Market Cap 1.13B
Revenue (ttm) 8.33M
Net Income (ttm) -89.30M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -1,072.03%
Debt to Equity Ratio 0.17
Volume 3,444,200
Avg Vol 7,039,028
Day's Range N/A - N/A
Shares Out 273.92M
Stochastic %K 51%
Beta 1.00
Analysts Strong Sell
Price Target $10.08

Company Profile

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for t...

Industry: Biotechnology
Sector: Healthcare
Phone: 214 612 0000
Address:
3000 Pegasus Park Drive, Suite 1430, Dallas, United States
biotech
biotech Nov. 14 at 1:40 PM
$SGMO buyout by Astellas expected ? Q: #Astellas thoughts on gene therapy development + commerc.? why end $TSHA? STRATEGIC A: "Astellas is still committed to developing gene therapy." #Astellas says "We see more platform development together with $SGMO to actually create next generation of gene therapy.” "
1 · Reply
Quantumup
Quantumup Nov. 14 at 12:45 PM
Cantor reit $TSHA OW13 $NGNE $ACAD Neurogene (NGNE, NC) reported updated Phase 1/2 data for its ICV-administered gene therapy NGN-401 in Rett syndrome (rare neurodevelopmental disorder). From our conversations, we believe investors have spent more time focusing on key differences between the approaches, although there have also been questions about how to interpret cross-data comparisons with Taysha's TSHA-102 (intrathecally administered AAV9-based gene therapy). NGNE shares closed -15% today (vs. -8% for TSHA), which we believe could be in part related to some of the treatment-related AEs that were disclosed in NGNE's release. While we believe both companies are assessing natural history datasets to understand what is deemed a milestone, skill, etc., we don't fully appreciate or understand what analysis NGNE evaluated their data against. Nor do we fully understand the statistical analysis plan NGNE has put into place to fully appreciate what is deemed a "responder" in their pivotal trial.
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Houseofsweeps
Houseofsweeps Nov. 13 at 3:03 PM
$NGNE $TSHA jumped 70% from good results. Ngne had less patients achieve more milestones and it’s down 8% today 🤣😅
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IN0V8
IN0V8 Nov. 6 at 5:56 AM
$TSHA Buy Jefferies raises target price to $11 from $9
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warren5677
warren5677 Nov. 5 at 9:56 PM
$TSHA Looks like someone wanted in.
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JarvisFlow
JarvisFlow Nov. 5 at 12:52 PM
Citizens has adjusted their stance on Taysha Gene Therapies ( $TSHA ), setting the rating to Market Outperform with a target price of 6 → 8.
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JarvisFlow
JarvisFlow Nov. 5 at 12:41 PM
Chardan Capital updates rating for Taysha Gene Therapies ( $TSHA ) to Buy, target set at 12.
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Dark_Horse_Investments
Dark_Horse_Investments Nov. 4 at 7:35 PM
$TSHA This was very good progress call this morning (05.30 west coast). 1. The company outlined the path of the Reveal (part B) trial 2. communicated intention for BLA path forward 3. And more importantly clearly outlined how part B trial will also allow for label to include pediatric patients 2 years old (the population which will benefit the most from this therapy) 4. Lastly, this therapy is largely de-risked and the FDA hurdle for approval is easily within reach. We like these odds !!! Though fully allocated, added to the position with recent realized gains. Green pastures ahead even if markets continue choppy for the next year!!!
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Magic8BallResponse
Magic8BallResponse Nov. 4 at 6:30 PM
$TSHA Needs to be approved for patients. Horrible disease
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d_risk
d_risk Nov. 4 at 6:22 PM
$TSHA - Taysha Gene Therapies Inc. Common Stock - 10Q - Updated Risk Factors TSHA’s updated risks spotlight heavy reliance on TSHA-102’s success, uncertainties in translating early clinical results to approval, challenges in trial execution, expanded legal and regulatory scrutiny, and new pressures from evolving healthcare reforms and pricing. #GeneTherapy #PricingPressure #HealthcareReform #RegulatoryScrutiny #ClinicalTrialRisk 🟢 Added 🟠 Removed https://d-risk.ai/TSHA/10-Q/2025-11-04
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Latest News on TSHA
Why Is Taysha Gene Therapies Stock Trading Higher On Thursday?

May 29, 2025, 1:06 PM EDT - 6 months ago

Why Is Taysha Gene Therapies Stock Trading Higher On Thursday?


Taysha Gene Therapies Is Showing Promise For Rett Syndrome

Jan 27, 2025, 7:53 PM EST - 10 months ago

Taysha Gene Therapies Is Showing Promise For Rett Syndrome


What's Going On With Taysha Gene Therapies Stock Tuesday?

