Market Cap 150.05M
Revenue (ttm) 145.24M
Net Income (ttm) -76.42M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -52.62%
Debt to Equity Ratio -0.36
Volume 750,200
Avg Vol 233,554
Day's Range N/A - N/A
Shares Out 18.31M
Stochastic %K 46%
Beta 0.21
Analysts Strong Sell
Price Target $14.67

Company Profile

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for th...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 658 0600
Address:
85 Wells Avenue, 2nd Floor, Suite 210, Newton, United States
elmono
elmono Jan. 15 at 12:07 AM
$KPTI are they doing big ass offering before p3 data release or after? Bankrupt upon p3 miss, that’s for sure. I would at least try to grab 50-75 million before, in Jan/Feb and do the 250 million raise if p3 hits….otherwise live another day to have a final chance of endo p3….gotta think strategic here
1 · Reply
CliffordCapital
CliffordCapital Jan. 14 at 8:34 PM
$KPTI broke the uptrend from beginning of December. Wow. No buyers stepping in just constant selling. Looks ugly short term. Still confident we see a major bounce before march. Holding!
1 · Reply
celebratelife
celebratelife Jan. 14 at 7:40 PM
$KPTI Manipulated walkdown + distrust in this lousy CEO Richard Paulson. Why should we trust him?
0 · Reply
celebratelife
celebratelife Jan. 14 at 6:02 PM
$KPTI Today, someone bet some thousands on the stock being above $17.24 in May but some day trade "biotech MD" bullshitter is bashing to buy lower.
0 · Reply
CliffordCapital
CliffordCapital Jan. 14 at 4:36 PM
$KPTI something weird is going on on the bid/ask. Lots of volume too today. Big block at 7.80$ indicates MM don‘t want it to move up yet.
1 · Reply
celebratelife
celebratelife Jan. 14 at 2:24 PM
$KPTI Watch out for a basher who calls himself a BIOTECH MD (sure) who's trash talking the stock about May options. I tell you, I watch the options trades at the end of almost each day, and there's one word to describe them : BULLISH - so the "Biotech MD" is full of biologic shit.
0 · Reply
CliffordCapital
CliffordCapital Jan. 13 at 4:30 PM
$KPTI check the movement of the last two candles + volume. This is accumulation.
2 · Reply
celebratelife
celebratelife Jan. 13 at 3:43 PM
$KPTI as expected short increased so price closes low to maximize return for the hedge funds at year end (higher return = more income). Karyopharm shares desperately needs Paulson to get kicked out of the company.
0 · Reply
celebratelife
celebratelife Jan. 13 at 3:12 PM
$KPTI somebody is showing 10,000 on the bid at 7.80 (150,000 shares pre-RS).
0 · Reply
CliffordCapital
CliffordCapital Jan. 12 at 6:12 PM
$KPTI nice liquidity grab.
0 · Reply
Latest News on KPTI
Karyopharm to Participate in Baird's Biotech Discovery Series

