Silence Therapeutics Plc ADR (SLN)

$7.30 +0.05 (0.69%)
Market Cap 218.49M
Revenue (ttm) 43.26M
Net Income (ttm) -45.31M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -104.74%
Debt to Equity Ratio 0.00
Volume 385,500
Avg Vol 99,556
Day's Range N/A - N/A
Shares Out 29.93M
Stochastic %K 80%
Beta 1.39
Analysts Strong Sell
Price Target $30.50

Company Profile

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Zerlasiran (SLN360), which is in Phase II clinical trial for cardiovascular disease associated with elevated lipoprotein(a); Divesiran (SLN124), an siRNA molecule that is in Phase I clinical trial for the treat...

Industry: Biotechnology
Sector: Healthcare
Phone: 44 20 3457 6900
Address:
72 Hammersmith Road, London, United Kingdom
KevinS131
KevinS131 Oct. 27 at 11:26 AM
$SLN Huge buyout for our competition. Should bring up our value. https://www.cnbc.com/2025/10/26/novartis-avidity-biosciences-talks.html
0 · Reply
bigpictureguy
bigpictureguy Oct. 23 at 4:08 PM
$SLN I like how stealthy it is. Suits the name. 🤫
0 · Reply
LIGator
LIGator Oct. 21 at 2:39 PM
$SLN amazing recovery from very heavy premarket trading. Something is brewing.
0 · Reply
picklestickk
picklestickk Oct. 21 at 9:28 AM
$SLN got to love a 17% drop out of nowhere! who doesnt!
0 · Reply
LIGator
LIGator Oct. 20 at 8:31 PM
$SLN Now positive YTD✅ Crossed over the 50 day EMA✅ Crossed over the 200 day EMA✅ Hit the high close for 2025✅ Let’s get this back to the price it was 52 weeks ago. $18 Target 🎯
0 · Reply
Florestan
Florestan Oct. 20 at 8:14 PM
$SLN
0 · Reply
LIGator
LIGator Oct. 20 at 3:10 PM
$SLN 😎 turned positive YTD. Let’s break $7.
0 · Reply
13Tpro
13Tpro Oct. 16 at 8:19 PM
$SLN Rnai companies are soaring. Alny is the king on the mountain with a $62B mc. RNA is at $7B, and where is our Sln? -- $300M, just about cash on hands. 😒 I don't understand the math. Gltal
1 · Reply
LIGator
LIGator Oct. 15 at 2:22 PM
$SLN someone is buying a boatload of the November $7.5 calls today. Keep the momentum going.
0 · Reply
yft212
yft212 Oct. 11 at 7:01 PM
$SLN Researching. Might be a good one to get into now.
0 · Reply
Latest News on SLN
Silence Therapeutics Completes Enrollment in SANRECO Phase 2 Study of Divesiran for Polycythemia Vera (PV)

Oct 23, 2025, 7:30 AM EDT - 4 days ago

Silence Therapeutics Completes Enrollment in SANRECO Phase 2 Study of Divesiran for Polycythemia Vera (PV)

Silence Therapeutics Plc (SLN) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference Transcript

Sep 9, 2025, 10:01 PM EDT - 6 weeks ago

Silence Therapeutics Plc (SLN) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference Transcript

Silence Therapeutics to Participate in September Investor Conferences

Sep 2, 2025, 8:00 AM EDT - 7 weeks ago

Silence Therapeutics to Participate in September Investor Conferences

Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights

Aug 7, 2025, 7:30 AM EDT - 2 months ago

Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights

Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera

Jun 12, 2025, 4:01 PM EDT - 4 months ago

Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera

Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

May 8, 2025, 8:00 AM EDT - 6 months ago

Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

Silence Therapeutics Welcomes Tim McInerney to Board of Directors

May 6, 2025, 7:45 AM EDT - 6 months ago

Silence Therapeutics Welcomes Tim McInerney to Board of Directors

Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference

Mar 5, 2025, 8:00 AM EST - 8 months ago

Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference

Silence Therapeutics plc (SLN) Q4 2024 Earnings Call Transcript

Feb 28, 2025, 11:59 AM EST - 8 months ago

Silence Therapeutics plc (SLN) Q4 2024 Earnings Call Transcript

Silence Therapeutics Reports Full Year 2024 Financial Results and Provides Business Update

