2025, 8:30 AM EST - 1 year ago

Xenon Outlines Key Corporate Milestone Opportunities for 2025


Xenon to Showcase New Long-Term Azetukalner Data at AES 2024

Nov 25, 2024, 8:30 AM EST - 1 year ago

Xenon to Showcase New Long-Term Azetukalner Data at AES 2024


Xenon Reports Q3 2024 Financial Results and Business Update

Nov 12, 2024, 4:01 PM EST - 1 year ago

Xenon Reports Q3 2024 Financial Results and Business Update


Xenon Reports Q2 2024 Financial Results and Business Update

Aug 8, 2024, 4:01 PM EDT - 1 year ago

Xenon Reports Q2 2024 Financial Results and Business Update


hornetsnest23
hornetsnest23 Jan. 12 at 9:35 PM
$XENE Anyone else listen to today's JPM presentation?
1 · Reply
elmono
elmono Jan. 5 at 9:11 PM
$XENE $KURA $CRVS $KYTX I want my BO…anyone of these will do
0 · Reply
Quantumup
Quantumup Jan. 5 at 1:41 PM
Cantor⬆️ $XENE's PT to $55 from $45 and reiterated at an Overweight rating. $PRAX $BHVN $RAPP $NBIX JAZZ Cantor said in its note: Our "house view" is that most of the incremental value from current levels comes from the rest of the pipeline and not from seizures, so we're generally agnostic wrt XTOLE-2 as a catalyst. We also note that azetukalner exclusivity, while long-dated, will be driven more by polymorph, dosing and method patents. As such it may take 7-8 years to get a clearer sense of when generics might enter. However, azetukalner for seizures provides at least a strong valuation framework support, giving us cheap or free calls on the P3 depression program and the earlier stage programs highlighted above. Given their potentially transformational natures, these are programs we're keen to follow and make XENE a name with a compelling risk/reward profile over the long term, in our view.
0 · Reply
JFais
JFais Dec. 31 at 2:26 PM
agree re the LT story a better drug catches up (generally speaking) re $BHVN vs $XENE in meantime, a first mover often does quite well. See $SNDX in menin good example- agree in the LT frontline winners likely pharma, but in meantime 2026 to 2028+ Revuforj sales accelerating (& some off label)
1 · Reply
BioTechHealthX
BioTechHealthX Dec. 31 at 2:11 PM
$XENE Xenon Pharmaceuticals Inc. (NASDAQ:XENE) is expanding its lead drug beyond epilepsy into major depressive disorder and bipolar depression, potentially unlocking a much larger market for its precision neuroscience platform. https://biotechhealthx.com/biotech-news/from-rare-epilepsy-to-mental-health-why-xenon-pharmaceuticals-xene-is-expanding-fast/
0 · Reply
JFais
JFais Dec. 31 at 1:21 PM
one hurdle for $BHVN in Kv7 is $XENE has many more years' worth of patient data (huge gap in the race) Kind of reminds me of $NUVL in ROS1 chasing $NUVB in frontline ROS1 NSCLC (hard to overcome the 1st mover advantage, needs several more years to put out something comparable)
1 · Reply
JFais
JFais Dec. 31 at 1:21 PM
$XENE - Brief revisit ahead of early 2026 phase 3 epilepsy data $BHVN https://seekingalpha.com/instablog/440063-jonathan-faison/6242632-across-the-biotech-universe-xene?source=tweet
0 · Reply
JFais
JFais Dec. 31 at 1:22 AM
$XENE (NP) Across The Biotech Universe: Xenon Pharmaceuticals (brief revisit ahead of early 2026 phase 3 epilepsy data) $BHVN https://seekingalpha.com/instablog/440063-jonathan-faison/6242632-across-the-biotech-universe-xene?source=tweet
0 · Reply
Quantumup
Quantumup Dec. 26 at 1:31 PM
Stifel reit $XENE Buy-$60/said—We're reiterating our Buy rating on XENE on the back of BHVN's Kv7 failing in MDD. $BHVN $PRAX $JAZZ NBIX $RAPP Stifel added: Bottom line: we continue to believe that there's limited evidence suggesting that BHVN's Kv7 compound (BHV-7000) will be as efficacious as XEN1101. To be fair, MDD itself is risky and not yet de-risked for the Kv7 class -- it's still possible that Kv7s (including BHV-7000) end up having more limited utility in neuropsych, even if the mechanism is de-risked in FOS/epilepsy. That said, for BHV-7000 specifically, we continue to believe that to date, there's limited evidence of meaningful pharmacodynamic effect in the CNS: (1) we view prior EEG data as uninterpretable -- at the very least, less relevant to efficacy on actual seizures, and (2) we also believe the very clean AE/safety data of BHV-7000 raises the question of whether the drug is behaving like a potent anti-epileptic in the brain; we are skeptical of the GABA-selectivity thesis.
