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Sionna Therapeutics Inc (SION)

$7.85 +0.23 (3.02%)

Overview
Financial
Short Interest
Institutional Holdings
Dividends
Charts

Market Cap	354.91M
Revenue (ttm)	0.00
Net Income (ttm)	-75.27M
EPS (ttm)	N/A
PE Ratio	0.00
Forward PE	N/A
Profit Margin	0.00%
Debt to Equity Ratio	0.00

Volume	1,210,900
Avg Vol	2,284,880
Day's Range	N/A - N/A
Shares Out	45.21M
Stochastic %K	92%
Beta	0.89
Analysts	Sell
Price Target	$5.50

Company Profile

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-...

Industry: Biotechnology

Sector: Healthcare

Phone: 617 819 2020

Website: www.sionnatx.com

Address:

21 Hickory Drive, Suite 500, Waltham, United States

pal123 Sep. 11 at 6:48 PM

$DELL $HPE $INTC check $SION

0 · Reply

fantastex Sep. 11 at 1:33 PM

$SION 8+ today smelling some buyout offer soon

0 · Reply

fantastex Sep. 10 at 8:04 PM

$SION 9 Tomorrow?

1 · Reply

fantastex Sep. 10 at 7:55 PM

$SION running hard

1 · Reply

AshLim1 Sep. 8 at 7:39 PM

$SION Been good to me no doubt but had to sell today in need of funds,however I did place a bit into SMR was I wrong answers on a post card was fun being amongst these 600 odd few left early I noticed is what it is, but I will come back to SION 😉 soon still watching

0 · Reply

topstockalerts Sep. 8 at 12:00 AM

$SION I’m starting to think this story has another chapter.

1 · Reply

JFais Sep. 7 at 11:56 AM

$IONS $SION $RARE $TENX some of the more recent ones that came to mind, feel free to add others

2 · Reply

DylanGFM Sep. 7 at 1:54 AM

$SION this is the only one I can find right now that is down 50% on the month but up 10% on the week

0 · Reply

EvCe Sep. 4 at 4:37 PM

$SION steady horse 💲💲💲

0 · Reply

fantastex Sep. 4 at 1:53 PM

$SION 20% pump anytime . Now its Just time for call killers....

0 · Reply

Robbins LLP Reminds Stockholders it is Investigating the Recent Stock Drop of Sionna Therapeutics

Aug 17, 2026, 4:20 PM EDT - 26 days ago

Robbins LLP is Investigating the Recent Stock Drop of Sionna Therapeutics; Contact the Firm for Information

Aug 16, 2026, 5:16 PM EDT - 27 days ago

SION Investors Have Opportunity to Join Sionna Therapeutics, Inc. Fraud Investigation with SBS Law

Aug 13, 2026, 12:50 PM EDT - 4 weeks ago

SION SHAREHOLDER INVESTIGATION: SueWallSt Notifies Investors of Potential Securities Claims Involving Sionna Therapeutics

2026-08-11T16:05:27.000Z - 4 weeks ago

Sionna Therapeutics rises 15.9%

Aug 11, 2026, 10:40 AM EDT - 4 weeks ago

Sionna Therapeutics, Inc. (SION) Shares Plummet Following Clinical Trial Results—Johnson Fistel Investigates

2026-08-11T14:15:10.000Z - 4 weeks ago

Sionna Therapeutics price target lowered to $5 from $38 at Freedom Broker

2026-08-11T14:05:30.000Z - 4 weeks ago

Sionna Therapeutics rises 14.0%

2026-08-10T19:55:43.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Hold from Buy at JonesResearch

2026-08-10T19:20:28.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Neutral from Buy at BTIG

2026-08-10T19:20:09.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Market Perform from Outperform at LifeSci Capital

2026-08-10T17:25:09.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Neutral at Guggenheim after trial miss

VRTX

2026-08-10T17:20:13.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Neutral from Buy at Guggenheim

2026-08-10T16:55:07.000Z - 4 weeks ago

Citizens downgrades Sionna Therapeutics as SION-719 miss questions NBD1 thesis

2026-08-10T16:06:38.000Z - 4 weeks ago

Sionna Therapeutics falls -92.0%

2026-08-10T16:06:33.000Z - 4 weeks ago

Vertex Pharmaceuticals price target raised to $672 from $605 at BofA

VRTX

Aug 10, 2026, 12:01 PM EDT - 4 weeks ago

Why Sionna Therapeutics Stock Is Crashing 92% to a Record Low

2026-08-10T15:55:44.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Market Perform from Outperform at Citizens