Feb 27, 2025, 7:30 AM EST - 8 months ago

Silence Therapeutics Reports Full Year 2024 Financial Results and Provides Business Update

Silence Therapeutics to Report Fourth Quarter and Full Year 2024 Results on February 27, 2025

Feb 13, 2025, 8:00 AM EST - 9 months ago

Silence Therapeutics to Report Fourth Quarter and Full Year 2024 Results on February 27, 2025

Top 3 Health Care Stocks That May Explode In Q4

Dec 18, 2024, 7:46 AM EST - 11 months ago

Top 3 Health Care Stocks That May Explode In Q4

OLMA

Silence Therapeutics Presents Promising Phase 1 Data in Polycythemia Vera Patients at the American Society of Hematology (ASH) Annual Meeting

Dec 9, 2024, 7:30 AM EST - 11 months ago

Silence Therapeutics Presents Promising Phase 1 Data in Polycythemia Vera Patients at the American Society of Hematology (ASH) Annual Meeting

Silence Therapeutics to Participate in Fireside Chat at Piper Sandler 36th Annual Healthcare Conference

Nov 26, 2024, 8:00 AM EST - 11 months ago

Silence Therapeutics to Participate in Fireside Chat at Piper Sandler 36th Annual Healthcare Conference

Silence Therapeutics' Zerlasiran Has Competitive Concerns: Analyst

Nov 19, 2024, 3:34 PM EST - 1 year ago

Silence Therapeutics' Zerlasiran Has Competitive Concerns: Analyst

Top 3 Health Care Stocks You'll Regret Missing In Q4

Nov 19, 2024, 7:52 AM EST - 1 year ago

Top 3 Health Care Stocks You'll Regret Missing In Q4

AMRN TERN

Silence Therapeutics Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting

Nov 18, 2024, 2:30 PM EST - 1 year ago

Silence Therapeutics Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting

Silence Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights

Nov 14, 2024, 8:00 AM EST - 1 year ago

Silence Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights

Silence Therapeutics to Participate in Fireside Chat at the Jefferies London Healthcare Conference

Nov 13, 2024, 8:00 AM EST - 1 year ago

Silence Therapeutics to Participate in Fireside Chat at the Jefferies London Healthcare Conference

Silence Therapeutics' RNAi Pipeline: Zerlasiran's Game-Changer Potential Is A 'Buy'

Sep 8, 2024, 9:13 AM EDT - 1 year ago

Silence Therapeutics' RNAi Pipeline: Zerlasiran's Game-Changer Potential Is A 'Buy'

Silence: Additional siRNA Drug Data Leads To Next Stages Of Development

Sep 5, 2024, 2:18 PM EDT - 1 year ago

Silence: Additional siRNA Drug Data Leads To Next Stages Of Development

Silence Therapeutics to Webcast Presentations at Upcoming September Investor Conferences

Aug 27, 2024, 8:00 AM EDT - 1 year ago

Silence Therapeutics to Webcast Presentations at Upcoming September Investor Conferences

Silence Therapeutics Reports Second Quarter 2024 Financial Results and Recent Business Highlights

Aug 15, 2024, 7:30 AM EDT - 1 year ago

Silence Therapeutics Reports Second Quarter 2024 Financial Results and Recent Business Highlights

Silence Therapeutics Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients

Jun 27, 2024, 7:30 AM EDT - 1 year ago

Silence Therapeutics Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients

Silence Therapeutics Achieves $2 Million Research Milestone Payment from Hansoh Pharma Collaboration

