Market Cap 372.15M
Revenue (ttm) 80.00M
Net Income (ttm) -9.73M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -12.16%
Debt to Equity Ratio 0.00
Volume 362,200
Avg Vol 728,494
Day's Range N/A - N/A
Shares Out 54.09M
Stochastic %K 74%
Beta 2.47
Analysts Strong Sell
Price Target $11.07

Company Profile

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers drug targets for potential treatment inherited aplastic anemias, such...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 651 8851
Address:
26 Landsdowne Street, Cambridge, United States
biochirp
biochirp Aug. 18 at 12:39 PM
$FULC $XBI https://endpoints.news/pfizers-sickle-cell-drug-candidate-fails-phase-3-trial/?u=0fe66aed-b490-4e96-849f-1f8ad5363ce8&s=email&c=ead60ced-048426a8-90400329&utm_medium=email&utm_campaign=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic&utm_content=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic+CID_7bcdfd025fd420116033241d1ffed7a0&utm_source=ENDPOINTS%20emails&utm_term=Pfizers%20sickle%20cell%20drug%20candidate%20fails%20Phase%203%20trial $PFE
1 · Reply
Kai506
Kai506 Aug. 6 at 7:04 PM
$FULC Followed in on the massive volume spike. That's not retail money. Possible news leak after market close...I'm hoping
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biochirp
biochirp Aug. 5 at 1:06 PM
$FULC cmon JNJ now is the time
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StockScanners
StockScanners Aug. 5 at 1:36 AM
$FULC still on watch
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BioTechHealthX
BioTechHealthX Aug. 4 at 2:50 AM
$FULC Pociredir’s strong efficacy, clean safety, and massive potential market make Fulcrum one of the most exciting biotech plays right now. https://biotechhealthx.com/biotech-news/fulcrum-therapeutics-fulcs-stunning-trial-results-could-make-it-the-next-biotech-breakout/
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StockScanners
StockScanners Aug. 2 at 6:29 PM
$FULC needs to hold above 6
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edvquye
edvquye Aug. 1 at 5:37 PM
$FULC in here
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alfafc
alfafc Jul. 30 at 4:52 PM
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JarvisFlow
JarvisFlow Jul. 30 at 2:27 PM
RBC Capital updates rating for Fulcrum Therapeutics ( $FULC ) to Sector Perform, target set at 4 → 5.
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Dkll303
Dkll303 Jul. 30 at 12:22 PM
$AGIO $FULC Good olé HC WAINWRIGHT…sucking in investors to FULC …hahahaha .. Still at it …copy cat of LUTNICK- Cantor Fitz and his pathetic “ outperforms “ that DIE and never go any where …AGIO
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Latest News on FULC
Fulcrum Therapeutics to Present at Upcoming Medical Meetings

