Market Cap 514.42M
Revenue (ttm) 80.00M
Net Income (ttm) -9.73M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -12.16%
Debt to Equity Ratio 0.00
Volume 328,100
Avg Vol 696,204
Day's Range N/A - N/A
Shares Out 54.09M
Stochastic %K 81%
Beta 2.93
Analysts Strong Sell
Price Target $11.07

Company Profile

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers drug targets for potential treatment inherited aplastic anemias, such...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 651 8851
Address:
26 Landsdowne Street, Cambridge, United States
AnomalyDetective
AnomalyDetective Oct. 3 at 12:23 PM
#SPX $SPY S&P 500 Momentum Gauges in the longest positive weekly signal since 2020. Negative MG values are rising: http://vmbreakouts.com Active ETF portfolio +52.3% YTD with $GDXU +220.9% $LABU +45.3% and my forecast articles are available here: https://seekingalpha.com/article/4820291-total-return-breakouts-biotechs-accelerating-to-overtake-gold-rush MDA Breakout picks up +250.9% YTD in average cumulative weekly returns led by $CTMX $FULC picks this week and all new Week 41 MDA picks have been released for members: https://seekingalpha.com/mp/1201-value-momentum-breakouts/ Free breakout samples at: http://top.vmbreakouts.com
0 · Reply
AnomalyDetective
AnomalyDetective Oct. 2 at 4:08 PM
Our $ONDS prior mda breakout pick continues in strong positive MDA breakout conditions along with many other http://top.vmbreakouts.com prior selections. Follow the signals for the best results. Week 40 MDA picks extending the count to 340 weeks with at least one pick gaining over 10%: $CTMX $FULC for members. Now up over +248% YTD with all new Week 41 MDA breakout picks out after the close at: https://seekingalpha.com/mp/1201-value-momentum-breakouts ⚠️Major indices $QQQ $SPY #SPX hitting new highs led by #Tech #Gold #Biotech but watch the signals for any market changes live: http://vmbreakouts.com
0 · Reply
Quantumup
Quantumup Oct. 1 at 2:41 PM
Oppenheimer reiterated $FULC at an Outperform rating and a $15 price target: $XBI $AGIO $NVS $VRTX Oppenheimer said: We've been getting questions on how updated pociredir data later this year will impact FULC shares. For us, the readout is more "icing on the cake," rather than major binary because we already thought pociredir looked like a drug at the lower 12 mg dose. Absent any idiosyncratic toxicity or material weakening of efficacy, shares should continue to grind higher. However, given Fulcrum's recent run (shares are up 80% YTD vs. the XBI ahead 9%), it's fair to assume that the buyside's internal bar may be higher than our own. Based on our field work, that bar appears to be a 10% or higher HbF improvement. We believe that's achievable based on prior healthy volunteer data.
0 · Reply
biochirp
biochirp Oct. 1 at 2:38 PM
$FULC Global blood therapeutics got bought for 5.4B, they had a marketed drug (now pulled from market) and 2nd in PH2. So, once FULC clears PH1 with good data .. lets a market cap >1B
0 · Reply
highnihilism
highnihilism Sep. 30 at 12:06 PM
$EWTX Edgewise Therapeutics: 28 trades, $21K vs $15K avg (1.36x). $16K calls / $5K puts. $FULC Fulcrum Therapeutics: 27 trades, $16K vs $54K avg (0.30x). $16K calls / $0 puts. $PACB Pacific Biosciences: 42 trades, $18K vs $34K avg (0.52x). $16K calls / $2K puts. $ASND Ascendis Pharma: 20 trades, $18K vs $383K avg (0.05x). $16K calls / $2K puts.
0 · Reply
biochirp
biochirp Sep. 26 at 3:45 PM
$FULC wants to clear 10
0 · Reply
PKlee
PKlee Sep. 26 at 2:45 PM
$FULC what’s going on here?? Sudden jump??
0 · Reply
Chingying
Chingying Sep. 25 at 8:14 PM
$FULC What’s causing the epic run up ? I like the run up though. Data for higher dosage 20mg trial coming out by 12/31/2025.
0 · Reply
Doozio
Doozio Sep. 25 at 6:17 PM
$FULC 👀 MAMA it’s 🐒🍌🧠⏰♾️
0 · Reply
MarySmith1019
MarySmith1019 Sep. 21 at 3:36 PM
$FULC Biopharmaceutical growth. Testing resistance level. Volume confirmation needed. Sector momentum.
0 · Reply
Latest News on FULC
Fulcrum Therapeutics to Present at Upcoming Investor Meetings

