Jul. 16 at 2:26 AM
$OMER - Parkinsons disease----Endothelial injury, particularly in the blood-brain barrier, is increasingly recognized as a potential contributor to Parkinson's disease (PD). This injury can manifest as impaired endothelial function, disrupted blood-brain barrier permeability, and altered vascular structure, potentially impacting disease progression and symptom severity.
Impaired Endothelial Function: Studies show decreased flow-mediated dilation (FMD) in PD patients, indicating impaired endothelial function. This can be linked to various factors, including mitochondrial dysfunction, oxidative stress, and traditional cardiovascular risk factors.