Market Cap 74.51M
Revenue (ttm) 0.00
Net Income (ttm) -102.33M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.19
Volume 5,670,782
Avg Vol 254,990
Day's Range N/A - N/A
Shares Out 60.57M
Stochastic %K 62%
Beta 0.05
Analysts Strong Sell
Price Target $7.80

Company Profile

Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. The company focuses on advancing a targeted immunotherapy drug candidate Sabirnetug (ACU193), a recombinant humanized immunoglobulin gamma 2, which has completed the INTERCEPT-AD phase 1 clinical trial and in ALTITUDE-AD phase 2 clinical trial to target soluble amyloid-beta oligomers. It has a collaboration and license agreement with Halozyme, Inc. for t...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 344 4190
Address:
1210-1220 Washington St., Suite 210, Newton, United States
vaselineguy
vaselineguy Jun. 24 at 3:11 AM
$ABOS still here
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JarvisFlow
JarvisFlow Jun. 17 at 12:00 PM
Citigroup has updated their rating for Acumen Pharmaceuticals ( $ABOS ) to Buy with a price target of 4.
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DougieFreshPicks
DougieFreshPicks Jun. 9 at 11:39 PM
$ABOS on the list 👍
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somaopp
somaopp Jun. 8 at 5:53 PM
$ABOS Looks somewhat promising but its a one trick pony..
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Bio_Oko
Bio_Oko May. 23 at 1:59 PM
$AVXL Just added to my Video Channel and patreon.com/Bio_Oko blog a short video/presentation on $ABOS . Contains references to ANAVEX . https://youtu.be/kvy9tUfyqBc
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vaselineguy
vaselineguy Apr. 11 at 8:26 PM
$ABOS here we gooo
1 · Reply
vaselineguy
vaselineguy Apr. 4 at 4:23 PM
$ABOS grabbed
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DonCorleone77
DonCorleone77 Apr. 2 at 11:29 AM
$ABOS Acumen presented results from pTau217 assay in Phase 2 ALTITUDE-AD trial Acumen Pharmaceuticals presented extended results from its validated research-use plasma pTau217 assay to screen potential participants in the ongoing Phase 2 ALTITUDE-AD clinical trial of sabirnetug, showing this strategy has performed as intended. The company presented the results during an oral presentation at the International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders, AD/PD, in Vienna, Austria, from April 1-5, 2025, and will deliver an encore presentation at the American Academy of Neurology. AAN, Annual Meeting in San Diego, Calif., from April 5-9, 2025. Acumen is also presenting posters on methods of interrogating the binding of AbetaOs to a model of human neurons, methods to advance Abeta selectivity measurements and early effects of sabirnetug on synaptic biomarkers in AD.
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ElysiumAdvisors
ElysiumAdvisors Mar. 31 at 3:55 PM
$ABOS Some math here: Net cash of $200M, market cap at $65M. Assuming half 2027 cash burn rate and news of the phase 2 second half of 2026 that means that the current market expectations is not only that 100% the study fails but also that they spend over $140M. Market could be right, but I still think we get a move to the upside on repricing of drug % probability of success.
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JarvisFlow
JarvisFlow Mar. 28 at 1:37 PM
UBS updates rating for Acumen Pharmaceuticals ( $ABOS ) to Buy, target set at 6 → 4.
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Latest News on ABOS
Lucy Therapeutics Appoints Kim Drapkin as Board Chair