Jun 18, 2024, 11:42 AM EDT - 1 year ago

What's Going On With Taysha Gene Therapies Stock Tuesday?


biotech
biotech Nov. 14 at 1:40 PM
$SGMO buyout by Astellas expected ? Q: #Astellas thoughts on gene therapy development + commerc.? why end $TSHA? STRATEGIC A: "Astellas is still committed to developing gene therapy." #Astellas says "We see more platform development together with $SGMO to actually create next generation of gene therapy.” "
1 · Reply
Quantumup
Quantumup Nov. 14 at 12:45 PM
Cantor reit $TSHA OW13 $NGNE $ACAD Neurogene (NGNE, NC) reported updated Phase 1/2 data for its ICV-administered gene therapy NGN-401 in Rett syndrome (rare neurodevelopmental disorder). From our conversations, we believe investors have spent more time focusing on key differences between the approaches, although there have also been questions about how to interpret cross-data comparisons with Taysha's TSHA-102 (intrathecally administered AAV9-based gene therapy). NGNE shares closed -15% today (vs. -8% for TSHA), which we believe could be in part related to some of the treatment-related AEs that were disclosed in NGNE's release. While we believe both companies are assessing natural history datasets to understand what is deemed a milestone, skill, etc., we don't fully appreciate or understand what analysis NGNE evaluated their data against. Nor do we fully understand the statistical analysis plan NGNE has put into place to fully appreciate what is deemed a "responder" in their pivotal trial.
0 · Reply
Houseofsweeps
Houseofsweeps Nov. 13 at 3:03 PM
$NGNE $TSHA jumped 70% from good results. Ngne had less patients achieve more milestones and it’s down 8% today 🤣😅
0 · Reply
IN0V8
IN0V8 Nov. 6 at 5:56 AM
$TSHA Buy Jefferies raises target price to $11 from $9
0 · Reply
warren5677
warren5677 Nov. 5 at 9:56 PM
$TSHA Looks like someone wanted in.
0 · Reply
JarvisFlow
JarvisFlow Nov. 5 at 12:52 PM
Citizens has adjusted their stance on Taysha Gene Therapies ( $TSHA ), setting the rating to Market Outperform with a target price of 6 → 8.
0 · Reply
JarvisFlow
JarvisFlow Nov. 5 at 12:41 PM
Chardan Capital updates rating for Taysha Gene Therapies ( $TSHA ) to Buy, target set at 12.
0 · Reply
Dark_Horse_Investments
Dark_Horse_Investments Nov. 4 at 7:35 PM
$TSHA This was very good progress call this morning (05.30 west coast). 1. The company outlined the path of the Reveal (part B) trial 2. communicated intention for BLA path forward 3. And more importantly clearly outlined how part B trial will also allow for label to include pediatric patients 2 years old (the population which will benefit the most from this therapy) 4. Lastly, this therapy is largely de-risked and the FDA hurdle for approval is easily within reach. We like these odds !!! Though fully allocated, added to the position with recent realized gains. Green pastures ahead even if markets continue choppy for the next year!!!
0 · Reply
Magic8BallResponse
Magic8BallResponse Nov. 4 at 6:30 PM
$TSHA Needs to be approved for patients. Horrible disease
0 · Reply
d_risk
d_risk Nov. 4 at 6:22 PM
$TSHA - Taysha Gene Therapies Inc. Common Stock - 10Q - Updated Risk Factors TSHA’s updated risks spotlight heavy reliance on TSHA-102’s success, uncertainties in translating early clinical results to approval, challenges in trial execution, expanded legal and regulatory scrutiny, and new pressures from evolving healthcare reforms and pricing. #GeneTherapy #PricingPressure #HealthcareReform #RegulatoryScrutiny #ClinicalTrialRisk 🟢 Added 🟠 Removed https://d-risk.ai/TSHA/10-Q/2025-11-04
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Johnny_443
Johnny_443 Nov. 4 at 3:20 PM
$TSHA $SLDB Always puzzled to see stock going down right after, all things considered, quite good updates...
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War_Admiral
War_Admiral Nov. 4 at 2:38 PM
$TSHA very refreshing to hear management share their insight and elaborate on the data and the in-depth discussions with the FDA. I think they have an outstanding product and TSHA knows it works no matter how the data is sliced or diced. They are producing quality results. Great conference call. We march toward BLA....
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Jestofunk
Jestofunk Nov. 3 at 9:52 PM
$TSHA as you all know it’s 3rd quarterly earnings tomorrow and they have the conference meeting tomorrow too with webchat at 8:30am eastern time. Keep holding!
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Jestofunk
Jestofunk Nov. 3 at 9:48 PM
$TSHA buy the dip
1 · Reply
WycklyTrader
WycklyTrader Nov. 3 at 6:29 PM
$CRBU announces positive phase 1 results for CB-010 Antler and CB-011 CaMMouflage, anticipating more upside momentum. $TERN gaps up following TERN-601 and TERN-701 results. CGEM due to release multiple phase 1 results soon. DCB watch: $QURE $TCRX $TSHA :...
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Dark_Horse_Investments
Dark_Horse_Investments Nov. 3 at 5:20 PM
$TSHA What is happening to our gem, down ~10? Even the skull drilling competitor, $NGNE, better suited to market its drilling services to Elon’s BORE company, is also down, bigger ~17%. $XBI is also down ~3%. Is this related to FDA, fresh concerns with gene therapies, overall biotech selloff? Kindly share any thoughts or finding… An opportunity to add TSHA!
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biotech
biotech Nov. 3 at 3:50 PM
