Market Cap 7.18B
Revenue (ttm) 0.00
Net Income (ttm) -425.38M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 716,000
Avg Vol 687,564
Day's Range N/A - N/A
Shares Out 79.00M
Stochastic %K 9%
Beta 1.15
Analysts Strong Sell
Price Target $143.84

Company Profile

Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are Zidesamtinib (NVL-520), a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung ca...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 357 7000
Address:
One Broadway, 14th Floor, Cambridge, United States
Hognose
Hognose Jun. 4 at 5:07 AM
$ABVX $NUVL $PRAX all having bad news on the same day? Or just over reacting to any data right now?
0 · Reply
JustShutupAndBuy
JustShutupAndBuy Jun. 3 at 7:51 PM
$NUVL somebody knows something…
1 · Reply
ConsulHorkos
ConsulHorkos Jun. 3 at 4:38 PM
$NUVB $NUVL Just my thoughts/summary not investment advice. Outlined that growth for Ibtrozi is as expected and increased testing and awareness may lead to faster adoption. NCCN guidelines do not allow for IO only treatment which is excellent for Ibtrozi. The importance of testing is become more apparent and being adopted in other rare cancers, so it will spill over to NSCLC. Ibtrozi improves the cognitive function of patients. ASCO data continues to show why Ibrtozi is best in class. NUVL trial given its lack of real world population could be rejected. New trials for Safu and the DDC program will be announced this year. The Safu study will be designed to see if Safu provides a response to patients that have tried and failed vora. With around 1000 patients not responding on Vora this year alone that in itself is a large patient population. The study may enroll 50-80 patients and if it establishes a response rate above 20% the company may ask for early approval.
3 · Reply
ConsulHorkos
ConsulHorkos Jun. 3 at 4:22 PM
$NUVB Part 3 Competition to Ibtrozi $NUVL "And if you look and look at what patients will seek in a in a drug, by far the most important thing to patients is how long will I respond to the drug? I'm getting. So we think that until someone has a duration of response better than it. 50 months can be really hard to displace Ibrtozi in the ros1 space." Hung "Nuvalent did show some activity in the third line setting, and just to refresh your memories, the FDA actually gave it a breakthrough designation for Ibtrozi both the first and second line setting and gave Nuvalent breakthrough designation in the third line setting. And also ibtrozi was granted priority review in our FDA cycle. And Nuvalent was granted standard review." Hung Ibtrozi Trek B Inhibition - Our amount of trek B inhibition has not caused any issues with tolerability. We believe that the 50 month duration of response that we're seeing with them could very well be in part due to the amount of Trek B inhibition that we have.
0 · Reply
Belisimo
Belisimo Jun. 3 at 1:10 PM
$NUVL Why does ST post these quotes that are way off???
0 · Reply
ClassiTrader
ClassiTrader Jun. 2 at 4:48 PM
$NUVL 🤔
0 · Reply
IN0V8
IN0V8 Jun. 2 at 2:08 PM
$NUVL Adding
0 · Reply
IN0V8
IN0V8 Jun. 2 at 1:47 PM
$NUVL Bought at $92.50
0 · Reply
Arcides
Arcides Jun. 1 at 6:31 PM
$NUVL a lot of volume dump, no news...
3 · Reply
TKkamen
TKkamen Jun. 1 at 2:36 PM
$NUVL what’s going on?
2 · Reply
Latest News on NUVL
Nuvalent Slides: Corporate presentation

May 27, 2026, 8:00 AM EDT - 10 days ago

Nuvalent Slides: Corporate presentation


Nuvalent initiated with an Outperform at Bernstein

2026-05-21T20:28:23.000Z - 16 days ago

Nuvalent initiated with an Outperform at Bernstein


Nuvalent reports Q1 EPS ($1.39), consensus ($1.31)

2026-05-07T11:04:05.000Z - 4 weeks ago

Nuvalent reports Q1 EPS ($1.39), consensus ($1.31)