Oct 15, 2024, 8:00 AM EDT - 9 months ago

Lucy Therapeutics Appoints Kim Drapkin as Board Chair

LENZ


Acumen Pharmaceuticals to Host Virtual R&D Day on Oct. 2, 2024

Sep 25, 2024, 4:00 PM EDT - 9 months ago

Acumen Pharmaceuticals to Host Virtual R&D Day on Oct. 2, 2024


Navigating Acumen's Alzheimer's Risk And Reward

Oct 3, 2023, 11:03 AM EDT - 1 year ago

Navigating Acumen's Alzheimer's Risk And Reward


vaselineguy
vaselineguy Jun. 24 at 3:11 AM
$ABOS still here
0 · Reply
JarvisFlow
JarvisFlow Jun. 17 at 12:00 PM
Citigroup has updated their rating for Acumen Pharmaceuticals ( $ABOS ) to Buy with a price target of 4.
0 · Reply
DougieFreshPicks
DougieFreshPicks Jun. 9 at 11:39 PM
$ABOS on the list 👍
0 · Reply
somaopp
somaopp Jun. 8 at 5:53 PM
$ABOS Looks somewhat promising but its a one trick pony..
0 · Reply
Bio_Oko
Bio_Oko May. 23 at 1:59 PM
$AVXL Just added to my Video Channel and patreon.com/Bio_Oko blog a short video/presentation on $ABOS . Contains references to ANAVEX . https://youtu.be/kvy9tUfyqBc
0 · Reply
vaselineguy
vaselineguy Apr. 11 at 8:26 PM
$ABOS here we gooo
1 · Reply
vaselineguy
vaselineguy Apr. 4 at 4:23 PM
$ABOS grabbed
0 · Reply
DonCorleone77
DonCorleone77 Apr. 2 at 11:29 AM
$ABOS Acumen presented results from pTau217 assay in Phase 2 ALTITUDE-AD trial Acumen Pharmaceuticals presented extended results from its validated research-use plasma pTau217 assay to screen potential participants in the ongoing Phase 2 ALTITUDE-AD clinical trial of sabirnetug, showing this strategy has performed as intended. The company presented the results during an oral presentation at the International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders, AD/PD, in Vienna, Austria, from April 1-5, 2025, and will deliver an encore presentation at the American Academy of Neurology. AAN, Annual Meeting in San Diego, Calif., from April 5-9, 2025. Acumen is also presenting posters on methods of interrogating the binding of AbetaOs to a model of human neurons, methods to advance Abeta selectivity measurements and early effects of sabirnetug on synaptic biomarkers in AD.
1 · Reply
ElysiumAdvisors
ElysiumAdvisors Mar. 31 at 3:55 PM
$ABOS Some math here: Net cash of $200M, market cap at $65M. Assuming half 2027 cash burn rate and news of the phase 2 second half of 2026 that means that the current market expectations is not only that 100% the study fails but also that they spend over $140M. Market could be right, but I still think we get a move to the upside on repricing of drug % probability of success.
1 · Reply
JarvisFlow
JarvisFlow Mar. 28 at 1:37 PM
UBS updates rating for Acumen Pharmaceuticals ( $ABOS ) to Buy, target set at 6 → 4.
0 · Reply
JarvisFlow
JarvisFlow Mar. 28 at 1:00 PM
HC Wainwright & Co. has adjusted their stance on Acumen Pharmaceuticals ( $ABOS ), setting the rating to Buy with a target price of 15 → 11.
1 · Reply
d_risk
d_risk Mar. 28 at 3:11 AM
$ABOS - Acumen Pharmaceuticals Inc. Common Stock - 10K - Updated Risk Factors ABOS's 2025 10-K Risk Factors reveal heightened financial strain with doubled net losses, increased R&D focus on sabirnetug, regulatory and market uncertainties, and intensified competition. New risks include geopolitical tensions, evolving regulations, and cybersecurity threats, all impacting capital access and operational stability. #FinancialStrain #CybersecurityThreats #GeopoliticalRisks #RegulatoryUncertainty #R&DFocus 🟢 Added 🟠 Removed https://d-risk.ai/ABOS/10-K/2025-03-27
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SusQSmallMouth
SusQSmallMouth Mar. 27 at 6:26 PM
$ABOS Not sure what else you could expect here. Management seems competent and are putting together a large trial (540 participants) ahead of projections with cash until phase 2 readout. My guess is, if data is good, they will either be able to raise money at a substantially higher price from here or will secure a parter for phase 3. Only surprise I could see is them partnering before readout but probably not likely nor financially beneficial. It's a wait game which isn't good in this market but could provide great opportunities to add if you are feeling good about the science. I don't know much about the science but the opportunity is massive which is why I have a small position and will patiently wait.
