Market Cap 1.23B
Revenue (ttm) 1.08M
Net Income (ttm) -71.80M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -6,648.15%
Debt to Equity Ratio 0.00
Volume 344,100
Avg Vol 327,100
Day's Range N/A - N/A
Shares Out 44.77M
Stochastic %K 44%
Beta 3.85
Analysts Strong Sell
Price Target $34.50

Company Profile

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; a...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 338 3533
Address:
250 East Grand Avenue, South San Francisco, United States
SocioCobb
SocioCobb Jan. 13 at 12:35 PM
$SEPN Kaboom!
0 · Reply
IPOtweet
IPOtweet Jan. 9 at 3:20 PM
Biotech IPOs are back: Why 2026 could mark a hot year for the sector $AKTS $SEPN $LBRJ $MPLT $EVMN $IPO #IPO https://zpr.io/RSKbRHiEVAEU
1 · Reply
MementoMori2023
MementoMori2023 Jan. 7 at 5:37 PM
0 · Reply
wnunez
wnunez Jan. 7 at 12:02 AM
$OMER Don’t let them scare you out of your shares, at least $20-$30 in a few months is very probable. After great news such as funding, acquisitions , clinical trial succces, and FDA approval, it’s a long and not always steady rise, with multiple dips as it gaps up. As many have pointed out, according to http://Sinplifywall.st fair value is $123 👀 maybe it doesn’t get that high but it will rise significantly. I’ve been lucky enough to have got on the wave for multiple months with healthcare stocks such as $SEPN and $EBS. This one is no different, be patient and accumulate of these sales if you’re capable. Best of luck 🍻
0 · Reply
IN0V8
IN0V8 Dec. 26 at 7:14 PM
$SEPN Watch Jonestrading initiates coverage with buy rating; PT $43
0 · Reply
RevelationRanger
RevelationRanger Dec. 26 at 12:31 PM
$SEPN Expectations are recalibrating toward pragmatic delivery instead of lofty projections. Efficiency initiatives must translate into measurable productivity. Evidence of repeatability is likely to change market tone. Upside remains tied to tangible progress, not assumptions.
0 · Reply
MementoMori2023
MementoMori2023 Dec. 24 at 8:10 PM
$GLUE $SEPN A week later, not too shabby.. OMER, GLUE, MLTX, SEPN pretty good calls
0 · Reply
JarvisFlow
JarvisFlow Dec. 23 at 2:09 PM
Jones Trading updates rating for Septerna ( $SEPN ) to Buy, target set at 43.
0 · Reply
Thestocktraderhubzee
Thestocktraderhubzee Dec. 19 at 12:30 PM
$SEPN Raymond James Initiates Coverage On Septerna with Strong Buy Rating, Announces Price Target of $38
0 · Reply
JarvisFlow
JarvisFlow Dec. 19 at 12:23 PM
Raymond James has updated their rating for Septerna ( $SEPN ) to Strong Buy with a price target of 38.
0 · Reply
Latest News on SEPN
Septerna's Novo Partnership Begins To Transform The Story