Dec 8, 2025, 7:00 AM EST - 5 weeks ago

Karyopharm to Participate in Baird's Biotech Discovery Series


Karyopharm Announces 1-for-15 Reverse Stock Split

Feb 24, 2025, 8:40 AM EST - 11 months ago

Karyopharm Announces 1-for-15 Reverse Stock Split


Karyopharm to Participate at Upcoming Investor Conferences

Sep 3, 2024, 7:00 AM EDT - 1 year ago

Karyopharm to Participate at Upcoming Investor Conferences


elmono
elmono Jan. 15 at 12:07 AM
$KPTI are they doing big ass offering before p3 data release or after? Bankrupt upon p3 miss, that’s for sure. I would at least try to grab 50-75 million before, in Jan/Feb and do the 250 million raise if p3 hits….otherwise live another day to have a final chance of endo p3….gotta think strategic here
1 · Reply
CliffordCapital
CliffordCapital Jan. 14 at 8:34 PM
$KPTI broke the uptrend from beginning of December. Wow. No buyers stepping in just constant selling. Looks ugly short term. Still confident we see a major bounce before march. Holding!
1 · Reply
celebratelife
celebratelife Jan. 14 at 7:40 PM
$KPTI Manipulated walkdown + distrust in this lousy CEO Richard Paulson. Why should we trust him?
0 · Reply
celebratelife
celebratelife Jan. 14 at 6:02 PM
$KPTI Today, someone bet some thousands on the stock being above $17.24 in May but some day trade "biotech MD" bullshitter is bashing to buy lower.
0 · Reply
CliffordCapital
CliffordCapital Jan. 14 at 4:36 PM
$KPTI something weird is going on on the bid/ask. Lots of volume too today. Big block at 7.80$ indicates MM don‘t want it to move up yet.
1 · Reply
celebratelife
celebratelife Jan. 14 at 2:24 PM
$KPTI Watch out for a basher who calls himself a BIOTECH MD (sure) who's trash talking the stock about May options. I tell you, I watch the options trades at the end of almost each day, and there's one word to describe them : BULLISH - so the "Biotech MD" is full of biologic shit.
0 · Reply
CliffordCapital
CliffordCapital Jan. 13 at 4:30 PM
$KPTI check the movement of the last two candles + volume. This is accumulation.
2 · Reply
celebratelife
celebratelife Jan. 13 at 3:43 PM
$KPTI as expected short increased so price closes low to maximize return for the hedge funds at year end (higher return = more income). Karyopharm shares desperately needs Paulson to get kicked out of the company.
0 · Reply
celebratelife
celebratelife Jan. 13 at 3:12 PM
$KPTI somebody is showing 10,000 on the bid at 7.80 (150,000 shares pre-RS).
0 · Reply
CliffordCapital
CliffordCapital Jan. 12 at 6:12 PM
$KPTI nice liquidity grab.
0 · Reply
garygb
garygb Jan. 12 at 3:45 PM
$KPTI Down 18% after a good financial report.
0 · Reply
CliffordCapital
CliffordCapital Jan. 12 at 3:39 PM
$KPTI one thing I find particularly disturbing is that every company so far like $DAWN $HRTX comes out early with Q4 projections because they are so good!! Why would you report bad/missed numbers before the actual earnings date? Huh??
2 · Reply
celebratelife
celebratelife Jan. 12 at 3:30 PM
$KPTI very low volume drop from 8.20 to 7.40. Firing Richard Paulson will make KPTI go to the moon.
0 · Reply
jdlman
jdlman Jan. 12 at 3:30 PM
$KPTI wtf . Any news here
1 · Reply
CliffordCapital
CliffordCapital Jan. 12 at 3:23 PM
$KPTI nice stop hunt. 150k for -13%. :D
0 · Reply
DARKP00L
DARKP00L Jan. 12 at 12:43 PM
$KPTI 07:41 on Jan. 12 2026 Karyopharm Therapeutics Narrows FY2025 Sales Guidance from $140.000M-$155.000M to $145.000M vs $147.830M Est #tradeideas
0 · Reply
DARKP00L
DARKP00L Jan. 12 at 12:42 PM
$KPTI 07:41 on Jan. 12 2026 Karyopharm Therapeutics Sees Q4 Sales $33.000M vs $35.846M Est #tradeideas
0 · Reply
celebratelife
celebratelife Jan. 11 at 11:31 PM
Report card of this lousy or compromised $KPTI Board led by Barry Greene and CEO Richard Paulson: 99% drop in KPTI value while the insiders, shorts, Dempseys and other entities have made a killing at the cost of us shareholders. They forgot accountability and liability!
0 · Reply
JuggernautRaider
JuggernautRaider Jan. 11 at 11:16 PM
$KPTI hope Karyopharm makes it 🚀
0 · Reply
celebratelife
celebratelife Jan. 9 at 11:56 PM
$KPTI needs to go to $15 to just be $1 pre-RSS, then to $30, then to $75, then we can start talking. Firing Richard Paulson would be the best catalyst.
0 · Reply
celebratelife
celebratelife Jan. 9 at 11:54 PM
$KPTI This is soooo Mike Mano -- he thinks everybody is as low IQ as he is, so he has to keep repeating that virtual means not in person blah blah, again and again. It's embarrassing and insulting to most people who understand what a virtual meeting means. Also, their excuse that it's only virtual because it allows more people to attend if horse shxt and dishonest. Corona is looong gone. Before then, good companies did an in-person meeting AND virtual together. But these guys don't because they don't have the guts to look at shareholders in the eyes after they burned through hundreds of millions of our money, destroyed a billion in value, lived it up on our assets (free daily catered lunches for everyone, no accountability, so much unnecessary travels, plush perks, bonuses despite decimation of value, vacation-club style "culture", even shamelessly giving away multiple $250,000++ donations to charity while losing millions of our money. So they lie, as excuse for no in-person meeting.
0 · Reply
CliffordCapital
CliffordCapital Jan. 9 at 11:38 PM
$KPTI 10$ Next Week!
1 · Reply