Market Cap 704.48M
Revenue (ttm) 69.65M
Net Income (ttm) -81.27M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -116.68%
Debt to Equity Ratio 0.00
Volume 1,399,900
Avg Vol 1,492,720
Day's Range N/A - N/A
Shares Out 104.68M
Stochastic %K 75%
Beta 2.20
Analysts Strong Sell
Price Target $11.29

Company Profile

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor an...

Industry: Diagnostics & Research
Sector: Healthcare
Phone: 650 752 1300
Fax: 650 752 1301
Address:
6600 Dumbarton Circle, Fremont, United States
BioTechNoir
BioTechNoir Apr. 19 at 11:08 PM
$PSNL AACR podium tomorrow 💪🏼
0 · Reply
LukasWo
LukasWo Apr. 19 at 10:10 PM
$PSNL now that the Iran conflict is almost certain to intensify after the ceasefire ends, looks like more turbulence ahead.... just when one thought he can finally catch a break
0 · Reply
ExNoose
ExNoose Apr. 19 at 6:26 AM
$PSNL Did you know? Roche spent a decade trying to own the full cancer patient journey. FMI acquisition for diagnosis. Then tried to get into MRD monitoring. First attempt, sued Stanford and Foresight in 2024 trying to claim their ultra-sensitive PhasED-Seq technology was built on Roche's trade secrets. Lost. Settled for a narrow NHL licence. Foresight went to Natera. So they bought SAGA. $595M. One covered indication. Their only remaining option. Why not $PSNL though? Merck owns 13.4% of Personalis. Merck and Roche are direct competitors, both selling PD-1 inhibitors fighting for the same cancer patients every day. Keytruda vs Tecentriq. Roche acquiring $PSNL would hand their biggest competitor's most critical asset...the sequencing infrastructure for Merck's personalised cancer vaccine programme to Roche. Merck will never allow that. SAGA was acquirable. $PSNL is not. Not by Roche.
1 · Reply
ExNoose
ExNoose Apr. 19 at 5:37 AM
$PSNL Did you know? Natera already had Signatera Exome. Then built Signatera Genome, their own WGS version to close the sensitivity gap with $PSNL. Then acquired Foresight, a completely different MRD technology. A company confident in its technology doesn't acquire a third MRD platform... Natera is the volume leader. Nobody disputes that, but volume leadership and technology leadership are different things. If Signatera Genome solved the sensitivity problem then why buy Foresight? The answer is, it didn't. And they know it. Meanwhile Foresight CLARITY can't inherit Signatera's Medicare coverage. Different technology. Different dossier. Different MolDX review. 2-3 years minimum for solid tumour coverage. $PSNL has breast and lung covered today. IO pending. CRC coming... Natera leads in volume. $PSNL leads in technology. Doctors will choose what's best for their patient!
0 · Reply
RockyMontana
RockyMontana Apr. 18 at 4:41 PM
$PSNL vs $TMO 2016-2018
0 · Reply
RockyMontana
RockyMontana Apr. 18 at 8:50 AM
1 · Reply
lucianw
lucianw Apr. 17 at 8:34 PM
$PSNL Well performance over the past few weeks has been pathetic and it is simply not participating in the rebound. I took a look at my watchlist and it seems most of those weak performers lack institutional interests, many of them are penny stocks. It might sound ridiculous given the progress we have made but it is just the harsh truth… mgt really needs to up the game now
3 · Reply
lucianw
lucianw Apr. 17 at 4:21 PM
$PSNL with Saga and Foresight gone, we seem to be the only feasible target for acquisition. Just saying.
0 · Reply
LukasWo
LukasWo Apr. 17 at 8:13 AM
$PSNL why are we trending? I see no news
1 · Reply
ExNoose
ExNoose Apr. 17 at 7:23 AM
$PSNL Did you know? While PAMA cuts loom for Natera and GH, timing works in favour of PSNL! Medicare lab fee cuts of up to 15% per year are scheduled to resume January 2027. That's a real headwind for tests priced years ago but PSNL is different! NeXT Personal breast cancer Medicare reimbursement: $4.X,266 per test, set December 2025. Confirmed in SEC filing. Lung cancer coverage: effective January 2026. Rates freshly set. PAMA's 2027 cuts are based on private payer data collected January - June 2025. NeXT Personal had zero Medicare revenue before October 2025. No data = no PAMA rate cut mechanism. CMS uses crosswalk/gapfill for codes without reporting data. Competitors built revenue on rates set years ago. $PSNL starts fresh!
1 · Reply
Latest News on PSNL
Personalis Reports Third Quarter 2025 Financial Results