Aug 26, 2025, 8:00 AM EDT - 5 weeks ago

Fulcrum Therapeutics to Present at Upcoming Investor Meetings


Fulcrum Therapeutics to Present at Upcoming Medical Meetings

May 29, 2025, 4:10 PM EDT - 4 months ago

Fulcrum Therapeutics to Present at Upcoming Medical Meetings


Fulcrum Therapeutics to Participate in Upcoming May Conferences

May 8, 2025, 4:05 PM EDT - 5 months ago

Fulcrum Therapeutics to Participate in Upcoming May Conferences


Fulcrum Therapeutics, Inc. (FULC) Q4 2024 Earnings Call Transcript

Feb 25, 2025, 10:58 PM EST - 7 months ago

Fulcrum Therapeutics, Inc. (FULC) Q4 2024 Earnings Call Transcript


Fulcrum Therapeutics, Inc. (FULC) Q3 2024 Earnings Call Transcript

Nov 13, 2024, 7:48 PM EST - 11 months ago

Fulcrum Therapeutics, Inc. (FULC) Q3 2024 Earnings Call Transcript


AnomalyDetective
AnomalyDetective Oct. 3 at 12:23 PM
#SPX $SPY S&P 500 Momentum Gauges in the longest positive weekly signal since 2020. Negative MG values are rising: http://vmbreakouts.com Active ETF portfolio +52.3% YTD with $GDXU +220.9% $LABU +45.3% and my forecast articles are available here: https://seekingalpha.com/article/4820291-total-return-breakouts-biotechs-accelerating-to-overtake-gold-rush MDA Breakout picks up +250.9% YTD in average cumulative weekly returns led by $CTMX $FULC picks this week and all new Week 41 MDA picks have been released for members: https://seekingalpha.com/mp/1201-value-momentum-breakouts/ Free breakout samples at: http://top.vmbreakouts.com
0 · Reply
AnomalyDetective
AnomalyDetective Oct. 2 at 4:08 PM
Our $ONDS prior mda breakout pick continues in strong positive MDA breakout conditions along with many other http://top.vmbreakouts.com prior selections. Follow the signals for the best results. Week 40 MDA picks extending the count to 340 weeks with at least one pick gaining over 10%: $CTMX $FULC for members. Now up over +248% YTD with all new Week 41 MDA breakout picks out after the close at: https://seekingalpha.com/mp/1201-value-momentum-breakouts ⚠️Major indices $QQQ $SPY #SPX hitting new highs led by #Tech #Gold #Biotech but watch the signals for any market changes live: http://vmbreakouts.com
0 · Reply
Quantumup
Quantumup Oct. 1 at 2:41 PM
Oppenheimer reiterated $FULC at an Outperform rating and a $15 price target: $XBI $AGIO $NVS $VRTX Oppenheimer said: We've been getting questions on how updated pociredir data later this year will impact FULC shares. For us, the readout is more "icing on the cake," rather than major binary because we already thought pociredir looked like a drug at the lower 12 mg dose. Absent any idiosyncratic toxicity or material weakening of efficacy, shares should continue to grind higher. However, given Fulcrum's recent run (shares are up 80% YTD vs. the XBI ahead 9%), it's fair to assume that the buyside's internal bar may be higher than our own. Based on our field work, that bar appears to be a 10% or higher HbF improvement. We believe that's achievable based on prior healthy volunteer data.
0 · Reply
