Market Cap 581.73M
Revenue (ttm) 8.33M
Net Income (ttm) -89.30M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -1,072.03%
Debt to Equity Ratio 0.77
Volume 2,187,353
Avg Vol 3,592,476
Day's Range N/A - N/A
Shares Out 214.66M
Stochastic %K 56%
Beta 0.98
Analysts Strong Sell
Price Target $8.32

Company Profile

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for t...

Industry: Biotechnology
Sector: Healthcare
Phone: 214 612 0000
Address:
3000 Pegasus Park Drive, Suite 1430, Dallas, United States
ChessGM
ChessGM Aug. 6 at 4:43 PM
$TSHA "Heads up alert! Upcoming earnings on Tuesday, 8/12/2025 for $TSHA Bullish (7.2) Taysha Gene Therapies, Inc. (TSHA) is generating significant investor interest, underscored by a series of positive assessments from major financial analysts and institutions. Notably, BofA Securities and Jefferies have both issued a 'Buy' rating, with price targets set at $8, suggesting a robust upside potential. Cantor Fitzgerald echoed this sentiment with an ""Overweight"" rating and a more ambitious price target of $13, emphasizing the promising clinical data surrounding TSHA-102, a gene therapy in development for Rett Syndrome. This optimism is further supported by the recent Zacks Rank #2 (Buy) upgrade, signaling growing confidence in the company's future earnings prospects. Despite the overall cautious outlook for the upcoming Q2 earnings, the strategic advancements in its gene therapy pipeline continue to bolster investor confidence in Taysha’s long-term growth trajectory. The company's focus on severe monogenic diseases of the CNS places it in a promising niche within the biotechnology sector, characterized by high barriers to entry and significant unmet medical needs. Upcoming Earnings Report Analysis: Taysha Gene Therapies is set to release its financial results for the second quarter of 2025 on August 12. Historically, the company has faced challenges in meeting earnings expectations, as reflected in the recent predictions of a potential negative earnings report. Analysts have highlighted the absence of key drivers for an earnings beat this quarter, which could exert downward pressure on the stock in the short term. However, the market's attention remains fixated on the company's pipeline developments rather than immediate financial performance. Consensus estimates suggest a cautious outlook, with the primary focus on strategic advancements and clinical milestones. The upcoming earnings report will be critical in providing insight into the company's operational efficiency and its ability to navigate the complex landscape of gene therapies. Sector Performance: Taysha Gene Therapies operates within the biotechnology sector, which has shown resilience amid broader market fluctuations. The sector is characterized by high volatility but also presents significant opportunities for growth, driven by innovation and advancements in medical technology. Recent trends indicate a growing interest in gene therapies, as evidenced by increased investment and research in this area. The biotechnology sector's performance has been buoyed by successful drug approvals and breakthroughs in genetic research, positioning companies like Taysha favorably for future expansion. However, the sector remains sensitive to regulatory developments, clinical trial outcomes, and competitive dynamics, which can influence individual stock performance. - Funds were net buyers of $TSHA during the previous reporting quarter. - Funds with large holdings in $TSHA include: - Avoro Capital Advisors LLC, MV: $28MM. Fund Rank: 76% avorocapital.com - RTW Investments LP, MV: $26MM. Fund Rank: 64% www.rtwfunds.com - RA Capital Management LLC, MV: $15MM. Fund Rank: 58% www.racap.com - Point72 Asset Management LP, MV: $6MM. New position. Fund Rank: 96% www.point72.com - Baker Brothers Advisors LP, MV: $6MM. Fund Rank: 72% - Last 10 days performance: 3% - Last 30 days performance: 12% - Last 90 days performance: 44% Some of the latest news articles: - Title: Taysha Gene Therapies to Release Second Quarter 2025 Financial Results and Host Conference Call and Webcast on August 12 Publication Date: 8/5/2025 8:05:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-release-second-200500006.html?.tsrc=rss - Title: Cumberland Pharmaceuticals Leads The Charge With 2 Other Prominent Penny Stocks Publication Date: 8/5/2025 6:05:15 PM, Source: yahoo URL: https://finance.yahoo.com/news/cumberland-pharmaceuticals-leads-charge-2-180515549.html?.tsrc=rss - Title: Will Taysha Gene Therapies, Inc. (TSHA) Report Negative Q2 Earnings? What You Should Know Publication Date: 8/4/2025 2:00:05 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-inc-tsha-140005424.html?.tsrc=rss - Title: Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) Publication Date: 8/1/2025 9:06:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-announces-inducement-210600054.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
King_of_Bio
King_of_Bio Aug. 6 at 3:21 PM
$TSHA I'd love to get some more shares below $2 but I'm not sure that'll happen.
0 · Reply
twin_dad
twin_dad Aug. 3 at 1:24 AM
$TSHA AAV is having a moment
0 · Reply
warren5677
warren5677 Aug. 1 at 7:55 PM
$TSHA How in the F is this red when XBI is green?
0 · Reply
vjtweet
vjtweet Aug. 1 at 7:22 PM
$TSHA has a small position.
3 · Reply
wwmeinc
wwmeinc Aug. 1 at 4:30 PM
$TSHA ....Added today to fill out the trade...all about the gene space/FDA personnel now...while we await...mgmt update soon...in my opinion only though...Good trading and glta. "We plan to submit the pivotal trial protocol and SAP as an amendment to the IND application this quarter and anticipate initiating this pivotal program in the third quarter of 2025.”
0 · Reply
bbxdlbm
bbxdlbm Aug. 1 at 1:51 PM
$TSHA 605312
0 · Reply
TheFunkyPostalClerk
TheFunkyPostalClerk Jul. 31 at 11:03 PM
$ATOS iwas told..when they get positive news biotechs usually go up?… naw that was only $TSHA that one time
0 · Reply
wwmeinc
wwmeinc Jul. 30 at 1:27 AM
$TSHA $SRPT ....As the 'FDA World Turns'.....should be the headline tomorrow....Vinay quits...maybe...this Ms Loomer maga voice got to him?...Oh well...hopefully....but not reassured that the next CBER Director will not be in the same 'mode'...hope for the best though...glta https://www.statnews.com/2025/07/29/vinay-prasad-exits-fda-marty-makary-cber-director-chief-medical-scientific-officer/
0 · Reply
King_of_Bio
King_of_Bio Jul. 29 at 1:27 PM
0 · Reply
Latest News on TSHA
Why Is Taysha Gene Therapies Stock Trading Higher On Thursday?