Nuvalent Earnings release: Q1 2026

May 7, 2026, 6:30 AM EDT - 4 weeks ago

Nuvalent Earnings release: Q1 2026


Nuvalent Quarterly report: Q1 2026

May 7, 2026, 6:30 AM EDT - 4 weeks ago

Nuvalent Quarterly report: Q1 2026


Nuvalent Proxy statement: Proxy filing

Apr 28, 2026, 8:00 AM EDT - 5 weeks ago

Nuvalent Proxy statement: Proxy filing


Nuvalent Proxy statement: Proxy filing

Apr 28, 2026, 8:00 AM EDT - 5 weeks ago

Nuvalent Proxy statement: Proxy filing


Nuvalent Slides: Corporate presentation

Apr 8, 2026, 7:00 AM EDT - 2 months ago

Nuvalent Slides: Corporate presentation


Nuvalent submits neladalkib NDA to FDA

2026-04-07T10:47:34.000Z - 2 months ago

Nuvalent submits neladalkib NDA to FDA


Nuvalent initiated with an Overweight at Wells Fargo

2026-03-30T09:30:09.000Z - 2 months ago

Nuvalent initiated with an Overweight at Wells Fargo


Nuvalent Transcript: Leerink Global Healthcare Conference 2026

Mar 9, 2026, 2:20 PM EDT - 3 months ago

Nuvalent Transcript: Leerink Global Healthcare Conference 2026


Nuvalent price target raised to $138 from $132 at UBS

2026-03-02T14:12:04.000Z - 3 months ago

Nuvalent price target raised to $138 from $132 at UBS


Nuvalent Earnings release: Q4 2025

Feb 26, 2026, 7:00 AM EST - 3 months ago

Nuvalent Earnings release: Q4 2025


Nuvalent Annual report: Q4 2025

Feb 26, 2026, 7:00 AM EST - 3 months ago

Nuvalent Annual report: Q4 2025


Nuvalent Slides: Corporate presentation

Feb 26, 2026, 7:00 AM EST - 3 months ago

Nuvalent Slides: Corporate presentation


Nuvalent reports Q4 EPS ($1.58), consensus ($1.44)

2026-02-26T11:51:23.000Z - 3 months ago

Nuvalent reports Q4 EPS ($1.58), consensus ($1.44)