biochirp
biochirp Oct. 1 at 2:38 PM
$FULC Global blood therapeutics got bought for 5.4B, they had a marketed drug (now pulled from market) and 2nd in PH2. So, once FULC clears PH1 with good data .. lets a market cap >1B
0 · Reply
highnihilism
highnihilism Sep. 30 at 12:06 PM
$EWTX Edgewise Therapeutics: 28 trades, $21K vs $15K avg (1.36x). $16K calls / $5K puts. $FULC Fulcrum Therapeutics: 27 trades, $16K vs $54K avg (0.30x). $16K calls / $0 puts. $PACB Pacific Biosciences: 42 trades, $18K vs $34K avg (0.52x). $16K calls / $2K puts. $ASND Ascendis Pharma: 20 trades, $18K vs $383K avg (0.05x). $16K calls / $2K puts.
0 · Reply
biochirp
biochirp Sep. 26 at 3:45 PM
$FULC wants to clear 10
0 · Reply
PKlee
PKlee Sep. 26 at 2:45 PM
$FULC what’s going on here?? Sudden jump??
0 · Reply
Chingying
Chingying Sep. 25 at 8:14 PM
$FULC What’s causing the epic run up ? I like the run up though. Data for higher dosage 20mg trial coming out by 12/31/2025.
0 · Reply
Doozio
Doozio Sep. 25 at 6:17 PM
$FULC 👀 MAMA it’s 🐒🍌🧠⏰♾️
0 · Reply
MarySmith1019
MarySmith1019 Sep. 21 at 3:36 PM
$FULC Biopharmaceutical growth. Testing resistance level. Volume confirmation needed. Sector momentum.
0 · Reply
biochirp
biochirp Sep. 18 at 5:08 PM
$KURA and $FULC gotta go
0 · Reply
SmartMoneyTradez
SmartMoneyTradez Sep. 5 at 11:48 PM
$MPW $FULC 20/50 ma bullish cross
0 · Reply
biochirp
biochirp Sep. 5 at 3:13 PM
$FULC that's that FU candle stick
0 · Reply
PortfolioCaptain
PortfolioCaptain Aug. 29 at 8:23 AM
$FULC Fulcrum Therapeutics Inc is a clinical stage genetic medicine company with development risks
0 · Reply
PreIPOX
PreIPOX Aug. 27 at 5:40 AM
$FULC sitting near support, reaction here will be critical.
0 · Reply
biochirp
biochirp Aug. 18 at 12:39 PM
$FULC $XBI https://endpoints.news/pfizers-sickle-cell-drug-candidate-fails-phase-3-trial/?u=0fe66aed-b490-4e96-849f-1f8ad5363ce8&s=email&c=ead60ced-048426a8-90400329&utm_medium=email&utm_campaign=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic&utm_content=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic+CID_7bcdfd025fd420116033241d1ffed7a0&utm_source=ENDPOINTS%20emails&utm_term=Pfizers%20sickle%20cell%20drug%20candidate%20fails%20Phase%203%20trial $PFE
1 · Reply
Kai506
Kai506 Aug. 6 at 7:04 PM
$FULC Followed in on the massive volume spike. That's not retail money. Possible news leak after market close...I'm hoping
0 · Reply
biochirp
biochirp Aug. 5 at 1:06 PM
$FULC cmon JNJ now is the time
0 · Reply
StockScanners
StockScanners Aug. 5 at 1:36 AM
$FULC still on watch
0 · Reply
BioTechHealthX
BioTechHealthX Aug. 4 at 2:50 AM
$FULC Pociredir’s strong efficacy, clean safety, and massive potential market make Fulcrum one of the most exciting biotech plays right now. https://biotechhealthx.com/biotech-news/fulcrum-therapeutics-fulcs-stunning-trial-results-could-make-it-the-next-biotech-breakout/
0 · Reply
StockScanners
StockScanners Aug. 2 at 6:29 PM
$FULC needs to hold above 6
0 · Reply
edvquye
edvquye Aug. 1 at 5:37 PM
$FULC in here
0 · Reply