Market Cap 1.04B
Revenue (ttm) 45.95M
Net Income (ttm) -48.88M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -106.38%
Debt to Equity Ratio 0.00
Volume 218,200
Avg Vol 297,814
Day's Range N/A - N/A
Shares Out 44.91M
Stochastic %K 17%
Beta 3.50
Analysts Strong Sell
Price Target $44.43

Company Profile

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; a...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 338 3533
Address:
250 East Grand Avenue, South San Francisco, United States
TheTradeXchange
TheTradeXchange Apr. 13 at 12:00 PM
$SEPN - Septerna Announces Initiation of Phase 1 Clinical Trial of SEP-479, an Oral Small Molecule PTH1R Agonist for the Treatment of Hypoparathyroidism
0 · Reply
chole1
chole1 Apr. 10 at 7:59 PM
$SEPN High volume sell-off.. hope the Q2 P1 start for the PTH1R is all good.
0 · Reply
SuperGreenToday
SuperGreenToday Apr. 7 at 9:36 PM
$SEPN Share Price: $24.84 Contract Selected: Oct 16, 2026 $32.0 Calls Buy Zone: $6.27 – $7.75 Target Zone: $10.41 – $12.72 Potential Upside: 57% ROI Time to Expiration: 191 Days | Updates via https://fxcapta.com/stockinfo/
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erevnon
erevnon Mar. 24 at 7:05 PM
JP Morgan maintains Septerna $SEPN at Overweight and raises the price target from $34 to https://marketsblock.com/stock-upgrades-and-downgrades/
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LovePNW
LovePNW Mar. 11 at 7:50 PM
$SEPN https://www.marketbeat.com/instant-alerts/truist-financial-forecasts-strong-price-appreciation-for-septerna-nasdaqsepn-stock-2026-03-11/
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erevnon
erevnon Mar. 11 at 2:43 PM
Truist Securities maintains Septerna $SEPN at Buy and raises the price target from $34 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
shavitmi
shavitmi Mar. 6 at 1:57 PM
$TNYA if $ALNY a $40 bilion company works with TNYA i think its a home run $SEPN
0 · Reply
shavitmi
shavitmi Mar. 6 at 11:06 AM
$TNYA the deal with $ALNY remind me the deal $SEPN did with novo
0 · Reply
shavitmi
shavitmi Mar. 5 at 8:26 PM
$TNYA the deal with $ALNY remind me the deal $SEPN did with novo
1 · Reply
LovePNW
LovePNW Mar. 3 at 9:14 PM
$SEPN https://www.marketbeat.com/instant-alerts/wells-fargo-company-increases-septerna-nasdaqsepn-price-target-to-4800-2026-03-03/
0 · Reply
Latest News on SEPN
Septerna to Participate in Upcoming Investor Conferences