2026-08-10T15:55:12.000Z - 4 weeks ago

Vertex Stock (VRTX) Soars 7% as Rival Sionna (SION) Crashes 92% on Failed Drug Trial

VRTX

2026-08-10T15:30:09.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Market Perform from Strong Buy at Raymond James

2026-08-10T15:15:21.000Z - 4 weeks ago

Sionna Therapeutics upgraded to Sector Perform at RBC after 90% pullback

2026-08-10T15:00:25.000Z - 4 weeks ago

Sionna Therapeutics upgraded to Sector Perform from Underperform at RBC Capital

2026-08-10T14:40:17.000Z - 4 weeks ago

Wedbush downgrades Sionna Therapeutics to Neutral following trial setback

2026-08-10T14:30:38.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Neutral from Outperform at Wedbush

2026-08-10T14:05:50.000Z - 4 weeks ago

Sionna Therapeutics falls -91.8%

Aug 10, 2026, 9:41 AM EDT - 4 weeks ago

Sionna Therapeutics, Inc. (SION) Shares Plummet Following Clinical Trial Results - Johnson Fistel Investigates

2026-08-10T13:25:09.000Z - 4 weeks ago

Sionna Therapeutics downgraded to Hold from Buy at Stifel

Aug 10, 2026, 8:06 AM EDT - 4 weeks ago

Sionna scraps genetic disorder drug program after trial setback; shares tank

Aug 10, 2026, 8:00 AM EDT - 4 weeks ago

Sionna Therapeutics Transcript: Study result

Aug 10, 2026, 8:00 AM EDT - 4 weeks ago

Sionna Therapeutics Press release: Study result

Aug 10, 2026, 8:00 AM EDT - 4 weeks ago

Sionna Therapeutics Slides: Study result

Aug 6, 2026, 9:00 AM EDT - 5 weeks ago

Sionna Therapeutics Slides: Corporate presentation

Aug 6, 2026, 7:00 AM EDT - 5 weeks ago

Sionna Therapeutics Reports Second Quarter 2026 Financial Results

Aug 6, 2026, 7:00 AM EDT - 5 weeks ago

Sionna Therapeutics Earnings release: Q2 2026

Aug 6, 2026, 7:00 AM EDT - 5 weeks ago

Sionna Therapeutics Quarterly report: Q2 2026

Jun 10, 2026, 10:00 AM EDT - 3 months ago

Sionna Therapeutics Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

Jun 3, 2026, 12:15 PM EDT - 3 months ago

Sionna Therapeutics Transcript: Jefferies Global Healthcare Conference 2026

May 27, 2026, 8:00 AM EDT - 3 months ago

Sionna Therapeutics to Participate in Upcoming June 2026 Investor Conferences

May 20, 2026, 2:05 PM EDT - 3 months ago

Sionna Therapeutics Transcript: RBC Capital Markets Global Healthcare Conference 2026

May 13, 2026, 8:00 AM EDT - 4 months ago

Sionna Therapeutics to Participate in the 2026 RBC Capital Markets Global Healthcare Conference

May 12, 2026, 7:00 AM EDT - 4 months ago

Sionna Therapeutics Reports First Quarter 2026 Financial Results

May 12, 2026, 7:00 AM EDT - 4 months ago

Sionna Therapeutics Earnings release: Q1 2026

May 12, 2026, 7:00 AM EDT - 4 months ago

Sionna Therapeutics Quarterly report: Q1 2026

May 12, 2026, 7:00 AM EDT - 4 months ago

Sionna Therapeutics Slides: Corporate presentation

Apr 27, 2026, 8:00 AM EDT - 4 months ago

Sionna Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 8:00 AM EDT - 4 months ago

Sionna Therapeutics Proxy statement: Proxy filing

Apr 27, 2026, 7:00 AM EDT - 4 months ago

Sionna Therapeutics Completes Enrollment in PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, Added to Standard of Care in Participants with Cystic Fibrosis

Apr 7, 2026, 7:00 AM EDT - 5 months ago

Sionna Therapeutics to Participate in the Raymond James 2026 Biotech Innovation Symposium