Nuvalent Transcript: 44th Annual J.P. Morgan Healthcare Conference

Jan 13, 2026, 12:00 PM EST - 5 months ago

Nuvalent Transcript: 44th Annual J.P. Morgan Healthcare Conference


Nuvalent Slides: Company presentation

Jan 12, 2026, 7:00 AM EST - 5 months ago

Nuvalent Slides: Company presentation


Nuvalent files automatic mixed securities shelf

2025-12-22T12:55:23.000Z - 5 months ago

Nuvalent files automatic mixed securities shelf


Nuvalent price target lowered to $145 from $147 at JPMorgan

2025-12-19T12:01:02.000Z - 6 months ago

Nuvalent price target lowered to $145 from $147 at JPMorgan


Nuvalent Appoints Ron Squarer to Board of Directors

Dec 10, 2025, 4:01 PM EST - 6 months ago

Nuvalent Appoints Ron Squarer to Board of Directors


Nuvalent initiated with a Buy at Truist

2025-11-24T12:31:03.000Z - 6 months ago

Nuvalent initiated with a Buy at Truist


Nuvalent 4.95M share Secondary priced at $101.00

2025-11-19T11:15:20.000Z - 7 months ago

Nuvalent 4.95M share Secondary priced at $101.00


Nuvalent Announces Pricing of Public Offering of Common Stock

Nov 18, 2025, 11:50 PM EST - 7 months ago

Nuvalent Announces Pricing of Public Offering of Common Stock


Nuvalent price target raised to $135 from $120 at Goldman Sachs

2025-11-18T14:31:34.000Z - 7 months ago

Nuvalent price target raised to $135 from $120 at Goldman Sachs


Nuvalent price target raised to $155 from $125 at Guggenheim

2025-11-18T12:21:05.000Z - 7 months ago

Nuvalent price target raised to $155 from $125 at Guggenheim


Nuvalent Announces Public Offering of Common Stock

Nov 17, 2025, 4:01 PM EST - 7 months ago

Nuvalent Announces Public Offering of Common Stock


Nuvalent Transcript: Study Update

Nov 17, 2025, 8:00 AM EST - 7 months ago

Nuvalent Transcript: Study Update


Nuvalent Press release: Study Update

Nov 17, 2025, 8:00 AM EST - 7 months ago

Nuvalent Press release: Study Update


Nuvalent Slides: Study Update

Nov 17, 2025, 8:00 AM EST - 7 months ago

Nuvalent Slides: Study Update


Nuvalent Slides: Corporate Presentation

Oct 30, 2025, 8:00 AM EDT - 7 months ago

Nuvalent Slides: Corporate Presentation


Nuvalent Quarterly report: Q3 2025

Oct 30, 2025, 6:30 AM EDT - 7 months ago

Nuvalent Quarterly report: Q3 2025


Nuvalent Earnings release: Q3 2025

Oct 30, 2025, 6:30 AM EDT - 7 months ago

Nuvalent Earnings release: Q3 2025


Nuvalent Transcript: UBS Virtual Oncology Day

Oct 1, 2025, 3:30 PM EDT - 8 months ago

Nuvalent Transcript: UBS Virtual Oncology Day


Nuvalent to Participate in the UBS 2025 Virtual Oncology Day

Sep 24, 2025, 6:30 AM EDT - 9 months ago

Nuvalent to Participate in the UBS 2025 Virtual Oncology Day


Nuvalent Transcript: Cantor Global Healthcare Conference 2025

Sep 4, 2025, 9:45 AM EDT - 9 months ago

Nuvalent Transcript: Cantor Global Healthcare Conference 2025


Nuvalent Quarterly report: Q2 2025

Aug 7, 2025, 6:30 AM EDT - 10 months ago

Nuvalent Quarterly report: Q2 2025


Nuvalent Earnings release: Q2 2025

Aug 7, 2025, 6:30 AM EDT - 10 months ago

Nuvalent Earnings release: Q2 2025


Nuvalent Transcript: Investor Update

Jun 24, 2025, 8:00 AM EDT - 1 year ago

Nuvalent Transcript: Investor Update


Nuvalent Press release: Investor Update

Jun 24, 2025, 8:00 AM EDT - 1 year ago

Nuvalent Press release: Investor Update


Nuvalent Slides: Investor Update

Jun 24, 2025, 8:00 AM EDT - 1 year ago

Nuvalent Slides: Investor Update


Nuvalent Appoints Christy Oliger to Board of Directors

Jun 18, 2025, 4:30 PM EDT - 1 year ago

Nuvalent Appoints Christy Oliger to Board of Directors


Nuvalent Earnings release: Q1 2025

May 7, 2025, 6:00 PM EDT - 1 year ago

Nuvalent Earnings release: Q1 2025


Nuvalent Quarterly report: Q1 2025

May 7, 2025, 6:00 PM EDT - 1 year ago

Nuvalent Quarterly report: Q1 2025


Nuvalent Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Nuvalent Proxy statement: Proxy Filing


Nuvalent Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Nuvalent Proxy statement: Proxy Filing


