Market Cap 5.62B
Revenue (ttm) 130.13M
Net Income (ttm) -260.60M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -200.26%
Debt to Equity Ratio 0.00
Volume 624,900
Avg Vol 729,006
Day's Range N/A - N/A
Shares Out 63.62M
Stochastic %K 98%
Beta 2.38
Analysts Strong Sell
Price Target $104.57

Company Profile

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, and Bardet-Biedl and Alström syndrome. It is in Phase 3 clinical trials for treating POMC or LEPR heterozygous deficiency obesities, steroid r...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 264 4280
Fax: 857 264 4299
Address:
222 Berkeley Street, 12th Floor, Boston, United States
Olliegggg
Olliegggg Aug. 5 at 12:12 AM
Where do we think $RYTM is reaching tomorrow? I’m hearing of BIG news tomorrow and some reporters are even saying potentially $110
1 · Reply
abcdzepeda
abcdzepeda Aug. 4 at 6:07 PM
$RYTM will we miss or beat earnings tomorrow?
0 · Reply
PennyPoacher
PennyPoacher Aug. 2 at 4:07 AM
$RYTM love seeing this one BANG!, it should be. I had to pick between this and Swtx about a year ago and sold my RYTM, instead of Swtx. kicking myself now. Well done longs!
0 · Reply
twincam
twincam Aug. 2 at 3:37 AM
$RYTM Rhythm is driving renewed investor excitement as its oral MC4R candidate, Bivamelagon, gained compelling Phase 2 traction. The comprehensive pipeline—anchored by the commercial-stage setmelanotide—combined with institutional demand and upcoming earnings, positions RYTM as one of the more visible rare disease biotech stories in 2025.
0 · Reply
ChessGM
ChessGM Aug. 2 at 3:23 AM
$RYTM "Heads up alert! Upcoming earnings on Tuesday, 8/5/2025 for $RYTM Bullish (7.8) --- Rhythm Pharmaceuticals, Inc. (NASDAQ: RYTM) is demonstrating significant momentum in the biopharmaceutical sector, particularly with its recent developments in obesity treatment. The stock has recently experienced a substantial surge of 36.6% following the positive results from its Phase II trial of bivamelagon, which showed strong efficacy in reducing BMI and hunger in patients with acquired hypothalamic obesity. This trial success has propelled investor confidence, as the company plans to engage with regulatory bodies like the FDA and EMA for further trials. The pricing of an upsized public offering indicates strong market interest, further supporting the bullish outlook. Financially, Rhythm Pharmaceuticals has been navigating challenges with its current product lineup, but the promising data from its pipeline could catalyze future revenue growth. The company's P/E ratio remains an area of concern, indicative of the nascent revenue streams and ongoing R&D investments typical for a company at this stage. However, the potential market for obesity treatments, particularly in rare neuroendocrine conditions, presents a lucrative growth avenue. Compared to industry peers, Rhythm's innovation in MC4R agonists positions it uniquely, though it faces stiff competition from larger players like Eli Lilly and Novo Nordisk in the broader weight management market. --- Upcoming Earnings Report: Rhythm Pharmaceuticals is slated to release its second quarter 2025 financial results on August 5, 2025. Expectations are tempered, with forecasts suggesting a decline in earnings. Historically, the company has struggled to meet earnings expectations, often due to high R&D costs and limited product revenue. Analyst consensus estimates have not been overly optimistic, reflecting these challenges. Nonetheless, the recent trial success could provide a positive narrative, potentially impacting stock performance if investor sentiment focuses on long-term growth prospects rather than immediate financials. --- Sector Performance: The healthcare sector, to which Rhythm Pharmaceuticals belongs, has shown mixed performance recently. While there are pockets of growth driven by innovation and new treatment approvals, the sector has been generally soft, influenced