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TradeHawk
TradeHawk Mar. 27 at 6:14 PM
$ABOS Acumen Pharmaceuticals review article out in The Journal of Prevention of Alzheimer's Disease: Biofluid biomarker changes following treatment with sabirnetug (ACU193) in INTERCEPT-AD, a phase 1 trial in early Alzheimer's disease. https://www.sciencedirect.com/science/article/pii/S2274580725000263
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redistributeW
redistributeW Mar. 27 at 12:05 PM
$ABOS 100 million loss for the year and will have no results until late 26? Nice
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mikesterz7
mikesterz7 Mar. 27 at 11:54 AM
$ABOS Acumen Pharmaceuticals has reported its financial results for 2024 and provided key business updates. The company completed enrollment in its Phase 2 ALTITUDE-AD study, investigating sabirnetug for early Alzheimer's disease, with topline results expected in late 2026. Key financial highlights include cash position of $231.5 million as of December 31, 2024, expected to fund operations into first half of 2027. The company reported increased R&D expenses of $93.8 million (vs $42.3 million in 2023) and G&A expenses of $20.2 million (vs $18.8 million in 2023). Net loss widened to $102.3 million from $52.4 million in 2023. Recent developments include positive Phase 1 results for a subcutaneous sabirnetug formulation and the publication of INTERCEPT-AD study results showing the drug was well-tolerated with dose-dependent target engagement.
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Rage_Against_The_Machine
Rage_Against_The_Machine Mar. 27 at 11:28 AM
$ABOS completes Phase 2 enrollment for Alzheimer's drug sabirnetug with 542 patients. Cash runway extends to H1 2027 ($231.5M). Subcutaneous formulation shows promise. Now the long wait begins - topline data expected late 2026. High stakes binary play with R&D spend hitting $93.8M in 2024. https://www.sec.gov/Archives/edgar/data/1576885/000157688525000044/abos-20250327.htm
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RAPIDTRADX
RAPIDTRADX Mar. 27 at 11:16 AM
$ABOS KEEP👀ON
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DonCorleone77
DonCorleone77 Mar. 27 at 11:12 AM
$ABOS Acumen expects topline results from ALTITUDE-AD in late 2026 The Company expects topline results from ALTITUDE-AD, a Phase 2 study to investigate sabirnetug for the treatment of early Alzheimer's disease, in late 2026.
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DonCorleone77
DonCorleone77 Mar. 27 at 11:10 AM
$ABOS Acumen sees cash runway into 1H27 As of Dec. 31, 2024, cash, cash equivalents and marketable securities totaled $231.5 million, compared to cash, cash equivalents and marketable securities of $306.1 million as of December 31, 2023. The decrease in cash is related to funding ongoing operations. Cash is expected to support current clinical and operational activities into the first half of 2027.
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DonCorleone77
DonCorleone77 Mar. 27 at 11:10 AM
$ABOS Acumen reports FY24 EPS ($1.71), consensus ($1.32) "I am exceptionally proud of the considerable progress our team has made this past year in advancing the clinical development of sabirnetug, our next generation treatment for early Alzheimer's disease. We completed enrollment in our 540-participant Phase 2 study, ALTITUDE-AD, earlier than originally anticipated and expect topline results in late 2026. We also recently announced Phase 1 topline results for a subcutaneous option of sabirnetug, that support further development of this dosing option for increased patient convenience," said Daniel O'Connell, CEO. "Looking ahead, our team remains focused on the transformative opportunity to redefine the standard of care in early Alzheimer's disease. Through disciplined execution, continuous innovation and sabirnetug's high selectivity for toxic amyloid beta oligomers, we believe we are well-positioned to deliver a differentiated treatment option for patients."
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mikesterz7
mikesterz7 Mar. 27 at 10:58 AM
$ABOS Get ready
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