Market Cap 1.95B
Revenue (ttm) 0.00
Net Income (ttm) -75.27M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 777,800
Avg Vol 376,054
Day's Range N/A - N/A
Shares Out 45.14M
Stochastic %K 73%
Beta 1.35
Analysts Strong Sell
Price Target $50.60

Company Profile

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 819 2020
Address:
21 Hickory Drive, Suite 500, Waltham, United States
laaarsas
laaarsas May. 6 at 9:33 PM
$SION What dose will we see in phase 2?
0 · Reply
laaarsas
laaarsas May. 6 at 1:12 PM
$SION Why is this stock valued as if the clinical outcome is almost certain?
0 · Reply
laaarsas
laaarsas May. 5 at 7:41 PM
$SION Stock already up much. How much could ph2a data move share price? Tell me
0 · Reply
laaarsas
laaarsas May. 5 at 7:31 PM
$SION Hi donkeys what is vibe in here?
0 · Reply
DARKP00L
DARKP00L May. 5 at 1:30 PM
$SION 09:24 on May. 05 2026 Wedbush Initiates Coverage On Sionna Therapeutics with Outperform Rating, Announces Price Target of $53 #tradeideas
1 · Reply
S_Franconi
S_Franconi Apr. 21 at 11:18 AM
$SION Very bullish. 59 watchers, April 21, 2026.
0 · Reply
Doozio
Doozio Apr. 19 at 5:22 PM
$SION appears ready on the DLO ONTO 🐒🍌🧠⏰♾️
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Mar. 19 at 11:48 AM
$SION RSI: 36.98, MACD: -0.6171 Vol: 1.45, MA20: 36.36, MA50: 38.33 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
BillionerOfKing
BillionerOfKing Feb. 22 at 2:53 PM
$SION Current Stock Price: $35.52
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OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 14 at 3:10 AM
$SION RSI: 36.97, MACD: -0.9642 Vol: 2.85, MA20: 40.21, MA50: 40.77 ⚪ HOLD - Sideways 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
Latest News on SION
Sionna Therapeutics initiated with an Outperform at Wedbush

2026-05-04T20:21:26.000Z - 3 days ago

Sionna Therapeutics initiated with an Outperform at Wedbush


Three new option listings on March 17th

2026-03-17T12:36:27.000Z - 7 weeks ago

Three new option listings on March 17th

GBFH OCS


Sionna Therapeutics files automatic mixed securities shelf

2026-03-02T13:34:52.000Z - 2 months ago

Sionna Therapeutics files automatic mixed securities shelf


Sionna Therapeutics files automatic mixed securities shelf

2026-03-02T13:28:22.000Z - 2 months ago

Sionna Therapeutics files automatic mixed securities shelf


Sionna Therapeutics files automatic mixed securities shelf

2026-03-02T13:23:17.000Z - 2 months ago

Sionna Therapeutics files automatic mixed securities shelf


Sionna Therapeutics reports Q4 EPS (46c), consensus (55c)

2026-03-02T12:09:18.000Z - 2 months ago

Sionna Therapeutics reports Q4 EPS (46c), consensus (55c)


Sionna Therapeutics initiated with an Outperform at Citizens

2026-02-24T09:40:13.000Z - 2 months ago

Sionna Therapeutics initiated with an Outperform at Citizens


Sionna Therapeutics price target raised to $58 from $50 at BTIG

2026-01-07T12:10:27.000Z - 4 months ago

Sionna Therapeutics price target raised to $58 from $50 at BTIG


Sionna Therapeutics initiated with a Buy at BTIG

2025-11-18T21:21:15.000Z - 6 months ago

Sionna Therapeutics initiated with a Buy at BTIG


Sionna Therapeutics reports Q3 EPS (46c), consensus (47c)

2025-11-05T12:16:19.000Z - 6 months ago

Sionna Therapeutics reports Q3 EPS (46c), consensus (47c)