Nov 4, 2025, 4:01 PM EST - 5 months ago

Personalis Reports Third Quarter 2025 Financial Results


Personalis to Announce Third Quarter 2025 Financial Results

Oct 21, 2025, 4:01 PM EDT - 6 months ago

Personalis to Announce Third Quarter 2025 Financial Results


Personalis to Participate in Upcoming Investor Conferences

Aug 27, 2025, 4:01 PM EDT - 8 months ago

Personalis to Participate in Upcoming Investor Conferences


Personalis Reports Second Quarter 2025 Financial Results

Aug 5, 2025, 4:01 PM EDT - 9 months ago

Personalis Reports Second Quarter 2025 Financial Results


Personalis to Announce Second Quarter 2025 Financial Results

Jul 22, 2025, 4:01 PM EDT - 9 months ago

Personalis to Announce Second Quarter 2025 Financial Results


Personalis Reports First Quarter 2025 Financial Results

May 6, 2025, 4:01 PM EDT - 1 year ago

Personalis Reports First Quarter 2025 Financial Results


Personalis to Announce First Quarter 2025 Financial Results

Apr 22, 2025, 4:01 PM EDT - 1 year ago

Personalis to Announce First Quarter 2025 Financial Results


Personalis and Tempus Expand Collaboration to Biopharma

Dec 16, 2024, 8:00 AM EST - 1 year ago

Personalis and Tempus Expand Collaboration to Biopharma

TEM


Personalis to Participate at Upcoming Investor Conferences

Nov 20, 2024, 4:01 PM EST - 1 year ago

Personalis to Participate at Upcoming Investor Conferences


Personalis Reports Third Quarter 2024 Financial Results

Nov 6, 2024, 4:01 PM EST - 1 year ago

Personalis Reports Third Quarter 2024 Financial Results


Personalis to Announce Third Quarter 2024 Financial Results

Oct 23, 2024, 4:01 PM EDT - 1 year ago

Personalis to Announce Third Quarter 2024 Financial Results


BioTechNoir
BioTechNoir Apr. 19 at 11:08 PM
$PSNL AACR podium tomorrow 💪🏼
0 · Reply
LukasWo
LukasWo Apr. 19 at 10:10 PM
$PSNL now that the Iran conflict is almost certain to intensify after the ceasefire ends, looks like more turbulence ahead.... just when one thought he can finally catch a break
0 · Reply
ExNoose
ExNoose Apr. 19 at 6:26 AM
$PSNL Did you know? Roche spent a decade trying to own the full cancer patient journey. FMI acquisition for diagnosis. Then tried to get into MRD monitoring. First attempt, sued Stanford and Foresight in 2024 trying to claim their ultra-sensitive PhasED-Seq technology was built on Roche's trade secrets. Lost. Settled for a narrow NHL licence. Foresight went to Natera. So they bought SAGA. $595M. One covered indication. Their only remaining option. Why not $PSNL though? Merck owns 13.4% of Personalis. Merck and Roche are direct competitors, both selling PD-1 inhibitors fighting for the same cancer patients every day. Keytruda vs Tecentriq. Roche acquiring $PSNL would hand their biggest competitor's most critical asset...the sequencing infrastructure for Merck's personalised cancer vaccine programme to Roche. Merck will never allow that. SAGA was acquirable. $PSNL is not. Not by Roche.
1 · Reply
ExNoose
ExNoose Apr. 19 at 5:37 AM
$PSNL Did you know? Natera already had Signatera Exome. Then built Signatera Genome, their own WGS version to close the sensitivity gap with $PSNL. Then acquired Foresight, a completely different MRD technology. A company confident in its technology doesn't acquire a third MRD platform... Natera is the volume leader. Nobody disputes that, but volume leadership and technology leadership are different things. If Signatera Genome solved the sensitivity problem then why buy Foresight? The answer is, it didn't. And they know it. Meanwhile Foresight CLARITY can't inherit Signatera's Medicare coverage. Different technology. Different dossier. Different MolDX review. 2-3 years minimum for solid tumour coverage. $PSNL has breast and lung covered today. IO pending. CRC coming... Natera leads in volume. $PSNL leads in technology. Doctors will choose what's best for their patient!
0 · Reply
RockyMontana
RockyMontana Apr. 18 at 4:41 PM
$PSNL vs $TMO 2016-2018
0 · Reply
RockyMontana
RockyMontana Apr. 18 at 8:50 AM
1 · Reply
lucianw
lucianw Apr. 17 at 8:34 PM
$PSNL Well performance over the past few weeks has been pathetic and it is simply not participating in the rebound. I took a look at my watchlist and it seems most of those weak performers lack institutional interests, many of them are penny stocks. It might sound ridiculous given the progress we have made but it is just the harsh truth… mgt really needs to up the game now
3 · Reply
lucianw
lucianw Apr. 17 at 4:21 PM
$PSNL with Saga and Foresight gone, we seem to be the only feasible target for acquisition. Just saying.
0 · Reply
LukasWo
LukasWo Apr. 17 at 8:13 AM
$PSNL why are we trending? I see no news
1 · Reply
ExNoose
ExNoose Apr. 17 at 7:23 AM