by broader market conditions and regulatory uncertainties. Notably, the surge in RYTM's stock is a standout within the sector, driven by company-specific advancements rather than sector-wide trends. The broader market's focus on biopharmaceuticals related to obesity and rare diseases could provide a tailwind for companies like Rhythm, which are innovating in these high-need areas. - Funds were net sellers of $RYTM during the previous reporting quarter. - Funds with large holdings in $RYTM include: - RA Capital Management LLC, MV: $322MM. Fund Rank: 58% www.racap.com - Baker Brothers Advisors LP, MV: $297MM. Fund Rank: 72% - Perceptive Advisors LLC, MV: $135MM. Fund Rank: 61% www.perceptivelife.com - Westfield Capital Management Company LP, MV: $71MM. New position. Fund Rank: 83% www.westfieldcapital.com - Alkeon Capital Management LLC, MV: $43MM. Fund Rank: 94% www.alkeoncapital.com - Last 10 days performance: -3% - Last 30 days performance: 27% - Last 90 days performance: 33% Some of the latest news articles: - Title: Canaccord Genuity Maintained a Buy Rating on Rhythm Pharmaceuticals (RYTM) Publication Date: 8/1/2025 10:46:50 AM, Source: yahoo URL: https://finance.yahoo.com/news/canaccord-genuity-maintained-buy-rating-104650110.html?.tsrc=rss - Title: Exact Sciences (EXAS) Expected to Beat Earnings Estimates: Can the Stock Move Higher? Publication Date: 7/30/2025 2:00:39 PM, Source: yahoo URL: https://finance.yahoo.com/news/exact-sciences-exas-expected-beat-140039746.html?.tsrc=rss - Title: Earnings Preview: Rhythm Pharmaceuticals, Inc. (RYTM) Q2 Earnings Expected to Decline Publication Date: 7/29/2025 2:00:10 PM, Source: yahoo URL: https://finance.yahoo.com/news/earnings-preview-rhythm-pharmaceuticals-inc-140010226.html?.tsrc=rss - Title: Rhythm Pharmaceuticals to Report Second Quarter 2025 Financial Results on Tuesday, August 5, 2025 Publication Date: 7/22/2025 8:01:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/rhythm-pharmaceuticals-report-second-quarter-200100618.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
Doozio
Doozio Jul. 24 at 10:30 AM
$XBI wen all da $DRUG zzzz go in $RYTM and $HRMY n this gets $LGND ary in 🐒🍌🧠⏰♾️
0 · Reply
abcdzepeda
abcdzepeda Jul. 22 at 9:47 PM
$RYTM if, we can get to 95 before our earnings report we may be able to hit 100 after the earnings report. Rhythm Pharmaceuticals to Report Second Quarter 2025 Financial Results on Tuesday, August 5, 2025
0 · Reply
Edwadrteu
Edwadrteu Jul. 19 at 4:44 AM
$RYTM strong bounce today. Might see follow-through.
0 · Reply
JarvisFlow
JarvisFlow Jul. 18 at 2:15 PM
Canaccord Genuity has adjusted their stance on Rhythm Pharmaceuticals ( $RYTM ), setting the rating to Buy with a target price of 92 → 105.
0 · Reply
only21million
only21million Jul. 17 at 2:13 PM
$RYTM 🚨 July 8: $66 July 10: $94 Congrats Rhythm Bulls! $SPY $QQQ $IBB
1 · Reply
Latest News on RYTM
Rhythm Pharmaceuticals: Buying This Rare Genetic Obesity Maven

Feb 25, 2025, 11:21 AM EST - 5 months ago

Rhythm Pharmaceuticals: Buying This Rare Genetic Obesity Maven


Olliegggg
Olliegggg Aug. 5 at 12:12 AM
Where do we think $RYTM is reaching tomorrow? I’m hearing of BIG news tomorrow and some reporters are even saying potentially $110
1 · Reply
abcdzepeda
abcdzepeda Aug. 4 at 6:07 PM
$RYTM will we miss or beat earnings tomorrow?
0 · Reply
PennyPoacher
PennyPoacher Aug. 2 at 4:07 AM
$RYTM love seeing this one BANG!, it should be. I had to pick between this and Swtx about a year ago and sold my RYTM, instead of Swtx. kicking myself now. Well done longs!
0 · Reply
twincam
twincam Aug. 2 at 3:37 AM
$RYTM Rhythm is driving renewed investor excitement as its oral MC4R candidate, Bivamelagon, gained compelling Phase 2 traction. The comprehensive pipeline—anchored by the commercial-stage setmelanotide—combined with institutional demand and upcoming earnings, positions RYTM as one of the more visible rare disease biotech stories in 2025.