May 29, 2025, 1:06 PM EDT - 2 months ago

Why Is Taysha Gene Therapies Stock Trading Higher On Thursday?


Taysha Gene Therapies Is Showing Promise For Rett Syndrome

Jan 27, 2025, 7:53 PM EST - 6 months ago

Taysha Gene Therapies Is Showing Promise For Rett Syndrome


What's Going On With Taysha Gene Therapies Stock Tuesday?

Jun 18, 2024, 11:42 AM EDT - 1 year ago

What's Going On With Taysha Gene Therapies Stock Tuesday?


Taysha Gene Therapies: TSHA-102's Potential Is A 'Buy'

Nov 3, 2023, 7:41 PM EDT - 1 year ago

Taysha Gene Therapies: TSHA-102's Potential Is A 'Buy'


ChessGM
ChessGM Aug. 6 at 4:43 PM
$TSHA "Heads up alert! Upcoming earnings on Tuesday, 8/12/2025 for $TSHA Bullish (7.2) Taysha Gene Therapies, Inc. (TSHA) is generating significant investor interest, underscored by a series of positive assessments from major financial analysts and institutions. Notably, BofA Securities and Jefferies have both issued a 'Buy' rating, with price targets set at $8, suggesting a robust upside potential. Cantor Fitzgerald echoed this sentiment with an ""Overweight"" rating and a more ambitious price target of $13, emphasizing the promising clinical data surrounding TSHA-102, a gene therapy in development for Rett Syndrome. This optimism is further supported by the recent Zacks Rank #2 (Buy) upgrade, signaling growing confidence in the company's future earnings prospects. Despite the overall cautious outlook for the upcoming Q2 earnings, the strategic advancements in its gene therapy pipeline continue to bolster investor confidence in Taysha’s long-term growth trajectory. The company's focus on severe monogenic diseases of the CNS places it in a promising niche within the biotechnology sector, characterized by high barriers to entry and significant unmet medical needs. Upcoming Earnings Report Analysis: Taysha Gene Therapies is set to release its financial results for the second quarter of 2025 on August 12. Historically, the company has faced challenges in meeting earnings expectations, as reflected in the recent predictions of a potential negative earnings report. Analysts have highlighted the absence of key drivers for an earnings beat this quarter, which could exert downward pressure on the stock in the short term. However, the market's attention remains fixated on the company's pipeline developments rather than immediate financial performance. Consensus estimates suggest a cautious outlook, with the primary focus on strategic advancements and clinical milestones. The upcoming earnings report will be critical in providing insight into the company's operational efficiency and its ability to navigate the complex landscape of gene therapies. Sector Performance: Taysha Gene Therapies operates within the biotechnology sector, which has shown resilience amid broader market fluctuations. The sector is characterized by high volatility but also presents significant opportunities for growth, driven by innovation and advancements in medical technology. Recent trends indicate a growing interest in gene therapies, as evidenced by increased investment and research in this area. The biotechnology sector's performance has been buoyed by successful drug approvals and breakthroughs in genetic research, positioning companies like Taysha favorably for future expansion. However, the sector remains sensitive to regulatory developments, clinical trial outcomes, and competitive dynamics, which can influence individual stock performance. - Funds were net buyers of $TSHA during the