Nuvalent Earnings release: Q4 2024

Feb 27, 2025, 7:00 AM EST - 1 year ago

Nuvalent Earnings release: Q4 2024


Nuvalent Annual report: Q4 2024

Feb 27, 2025, 7:00 AM EST - 1 year ago

Nuvalent Annual report: Q4 2024


Nuvalent Appoints Grant Bogle to Board of Directors

Dec 9, 2024, 6:30 AM EST - 1 year ago

Nuvalent Appoints Grant Bogle to Board of Directors


Nuvalent Transcript: Stifel 2024 Healthcare Conference

Nov 19, 2024, 3:35 PM EST - 1 year ago

Nuvalent Transcript: Stifel 2024 Healthcare Conference


Nuvalent Earnings release: Q3 2024

Nov 12, 2024, 7:00 AM EST - 1 year ago

Nuvalent Earnings release: Q3 2024


Nuvalent Quarterly report: Q3 2024

Nov 12, 2024, 7:00 AM EST - 1 year ago

Nuvalent Quarterly report: Q3 2024


Cancer Biotech Nuvalent's Stock Jumps on Positive Data

Sep 16, 2024, 11:18 AM EDT - 1 year ago

Cancer Biotech Nuvalent's Stock Jumps on Positive Data


Hognose
Hognose Jun. 4 at 5:07 AM
$ABVX $NUVL $PRAX all having bad news on the same day? Or just over reacting to any data right now?
0 · Reply
JustShutupAndBuy
JustShutupAndBuy Jun. 3 at 7:51 PM
$NUVL somebody knows something…
1 · Reply
ConsulHorkos
ConsulHorkos Jun. 3 at 4:38 PM
$NUVB $NUVL Just my thoughts/summary not investment advice. Outlined that growth for Ibtrozi is as expected and increased testing and awareness may lead to faster adoption. NCCN guidelines do not allow for IO only treatment which is excellent for Ibtrozi. The importance of testing is become more apparent and being adopted in other rare cancers, so it will spill over to NSCLC. Ibtrozi improves the cognitive function of patients. ASCO data continues to show why Ibrtozi is best in class. NUVL trial given its lack of real world population could be rejected. New trials for Safu and the DDC program will be announced this year. The Safu study will be designed to see if Safu provides a response to patients that have tried and failed vora. With around 1000 patients not responding on Vora this year alone that in itself is a large patient population. The study may enroll 50-80 patients and if it establishes a response rate above 20% the company may ask for early approval.
3 · Reply
ConsulHorkos
ConsulHorkos Jun. 3 at 4:22 PM
$NUVB Part 3 Competition to Ibtrozi $NUVL "And if you look and look at what patients will seek in a in a drug, by far the most important thing to patients is how long will I respond to the drug? I'm getting. So we think that until someone has a duration of response better than it. 50 months can be really hard to displace Ibrtozi in the ros1 space." Hung "Nuvalent did show some activity in the third line setting, and just to refresh your memories, the FDA actually gave it a breakthrough designation for Ibtrozi both the first and second line setting and gave Nuvalent breakthrough designation in the third line setting. And also ibtrozi was granted priority review in our FDA cycle. And Nuvalent was granted standard review." Hung Ibtrozi Trek B Inhibition - Our amount of trek B inhibition has not caused any issues with tolerability. We believe that the 50 month duration of response that we're seeing with them could very well be in part due to the amount of Trek B inhibition that we have.
0 · Reply
Belisimo
Belisimo Jun. 3 at 1:10 PM
$NUVL Why does ST post these quotes that are way off???
0 · Reply
ClassiTrader
ClassiTrader Jun. 2 at 4:48 PM
$NUVL 🤔
0 · Reply
IN0V8
IN0V8 Jun. 2 at 2:08 PM
$NUVL Adding
0 · Reply
IN0V8
IN0V8 Jun. 2 at 1:47 PM
$NUVL Bought at $92.50
0 · Reply
Arcides
Arcides Jun. 1 at 6:31 PM
$NUVL a lot of volume dump, no news...
3 · Reply
TKkamen
TKkamen Jun. 1 at 2:36 PM
$NUVL what’s going on?
2 · Reply
Merlintrader
Merlintrader May. 25 at 5:39 PM