0 · Reply
ChessGM
ChessGM Aug. 2 at 3:23 AM
$RYTM "Heads up alert! Upcoming earnings on Tuesday, 8/5/2025 for $RYTM Bullish (7.8) --- Rhythm Pharmaceuticals, Inc. (NASDAQ: RYTM) is demonstrating significant momentum in the biopharmaceutical sector, particularly with its recent developments in obesity treatment. The stock has recently experienced a substantial surge of 36.6% following the positive results from its Phase II trial of bivamelagon, which showed strong efficacy in reducing BMI and hunger in patients with acquired hypothalamic obesity. This trial success has propelled investor confidence, as the company plans to engage with regulatory bodies like the FDA and EMA for further trials. The pricing of an upsized public offering indicates strong market interest, further supporting the bullish outlook. Financially, Rhythm Pharmaceuticals has been navigating challenges with its current product lineup, but the promising data from its pipeline could catalyze future revenue growth. The company's P/E ratio remains an area of concern, indicative of the nascent revenue streams and ongoing R&D investments typical for a company at this stage. However, the potential market for obesity treatments, particularly in rare neuroendocrine conditions, presents a lucrative growth avenue. Compared to industry peers, Rhythm's innovation in MC4R agonists positions it uniquely, though it faces stiff competition from larger players like Eli Lilly and Novo Nordisk in the broader weight management market. --- Upcoming Earnings Report: Rhythm Pharmaceuticals is slated to release its second quarter 2025 financial results on August 5, 2025. Expectations are tempered, with forecasts suggesting a decline in earnings. Historically, the company has struggled to meet earnings expectations, often due to high R&D costs and limited product revenue. Analyst consensus estimates have not been overly optimistic, reflecting these challenges. Nonetheless, the recent trial success could provide a positive narrative, potentially impacting stock performance if investor sentiment focuses on long-term growth prospects rather than immediate financials. --- Sector Performance: The healthcare sector, to which Rhythm Pharmaceuticals belongs, has shown mixed performance recently. While there are pockets of growth driven by innovation and new treatment approvals, the sector has been generally soft, influenced by broader market conditions and regulatory uncertainties. Notably, the surge in RYTM's stock is a standout within the sector, driven by company-specific advancements rather than sector-wide trends. The broader market's focus on biopharmaceuticals related to obesity and rare diseases could provide a tailwind for companies like Rhythm, which are innovating in these high-need areas. - Funds were net sellers of $RYTM during the previous reporting quarter. - Funds with large holdings in $RYTM include: - RA Capital Management LLC, MV: $322MM. Fund Rank: 58% www.racap.com - Baker Brothers Advisors LP, MV: $297MM. Fund Rank: 72% - Perceptive Advisors LLC, MV: $135MM. Fund Rank: 61% www.perceptivelife.com - Westfield Capital Management Company LP, MV: $71MM. New position. Fund Rank: 83% www.westfieldcapital.com - Alkeon Capital Management LLC, MV: $43MM. Fund Rank: 94% www.alkeoncapital.com - Last 10 days performance: -3% - Last 30 days performance: 27% - Last 90 days performance: 33% Some of the latest news articles: - Title: Canaccord Genuity Maintained a Buy Rating on Rhythm Pharmaceuticals (RYTM) Publication Date: 8/1/2025 10:46:50 AM, Source: yahoo URL: https://finance.yahoo.com/news/canaccord-genuity-maintained-buy-rating-104650110.html?.tsrc=rss - Title: Exact Sciences (EXAS) Expected to Beat Earnings Estimates: Can the Stock Move Higher? Publication Date: 7/30/2025 2:00:39 PM, Source: yahoo URL: https://finance.yahoo.com/news/exact-sciences-exas-expected-beat-140039746.html?.tsrc=rss - Title: Earnings Preview: Rhythm Pharmaceuticals, Inc. (RYTM) Q2 Earnings Expected to Decline Publication Date: 7/29/2025 2:00:10 PM, Source: yahoo URL: https://finance.yahoo.com/news/earnings-preview-rhythm-pharmaceuticals-inc-140010226.html?.tsrc=rss - Title: Rhythm Pharmaceuticals to Report Second Quarter 2025 Financial Results on Tuesday, August 5, 2025 Publication Date: 7/22/2025 8:01:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/rhythm-pharmaceuticals-report-second-quarter-200100618.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
Doozio
Doozio Jul. 24 at 10:30 AM
$XBI wen all da $DRUG zzzz go in $RYTM and $HRMY n this gets $LGND ary in 🐒🍌🧠⏰♾️
0 · Reply
abcdzepeda
abcdzepeda Jul. 22 at 9:47 PM
$RYTM if, we can get to 95 before our earnings report we may be able to hit 100 after the earnings report. Rhythm Pharmaceuticals to Report Second Quarter 2025 Financial Results on Tuesday, August 5, 2025
0 · Reply
Edwadrteu
Edwadrteu Jul. 19 at 4:44 AM
$RYTM strong bounce today. Might see follow-through.
0 · Reply
JarvisFlow
JarvisFlow Jul. 18 at 2:15 PM
Canaccord Genuity has adjusted their stance on Rhythm Pharmaceuticals ( $RYTM ), setting the rating to Buy with a target price of 92 → 105.
