Jun. 18 at 5:17 PM
$BCRX This doesnt get discussed enough IMO:
May 14, 2025 16:05
Clearside’s development partner, BioCryst Pharmaceuticals, announced it has been granted authorization to initiate its first clinical trial in Australia with avoralstat, its investigational plasma kallikrein inhibitor for the treatment of diabetic macular edema (DME) delivered with Clearside’s SCS Microinjector®. BioCryst expects initial data from DME patients in 2025.
We are also very encouraged by new preclinical data from BioCryst Pharmaceuticals’ diabetic macula edema program demonstrating that the plasma kallikrein pathway may reduce vascular leakage and that there are high drug concentrations out to six months after a single dose of avoralstat delivered by suprachoroidal injection.”
