JFais
Oct 31, 11:26 AM
$OBX (NP)
Interesting SITC abstract coming up:
OBX-115 TIL cell therapy in ICI-resistant advanced melanoma: Pooled safety and updated efficacy with minimally invasive tumor tissue procurement, low-dose lymphodepletion, and IL2-free regimen
Slides compare 67% ORR in median 2 prior lines of therapy vs 31% for
$IOVA Amtagvi pivotal trial (not a fair comparison though, as real-world data in 2 or fewer prior lines yielded 52% ORR)
Favorable safety, no DLTs, treatment-related mortality or ICU stay
Phase 1 NSCLC data 1H 27
En fin, on my DD list as well (not a zero sum game)
$REPL $IMTX
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