Market Cap 5.02B
Revenue (ttm) 434.43M
Net Income (ttm) 275.19M
EPS (ttm) N/A
PE Ratio 129.39
Forward PE 271.93
Profit Margin 63.35%
Debt to Equity Ratio 0.00
Volume 799,000
Avg Vol 928,272
Day's Range N/A - N/A
Shares Out 62.52M
Stochastic %K 28%
Beta 2.26
Analysts Strong Sell
Price Target $95.92

Company Profile

Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical trials indicated to block biological pathways targeted by marketed injectable antibody drugs; and PN-943...

Industry: Biotechnology
Sector: Healthcare
Phone: 510 474 0170
Address:
7707 Gateway Boulevard, Suite 140, Newark, United States
OfficialStocktwitsUser
OfficialStocktwitsUser Jan. 14 at 12:39 PM
$PTGX RSI: 23.76, MACD: -1.5961 Vol: 4.01, MA20: 86.09, MA50: 85.68 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
outlawinvestor1
outlawinvestor1 Jan. 13 at 4:23 PM
$PTGX icotrokinra is now ICOTIDE!
0 · Reply
Quantumup
Quantumup Jan. 13 at 12:01 PM
Guggenheim reiterated Best Idea $ABVX at Buy/$175 after hosting an investor dinner with Abivax's management yesterday. $LLY ABBV PFE $PTGX - JNJ Here's what Guggenheim said in its note: https://x.com/Quantumup1/status/2011044955871920247?s=20
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outlawinvestor1
outlawinvestor1 Jan. 13 at 4:27 AM
$PTGX JPM Healthcare Conference Day/Time: Tuesday, January 13 at 8:15 AM PST Webcast: https://jpmorgan.metameetings.net/events/healthcare26/sessions/317262-protagonist-therapeutics-inc/webcast?gpu_only=true&kiosk=true
0 · Reply
AlucardPendragon
AlucardPendragon Jan. 12 at 5:59 PM
$PTGX looks like i was wrong. Closed my position at a $1K loss
0 · Reply
AlucardPendragon
AlucardPendragon Jan. 9 at 8:29 PM
$PTGX I'm thinking they get bought out at$110 by JnJ on Monday
1 · Reply
Quantumup
Quantumup Jan. 8 at 11:45 AM
BTIG⬆️ $ABVX's PT to $150 from $120 and reiterated at a Buy after ABVX announced an updated 2026 outlook for their clinical pipeline. LLY PFE ABBV $PTGX - $JNJ Here's what BTIG had to say: https://x.com/Quantumup1/status/2009229128763953344?s=20
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Quantumup
Quantumup Jan. 8 at 11:09 AM
Leerink reiterated $ABVX Outperform/$138 LLY ABBV PFE $PTGX - $JNJ Citizens reiterated at a Market Outperform/$131 Here's what Leerink and Citizens had to say in their notes to investors: https://x.com/Quantumup1/status/2009220058770235789?s=20
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BluntForceOptions
BluntForceOptions Jan. 6 at 2:26 PM
$ALMS GM, y'all. This is why conviction matters in biotech. Congrats to everyone who stuck with this one and actually did the homework. Today’s massive move reflects the market finally responding to definitive Phase 3 validation after months of disconnect between fundamentals and price. I laid out the bull case well before this readout; this morning simply confirms it. Quick breakdown of today’s ONWARD Phase 3 data: Key Phase 3 takeaways (ONWARD1 & ONWARD2): Both trials met all primary and secondary endpoints with high statistical significance ~74% PASI-75 and ~59% sPGA 0/1 by Week 16 By Week 24, responses deepened meaningfully: ~65% PASI-90 40% PASI-100 Rapid onset, with separation from placebo on PASI-90 as early as Week 4 Outperformed apremilast across all PASI endpoints (p < 0.0001) Safety and tolerability were clean and consistent with Phase 2 -- no new signals Co plans to submit an NDA in 2H 2026 What matters here is where this lands competitively. External commentary today framed envudeucitinib as competitive with -- and in some measures rivaling -- other late-stage oral psoriasis programs from $JNJ / $PTGX and $TAK Takeda. That’s the real benchmark -- and ALMS just put itself squarely in that conversation. This is the payoff when a late-stage biotech delivers on Phase 3 execution: strong efficacy, durability, competitive differentiation, and a clean safety profile -- delivered at scale across two global Phase 3 trials. Giddy up.
1 · Reply
StockOrTwist
StockOrTwist Dec. 26 at 7:17 AM
$PTGX https://www.youtube.com/watch?v=MDMcQlTdDUQ
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Latest News on PTGX
RTW Investments' Rod Wong: Expect more deals in biotech space