previous reporting quarter. - Funds with large holdings in $TSHA include: - Avoro Capital Advisors LLC, MV: $28MM. Fund Rank: 76% avorocapital.com - RTW Investments LP, MV: $26MM. Fund Rank: 64% www.rtwfunds.com - RA Capital Management LLC, MV: $15MM. Fund Rank: 58% www.racap.com - Point72 Asset Management LP, MV: $6MM. New position. Fund Rank: 96% www.point72.com - Baker Brothers Advisors LP, MV: $6MM. Fund Rank: 72% - Last 10 days performance: 3% - Last 30 days performance: 12% - Last 90 days performance: 44% Some of the latest news articles: - Title: Taysha Gene Therapies to Release Second Quarter 2025 Financial Results and Host Conference Call and Webcast on August 12 Publication Date: 8/5/2025 8:05:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-release-second-200500006.html?.tsrc=rss - Title: Cumberland Pharmaceuticals Leads The Charge With 2 Other Prominent Penny Stocks Publication Date: 8/5/2025 6:05:15 PM, Source: yahoo URL: https://finance.yahoo.com/news/cumberland-pharmaceuticals-leads-charge-2-180515549.html?.tsrc=rss - Title: Will Taysha Gene Therapies, Inc. (TSHA) Report Negative Q2 Earnings? What You Should Know Publication Date: 8/4/2025 2:00:05 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-inc-tsha-140005424.html?.tsrc=rss - Title: Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) Publication Date: 8/1/2025 9:06:00 PM, Source: yahoo URL: https://finance.yahoo.com/news/taysha-gene-therapies-announces-inducement-210600054.html?.tsrc=rss Follow us on stocktwits.com and Substack (chessgmstocks.substack.com). Not a financial advice. Not a trading signal."
0 · Reply
King_of_Bio
King_of_Bio Aug. 6 at 3:21 PM
$TSHA I'd love to get some more shares below $2 but I'm not sure that'll happen.
0 · Reply
twin_dad
twin_dad Aug. 3 at 1:24 AM
$TSHA AAV is having a moment
0 · Reply
warren5677
warren5677 Aug. 1 at 7:55 PM
$TSHA How in the F is this red when XBI is green?
0 · Reply
vjtweet
vjtweet Aug. 1 at 7:22 PM
$TSHA has a small position.
3 · Reply
wwmeinc
wwmeinc Aug. 1 at 4:30 PM
$TSHA ....Added today to fill out the trade...all about the gene space/FDA personnel now...while we await...mgmt update soon...in my opinion only though...Good trading and glta. "We plan to submit the pivotal trial protocol and SAP as an amendment to the IND application this quarter and anticipate initiating this pivotal program in the third quarter of 2025.”
0 · Reply
bbxdlbm
bbxdlbm Aug. 1 at 1:51 PM
$TSHA 605312
0 · Reply
TheFunkyPostalClerk
TheFunkyPostalClerk Jul. 31 at 11:03 PM
$ATOS iwas told..when they get positive news biotechs usually go up?… naw that was only $TSHA that one time
0 · Reply
wwmeinc
wwmeinc Jul. 30 at 1:27 AM
$TSHA $SRPT ....As the 'FDA World Turns'.....should be the headline tomorrow....Vinay quits...maybe...this Ms Loomer maga voice got to him?...Oh well...hopefully....but not reassured that the next CBER Director will not be in the same 'mode'...hope for the best though...glta https://www.statnews.com/2025/07/29/vinay-prasad-exits-fda-marty-makary-cber-director-chief-medical-scientific-officer/
0 · Reply
King_of_Bio
King_of_Bio Jul. 29 at 1:27 PM
0 · Reply
wwmeinc
wwmeinc Jul. 28 at 9:19 PM
$TSHA $SRPT ....Good news for 'medical science'...FDA went with the safe stop/halt position....killed shareholders in the process(but not sure they cared about shareholders)....and now they have lifted the hold for patients that were not shown to be affected in the ambulatory setting...some might consider the back/forth unfair but the result does at least show mgmt had the data to prove that a complete hold/halt was not warranted....As a biotech investor...probably the best outcome for now...glass half-full...just some thoughts. glta https://investorrelations.sarepta.com/news-releases/news-release-details/fda-informs-sarepta-it-recommends-sarepta-remove-its-pause-and
