Market Cap 122.95M
Revenue (ttm) 0.00
Net Income (ttm) -39.72M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 107,600
Avg Vol 33,818
Day's Range N/A - N/A
Shares Out 8.97M
Stochastic %K 82%
Beta -0.23
Analysts Strong Sell
Price Target $35.50

Company Profile

ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS, which enables drug discovery through a combination of protein biology, physics, and supercomputing. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer's disease; PMN267 for the treatment of amyotrophi...

Industry: Biotechnology
Sector: Healthcare
Phone: 416 847 6898
Address:
1920 Yonge Street, Suite 200, Toronto, Canada
GoforProMIS
GoforProMIS Jul. 8 at 12:29 PM
$PMN are we ready to take off? Even if it’s early to speculate might this is a first sign with Roth Capital BUY initiation!
1 · Reply
Q8ha
Q8ha Jul. 8 at 11:39 AM
0 · Reply
GoforProMIS
GoforProMIS Jul. 8 at 10:52 AM
$PMN ProMIS has a Scientific Differentiation in Modern Diagnostics: The study utilizes blood-based biomarkers, which are now available as a more cost-effective alternative to expensive PET scans for screening and disease monitoring. This is particularly relevant given that traditional A/T/N imaging methods cost thousands of 💵. The blinded interim analysis could provide early indications of target engagement, even though it presents aggregated data across all participants without revealing treatment groups. Implications for the safety profile ARIA risk assessment: A primary objective is to evaluate whether PMN310, as a non-plaque binder, carries a reduced risk of ARIA (Amyloid-Related Imaging Abnormalities) compared to other amyloid-targeting antibodies. The study is designed to provide 95% confidence for the detection of ARIA.
0 · Reply
Fruchtworg
Fruchtworg Jul. 7 at 7:48 PM
$PMN gaining traction with expected news regarding their trials 🔥 $IBRX $POET soon to follow imho 👀 as always DYOR and always good to use -> 🧠
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 7:45 PM
$PMN Conclusion The biomarker data provide scientific evidence for ProMIS’s innovative concept: the selective elimination of toxic oligomers without affecting plaque formation. They are crucial for: • Validating target engagement • Optimizing dosage  • Demonstrating a potentially improved safety profile • Strategically positioning the therapy against approved treatments that carry black-box warnings for ARIA => Pipeline Expansion Applicability to other programs: Biomarker insights gained from PMN310 could also inform the development of other candidates, such as PMN267 (ALS) and PMN442 (MSA/Parkinson), as all of them are based on the selective recognition of toxic protein forms
0 · Reply
ProfessorCole
ProfessorCole Jul. 7 at 7:33 PM
$NSYS $PMN $CLRO matches
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 4:32 PM
$PMN waiting for breakout
0 · Reply
Towjoe
Towjoe Jul. 7 at 4:16 PM
$PMN in the meantime China cured type 1, 2 diabetes. Japanese can grow us a new set of teeth. Just saying.
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 4:05 PM
$PMN $PMN finally closed the Gap at $13,71 watch what happens now - big boys playing yo-yo 🪀 till it takes off
0 · Reply
Kgra
Kgra Jul. 7 at 4:03 PM
$PMN I’ll take .5 a day
0 · Reply
Latest News on PMN
ProMIS Neurosciences initiated with a Buy at Roth Capital