$NUVL Three Near-Term Biotech Catalysts To Watch: Nuvalent, Legend Biotech and Zenas BioPharma $NUVL $LEGN $ZBIO https://www.merlintrader.com/three-biotech-catalysts-nuvl-legn-zbio/
1 · Reply
Quantumup
Quantumup May. 22 at 10:23 AM
Bernstein Societe Generale🏁 $NUVL Outperform; $189 and said: Nuvalent is our best idea and top pick for investors. $AZN BMY RHHBY PFE $NUVB Here's what Bernstein Societe Generale went on to say in its initiation report: https://x.com/Quantumup1/status/2057768732068384884?s=20
0 · Reply
justiceforb_85
justiceforb_85 May. 22 at 12:40 AM
$NUVL very impressive updates on neladalkib and zidesamtinib, the latter in ROS1 malignancies aside from NSCLC.
0 · Reply
BioRich
BioRich May. 20 at 7:07 AM
$AVXL $NUVL $GPCR $OPTT $PRTA (Sorry, Placeholders) Cheers!
1 · Reply
Quantumup
Quantumup May. 5 at 10:35 AM
Citizens reiterated $NUVB Market Outperform; $10, and said: The Ibtrozi launch is progressing in the right direction, with an increasing share of new prescriptions coming from the front-line ROS1+ NSCLC population. $BMY $NUVL PFE RHHBY Citizens added—Over the past three quarters, front-line new patients starts have increased, from 30% to over 50% of Ibtrozi scripts. Based on updated pivotal TRUST-I/II data shared at AACR (our coverage here), with the median duration of response maturing to nearly 50 months, Ibtrozi has increased revenue-generating potential based on revenue stacking. Management noted that revenue-stacking effects were first seen in 1Q26, and as more new starts come from front-line patients this should continue to increase quarter over quarter. Management remains comfortable with the YE26 consensus. We highlight the name, especially given the sell-off after the 4Q25 earnings report, as we are now seeing progress with the launch.
0 · Reply
forprofit12
forprofit12 May. 1 at 4:18 PM
$NUVL added. Will add more if it falls
0 · Reply
jayessbee
jayessbee Apr. 30 at 12:28 PM
$NUVL https://www.businesswire.com/news/home/20260430014027/en/Guardant-Health-Announces-Multi-Year-Strategic-Collaboration-with-Nuvalent-to-Develop-Companion-Diagnostics-and-Support-Potential-Commercialization-of-Targeted-Cancer-Therapies-Using-the-Guardant-Infinity-Platform
0 · Reply
Quantumup
Quantumup Apr. 28 at 12:33 PM
H.C. Wainwright reiterated $NUVB Buy; $17, and said: Yesterday, Nuvation announced that IBTROZI (taletrectinib) was added to the National Comprehensive Cancer Network (NCCN) Guidelines for CNS Cancers. $BMY $NUVL PFE RHHBY H.C. Wainwright added—Per the updated guidelines, the NCCN now recommends taletrectinib as a systemic therapy option for ROS1+ NSCLC patients with brain metastases. This recommendation is supported by pooled results from the TRUST-I and TRUST-II trials. In particular, we draw investor attention to the fact that treatment with IBTROZI demonstrated 76.5% and 65.6% intracranial ORRs in TKI-naive and TKI-pretreated patients, respectively. From our perspective, this development is incrementally positive for Nuvation and should provide another tailwind for IBTROZI adoption. Accordingly, we reiterate our Buy rating and 12-month price target of $17 per share.
1 · Reply
Hognose
Hognose Apr. 28 at 8:51 AM
$CAPR $NUVL $ASND $RYTM $ABVX monsters in the making.
0 · Reply
Hognose
Hognose Apr. 24 at 6:24 AM
$NUVL big buy here.
0 · Reply
SuperGreenToday
SuperGreenToday Apr. 21 at 6:50 PM
$NUVL Share Price: $106.65 Contract Selected: Oct 16, 2026 $115 Calls Buy Zone: $7.22 – $8.93 Target Zone: $11.97 – $14.63 Potential Upside: 57% ROI Time to Expiration: 177 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Coastalcool
Coastalcool Apr. 20 at 10:05 PM
$IOVA I am still a holder here but wondering why the Market is treating $NUVL as the only winner in NSCLC, despite its $8.5 B valuation. Do smart money think $ iova will end up like $REPL re NSCLC ?