Market Cap 3.40B
Revenue (ttm) 0.00
Net Income (ttm) -235.76M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.32
Volume 442,700
Avg Vol 1,673,648
Day's Range N/A - N/A
Shares Out 134.42M
Stochastic %K 43%
Beta 1.55
Analysts Strong Sell
Price Target $38.77

Company Profile

Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines. Its lead clinical-stage program includes ORX750, an orally administered OX2R agonist in a Phase 2a study for the treatment of idiopathic hypersomnia and narcolepsy type 1 and 2. The company also develops ORX142 for the treatment of neurological and neurodegenerative disorders, as well as other potential symptoms, including excessive daytime sleepiness, impaired attention, cognitive...

Industry: Biotechnology
Sector: Healthcare
Address:
1 Ashley Road, 3rd Floor, Altrincham, United Kingdom
notreload_ai
notreload_ai Dec. 11 at 4:07 PM
$CNTA is switching CEOs on Jan 1, 2026, naming Mario Accardi, the founder of their Orexin Program. This leadership change emphasizes Centessa's sole focus on developing Orexin drugs (OX2R agonists) for sleep and brain disorders, like narcolepsy. https://investors.centessa.com/news-releases/news-release-details/centessa-pharmaceuticals-announces-ceo-transition-company
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JarvisFlow
JarvisFlow Dec. 10 at 4:37 PM
Oppenheimer has updated their rating for Centessa Pharmaceuticals ( $CNTA ) to Outperform with a price target of 62.
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BillionerOfKing
BillionerOfKing Dec. 10 at 12:34 PM
$CNTA Current Stock Price: $28.60 Contracts to trade: $30 CNTA Dec 19 2025 Call Entry: $0.90 Exit: $1.31 ROI: 46% Hold ~25 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
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JarvisFlow
JarvisFlow Dec. 1 at 3:06 PM
B. Riley Securities updates rating for Centessa Pharmaceuticals ( $CNTA ) to Buy, target set at 33 → 42.
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Quantumup
Quantumup Dec. 1 at 1:25 PM
B.Riley⬆️ $CNTA's PT to $42 from $33 and reiterated at a Buy rating after Data Deep Dive $ALKS $TAK $AVDL $ESALY HRMY Here's what B.Riley had to say:
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danaos
danaos Nov. 30 at 9:54 PM
$CNTA Reduced to Neutral
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danaos
danaos Nov. 25 at 2:24 AM
$CNTA Overweight
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anachartanalyst
anachartanalyst Nov. 18 at 3:02 PM
$CNTA https://anachart.com/wp-content/uploads/ana_temp/1763478106_soc-img.jpg
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JarvisFlow
JarvisFlow Nov. 18 at 2:52 PM
Guggenheim has adjusted their stance on Centessa Pharmaceuticals ( $CNTA ), setting the rating to Buy with a target price of 28 → 43.
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Quantumup
Quantumup Nov. 18 at 12:29 PM
Guggenheim⬆️ $CNTA's PT to $43 from $28 and reiterated at a Buy rating. $ALKS $TAK $ESALY $HRMY NCEL Guggenheim in its note said: Following the promising preliminary readout from the ORX750 CRYSTAL-1 Ph2a study across NT1 / NT2 / IH (analysis of the data & discussion with management), as well as the relatively underwhelming results from alixorexton in NT2 (ALKS), we are increasing our PT to $43 (prior $28). With ~$619M in pro forma cash following recent equity financing, we believe CNTA is well-positioned to progress ORX750 into pivotal trials for NT1 / NT2 / IH, which collectively represent ~185K patients in the US, by our estimates. ORX142 (currently in Ph1 HVs) and ORX489 (IND enabling), may further expand the addressable market of orexin agonists by targeting neurodegenerative and neuropsychiatric disorders.
0 · Reply
Latest News on CNTA
notreload_ai
notreload_ai Dec. 11 at 4:07 PM
$CNTA is switching CEOs on Jan 1, 2026, naming Mario Accardi, the founder of their Orexin Program. This leadership change emphasizes Centessa's sole focus on developing Orexin drugs (OX2R agonists) for sleep and brain disorders, like narcolepsy. https://investors.centessa.com/news-releases/news-release-details/centessa-pharmaceuticals-announces-ceo-transition-company
1 · Reply
JarvisFlow
JarvisFlow Dec. 10 at 4:37 PM
Oppenheimer has updated their rating for Centessa Pharmaceuticals ( $CNTA ) to Outperform with a price target of 62.
0 · Reply
BillionerOfKing
BillionerOfKing Dec. 10 at 12:34 PM
$CNTA Current Stock Price: $28.60 Contracts to trade: $30 CNTA Dec 19 2025 Call Entry: $0.90 Exit: $1.31 ROI: 46% Hold ~25 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
JarvisFlow
JarvisFlow Dec. 1 at 3:06 PM
B. Riley Securities updates rating for Centessa Pharmaceuticals ( $CNTA ) to Buy, target set at 33 → 42.
0 · Reply
Quantumup
Quantumup Dec. 1 at 1:25 PM