2026-07-08T09:25:08.000Z - 7 hours ago

ProMIS Neurosciences initiated with a Buy at Roth Capital


ProMIS Neurosciences initiated with a Buy at Roth Capital

2026-07-07T20:10:17.000Z - 20 hours ago

ProMIS Neurosciences initiated with a Buy at Roth Capital


ProMIS Neurosciences Transcript: AGM 2026

May 20, 2026, 10:30 AM EDT - 7 weeks ago

ProMIS Neurosciences Transcript: AGM 2026


ProMIS Neurosciences initiated with a Buy at Brookline

2026-05-20T10:26:02.000Z - 7 weeks ago

ProMIS Neurosciences initiated with a Buy at Brookline


ProMIS Neurosciences Earnings release: Q1 2026

May 12, 2026, 7:00 AM EDT - 2 months ago

ProMIS Neurosciences Earnings release: Q1 2026


ProMIS Neurosciences Quarterly report: Q1 2026

May 12, 2026, 7:00 AM EDT - 2 months ago

ProMIS Neurosciences Quarterly report: Q1 2026


ProMIS Neurosciences Slides: Investor presentation

May 11, 2026, 7:00 AM EDT - 2 months ago

ProMIS Neurosciences Slides: Investor presentation


ProMIS Neurosciences Proxy statement: Proxy filing

Apr 9, 2026, 8:00 AM EDT - 3 months ago

ProMIS Neurosciences Proxy statement: Proxy filing


ProMIS Neurosciences Proxy statement: Proxy filing

Apr 9, 2026, 8:00 AM EDT - 3 months ago

ProMIS Neurosciences Proxy statement: Proxy filing


ProMIS Neurosciences files $200M mixed securities shelf

2026-03-25T21:25:26.000Z - 3 months ago

ProMIS Neurosciences files $200M mixed securities shelf


ProMIS Neurosciences Annual report: Q4 2025

Mar 25, 2026, 8:00 AM EDT - 3 months ago

ProMIS Neurosciences Annual report: Q4 2025


ProMIS Neurosciences Earnings release: Q4 2025

Mar 25, 2026, 8:00 AM EDT - 3 months ago

ProMIS Neurosciences Earnings release: Q4 2025


ProMIS Neurosciences Registration statement: Registration filing

Mar 25, 2026, 8:00 AM EDT - 3 months ago

ProMIS Neurosciences Registration statement: Registration filing


ProMIS Neurosciences Registration statement: Registration Filing

Mar 18, 2026, 8:00 AM EDT - 4 months ago

ProMIS Neurosciences Registration statement: Registration Filing


Promis Neurosciences Inc trading resumes

2026-01-30T14:40:46.000Z - 5 months ago

Promis Neurosciences Inc trading resumes


ProMIS Neurosciences exceeds target enrollment in PRECISE-AD

2025-12-18T12:36:07.000Z - 7 months ago

ProMIS Neurosciences exceeds target enrollment in PRECISE-AD


ProMIS Neurosciences announces publication highlighting PMN310

2025-12-10T12:45:11.000Z - 7 months ago

ProMIS Neurosciences announces publication highlighting PMN310


Promis Neurosciences Inc trading halted, news pending

2025-11-27T00:50:21.000Z - 7 months ago

Promis Neurosciences Inc trading halted, news pending


ProMIS Neurosciences announces 1-for-20 reverse stock split

2025-11-24T13:25:21.000Z - 8 months ago

ProMIS Neurosciences announces 1-for-20 reverse stock split


ProMIS Neurosciences Announces Reverse Stock Split

Nov 24, 2025, 8:00 AM EST - 8 months ago

ProMIS Neurosciences Announces Reverse Stock Split


ProMIS Neurosciences reports Q3 EPS (24c) vs 31c last year

2025-11-12T12:22:19.000Z - 8 months ago

ProMIS Neurosciences reports Q3 EPS (24c) vs 31c last year


ProMIS Neurosciences Earnings release: Q3 2025

Nov 12, 2025, 7:00 AM EST - 8 months ago

ProMIS Neurosciences Earnings release: Q3 2025


ProMIS Neurosciences Quarterly report: Q3 2025

Nov 12, 2025, 7:00 AM EST - 8 months ago

ProMIS Neurosciences Quarterly report: Q3 2025


ProMIS Neurosciences Proxy statement: Proxy Filing

Oct 3, 2025, 8:00 AM EDT - 9 months ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Oct 3, 2025, 8:00 AM EDT - 9 months ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Sep 23, 2025, 8:00 AM EDT - 10 months ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Registration statement: Registration Filing