Oct 10, 2025, 1:21 PM EDT - 3 months ago

RTW Investments' Rod Wong: Expect more deals in biotech space

JNJ XBI


Johnson & Johnson in Talks to Buy Protagonist Therapeutics

Oct 10, 2025, 11:13 AM EDT - 3 months ago

Johnson & Johnson in Talks to Buy Protagonist Therapeutics

JNJ


Protagonist Therapeutics Reports Granting of Inducement Award

Apr 16, 2025, 4:05 PM EDT - 9 months ago

Protagonist Therapeutics Reports Granting of Inducement Award


Overlooked Stock: PTGX

Mar 10, 2025, 4:57 PM EDT - 11 months ago

Overlooked Stock: PTGX


Why Is Protagonist Therapeutics Stock Trading Higher On Monday?

Mar 10, 2025, 10:04 AM EDT - 11 months ago

Why Is Protagonist Therapeutics Stock Trading Higher On Monday?


OfficialStocktwitsUser
OfficialStocktwitsUser Jan. 14 at 12:39 PM
$PTGX RSI: 23.76, MACD: -1.5961 Vol: 4.01, MA20: 86.09, MA50: 85.68 🟢 BUY - Uptrend + healthy RSI 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
outlawinvestor1
outlawinvestor1 Jan. 13 at 4:23 PM
$PTGX icotrokinra is now ICOTIDE!
0 · Reply
Quantumup
Quantumup Jan. 13 at 12:01 PM
Guggenheim reiterated Best Idea $ABVX at Buy/$175 after hosting an investor dinner with Abivax's management yesterday. $LLY ABBV PFE $PTGX - JNJ Here's what Guggenheim said in its note: https://x.com/Quantumup1/status/2011044955871920247?s=20
0 · Reply
outlawinvestor1
outlawinvestor1 Jan. 13 at 4:27 AM
$PTGX JPM Healthcare Conference Day/Time: Tuesday, January 13 at 8:15 AM PST Webcast: https://jpmorgan.metameetings.net/events/healthcare26/sessions/317262-protagonist-therapeutics-inc/webcast?gpu_only=true&kiosk=true
0 · Reply
AlucardPendragon
AlucardPendragon Jan. 12 at 5:59 PM
$PTGX looks like i was wrong. Closed my position at a $1K loss
0 · Reply
AlucardPendragon
AlucardPendragon Jan. 9 at 8:29 PM
$PTGX I'm thinking they get bought out at$110 by JnJ on Monday
1 · Reply
Quantumup
Quantumup Jan. 8 at 11:45 AM
BTIG⬆️ $ABVX's PT to $150 from $120 and reiterated at a Buy after ABVX announced an updated 2026 outlook for their clinical pipeline. LLY PFE ABBV $PTGX - $JNJ Here's what BTIG had to say: https://x.com/Quantumup1/status/2009229128763953344?s=20
0 · Reply
Quantumup
Quantumup Jan. 8 at 11:09 AM
Leerink reiterated $ABVX Outperform/$138 LLY ABBV PFE $PTGX - $JNJ Citizens reiterated at a Market Outperform/$131 Here's what Leerink and Citizens had to say in their notes to investors: https://x.com/Quantumup1/status/2009220058770235789?s=20
0 · Reply
BluntForceOptions
BluntForceOptions Jan. 6 at 2:26 PM
$ALMS GM, y'all. This is why conviction matters in biotech. Congrats to everyone who stuck with this one and actually did the homework. Today’s massive move reflects the market finally responding to definitive Phase 3 validation after months of disconnect between fundamentals and price. I laid out the bull case well before this readout; this morning simply confirms it. Quick breakdown of today’s ONWARD Phase 3 data: Key Phase 3 takeaways (ONWARD1 & ONWARD2): Both trials met all primary and secondary endpoints with high statistical significance ~74% PASI-75 and ~59% sPGA 0/1 by Week 16 By Week 24, responses deepened meaningfully: ~65% PASI-90 40% PASI-100 Rapid onset, with separation from placebo on PASI-90 as early as Week 4 Outperformed apremilast across all PASI endpoints (p < 0.0001) Safety and tolerability were clean and consistent with Phase 2 -- no new signals Co plans to submit an NDA in 2H 2026 What matters here is where this lands competitively. External commentary today framed envudeucitinib as competitive with -- and in some measures rivaling -- other late-stage oral psoriasis programs from $JNJ / $PTGX and $TAK Takeda. That’s the real benchmark -- and ALMS just put itself squarely in that conversation. This is the payoff when a late-stage biotech delivers on Phase 3 execution: strong efficacy, durability, competitive differentiation, and a clean safety profile -- delivered at scale across two global Phase 3 trials. Giddy up.