choice of comparator $QURE is using #natural #history data for the comparator whereas each patient acting as their own control in ie $TSHA According to the #new draft #guidance, single arm trials utilizing the #participants as their own #control is an #acceptable practice $QURE FDA thinks the current #dataset for AMT-130 in Huntington's disease would #not be #sufficient for a BLA submission. potential timing of a BLA submission for AMT-130 is uncertain. And whether or not more trials/data will need to be collected
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_www_larval_com_
_www_larval_com_ Nov. 3 at 3:13 PM
$TSHA has dropped -3% lower to -14% (~2Mv) a moment ago, 11/21 options, follow for more volatility.
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Jestofunk
Jestofunk Nov. 3 at 12:58 PM
$TSHA any idea why it’s just dumped
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ChessGM
ChessGM Nov. 2 at 2:18 AM
$TSHA "Heads up alert! Only three days until Upcoming earnings on Tuesday, 11/4/2025 for $TSHA Bullish (8.2) Taysha Gene Therapies, Inc. (TSHA) is positioned favorably within the biotechnology sector, particularly following its recent strategic advancements and regulatory milestones. The company focuses on adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases, with its lead candidate, TSHA-102, targeting Rett syndrome. Taysha has regained full global rights to TSHA-102, a significant development that enhances its strategic flexibility and potential for long-term value creation. Recent clinical trial results have shown a 100% response rate in the Phase 1/2 REVEAL trial, indicating promising safety and efficacy profiles. Financially, TSHA's P/E ratio is currently not applicable due to its clinical-stage status, but the company is expected to improve its earnings per share (EPS) as it advances toward commercialization. Analysts have set a consensus price target of $9.42, reflecting optimism about the company's growth trajectory and potential market capitalization. Comparatively, Taysha's performance metrics align favorably against industry peers, suggesting robust investor interest and confidence in its developmental pipeline. Regarding upcoming earnings reports, Taysha is scheduled to release its third-quarter financial results on November 4, 2025. Analysts are keenly observing this announcement, particularly in light of the company's recent achievements and the ongoing trial for TSHA-102. Historical performance indicates volatility typical of clinical-stage biotechs, but the recent Breakthrough Therapy designation from the FDA is expected to bolster investor sentiment. Analyst consensus estimates suggest that the market will be looking for indications of revenue growth and advancements in clinical trial timelines, which could significantly impact TSHA's stock price. In the broader context, the healthcare sector has experienced a slight retreat recently, with the NYSE Health Care Index down by 0.4%. This sector-wide trend could influence investor sentiment towards Taysha, but the company's unique advancements position it as a potential outlier. The market's focus on innovative biotechnologies, particularly in gene therapy, remains strong, suggesting that Taysha could benefit from a favorable environment as it continues to progress in its clinical endeavors. - Funds were net buyers of $TSHA during the previous reporting quarter. - Funds with large holdings in $TSHA include: - RTW Investments LP, MV: $58MM. Fund Rank: 74% www.rtwfunds.com - RA Capital Management LLC, MV: $54MM. Fund Rank: 60% www.racap.com - Avoro Capital Advisors LLC, MV: $50MM. Fund Rank: 88% avorocapital.com - Point72 Asset Management LP, MV: $17MM. Fund Rank: 91% www.point72.com - Deerfield Management Co, MV: $12MM. New position. Fund Rank: 80% www.deerfield.com - Last 10 days performance: 0% - Last 30 days performance: 2% - Last 90 days performance: 89% Some of the latest news articles: - Title: Taysha Gene Therapies to Release Third Quarter 2025 Financial Results and Host Conference Call and Webcast on November 4 Publication Date: 10/28/2025 12:00:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-release-third-120000728.html?.tsrc=rss - Title: Taysha Gene Therapies Regains Full Global Rights to Lead Rett Syndrome Program TSHA-102 Publication Date: 10/26/2025 10:43:12 AM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-regains-full-104312052.html?.tsrc=rss - Title: Raymond James Initiates Strong Buy on Taysha (TSHA) Amid Rett Syndrome Trial Momentum Publication Date: 10/26/2025 10:16:24 AM, Source: yahoo URL: https://finance.yahoo.com/news/raymond-james-initiates-strong-buy-101624877.html?.tsrc=rss - Title: How Regaining Full Rights to Rett Syndrome Gene Therapy Has Changed Taysha (TSHA)’s Investment Story Publication Date: 10/18/2025 12:18:12 AM, Source: yahoo URL: https://finance.yahoo.com/news/regaining-full-rights-rett-syndrome-001812038.html?.tsrc=rss Follow us on stocktwits.com for more earnings alerts. Not a financial advice. Not a trading signal."
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dogDazeSummer
dogDazeSummer Oct. 31 at 7:19 PM
$RANI RA Capital announces 9.9% position last night and that alone is good for 40% (was 100% earlier) Bodes well for $IFRX $RYTM $FULC $TSHA
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stockmoe12
stockmoe12 Oct. 29 at 3:07 PM
$TSHA $JANX buyout soon
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