Mar 10, 2026, 1:40 PM EDT - 6 months ago

Sionna Therapeutics Transcript: Leerink Global Healthcare Conference 2026

Mar 2, 2026, 2:30 PM EST - 6 months ago

Sionna Therapeutics Transcript: TD Cowen 46th Annual Health Care Conference

Mar 2, 2026, 7:00 AM EST - 6 months ago

Sionna Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results

Mar 2, 2026, 7:00 AM EST - 6 months ago

Sionna Therapeutics Annual report: Q4 2025

Mar 2, 2026, 7:00 AM EST - 6 months ago

Sionna Therapeutics Earnings release: Q4 2025

Mar 2, 2026, 7:00 AM EST - 6 months ago

Sionna Therapeutics Slides: Corporate presentation

Feb 23, 2026, 8:00 AM EST - 6 months ago

Sionna Therapeutics to Participate in Upcoming March 2026 Investor Conferences

Feb 11, 2026, 2:00 PM EST - 7 months ago

Sionna Therapeutics Transcript: Guggenheim Securities Emerging Outlook: Biotech Summit 2026

Feb 4, 2026, 7:00 AM EST - 7 months ago

Sionna Therapeutics to Present at the Guggenheim Securities Emerging Outlook: Biotech Summit 2026

Jan 13, 2026, 12:45 PM EST - 8 months ago

Sionna Therapeutics Transcript: 44th Annual J.P. Morgan Healthcare Conference

Jan 7, 2026, 7:00 AM EST - 8 months ago

Sionna Therapeutics Slides: Corporate presentation

Jan 5, 2026, 7:00 AM EST - 8 months ago

Sionna Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference

Dec 4, 2025, 9:45 AM EST - 9 months ago

Sionna Therapeutics Transcript: Citi Annual Global Healthcare Conference 2025

Dec 3, 2025, 12:30 PM EST - 9 months ago

Sionna Therapeutics Transcript: Evercore ISI 8th Annual HealthCONx Conference

Nov 24, 2025, 7:00 AM EST - 9 months ago

Sionna Therapeutics to Participate in Upcoming December Investor Conferences

Nov 12, 2025, 8:00 AM EST - 10 months ago

Sionna Therapeutics Transcript: Stifel 2025 Healthcare Conference

Nov 11, 2025, 8:30 AM EST - 10 months ago

Sionna Therapeutics Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Nov 5, 2025, 7:00 AM EST - 10 months ago

Sionna Therapeutics Reports Third Quarter 2025 Financial Results

Nov 5, 2025, 7:00 AM EST - 10 months ago

Sionna Therapeutics Quarterly report: Q3 2025

Nov 5, 2025, 7:00 AM EST - 10 months ago

Sionna Therapeutics Earnings release: Q3 2025

Nov 4, 2025, 8:00 AM EST - 10 months ago

Sionna Therapeutics to Participate in Upcoming November Investor Conferences

Oct 24, 2025, 1:15 PM EDT - 10 months ago

Sionna Therapeutics Announces Presentation of SION-719 and SION-451 Phase 1 Data and Poster of New Preclinical Data on the Impact of NBD1 Stabilizers on F508del-CFTR Half-Life at the 2025 North American Cystic Fibrosis Conference

Oct 21, 2025, 7:00 AM EDT - 10 months ago

Sionna Therapeutics Announces Initiation of PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, When Added to Standard of Care in Participants with Cystic Fibrosis

Oct 20, 2025, 6:00 PM EDT - 10 months ago

Sionna Therapeutics Slides: Corporate Presentation

Oct 1, 2025, 4:05 PM EDT - 11 months ago

Sionna Therapeutics to Present Data at the 2025 North American Cystic Fibrosis Conference

Sep 8, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Appoints Caroline Stark Beer as Chief Business Officer

Sep 8, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Transcript: Morgan Stanley 23rd Annual Global Healthcare Conference

Sep 3, 2025, 1:35 PM EDT - 1 year ago

Sionna Therapeutics Transcript: Cantor Global Healthcare Conference 2025

Aug 27, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics to Participate in Upcoming September Investor Conferences

Aug 25, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Announces First Subjects Dosed in Phase 1 Trial Evaluating NBD1 Stabilizer, SION-451, in Proprietary Dual Combinations in Development for the Treatment of Cystic Fibrosis

Aug 11, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Reports Second Quarter 2025 Financial Results

Aug 11, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Quarterly report: Q2 2025

Aug 11, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Earnings release: Q2 2025

Jun 11, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Transcript: Goldman Sachs 46th Annual Global Healthcare Conference 2025

Jun 6, 2025, 11:00 AM EDT - 1 year ago

Sionna Therapeutics Announces Presentation of Preclinical Data that Demonstrate Proprietary Dual Combination Therapies Enable Full CFTR Correction in CFHBE Model