May 29, 2025, 4:10 PM EDT - 3 months ago

Fulcrum Therapeutics to Present at Upcoming Medical Meetings


Fulcrum Therapeutics to Participate in Upcoming May Conferences

May 8, 2025, 4:05 PM EDT - 3 months ago

Fulcrum Therapeutics to Participate in Upcoming May Conferences


Fulcrum Therapeutics, Inc. (FULC) Q4 2024 Earnings Call Transcript

Feb 25, 2025, 10:58 PM EST - 6 months ago

Fulcrum Therapeutics, Inc. (FULC) Q4 2024 Earnings Call Transcript


Fulcrum Therapeutics, Inc. (FULC) Q3 2024 Earnings Call Transcript

Nov 13, 2024, 7:48 PM EST - 10 months ago

Fulcrum Therapeutics, Inc. (FULC) Q3 2024 Earnings Call Transcript


FMR LLC's Strategic Reduction in Fulcrum Therapeutics Inc Shares

Oct 7, 2024, 2:03 PM EDT - 11 months ago

FMR LLC's Strategic Reduction in Fulcrum Therapeutics Inc Shares


biochirp
biochirp Aug. 18 at 12:39 PM
$FULC $XBI https://endpoints.news/pfizers-sickle-cell-drug-candidate-fails-phase-3-trial/?u=0fe66aed-b490-4e96-849f-1f8ad5363ce8&s=email&c=ead60ced-048426a8-90400329&utm_medium=email&utm_campaign=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic&utm_content=976%20-%20Gene%20therapy%20biotechs%20313M%20raise%20Novos%20Wegovy%20nabs%20MASH%20approval%20Basic+CID_7bcdfd025fd420116033241d1ffed7a0&utm_source=ENDPOINTS%20emails&utm_term=Pfizers%20sickle%20cell%20drug%20candidate%20fails%20Phase%203%20trial $PFE
1 · Reply
Kai506
Kai506 Aug. 6 at 7:04 PM
$FULC Followed in on the massive volume spike. That's not retail money. Possible news leak after market close...I'm hoping
0 · Reply
biochirp
biochirp Aug. 5 at 1:06 PM
$FULC cmon JNJ now is the time
0 · Reply
StockScanners
StockScanners Aug. 5 at 1:36 AM
$FULC still on watch
0 · Reply
BioTechHealthX
BioTechHealthX Aug. 4 at 2:50 AM
$FULC Pociredir’s strong efficacy, clean safety, and massive potential market make Fulcrum one of the most exciting biotech plays right now. https://biotechhealthx.com/biotech-news/fulcrum-therapeutics-fulcs-stunning-trial-results-could-make-it-the-next-biotech-breakout/
0 · Reply
StockScanners
StockScanners Aug. 2 at 6:29 PM
$FULC needs to hold above 6
0 · Reply
edvquye
edvquye Aug. 1 at 5:37 PM
$FULC in here
0 · Reply
alfafc
alfafc Jul. 30 at 4:52 PM
0 · Reply
JarvisFlow
JarvisFlow Jul. 30 at 2:27 PM
RBC Capital updates rating for Fulcrum Therapeutics ( $FULC ) to Sector Perform, target set at 4 → 5.
0 · Reply
Dkll303
Dkll303 Jul. 30 at 12:22 PM
$AGIO $FULC Good olé HC WAINWRIGHT…sucking in investors to FULC …hahahaha .. Still at it …copy cat of LUTNICK- Cantor Fitz and his pathetic “ outperforms “ that DIE and never go any where …AGIO
0 · Reply
Quantumup
Quantumup Jul. 30 at 12:10 PM
H.C. Wainwright yesterday⬆️ $FULC to Buy-$12 from Neutral-$4. $PFE $VRTX $QURE SGMO $AGIO CRSP BLUE - CG H.C. Wainwright said, "Today's 12mg dataset from Fulcrum's PIONEER Phase 1b trial builds meaningfully on prior mechanistic and early clinical observations, offering a tangible glimpse into the translational potential of HbF induction in sickle cell disease (SCD). We view the absolute increase in fetal hemoglobin (HbF), combined with improvements in key hematologic and hemolytic parameters, as validation of pociredir's ability to recapitulate the protective biology observed in hereditary persistence of fetal hemoglobin (HPFH). This matters clinically because patients with HPFH exhibit far fewer vaso-occlusive complications despite possessing the same ß-globin mutation. H.C. Wainwright additionally said:
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d_risk
d_risk Jul. 30 at 4:30 AM
$FULC - Fulcrum Therapeutics Inc. Common Stock - 10Q - Updated Risk Factors FULC’s 10-Q reveals heightened risks from ongoing operating losses, Phase 3 failure-driven R&D cuts, clinical and regulatory uncertainties, intensified IP and commercialization challenges, new tax and pricing pressures, expanded compliance and cybersecurity risks, and concentrated ownership with anti-takeover measures. #Biotechnology #FinancialRisk #IntellectualProperty #RegulatoryRisk #ClinicalTrials 🟢 Added 🟠 Removed https://d-risk.ai/FULC/10-Q/2025-07-29
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alfafc
alfafc Jul. 29 at 3:39 PM
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_www_larval_com_
_www_larval_com_ Jul. 29 at 2:42 PM
$FULC just stumbled -4% lower to -7% (~5Mv) moments ago, 08/15 options, follow for more volatility.
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biochirp
biochirp Jul. 29 at 2:14 PM
$FULC guys the data was actually good
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NSAR
NSAR Jul. 29 at 2:10 PM
$FULC very positive comments from the very first analyst since the release!!!!!
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Lets_Go_Brndn
Lets_Go_Brndn Jul. 29 at 2:05 PM
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NSAR
NSAR Jul. 29 at 1:59 PM
$FULC from what I’m reading is all positive. The stock was up close to 30% premarket and then sold off and it was down 20% premarket and now it’s back to even. The first analyst comment, reiterated, outperform, and raise the price target. The company is flooded with cash four dollars per share no debt.
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theoptionsplug
theoptionsplug Jul. 29 at 1:52 PM
$FULC CLINICAL TRIALS: PROMISING PHASE 1B RESULTS FOR SICKLE CELL DRUG 💊
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paddypablo
paddypablo Jul. 29 at 1:13 PM
$FULC ✈️✈️🙌🙌🙌
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biolevity
biolevity Jul. 29 at 1:13 PM
Initial reaction to $FULC data were -ve, but after the call the stock has rebounded. Think this is going higher....
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