0 · Reply
wwmeinc
wwmeinc Jul. 25 at 8:22 PM
$TSHA ...Nice BOC...1.5M...glta Recent Trades - Last 10 of 4855 More trades... Time ET Ex Price Change Volume 16:02:43 Q 2.65 0.06 143 16:02:39 Q 2.65 0.06 1,120 16:02:19 Q 2.65 0.06 2,144 16:02:01 Q 2.65 0.06 1,617 16:00:06 Q 2.65 0.06 1,487,300 16:00:02 Q 2.65 0.06 1 16:00:02 Q 2.65 0.06 100 16:00:02 Q 2.65 0.06 99 16:00:02 Q 2.65 0.06 380 16:00:00 Q 2.65 0.06 7,700
0 · Reply
Rolo2024
Rolo2024 Jul. 25 at 5:59 PM
$TSHA Article almost 2 weeks old but worth mentioning.
0 · Reply
hick0ry2
hick0ry2 Jul. 23 at 10:54 PM
$TSHA 52 wk is $3.31 1.6 gib is 4.20
0 · Reply
King_of_Bio
King_of_Bio Jul. 23 at 1:22 PM
$IMUX $GOSS $TSHA $AKBA $CMPX It's bio-season bulls. Here are my favorites as of now. As always, do your own research! Lot of opportunities to make money if know what you're doing. GLTA
1 · Reply
wwmeinc
wwmeinc Jul. 22 at 2:44 PM
$TSHA .....Might need to find a Prasad gif in a 'China shop' these days...no more trotting between the aisles these days....just a zig-zag between the aisles with a 'few' dishes getting hit in the 'process'! Thanks. glta
0 · Reply
King_of_Bio
King_of_Bio Jul. 21 at 8:05 PM
$TSHA Happy Investor here!
0 · Reply
yogi888
yogi888 Jul. 19 at 3:24 PM
$TSHA One of the best managed companies in the industry.great safety record and miraculos work.
1 · Reply
wwmeinc
wwmeinc Jul. 18 at 4:12 PM
$TSHA ....Today's srpt conf. call.....all about releasing material news in a 'timely' manner to investors and alot of questions...Are there more 'issues/events'...ie...safety issues mgmt are seeing?...Mgmt said none they are seeing...and yet they just had a conf. call 48 hrs ago....and no mention of this latest death...all the rare diseases are very very rough/deadly and gene treatments are a hope where there was no hope....no questions...just believing all investors prefer more transparency, always, from any mgmt team...Trust...hard to come by but easily lost. Just some thoughts as we await tsha data this Fall....glta
0 · Reply
theBigDollarski
theBigDollarski Jul. 17 at 6:14 PM
$TNYA finally some movement.....This should be where $TSHA is really.
1 · Reply
wwmeinc
wwmeinc Jul. 16 at 8:36 PM
$TSHA $SRPT Some clarification seems to be on the table now with this news tonight....the FDA/mgmt seems to be on the same page going forward...Black Box Warning....not great for sure...but the key is does the drug work as intended....so far it does...patient selection going to be more 'precise' now no doubt. Just some thoughts...glta U.S. FDA has requested and Sarepta has agreed to include a black box warning in the ELEVIDYS label, resolving any material issues with the ambulant population indication – Sarepta has completed an Expert Committee on a protocol for the use of additional prophylactic immunosuppression for non-ambulant patients, and will submit the protocol to FDA imminently and discuss the pathway to resume shipment of ELEVIDYS for non-ambulant patients – Company to host investor call on July 16, 2025, at 4:30 p.m. Eastern time
0 · Reply
warren5677
warren5677 Jul. 16 at 5:40 PM
$TSHA Love it when the XBI goes down 2% like yesterday, we go down 5 percent. XBI goes up 2% we dont move
0 · Reply