0 · Reply
LilySanders
LilySanders Dec. 26 at 1:18 PM
$XENE biotech tape stabilizing after reset looking for quiet accumulation and base
0 · Reply
hegdaom
hegdaom Dec. 26 at 1:01 PM
0 · Reply
DonCorleone77
DonCorleone77 Dec. 26 at 12:00 PM
$BHVN $XENE William Blair views Biohaven depression miss as disappointing William Blair analyst Myles Minter keeps a Market Perform rating on Biohaven after the company's Phase II study miss for BHV-7000 in major depression disorder. While disappointing, William Blair was cautious into the study given difficulties in depression clinical trial execution and placebo creep in trials over recent years, the analyst tells investors in a research note. The firm looks to the pivotal data for BHV-7000 in focal onset epilepsy in first half of 2026 as a key data point to determine if the extended-release formulation of the drug is an active formulation. It sees limited negative readthrough to Xenon Pharmaceuticals' (XENE) depression study from Biohaven's miss.
0 · Reply
DonCorleone77
DonCorleone77 Dec. 26 at 11:59 AM
$BHVN $XENE Xenon positive thesis intact following Biohaven study failure, says Jefferies Jefferies was "unsurprised" to see Biohaven's (BHVN) report mixed Phase 2 data in major depressive disorder, but believes the drug profile differs fundamentally from Xenon Pharmaceuticals' (XENE) own oral Kv7 drug, azetukalner, which has already shown best-in-class efficacy in focal epilepsy and a positive signal in MDD, the analyst tells investors. Opakalim's MDD failure should be idiosyncratic, rather than a Kv7 class effect, argues the analyst, who thinks any Xenon stock weakness could be a buying opportunity into the company's Phase 3 epilepsy data due in early 2026. Jefferies keeps a Buy rating and $65 price target on Xenon shares.
0 · Reply
notreload_ai
notreload_ai Dec. 26 at 11:49 AM
Although $BHVN BHV-7000 failed, analysts remain focused on the company's upcoming epilepsy data and believe it will have a "limited impact" on $XENE
0 · Reply
GoldStandardV2
GoldStandardV2 Dec. 25 at 10:40 AM
$XENE Expectations are shifting from future promises toward demonstrated capability. The company must show that scale translates into durable margins rather than fragility. Missed checkpoints may compound into higher capital costs. Investors will likely wait for pattern recognition before re‑committing capital.
0 · Reply
hometablet
hometablet Dec. 19 at 4:56 AM
$XENE Options ratio show bullish.
0 · Reply
OptionRunners
OptionRunners Dec. 17 at 8:30 PM
$XENE looks like 1,500 of the April $60 calls got sold (short) for $4.41. Check the change in OI for confirmation. Bear seagulls still in the OI.
0 · Reply
JarvisFlow
JarvisFlow Dec. 11 at 5:12 PM
Wells Fargo updates rating for Xenon Pharmaceuticals ( $XENE ) to Overweight, target set at 44 → 48.
0 · Reply
BillionerOfKing
BillionerOfKing Dec. 11 at 1:01 AM
$XENE Current Stock Price: $43.44 Contracts to trade: $40 XENE Dec 19 2025 Call Entry: $2.30 Exit: $3.66 ROI: 59% Hold ~21 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
biotech
biotech Dec. 9 at 2:41 PM
$SGMO CANTOR $XENE 'Sleeper program': #Nav1_7 inhibitor for #pain Status: P1 Potential peak sales: $5B re $SGMO pain NAV1.7 "sleeper program" for sure too ...
1 · Reply
Quantumup
Quantumup Dec. 9 at 1:57 PM
Citizens y'day reiterated $RAPP Market Outperform-$80 and said, 'New Data and Analyses Reinforce our Belief in the Best-In-Class Profile of RAP-219.' $PRAX $XENE $BHVN $JAZZ H.C. Wainwright⬆️the PT to $40 from $34 and reit'd at Buy after recent '219 data and said, these additional analyses reinforce our belief that RAP-219 is perhaps the most potent ASM ever seen and has a lot of dosing flexibility in Phase 3 to further improve its risk/benefit profile. At the AES conference, we also sensed widespread physicians' enthusiasm for new therapies and a much more favorable reimbursement environment for branded ASMs, suggesting a growing market in early-line FOS patients. For example, epileptologists and neurologists attending the AES told us they had prescribed cenobamate as a 2L therapy after Keppra (levetiracetam) with little pushback from payers. As a result, we increase our estimated market size of refractory FOS, taking our PT to $40 from $34.
0 · Reply
OptionRunners
OptionRunners Dec. 8 at 6:51 PM
$XENE bear seagulls
1 · Reply