$PSNL Did you know? While PAMA cuts loom for Natera and GH, timing works in favour of PSNL! Medicare lab fee cuts of up to 15% per year are scheduled to resume January 2027. That's a real headwind for tests priced years ago but PSNL is different! NeXT Personal breast cancer Medicare reimbursement: $4.X,266 per test, set December 2025. Confirmed in SEC filing. Lung cancer coverage: effective January 2026. Rates freshly set. PAMA's 2027 cuts are based on private payer data collected January - June 2025. NeXT Personal had zero Medicare revenue before October 2025. No data = no PAMA rate cut mechanism. CMS uses crosswalk/gapfill for codes without reporting data. Competitors built revenue on rates set years ago. $PSNL starts fresh!
1 · Reply
BeeDecay
BeeDecay Apr. 17 at 7:19 AM
$PSNL As mentioned by others, the MRD landscape is changing, with big players scooping up the smaller ones. Saga, having an excellent though narrow test, will now thrive under Roche. Foresight will thrive under the wings of Natera. Money, a main hurdle of many high tech companies, is gone. So is the inexperience about marketing and sales. As mentioned by @ExNoose the good thing is that they cannot buy time. Time needed for regulatory approvals and reimbursement. Question remains: why were Foresight AND Saga acquired, not Personalis? No, it's not the few 100k bucks more that would have cost. Peanuts. Is it the stronger believe in their technology vs ours? Numbers (sensitivity) we see from company and scientific communication you would think not. Is it the strategic mess Chris made by having two very large companies as shareholders (MRK and TEM)? It probably is. I never liked that. We will have to go for it alone. And that does not feel comfortable.
1 · Reply
t2026
t2026 Apr. 17 at 2:20 AM
All done with $RVMD and moving on to this. $PSNL MRD testing is the future Tempus is the leader in NGS. When Tempus unleashes this test it’s game over for natera for several reasons. Oncologists - all things being equal we like a one stop shop Tissue NGS, liquid NGS, and MRD testing all under one roof sign me up. Tempus has the best platform. But let’s get to the real reason why PSNL might be the leader. Stage II / III colon cancer on the fence about chemotherapy and +MRD give adjuvant chemotherapy What if the test is negative are you really going to skip chemo with natera in low shedding tumors ? I’ll take the 1800 variants tracked with personalis over natera’s 64 anyday of the week. No one is married to natera, first to market means nothing. This is a gold mine if they execute properly.
0 · Reply
ExNoose
ExNoose Apr. 16 at 7:43 PM
$PSNL Yes, competition just got tougher. Roche/Foundation Medicine entering MRD with $595M behind them is real. Natera absorbed Foresight. This isn't the same landscape as 12 months ago. But MRD isn't winner-take-all. Oncologists will use multiple tests across cancer types. What Personalis needs is to win enough... not everything. IO coverage arriving. CRC dossier submitted. Neoadjuvant breast close behind. Tempus driving volume through 50%+ of US oncologists. Biopharma clinical trial revenue growing. In 2-3 years I see a company with 4-5 covered indications, $150-200M revenue trajectory, improving margins, and serious acquisition interest. The bear case is Roche moves faster than expected and IO gets delayed. Thats a real risk. The bull case is 12 years of evidence, patents competitors pay royalties on and a technology that nobody has beaten head-to-head at scale. Also, cancer vaccines is something that only PSNL is involved in to. It could be transformational.
3 · Reply
BioTechNoir
BioTechNoir Apr. 16 at 3:59 PM
$PSNL expect to see i/o by end of May, but hoping sooner 🤠
0 · Reply
Skibum77
Skibum77 Apr. 16 at 1:28 PM
$PSNL 20 days until next CC. Pray for a better opening monologue from Aaron
0 · Reply
magnitudeFC
magnitudeFC Apr. 16 at 1:24 PM
$PSNL Roche who own Foundation just acquired Saga for $500M… bullish or bearish $PSNL? https://www.foundationmedicine.com/press-release/saga-diagnostics-mrd-platform
1 · Reply
magnitudeFC
magnitudeFC Apr. 16 at 11:48 AM
$PSNL we are coming up on 10 months since IO approval submission…
0 · Reply
marcopol0
marcopol0 Apr. 15 at 10:31 PM
$PSNL Should we just rebrand to http://personalis.ai? It’s getting exhausting being treated like we’re some random SaaS tool instead of the team literally helping cure cancer.
0 · Reply
ExNoose
ExNoose Apr. 15 at 8:00 PM
$PSNL 2/3 of the shares gone already. IO approval will shake them a lot.
0 · Reply
magnitudeFC
magnitudeFC Apr. 15 at 5:21 PM
$PSNL Does anyone know at what time they are speaking at Needham?
0 · Reply
GGator
GGator Apr. 15 at 11:52 AM
$PSNL Patiently waiting.
0 · Reply
RockyMontana
RockyMontana Apr. 14 at 3:14 PM
$PSNL we’ll rip higher.
0 · Reply