Jun 24, 2024, 8:30 AM EDT - 1 year ago

Silence Therapeutics Achieves $2 Million Research Milestone Payment from Hansoh Pharma Collaboration

Silence Therapeutics: PV Data For Consideration After ASCVD Treatment Results

Jun 21, 2024, 2:31 PM EDT - 1 year ago

Silence Therapeutics: PV Data For Consideration After ASCVD Treatment Results

Silence Therapeutics Announces Positive Topline 48-Week Data from Phase 2 Study of Zerlasiran in Patients with Elevated Lipoprotein(a)

Jun 20, 2024, 7:30 AM EDT - 1 year ago

Silence Therapeutics Announces Positive Topline 48-Week Data from Phase 2 Study of Zerlasiran in Patients with Elevated Lipoprotein(a)

Silence Therapeutics to Present at Jefferies Global Healthcare Conference

May 30, 2024, 8:30 AM EDT - 1 year ago

Silence Therapeutics to Present at Jefferies Global Healthcare Conference

Silence Therapeutics Reports First Quarter 2024 Results and Highlights Pipeline Progress

May 16, 2024, 8:30 AM EDT - 1 year ago

Silence Therapeutics Reports First Quarter 2024 Results and Highlights Pipeline Progress

Silence Therapeutics to Participate in Fireside Chat at H.C. Wainwright 2nd Annual BioConnect Investor Conference

Apr 30, 2024, 8:30 AM EDT - 1 year ago

Silence Therapeutics to Participate in Fireside Chat at H.C. Wainwright 2nd Annual BioConnect Investor Conference

Silence Therapeutics Announces Retirement of Alistair Gray from Board of Directors

Apr 29, 2024, 8:30 AM EDT - 1 year ago

Silence Therapeutics Announces Retirement of Alistair Gray from Board of Directors

Silence Therapeutics Announces JAMA Publication of Additional Phase 1 Data for Zerlasiran in Subjects with Elevated Lipoprotein(a)

Apr 8, 2024, 11:48 AM EDT - 1 year ago

Silence Therapeutics Announces JAMA Publication of Additional Phase 1 Data for Zerlasiran in Subjects with Elevated Lipoprotein(a)

Silence Therapeutics plc (SLN) Q4 2023 Earnings Call Transcript

Mar 13, 2024, 10:01 AM EDT - 1 year ago

Silence Therapeutics plc (SLN) Q4 2023 Earnings Call Transcript

Silence Therapeutics Reports Full Year 2023 Financial Results and Recent Business Highlights

Mar 13, 2024, 7:05 AM EDT - 1 year ago

Silence Therapeutics Reports Full Year 2023 Financial Results and Recent Business Highlights

Silence Therapeutics Announces Positive Topline 36-Week Data from Ongoing Phase 2 Study of Zerlasiran in Patients with High Lipoprotein(a)

Mar 13, 2024, 7:00 AM EDT - 1 year ago

Silence Therapeutics Announces Positive Topline 36-Week Data from Ongoing Phase 2 Study of Zerlasiran in Patients with High Lipoprotein(a)

Silence Therapeutics to Report Fourth Quarter and Full Year 2023 Results on March 13, 2024

Feb 28, 2024, 8:00 AM EST - 1 year ago

Silence Therapeutics to Report Fourth Quarter and Full Year 2023 Results on March 13, 2024

Silence Therapeutics: Multiple 2024 Catalysts Make This mRNA Biotech Worth A Look

Feb 24, 2024, 8:53 PM EST - 1 year ago

Silence Therapeutics: Multiple 2024 Catalysts Make This mRNA Biotech Worth A Look

Silence Therapeutics Achieves $10 Million Milestone Payment from AstraZeneca Collaboration Following the Initiation of Phase 1 Trial

Feb 23, 2024, 8:00 AM EST - 1 year ago

Silence Therapeutics Achieves $10 Million Milestone Payment from AstraZeneca Collaboration Following the Initiation of Phase 1 Trial