Sep 4, 2025, 8:00 AM EDT - 10 months ago

ProMIS Neurosciences Registration statement: Registration Filing


ProMIS Neurosciences files $50M mixed securities shelf

2025-08-13T20:40:25.000Z - 11 months ago

ProMIS Neurosciences files $50M mixed securities shelf


ProMIS Neurosciences Registration statement: Registration Filing

Aug 13, 2025, 8:00 AM EDT - 11 months ago

ProMIS Neurosciences Registration statement: Registration Filing


ProMIS Neurosciences Earnings release: Q2 2025

Aug 13, 2025, 7:00 AM EDT - 11 months ago

ProMIS Neurosciences Earnings release: Q2 2025


ProMIS Neurosciences Quarterly report: Q2 2025

Aug 13, 2025, 7:00 AM EDT - 11 months ago

ProMIS Neurosciences Quarterly report: Q2 2025


ProMIS Neurosciences Announces Private Placement Financing

Jul 28, 2025, 7:00 AM EDT - 1 year ago

ProMIS Neurosciences Announces Private Placement Financing


ProMIS Neurosciences Quarterly report: Q1 2025

May 12, 2025, 7:30 AM EDT - 1 year ago

ProMIS Neurosciences Quarterly report: Q1 2025


ProMIS Neurosciences Earnings release: Q1 2025

May 12, 2025, 7:30 AM EDT - 1 year ago

ProMIS Neurosciences Earnings release: Q1 2025


ProMIS Neurosciences Proxy statement: Proxy Filing

Apr 29, 2025, 8:00 AM EDT - 1 year ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Apr 29, 2025, 8:00 AM EDT - 1 year ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Annual report: Q4 2024

Mar 31, 2025, 7:00 AM EDT - 1 year ago

ProMIS Neurosciences Annual report: Q4 2024


ProMIS Neurosciences Earnings release: Q4 2024

Mar 31, 2025, 7:00 AM EDT - 1 year ago

ProMIS Neurosciences Earnings release: Q4 2024


ProMIS Neurosciences Issues Letter to Shareholders

Jan 13, 2025, 10:30 AM EST - 1 year ago

ProMIS Neurosciences Issues Letter to Shareholders


ProMIS Neurosciences Quarterly report: Q3 2024

Nov 13, 2024, 6:00 PM EST - 1 year ago

ProMIS Neurosciences Quarterly report: Q3 2024


ProMIS Neurosciences Earnings release: Q3 2024

Nov 13, 2024, 6:00 PM EST - 1 year ago

ProMIS Neurosciences Earnings release: Q3 2024


ProMIS Neurosciences Proxy statement: Proxy Filing

Sep 9, 2024, 8:00 AM EDT - 1 year ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Sep 9, 2024, 8:00 AM EDT - 1 year ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Aug 29, 2024, 8:00 AM EDT - 2 years ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Quarterly report: Q2 2024

Aug 7, 2024, 6:00 PM EDT - 2 years ago

ProMIS Neurosciences Quarterly report: Q2 2024


ProMIS Neurosciences Earnings release: Q2 2024

Aug 7, 2024, 6:00 PM EDT - 2 years ago

ProMIS Neurosciences Earnings release: Q2 2024


ProMIS Neurosciences Quarterly report: Q1 2024

May 13, 2024, 6:00 PM EDT - 2 years ago

ProMIS Neurosciences Quarterly report: Q1 2024


ProMIS Neurosciences Earnings release: Q1 2024

May 13, 2024, 6:00 PM EDT - 2 years ago

ProMIS Neurosciences Earnings release: Q1 2024


ProMIS Neurosciences Proxy statement: Proxy Filing

Apr 25, 2024, 8:00 AM EDT - 2 years ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Proxy statement: Proxy Filing