Jun 4, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Transcript: Study Update

Jun 4, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Press release: Study Update

Jun 4, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Slides: Study Update

Jun 4, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Announces Positive Phase 1 Data for NBD1 Stabilizers SION-719 and SION-451 and Advances Both Programs in Clinical Development for Cystic Fibrosis

Jun 3, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics to Present at the Goldman Sachs 46th Annual Global Healthcare Conference

May 22, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics to Present Preclinical Data During Oral Session at the 48th European Cystic Fibrosis Conference

May 12, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Reports First Quarter 2025 Financial Results

May 12, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Quarterly report: Q1 2025

May 12, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Earnings release: Q1 2025

May 7, 2025, 12:30 PM EDT - 1 year ago

Sionna Therapeutics Transcript: The Citizens JMP Life Sciences Conference 2025

Apr 30, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics to Present at The Citizens Life Sciences Conference 2025

Apr 29, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Proxy statement: Proxy Filing

Apr 29, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Proxy statement: Proxy Filing

Mar 20, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Earnings release: Q4 2024

Mar 20, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Annual report: Q4 2024

Mar 20, 2025, 7:00 AM EDT - 1 year ago

Sionna Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results

Mar 3, 2025, 2:00 PM EST - 1 year ago

Sionna Therapeutics Transcript: 45th Annual TD Cowen Health Care Conference

Feb 24, 2025, 8:00 AM EST - 1 year ago

Sionna Therapeutics to Present at the 45th Annual TD Cowen Health Care Conference

Feb 10, 2025, 4:03 PM EST - 1 year ago

Sionna Therapeutics Announces Closing of $219.2 million Upsized Initial Public Offering, Including Full Exercise of Underwriters' Option to Purchase Additional Shares

Feb 6, 2025, 7:51 PM EST - 1 year ago

Sionna Therapeutics Prices Upsized Initial Public Offering

pal123 Sep. 11 at 6:48 PM

$DELL $HPE $INTC check $SION

0 · Reply

fantastex Sep. 11 at 1:33 PM

$SION 8+ today smelling some buyout offer soon

0 · Reply

fantastex Sep. 10 at 8:04 PM

$SION 9 Tomorrow?

1 · Reply

fantastex Sep. 10 at 7:55 PM

$SION running hard

1 · Reply

AshLim1 Sep. 8 at 7:39 PM

0 · Reply

topstockalerts Sep. 8 at 12:00 AM

$SION I’m starting to think this story has another chapter.

1 · Reply

JFais Sep. 7 at 11:56 AM

$IONS $SION $RARE $TENX some of the more recent ones that came to mind, feel free to add others

2 · Reply

DylanGFM Sep. 7 at 1:54 AM

$SION this is the only one I can find right now that is down 50% on the month but up 10% on the week

0 · Reply

EvCe Sep. 4 at 4:37 PM

$SION steady horse 💲💲💲

0 · Reply

fantastex Sep. 4 at 1:53 PM

$SION 20% pump anytime . Now its Just time for call killers....

0 · Reply

MrEd916 Sep. 3 at 8:00 PM

$SION Looks like no one thinks she's gonna pop again in the morning tomorrow

0 · Reply

MrEd916 Sep. 3 at 6:18 PM

$SION spike at the open and then the drift down. Waiting to see if the price will bounce back in the final hour again

0 · Reply

fantastex Sep. 3 at 6:04 PM

$SION fucking stock shall have sold Yesterday

0 · Reply

fantastex Sep. 3 at 4:01 PM

$SION boring stock

0 · Reply

tbagoni Sep. 3 at 12:45 PM

$SION Told you just to be patient! 🤑

0 · Reply

fantastex Sep. 2 at 9:52 PM

$SION lets goooook

0 · Reply

fantastex Sep. 2 at 8:45 PM

$SION my favorite actress Is sionna Miller

0 · Reply

dtankersley Sep. 2 at 6:15 PM

$SION Why didn't I buy this in the $5's last week? Anyone?

4 · Reply

fantastex Sep. 2 at 4:25 PM

$SION slowly climbing luckily no pumpers like @topstockalerts here so safe to buy!

0 · Reply

BigWaveOperator Sep. 2 at 3:25 PM

$SION why am I the only one here

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BigWaveOperator Sep. 2 at 3:04 PM

$SION wow what a pump and dump

0 · Reply

BigWaveOperator Sep. 1 at 6:27 PM

$SION really happy with my adds sub 6s

0 · Reply

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