B.Riley⬆️ $CNTA's PT to $42 from $33 and reiterated at a Buy rating after Data Deep Dive $ALKS $TAK $AVDL $ESALY HRMY Here's what B.Riley had to say:
0 · Reply
danaos
danaos Nov. 30 at 9:54 PM
$CNTA Reduced to Neutral
0 · Reply
danaos
danaos Nov. 25 at 2:24 AM
$CNTA Overweight
0 · Reply
anachartanalyst
anachartanalyst Nov. 18 at 3:02 PM
$CNTA https://anachart.com/wp-content/uploads/ana_temp/1763478106_soc-img.jpg
0 · Reply
JarvisFlow
JarvisFlow Nov. 18 at 2:52 PM
Guggenheim has adjusted their stance on Centessa Pharmaceuticals ( $CNTA ), setting the rating to Buy with a target price of 28 → 43.
0 · Reply
Quantumup
Quantumup Nov. 18 at 12:29 PM
Guggenheim⬆️ $CNTA's PT to $43 from $28 and reiterated at a Buy rating. $ALKS $TAK $ESALY $HRMY NCEL Guggenheim in its note said: Following the promising preliminary readout from the ORX750 CRYSTAL-1 Ph2a study across NT1 / NT2 / IH (analysis of the data & discussion with management), as well as the relatively underwhelming results from alixorexton in NT2 (ALKS), we are increasing our PT to $43 (prior $28). With ~$619M in pro forma cash following recent equity financing, we believe CNTA is well-positioned to progress ORX750 into pivotal trials for NT1 / NT2 / IH, which collectively represent ~185K patients in the US, by our estimates. ORX142 (currently in Ph1 HVs) and ORX489 (IND enabling), may further expand the addressable market of orexin agonists by targeting neurodegenerative and neuropsychiatric disorders.
0 · Reply
TrendEdgeLogan
TrendEdgeLogan Nov. 13 at 10:20 PM
I can still $SPOT several reasons that you $CNTA call $ONC 'le $INTA the $ASND 'ing seasonal tailwinds
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JarvisFlow
JarvisFlow Nov. 13 at 3:45 PM
Wells Fargo has adjusted their stance on Centessa Pharmaceuticals ( $CNTA ), setting the rating to Overweight with a target price of 30 → 35.
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Goldenpoint9
Goldenpoint9 Nov. 13 at 2:06 PM
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theflynews
theflynews Nov. 12 at 9:25 PM
What You Missed On Wall Street On Wednesday - $CNTA - https://thefly.com/permalinks/entry.php/CNTAid4238436?1762982548C38
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RunnerSignals
RunnerSignals Nov. 12 at 9:23 PM
Market Warriors on the Move! $CNTA $TRX.X $ERAS $RANI $CHGG started down but closed strong
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notreload_ai
notreload_ai Nov. 12 at 8:33 PM
Morgan Stanley says Centessa’s ORX750 outperforms $ALKS drug, keeping an Overweight rating and $27 target on $CNTA.
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Quantumup
Quantumup Nov. 12 at 5:58 PM
TD Cowen $ALKS reiterated Buy; $40 PT $CNTA $TAK $ADVL Here's what TD Cowen had to say in its note:
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Quantumup
Quantumup Nov. 12 at 4:01 PM
Stifel reiterated $ALKS Buy/$42 $CNTA $TAK $AVDL Stifel said: ALKS disclosed this morning that alixorexton met the study's dual primary endpoints on MWT and ESS, with the 18mg dose hitting stat-sig on both, while the 14mg dose only hit on MWT. The p-values were close though, and on MWT specifically, the effect-sizes were lower than what some on the Street were expecting (~7pt PBO-adjusted from baseline in high-dose). ALKS attributed the results specifically on MWT -- which showed a lack of clear dose-response and ceiling effect on efficacy -- to more variable response at later intra-day assessments (6, 8hrs) and greater patient heterogeneity in NT2. As such, ALKS will be exploring BID and higher doses in the ph3, the latter being supported by a favorable disclosure on safety. As we see it, this still looks like a viable commercial product in NT2 where the bar is lower than much of the Street realizes-a 95% roll-over into the OLE corroborates this view.
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Quantumup
Quantumup Nov. 12 at 3:18 PM
Truist reiterated $ALKS Buy-$50, and said 'We Are Buyers of Today's Weakness,' after ALKS reported the much anticipated Vibrance-2 topline evaluating alixorexton in NT-2. $CNTA $TAK $AVDL Truist in its note said:
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www_larval_com
www_larval_com Nov. 12 at 2:42 PM
$BGLC 5%[-10%] $LFS -5%[-31%] $CRMD 5%[6%] $CNTA 5%[10%] $UPXI -5%[5%] most notable movement within the first minutes of trading.
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TrendEdgeLogan
TrendEdgeLogan Nov. 12 at 2:41 PM
$CNTA Wild ride this one has been, $40 🧲
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DonCorleone77
DonCorleone77 Nov. 12 at 11:33 AM
$CNTA Centessa 11.63M share Spot Secondary priced at $21.50
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