1 · Reply
StockOrTwist
StockOrTwist Dec. 26 at 7:17 AM
$PTGX https://www.youtube.com/watch?v=MDMcQlTdDUQ
0 · Reply
WallStreetBuyDip
WallStreetBuyDip Dec. 25 at 8:10 PM
$PTGX Trading at $88.84, with a high of $95.35 and a low of $35.09. Average volume stands at 995,142, recent volume around 154,100 to 2,227,500.
0 · Reply
StockOrTwist
StockOrTwist Dec. 25 at 7:41 PM
$PTGX https://youtu.be/MDMcQlTdDUQ
0 · Reply
WallStreetBuyDip
WallStreetBuyDip Dec. 25 at 7:33 PM
Comparing trending tickers $CIGI vs $PTGX: CIGI has risen slightly by 0.60% to $149.91 with a trading volume of 29.4K, which is below its average of 129.2K. PTGX, on the other hand, has a smaller gain of 0.12%, reaching $88.84, but with a higher trading volume of 154.1K, significantly above its usual 995.1K. CIGI's price increase isn't matched by volume, while PTGX, despite its modest price change, is seeing much heavier trading activity.
0 · Reply
WallStreetBuyDip
WallStreetBuyDip Dec. 25 at 6:34 PM
Comparing trending tickers $PTGX vs $CIGI: $PTGX Massive volume spikes recently compared to the average volume. Price has been moving between $85.79 and $88.84. Highest at $95.35 and lowest at $35.09. With such high volume, waiting for the H% to cool down before considering a position. Meanwhile, $CIGI Massive volume decrease today compared to the average volume of 129,157 shares. Price holding steady at $149.91 with recent volatility. Smart move might be to wait for a lower H% before considering an entry.
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WallStreetBuyDip
WallStreetBuyDip Dec. 25 at 6:25 PM
my rules are simple for $PTGX - wait for H% to get low then buy
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biochirp
biochirp Dec. 22 at 4:25 PM
$ABVX J&J losing here means they’re forced to pickup $PTGX
0 · Reply
Quantumup
Quantumup Dec. 22 at 11:32 AM
a/o Friday: BMO Capital reiterated $IRON Outperform/$120 Jefferies reiterated Buy/$154 TD Cowen reiterated Buy Stifel analyst reiterated Buy/$125 $CLVLY Mitsubishi Tanabe Pharma $NVS ABBV GERN $PTGX - $TAK Here's what the Analysts had to say on Friday:
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Sw1ngb0t
Sw1ngb0t Dec. 19 at 10:21 PM
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justiceforb_85
justiceforb_85 Dec. 17 at 8:11 PM
$PTGX re-entered. Look forward to rusfertide approval, further development of icotrokinra, and advancement of PN-881 (oral IL-17 antagonist).
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JarvisFlow
JarvisFlow Dec. 17 at 5:54 PM
Barclays updates rating for Protagonist Therapeutics ( $PTGX ) to Overweight, target set at 88 → 108.
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Sw1ngb0t
Sw1ngb0t Dec. 13 at 9:22 PM
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blueb22
blueb22 Dec. 12 at 7:57 PM
$PTGX - J&J BO should come out next week, otherwise it would be during JPM conference week. They have to buy it now. Other short term catalyst would be BLA filling for PV drug (reta) - PR could come today or by next Friday.
0 · Reply