Sionna Therapeutics expects cash to fund operations into 2028

2025-11-05T12:16:12.000Z - 6 months ago

Sionna Therapeutics expects cash to fund operations into 2028


Sionna Therapeutics Transcript: Study Update

Jun 4, 2025, 8:00 AM EDT - 1 year ago

Sionna Therapeutics Transcript: Study Update


Sionna Therapeutics Prices Upsized Initial Public Offering

Feb 6, 2025, 7:51 PM EST - 1 year ago

Sionna Therapeutics Prices Upsized Initial Public Offering


laaarsas
laaarsas May. 6 at 9:33 PM
$SION What dose will we see in phase 2?
0 · Reply
laaarsas
laaarsas May. 6 at 1:12 PM
$SION Why is this stock valued as if the clinical outcome is almost certain?
0 · Reply
laaarsas
laaarsas May. 5 at 7:41 PM
$SION Stock already up much. How much could ph2a data move share price? Tell me
0 · Reply
laaarsas
laaarsas May. 5 at 7:31 PM
$SION Hi donkeys what is vibe in here?
0 · Reply
DARKP00L
DARKP00L May. 5 at 1:30 PM
$SION 09:24 on May. 05 2026 Wedbush Initiates Coverage On Sionna Therapeutics with Outperform Rating, Announces Price Target of $53 #tradeideas
1 · Reply
S_Franconi
S_Franconi Apr. 21 at 11:18 AM
$SION Very bullish. 59 watchers, April 21, 2026.
0 · Reply
Doozio
Doozio Apr. 19 at 5:22 PM
$SION appears ready on the DLO ONTO 🐒🍌🧠⏰♾️
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Mar. 19 at 11:48 AM
$SION RSI: 36.98, MACD: -0.6171 Vol: 1.45, MA20: 36.36, MA50: 38.33 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
BillionerOfKing
BillionerOfKing Feb. 22 at 2:53 PM
$SION Current Stock Price: $35.52
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 14 at 3:10 AM
$SION RSI: 36.97, MACD: -0.9642 Vol: 2.85, MA20: 40.21, MA50: 40.77 ⚪ HOLD - Sideways 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
Trainguy1
Trainguy1 Feb. 5 at 8:03 PM
$SION @S_Franconi Orbimed sold 1/3 of their SION stock, and Orbimed’s independent director sold some stock too. So the SP dropped by 20%. If Orbimed lost confidence, they would have sold out. I’m holding my shares. BTW - SION is currently testing cystic fibrosis therapeutics. They expect to have top line read outs from their SION-719 phase 2 trial and both ph1 combo therapy trials in mid 2026.
1 · Reply
CH_Expat
CH_Expat Feb. 5 at 6:50 PM
$SION Kill it! Buyer in Mid 20s!
0 · Reply
DispersionIQ
DispersionIQ Feb. 4 at 1:29 PM
$SION is a small-cap biotech developing cancer therapies; its lead candidate shows promise in early trials, but the path to approval and commercialization is long and capital-intensive.
1 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Jan. 24 at 2:00 AM
$SION RSI: 54.64, MACD: 0.0035 Vol: 2.37, MA20: 40.33, MA50: 40.76 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
BillionerOfKing
BillionerOfKing Jan. 6 at 9:54 PM
$SION Current Stock Price: $37.21
0 · Reply
DerechosDelta
DerechosDelta Dec. 26 at 2:41 PM
$SION Trading behavior shows investors weighing repeatability of results above expansion claims. Capital allocation choices will reveal true priorities. Clear execution would attract broader institutional participation. Investors will likely reward proof above promises.
1 · Reply
JarvisFlow
JarvisFlow Dec. 23 at 4:08 PM
LifeSci Capital has updated their rating for Sionna Therapeutics ( $SION ) to Outperform with a price target of 60.
1 · Reply
dogDazeSummer
dogDazeSummer Dec. 18 at 8:56 PM
$IFRX Part 2 Hidden Gems according to Guggenheim (don’t shooot messanger): “….where AMGN’s avacopan could limited therapeutic window. IFRX has recently announced positive topline results from the Phase IIa 4-week basket study: (1) In HS, Izicopan demonstrated rapid & compelling efficacy that are aligned with successful biologic comparators, with clear safety and a dose-dependent profile; (2) In CSU, while the efficacy signal is stronger in HS,‘904 drives reduction in UAS7 within a range indicative of clinical activity. Given there is no other development in the oral C5aR space, IFRX could inaugurate a new MoA across this multibillion dollar indication market. Initiation of a Phase II program for Izicopan…. Also mentioned as hidden gems: $RAPT $PHAT $SION $FBRX
1 · Reply
BillionerOfKing
BillionerOfKing Dec. 12 at 11:55 PM
$SION Current Stock Price: $42.79
0 · Reply
theflynews
theflynews Dec. 1 at 9:37 PM
What You Missed On Wall Street On Monday - $SION - https://thefly.com/permalinks/entry.php/SIONid4248109?1764624879C38
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