Nov 3, 2025, 8:00 AM EST - 5 months ago

Septerna to Participate in Upcoming Investor Conferences


Septerna to Present at Jefferies Global Healthcare Conference

May 29, 2025, 8:00 AM EDT - 11 months ago

Septerna to Present at Jefferies Global Healthcare Conference


Septerna Prices Upsized Initial Public Offering

Oct 24, 2024, 9:47 PM EDT - 1 year ago

Septerna Prices Upsized Initial Public Offering


TheTradeXchange
TheTradeXchange Apr. 13 at 12:00 PM
$SEPN - Septerna Announces Initiation of Phase 1 Clinical Trial of SEP-479, an Oral Small Molecule PTH1R Agonist for the Treatment of Hypoparathyroidism
0 · Reply
chole1
chole1 Apr. 10 at 7:59 PM
$SEPN High volume sell-off.. hope the Q2 P1 start for the PTH1R is all good.
0 · Reply
SuperGreenToday
SuperGreenToday Apr. 7 at 9:36 PM
$SEPN Share Price: $24.84 Contract Selected: Oct 16, 2026 $32.0 Calls Buy Zone: $6.27 – $7.75 Target Zone: $10.41 – $12.72 Potential Upside: 57% ROI Time to Expiration: 191 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
erevnon
erevnon Mar. 24 at 7:05 PM
JP Morgan maintains Septerna $SEPN at Overweight and raises the price target from $34 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
LovePNW
LovePNW Mar. 11 at 7:50 PM
$SEPN https://www.marketbeat.com/instant-alerts/truist-financial-forecasts-strong-price-appreciation-for-septerna-nasdaqsepn-stock-2026-03-11/
0 · Reply
erevnon
erevnon Mar. 11 at 2:43 PM
Truist Securities maintains Septerna $SEPN at Buy and raises the price target from $34 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
shavitmi
shavitmi Mar. 6 at 1:57 PM
$TNYA if $ALNY a $40 bilion company works with TNYA i think its a home run $SEPN
0 · Reply
shavitmi
shavitmi Mar. 6 at 11:06 AM
$TNYA the deal with $ALNY remind me the deal $SEPN did with novo
0 · Reply
shavitmi
shavitmi Mar. 5 at 8:26 PM
$TNYA the deal with $ALNY remind me the deal $SEPN did with novo
1 · Reply
LovePNW
LovePNW Mar. 3 at 9:14 PM
$SEPN https://www.marketbeat.com/instant-alerts/wells-fargo-company-increases-septerna-nasdaqsepn-price-target-to-4800-2026-03-03/
0 · Reply
IN0V8
IN0V8 Mar. 3 at 8:55 PM
$SEPN Buy Wells Fargo raises target price to $48 from $28
0 · Reply
erevnon
erevnon Mar. 3 at 4:25 PM
Wells Fargo maintains Septerna $SEPN at Overweight and raises the price target from $28 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
AlertsAndNews
AlertsAndNews Mar. 1 at 11:32 PM
$SEPN Septerna Announces Positive Phase 1 Data for SEP-631, an Oral MRGPRX2 NAM for the Treatment of Mast Cell-Driven Diseases, and Outlines Initial Phase 2 Development Strategy "SEP-631 Demonstrated Robust, Dose-Dependent Inhibition of Icatibant-Induced Skin Wheal Formation, with Complete Inhibition Observed at Doses as Low as 10 mg Once-Daily Well-Tolerated Across All Doses Studied with an Adverse Event Profile Comparable to Placebo; Pharmacokinetic Profile Supports Once-Daily Oral Dosing" Conference call here tomorrow morning as well. "Company to Host Conference Call and Webcast on Monday, March 2, 2026, at 8:00 a.m. ET"
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BillionerOfKing
BillionerOfKing Feb. 25 at 10:54 PM
$SEPN Current Stock Price: $29.99 Contracts to trade: $30.0 SEPN Mar 20 2026 Call Entry: $1.85 Exit: $3.42 ROI: 85% Hold ~25 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
RaymondNorman877
RaymondNorman877 Feb. 18 at 12:40 PM
$SEPN Rare-disease biotech with asymmetric upside; timeline slippage is main threat.
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OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 17 at 9:56 AM
$SEPN RSI: 56.86, MACD: 0.0744 Vol: 1.14, MA20: 25.62, MA50: 26.41 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
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BondHarbinger
BondHarbinger Feb. 4 at 2:24 PM
$SEPN is a clinical-stage biotech focused on rare diseases; its pipeline is in development, making it a high-risk, binary investment.
0 · Reply
BillionerOfKing
BillionerOfKing Feb. 3 at 2:10 AM
$SEPN Current Stock Price: $25.09 Contracts to trade: $26.0 SEPN Feb 20 2026 Call Entry: $0.85 Exit: $1.52 ROI: 79% Hold ~30 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
GJ_Rockabilt
GJ_Rockabilt Jan. 30 at 1:04 PM
$SEPN Today is last day to sign up to for FREE Warrants with every Share of Cancer fighting TPST . Acquisition in process. Do your own Due Diligence.
0 · Reply
SocioCobb
SocioCobb Jan. 23 at 10:25 PM
$SEPN Kaboomalooma!
0 · Reply
IN0V8
IN0V8 Jan. 20 at 10:46 PM
$SEPN H.C. Wainwright raises target price to $35 from $30
0 · Reply