Market Cap 1.64B
Revenue (ttm) 0.00
Net Income (ttm) -317.42M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 4,354,037
Avg Vol 2,618,420
Day's Range N/A - N/A
Shares Out 113.67M
Stochastic %K 33%
Beta 1.16
Analysts Strong Sell
Price Target $44.07

Company Profile

Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therap...

Industry: Biotechnology
Sector: Healthcare
Phone: 781 786 8230
Fax: 781 786 8866
Address:
1560 Trapelo Road, Waltham, United States
Chomo
Chomo Jun. 17 at 5:26 PM
$DYN someone knew about the news yesterday and sold the stock, yesterday volume was almos 3X average
1 · Reply
Jewstock
Jewstock Jun. 17 at 5:03 PM
$DYN giving me no choice but to average down
0 · Reply
S_Franconi
S_Franconi Jun. 17 at 2:31 PM
$DYN However, sometimes new information may come to light that could merit changes to endpoints during the course of a trial. This new information might include, for example, results from other trials or identification of better biomarkers or surrogate outcome measures. Such changes can allow incorporation of up-to-date knowledge into the trial design. However, changes to endpoints can also compromise the scientific integrity of a trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC1852589/
1 · Reply
Jewstock
Jewstock Jun. 17 at 2:19 PM
$DYN ouch!
0 · Reply
S_Franconi
S_Franconi Jun. 17 at 1:58 PM
$DYN Buying.
0 · Reply
_www_larval_com_
_www_larval_com_ Jun. 17 at 1:37 PM
$JZ -15%[-13%] $CRML 12%[-4%] $RGC -11%[11%] $DYN -9%[-15%] $SRM -8%[-17%] most notable movement within the first minutes of trading.
0 · Reply
DonCorleone77
DonCorleone77 Jun. 17 at 12:45 PM
$DYN Dyne Therapeutics sinks more than 20% after changing study endpoint Shares of Dyne Therapeutics are moving lower after the company revised the ongoing registrational expansion cohort in the ACHIEVE trial for DYNE-101 for the treatment of myotonic dystrophy type 1. The primary endpoint is change from baseline in middle finger myotonia as measured by video hand opening time at six months, compared to placebo. Dyne and the FDA agreed that the next step toward accelerated approval was to submit for review the revised protocol for the Registrational Expansion Cohort of the ACHIEVE trial with video hand opening time as the primary endpoint, to serve as an intermediate clinical endpoint. In June, Dyne submitted the revised protocol to the FDA. The company plans to complete enrollment in the registrational expansion cohort in Q4. Shares of Dyne are down around 23% in premarket trading.
1 · Reply
Rounderssss4
Rounderssss4 Jun. 17 at 11:49 AM
$DYN timing for approval pushed back to late 26
1 · Reply
southernboytrader067
southernboytrader067 Jun. 16 at 8:44 PM
$DYN Dyne Therapeutics to Host Investor Conference Call and Webcast to Provide Update on DYNE-101 for Myotonic Dystrophy Type 1, Tomorrow Tuesday, June 17 at 8:00 a.m. ET
1 · Reply
BlakeCanyon50
BlakeCanyon50 Jun. 16 at 8:39 PM
$DYN Wow!!! What happened?
1 · Reply
Latest News on DYN
Dyne Therapeutics to Present at Stifel 2025 Virtual CNS Forum