Silence Therapeutics Announces Oversubscribed $120 Million Private Placement

Feb 5, 2024, 8:00 AM EST - 1 year ago

Silence Therapeutics Announces Oversubscribed $120 Million Private Placement

Silence Therapeutics to Participate in Fireside Chat at Guggenheim Healthcare Talks 6th Annual Biotechnology Conference

Jan 31, 2024, 7:00 AM EST - 1 year ago

Silence Therapeutics to Participate in Fireside Chat at Guggenheim Healthcare Talks 6th Annual Biotechnology Conference

Silence Therapeutics Strengthens Executive Leadership Team with Key Appointments

Dec 1, 2023, 7:00 AM EST - 2 years ago

Silence Therapeutics Strengthens Executive Leadership Team with Key Appointments

Silence Therapeutics Highlights Recent Company Progress and Reports Third Quarter 2023 Financial Results

Nov 14, 2023, 7:00 AM EST - 2 years ago

Silence Therapeutics Highlights Recent Company Progress and Reports Third Quarter 2023 Financial Results

Silence Therapeutics to Present at Jefferies London Healthcare Conference

Nov 8, 2023, 7:00 AM EST - 2 years ago

Silence Therapeutics to Present at Jefferies London Healthcare Conference

Silence Therapeutics Announces Positive Topline Results from Phase 1 Multiple Dose Study of Zerlasiran in Subjects with High Lipoprotein(a) and Stable Atherosclerotic Cardiovascular Disease

Nov 1, 2023, 7:00 AM EDT - 2 years ago

Silence Therapeutics Announces Positive Topline Results from Phase 1 Multiple Dose Study of Zerlasiran in Subjects with High Lipoprotein(a) and Stable Atherosclerotic Cardiovascular Disease

Silence Therapeutics to Participate in Fireside Chat at Chardan's 7th Annual Genetic Medicines Conference

Sep 26, 2023, 7:00 AM EDT - 2 years ago

Silence Therapeutics to Participate in Fireside Chat at Chardan's 7th Annual Genetic Medicines Conference

Silence Therapeutics Reports Second Quarter 2023 Results

Aug 16, 2023, 7:00 AM EDT - 2 years ago

Silence Therapeutics Reports Second Quarter 2023 Results

Silence Therapeutics: No Reason For It To Fall So Much

Jul 14, 2023, 7:15 PM EDT - 2 years ago

Silence Therapeutics: No Reason For It To Fall So Much

Silence Therapeutics Achieves $4 Million in Research Milestone Payments from Hansoh Pharma Collaboration

Jul 11, 2023, 7:00 AM EDT - 2 years ago

Silence Therapeutics Achieves $4 Million in Research Milestone Payments from Hansoh Pharma Collaboration