0 · Reply
only21million
only21million Jul. 17 at 2:13 PM
$RYTM 🚨 July 8: $66 July 10: $94 Congrats Rhythm Bulls! $SPY $QQQ $IBB
1 · Reply
biolover
biolover Jul. 15 at 6:04 PM
$GPCR $RYTM $SLNO $SRRK $VKTX RYTM drug ( which is simple receptor inhibitor ) is for $400 000 per year for wt loss and not to cure the condition . This is the woke mind virus in health system. Don’t know who would feel comfortable from BP with this price long term.
2 · Reply
Quantumup
Quantumup Jul. 15 at 5:36 PM
BofA⬆️ $RYTM PT to $109 from $95 after speaking w/ KOL and said, "Improved tolerability with next-gen oral could expand HO market oppy; Reit. Buy—Positive readthrough to next-gen weekly MC4R agonist." $VKTX $GPCR LLY NVO $SRRK $SLNO AARD BofA additionally said in its note to investors:
0 · Reply
TeeMan123
TeeMan123 Jul. 15 at 2:57 PM
$RYTM prediction: company reads out positive proof of concept for PWS in Q4; gets bought out by Roche going into JPM healthcare conference in Jan 2026 @ $170ISH
2 · Reply
Tumble51
Tumble51 Jul. 13 at 5:51 PM
$ALNY $CADL $RYTM Let’s get an instant replay on Cadl, shall we ? On the. 6 yard line 3rd down , Tak reverts to social media for the 1st down, with 4 yards to go for a 1st down … Cadl fcuks up again , ball on the $5 Haha No GOAT here, call Brady !! lol
3 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jul. 11 at 7:28 PM
$ZVRA is up 27% the last 2 weeks. We track all commercial-stage oncology & non-oncology focused bios via graphs like the one attached. ZVRA is the only subject bio in this peer group with a graph that reads like this the last 2 weeks (absent those with specific catalysts or inflections points like $VRNA $INSM & $RYTM). This is not investment advice because we do not follow ZVRA in any great detail. For all we know there was a specific ZVRA catalyst. Otherwise, this trading pattern is, at best, unusual or... $XBI
2 · Reply
Quantumup
Quantumup Jul. 11 at 5:39 PM
Goldman Sachs, on 7/10, resumed $RYTM Buy/$97 $SLNO $AARD LLY $VKTX $GPCR SRRK Goldman Sachs said in their note:
0 · Reply
Quantumup
Quantumup Jul. 11 at 1:29 PM
To be fair to the Goldman analyst, she did move to a Buy/$28 on $RYTM 1 month later, while stock was around $8, but the point is she writes a Very Bullish note on $TGTX, similar to $RYTM, but maybe forget to move to Buy and⬆️PT ? I don't know. I just see a Bullish $TGTX note, w/ a lot of info that points to a higher share price for $TGTX. I really should have added that in the post below, to be fair to her. She's a good analyst, imo.
0 · Reply
Tumble51
Tumble51 Jul. 11 at 12:37 PM
$ALNY $CADL $RYTM no objective of mine , another myth by begrudged shareholders against the truth, and in addition to TAK TALES told on social media by TAK , at $CADL !! Read below , the truth , of better run biotechs posted today ⬇️ Some CADL holders have the blinders on to the truth OR:
0 · Reply
Tumble51
Tumble51 Jul. 11 at 12:07 PM
$CADL ..knock yourself out !!! $CADL lacks the ability to create value. Petrie Dishes and trials don’t make winners Results do !!! $ALNY …read it and weep ($40 in 2021…$320 today ) $RYTM …read it and weep ($3 in 2022….$88 today ) WHY ????? credible and bright CEO’s at both !! NOT ON SOCIAL MEDIA with a pumping scenario Cadl $4 in 2023 …$6 today …POOR MGMT, POOR CEO Read the facts and weep CADL Lovers ….Big Money is elsewhere !!!! Not buying penny candy or Mary Jane’s DAH @FreedSage2013
2 · Reply
Quantumup
Quantumup Jul. 11 at 11:17 AM
Goldman Sachs, on 7/10, resumed $TGTX Neutral-$37. $RHHBY $NVS $BIIB SNY TEVA This report is "Very Bullish," for a Neutral-$37. Seems like this analyst made a mistake, the same type of mistake that she made on $RYTM July-2022, where I pointed to her Neutral/$6 PT, but her note was "Massively Bullish, and look at it now $94.8 high, Y'day. Anyway, GS said in its Note to investors:
1 · Reply