Nov 25, 2025, 2:58 AM EST - 7 weeks ago

Septerna's Novo Partnership Begins To Transform The Story


Septerna to Participate in Upcoming Investor Conferences

Nov 3, 2025, 8:00 AM EST - 2 months ago

Septerna to Participate in Upcoming Investor Conferences


Septerna to Present at Jefferies Global Healthcare Conference

May 29, 2025, 8:00 AM EDT - 8 months ago

Septerna to Present at Jefferies Global Healthcare Conference


Septerna to Present at TD Cowen 45th Annual Health Care Conference

Feb 26, 2025, 8:00 AM EST - 11 months ago

Septerna to Present at TD Cowen 45th Annual Health Care Conference


Septerna Prices Upsized Initial Public Offering

Oct 24, 2024, 9:47 PM EDT - 1 year ago

Septerna Prices Upsized Initial Public Offering


Biotech Septerna aims to raise up to $186 million in US IPO

Oct 21, 2024, 6:26 AM EDT - 1 year ago

Biotech Septerna aims to raise up to $186 million in US IPO


SocioCobb
SocioCobb Jan. 13 at 12:35 PM
$SEPN Kaboom!
0 · Reply
IPOtweet
IPOtweet Jan. 9 at 3:20 PM
Biotech IPOs are back: Why 2026 could mark a hot year for the sector $AKTS $SEPN $LBRJ $MPLT $EVMN $IPO #IPO https://zpr.io/RSKbRHiEVAEU
1 · Reply
MementoMori2023
MementoMori2023 Jan. 7 at 5:37 PM
0 · Reply
wnunez
wnunez Jan. 7 at 12:02 AM
$OMER Don’t let them scare you out of your shares, at least $20-$30 in a few months is very probable. After great news such as funding, acquisitions , clinical trial succces, and FDA approval, it’s a long and not always steady rise, with multiple dips as it gaps up. As many have pointed out, according to http://Sinplifywall.st fair value is $123 👀 maybe it doesn’t get that high but it will rise significantly. I’ve been lucky enough to have got on the wave for multiple months with healthcare stocks such as $SEPN and $EBS. This one is no different, be patient and accumulate of these sales if you’re capable. Best of luck 🍻
0 · Reply
IN0V8
IN0V8 Dec. 26 at 7:14 PM
$SEPN Watch Jonestrading initiates coverage with buy rating; PT $43
0 · Reply
RevelationRanger
RevelationRanger Dec. 26 at 12:31 PM
$SEPN Expectations are recalibrating toward pragmatic delivery instead of lofty projections. Efficiency initiatives must translate into measurable productivity. Evidence of repeatability is likely to change market tone. Upside remains tied to tangible progress, not assumptions.
0 · Reply
MementoMori2023
MementoMori2023 Dec. 24 at 8:10 PM
$GLUE $SEPN A week later, not too shabby.. OMER, GLUE, MLTX, SEPN pretty good calls
0 · Reply
JarvisFlow
JarvisFlow Dec. 23 at 2:09 PM
Jones Trading updates rating for Septerna ( $SEPN ) to Buy, target set at 43.
0 · Reply
Thestocktraderhubzee
Thestocktraderhubzee Dec. 19 at 12:30 PM
$SEPN Raymond James Initiates Coverage On Septerna with Strong Buy Rating, Announces Price Target of $38
0 · Reply
JarvisFlow
JarvisFlow Dec. 19 at 12:23 PM
Raymond James has updated their rating for Septerna ( $SEPN ) to Strong Buy with a price target of 38.
0 · Reply
CGRE
CGRE Dec. 17 at 6:37 PM
$SEPN https://www.marketbeat.com/instant-alerts/septerna-nasdaqsepn-coverage-initiated-at-truist-financial-2025-12-17/
0 · Reply
MementoMori2023
MementoMori2023 Dec. 16 at 1:57 PM
$OMER let me introduce you to $GLUE $SEPN , again cash from Novartis and a great pipeline with news around the corner.
0 · Reply
JarvisFlow
JarvisFlow Dec. 15 at 1:52 PM
Truist Securities updates rating for Septerna ( $SEPN ) to Buy, target set at 34.
0 · Reply
scotttrader213
scotttrader213 Dec. 1 at 12:51 PM
$SEPN $NVO Septerna, Inc. delivered a strong 3Q25, driven by partnership revenue from its transformative collaboration with Novo Nordisk.$SEPN going higher towards 35
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KittyCat888
KittyCat888 Nov. 26 at 8:57 PM
$SEPN This one was a winner for me! Long swing at 10.29. Definitely will have this on my watch list again. Gl all who are in this!
0 · Reply
GJ_Rockabilt
GJ_Rockabilt Nov. 21 at 8:37 PM
$SEPN I don't think this is ready for a Breakout, yet. In fact, I believe it's Overbought with Price divided by Sales at over 46. Three would be nice. I'll stick with my $LFWD Rewalk Robotics, thank you.
1 · Reply
StockScanners
StockScanners Nov. 20 at 2:30 AM
$SEPN keep watch if this holds above 22.25
0 · Reply
Eylonc2004
Eylonc2004 Nov. 17 at 10:05 AM
$SEPN Why did this stock go up yesterday?
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StockScanners
StockScanners Nov. 15 at 4:09 AM
$SEPN keep watch if this holds above 21.40
0 · Reply
GJ_Rockabilt
GJ_Rockabilt Nov. 14 at 5:50 PM
$SEPN It's NOT a Squeeze.
0 · Reply
LabPsycho
LabPsycho Nov. 14 at 5:36 PM
$SEPN @GothamGirl Worth repeating in part because of the use of 'buttresses'
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GothamGirl
GothamGirl Nov. 14 at 2:14 PM
$SEPN $SGMO Worth repeating...
1 · Reply