Silence Therapeutics to Present at the Jefferies Healthcare Conference

May 31, 2023, 7:00 AM EDT - 2 years ago

Silence Therapeutics to Present at the Jefferies Healthcare Conference

Silence Therapeutics Reports First Quarter 2023 Results

May 16, 2023, 4:00 PM EDT - 2 years ago

Silence Therapeutics Reports First Quarter 2023 Results

KevinS131
KevinS131 Oct. 27 at 11:26 AM
$SLN Huge buyout for our competition. Should bring up our value. https://www.cnbc.com/2025/10/26/novartis-avidity-biosciences-talks.html
0 · Reply
bigpictureguy
bigpictureguy Oct. 23 at 4:08 PM
$SLN I like how stealthy it is. Suits the name. 🤫
0 · Reply
LIGator
LIGator Oct. 21 at 2:39 PM
$SLN amazing recovery from very heavy premarket trading. Something is brewing.
0 · Reply
picklestickk
picklestickk Oct. 21 at 9:28 AM
$SLN got to love a 17% drop out of nowhere! who doesnt!
0 · Reply
LIGator
LIGator Oct. 20 at 8:31 PM
$SLN Now positive YTD✅ Crossed over the 50 day EMA✅ Crossed over the 200 day EMA✅ Hit the high close for 2025✅ Let’s get this back to the price it was 52 weeks ago. $18 Target 🎯
0 · Reply
Florestan
Florestan Oct. 20 at 8:14 PM
$SLN
0 · Reply
LIGator
LIGator Oct. 20 at 3:10 PM
$SLN 😎 turned positive YTD. Let’s break $7.
0 · Reply
13Tpro
13Tpro Oct. 16 at 8:19 PM
$SLN Rnai companies are soaring. Alny is the king on the mountain with a $62B mc. RNA is at $7B, and where is our Sln? -- $300M, just about cash on hands. 😒 I don't understand the math. Gltal
1 · Reply
LIGator
LIGator Oct. 15 at 2:22 PM
$SLN someone is buying a boatload of the November $7.5 calls today. Keep the momentum going.
0 · Reply
yft212
yft212 Oct. 11 at 7:01 PM
$SLN Researching. Might be a good one to get into now.
0 · Reply
LIGator
LIGator Oct. 9 at 2:30 PM
$SLN looks like the break out might have legs this time. Volume on both the stock and options.
0 · Reply
ApparentBull
ApparentBull Sep. 29 at 10:49 AM
$NUAI $SLN $FOFO $TLRY $ACB
0 · Reply
JarvisFlow
JarvisFlow Sep. 16 at 11:00 AM
HC Wainwright & Co. updates rating for Silence Therapeutics ( $SLN ) to Buy, target set at 75.
1 · Reply
LIGator
LIGator Sep. 11 at 3:31 PM
$SLN one of the most bizarre stocks around. There were no post on this board for almost a month. Volume is very low, so the price can move up and down big percentages on nothing. Major Wall Street firms have huge upside price targets for SLN and the primary owners have been actively buying more shares. This is not a trading stock, rather a buy, hold and get rich stock when their test results come out.
0 · Reply
nikitatrades
nikitatrades Sep. 10 at 12:19 PM
$SLN CEO Craig Tooman: Lead drug for rare blood cancer PV (polycythemia vera) in Phase II, data due H2 2026. siRNA platform shows strong efficacy (0 phlebotomies in controlled pts). $114M cash into 2028. Seeking partner for Lp(a) cardio program ($300M+ trial). 🧬 #Biotech #Investing
0 · Reply
NVDAMillionaire
NVDAMillionaire Sep. 10 at 7:55 AM
$SLN Great piece that accurately captures SLN's current position. So if you want to refresh your understanding of SLN or learn about SLN for the first time, this is essential reading. https://beyondspx.com/quote/SLN/analysis/silence-therapeutics-unlocking-value-through-precision-rnai-and-strategic-focus-nasdaq-sln
0 · Reply
LIGator
LIGator Aug. 11 at 12:49 PM
$SLN someone woke up early and decided to pound this stock on no news? Probably time to add.
1 · Reply
JarvisFlow
JarvisFlow Aug. 8 at 12:00 PM
Chardan Capital updates rating for Silence Therapeutics ( $SLN ) to Buy, target set at 35.
0 · Reply
Felo254
Felo254 Aug. 7 at 1:47 PM
$SLN wtf
1 · Reply
LIGator
LIGator Aug. 4 at 1:02 PM
$SLN Griffiths keeps buying. Another 18K @ $6.17
0 · Reply
ngs1135
ngs1135 Jul. 25 at 4:40 PM
$SLN added more
0 · Reply
LIGator
LIGator Jul. 23 at 6:37 PM
$SLN so much Tomfuckery going on. Someone is selling well below the VWAP trying to spoof a panic. Griffith just announced he bought 25,000 shares at an average price of $6.05 in the past 2 days.
1 · Reply