Mar 11, 2025, 7:30 AM EDT - 3 months ago

Dyne Therapeutics to Present at Stifel 2025 Virtual CNS Forum


Dyne Therapeutics to Present at Upcoming Investor Conferences

Nov 7, 2024, 4:15 PM EST - 7 months ago

Dyne Therapeutics to Present at Upcoming Investor Conferences


Chomo
Chomo Jun. 17 at 5:26 PM
$DYN someone knew about the news yesterday and sold the stock, yesterday volume was almos 3X average
1 · Reply
Jewstock
Jewstock Jun. 17 at 5:03 PM
$DYN giving me no choice but to average down
0 · Reply
S_Franconi
S_Franconi Jun. 17 at 2:31 PM
$DYN However, sometimes new information may come to light that could merit changes to endpoints during the course of a trial. This new information might include, for example, results from other trials or identification of better biomarkers or surrogate outcome measures. Such changes can allow incorporation of up-to-date knowledge into the trial design. However, changes to endpoints can also compromise the scientific integrity of a trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC1852589/
1 · Reply
Jewstock
Jewstock Jun. 17 at 2:19 PM
$DYN ouch!
0 · Reply
S_Franconi
S_Franconi Jun. 17 at 1:58 PM
$DYN Buying.
0 · Reply
_www_larval_com_
_www_larval_com_ Jun. 17 at 1:37 PM
$JZ -15%[-13%] $CRML 12%[-4%] $RGC -11%[11%] $DYN -9%[-15%] $SRM -8%[-17%] most notable movement within the first minutes of trading.
0 · Reply
DonCorleone77
DonCorleone77 Jun. 17 at 12:45 PM
$DYN Dyne Therapeutics sinks more than 20% after changing study endpoint Shares of Dyne Therapeutics are moving lower after the company revised the ongoing registrational expansion cohort in the ACHIEVE trial for DYNE-101 for the treatment of myotonic dystrophy type 1. The primary endpoint is change from baseline in middle finger myotonia as measured by video hand opening time at six months, compared to placebo. Dyne and the FDA agreed that the next step toward accelerated approval was to submit for review the revised protocol for the Registrational Expansion Cohort of the ACHIEVE trial with video hand opening time as the primary endpoint, to serve as an intermediate clinical endpoint. In June, Dyne submitted the revised protocol to the FDA. The company plans to complete enrollment in the registrational expansion cohort in Q4. Shares of Dyne are down around 23% in premarket trading.
1 · Reply
Rounderssss4
Rounderssss4 Jun. 17 at 11:49 AM
$DYN timing for approval pushed back to late 26
1 · Reply
southernboytrader067
southernboytrader067 Jun. 16 at 8:44 PM
$DYN Dyne Therapeutics to Host Investor Conference Call and Webcast to Provide Update on DYNE-101 for Myotonic Dystrophy Type 1, Tomorrow Tuesday, June 17 at 8:00 a.m. ET
1 · Reply
BlakeCanyon50
BlakeCanyon50 Jun. 16 at 8:39 PM
$DYN Wow!!! What happened?
1 · Reply
S_Franconi
S_Franconi Jun. 11 at 4:12 PM
0 · Reply
Avocado_smash
Avocado_smash Jun. 7 at 9:56 PM
$DYN Monday: 14.53 - 15.56+ Open, trade and closed below that range, pullback might start.
0 · Reply
Jewstock
Jewstock Jun. 6 at 3:35 PM
$DYN I love you
0 · Reply
waterlock
waterlock Jun. 6 at 2:27 PM
$DYN say this again, dyne has the best DM1 asset. $SRPT $MGTX $RGNX
1 · Reply
Jewstock
Jewstock Jun. 2 at 4:18 PM
0 · Reply
S_Franconi
S_Franconi Jun. 2 at 2:53 PM
$IMTX $EWTX $DYN Gainer list - this year.
0 · Reply
S_Franconi
S_Franconi May. 30 at 7:23 PM
0 · Reply
S_Franconi
S_Franconi May. 30 at 1:57 PM
$DYN Added.
0 · Reply
Florestan
Florestan May. 27 at 3:52 PM
$MSCLF https://musculardystrophynews.com/news/dmd-treatment-sat-3247-safe-trial-shows-early-signs-efficacy/ $DYN $EWTX $SRPT
2 · Reply
Florestan
Florestan May. 22 at 1:32 PM
$MSCLF grip strength doubling is unheard of in DMD. This is supposedly impossible from the known literature. They literally did the impossible helping 18+ patients, a cohort long written off as dead men walking by every other drug companies working on Duchenne. $SRPT $CAPR $DYN
2 · Reply
Florestan
Florestan May. 22 at 12:17 PM
$MSCLF "Potential trend to improved grip strength observed, with average strength across the study participants doubling from ~2kg to ~4kg" 🚨 https://ir.satellos.com/news/news-details/2025/Satellos-Announces-Encouraging-Functional-Data-from-the-28-day-Phase-1b-Open-Label-Trial-of-SAT-3247-in-Adults-with-Duchenne-Muscular-Dystrophy/default.aspx $SRPT $DYN $CAPR
0 · Reply
Florestan
Florestan May. 20 at 5:27 PM
$MSCLF only a couple more days for 1b results, and reminder: this is a dystrophin-independent pathway they are targeting that will apply to all DMD patients. They will have US sites up and running after FDA grants IND, if you know a DMD kid, let them know of this treatment. "Satellos will share data from its Phase 1b study in adult Duchenne muscle disease (DMD) patients in the second quarter, said Chief Executive Frank Gleeson." "As a company, we believe we are well positioned to advance our novel drug into a randomized, placebo-controlled Phase 2 POC [proof-of-concept] trial in pediatric DMD patients as our next major development step," Gleeson said. "This study will be designed to further assess the safety of SAT-3247 in a key pediatric population, while exploring its possible utility in restoring the body's ability to repair and regenerate damaged or lost muscle." $CAPR $SRPT $DYN
1 · Reply