Mar. 13 at 5:02 PM
$SANA I am rather shocked by the results here. Remember only 5% of the islets needed for a fx cure was given. At months 9-12 we started to see C-peptide decreasing, meaning less insulin was being made by the beta cells in the islets, however here at 14 months c-peptide is now back at the initial 6 month level. I think we all expected these islets to be exhausted by now, much like islets are exhausted in type 2 diabetes from working too hard, but the opposite has happened... Why?
I am a bit dumbfounded here. I can't imagine that engraftment takes 1 year in muscle vs 4-6 weeks via the Edmonton Protocol. Maybe lower glucose stress with better control, the press release mentioned better glycemic control so maybe the beta cells are actually getting a chance to chill in regular glucose levels. Whatever the case, and I am interested in specifics there if you have a theory or I just missed it, in what's going there, but wow. 14 months out and not only working, but thriving even more.