Apr 25, 2024, 8:00 AM EDT - 2 years ago

ProMIS Neurosciences Proxy statement: Proxy Filing


ProMIS Neurosciences Earnings release: Q4 2023

Mar 31, 2024, 6:00 PM EDT - 2 years ago

ProMIS Neurosciences Earnings release: Q4 2023


ProMIS Neurosciences, Inc. Announces Leadership Transition

Jan 3, 2024, 7:00 AM EST - 2 years ago

ProMIS Neurosciences, Inc. Announces Leadership Transition


ProMIS Neurosciences Quarterly report: Q3 2023

Nov 13, 2023, 6:00 PM EST - 2 years ago

ProMIS Neurosciences Quarterly report: Q3 2023


ProMIS Neurosciences Earnings release: Q3 2023

Nov 13, 2023, 6:00 PM EST - 2 years ago

ProMIS Neurosciences Earnings release: Q3 2023


GoforProMIS
GoforProMIS Jul. 8 at 12:29 PM
$PMN are we ready to take off? Even if it’s early to speculate might this is a first sign with Roth Capital BUY initiation!
1 · Reply
Q8ha
Q8ha Jul. 8 at 11:39 AM
0 · Reply
GoforProMIS
GoforProMIS Jul. 8 at 10:52 AM
$PMN ProMIS has a Scientific Differentiation in Modern Diagnostics: The study utilizes blood-based biomarkers, which are now available as a more cost-effective alternative to expensive PET scans for screening and disease monitoring. This is particularly relevant given that traditional A/T/N imaging methods cost thousands of 💵. The blinded interim analysis could provide early indications of target engagement, even though it presents aggregated data across all participants without revealing treatment groups. Implications for the safety profile ARIA risk assessment: A primary objective is to evaluate whether PMN310, as a non-plaque binder, carries a reduced risk of ARIA (Amyloid-Related Imaging Abnormalities) compared to other amyloid-targeting antibodies. The study is designed to provide 95% confidence for the detection of ARIA.
0 · Reply
Fruchtworg
Fruchtworg Jul. 7 at 7:48 PM
$PMN gaining traction with expected news regarding their trials 🔥 $IBRX $POET soon to follow imho 👀 as always DYOR and always good to use -> 🧠
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 7:45 PM
$PMN Conclusion The biomarker data provide scientific evidence for ProMIS’s innovative concept: the selective elimination of toxic oligomers without affecting plaque formation. They are crucial for: • Validating target engagement • Optimizing dosage  • Demonstrating a potentially improved safety profile • Strategically positioning the therapy against approved treatments that carry black-box warnings for ARIA => Pipeline Expansion Applicability to other programs: Biomarker insights gained from PMN310 could also inform the development of other candidates, such as PMN267 (ALS) and PMN442 (MSA/Parkinson), as all of them are based on the selective recognition of toxic protein forms
0 · Reply
ProfessorCole
ProfessorCole Jul. 7 at 7:33 PM
$NSYS $PMN $CLRO matches
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 4:32 PM
$PMN waiting for breakout
0 · Reply
Towjoe
Towjoe Jul. 7 at 4:16 PM
$PMN in the meantime China cured type 1, 2 diabetes. Japanese can grow us a new set of teeth. Just saying.
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 4:05 PM
$PMN $PMN finally closed the Gap at $13,71 watch what happens now - big boys playing yo-yo 🪀 till it takes off
0 · Reply
Kgra
Kgra Jul. 7 at 4:03 PM
$PMN I’ll take .5 a day
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 3:26 PM
Full Alzheimer Disease Analyze: If $PMN can use its blinded data to demonstrate that it can achieve the same therapeutic effect as Leqembi or Kisunla without the associated side effects, the stock is poised for extremely dynamic catch-up growth relative to these multi-billion-dollar corporations. $BIIB Drug: Leqembi®️ (lecanemab) FDA-approved. Issue: Slows cognitive decline by approximately 27% but carries the well-known, high ARIA safety risk (approx. 13% incidence of brain swelling in studies). $LLY Kisunla FDA-approved. Issue: Slows decline by up to 35% but has the highest ARIA rate on the market due to its biological mechanism. Phase 3 drugs: $RHHBY Trontinemab Status is a highly sophisticated antibody utilizing "brain shuttle" technology. $AXSM Auvelity FDA expanded approval to include the treatment of agitation associated with AD. $ AVXL Blarcamesine Phase 3 completed. Not an antibody, but an oral tablet. A completely different biological pathway compared to $PMN!
0 · Reply
GoforProMIS
GoforProMIS Jul. 7 at 11:27 AM
$PMN If I summarize all available information: 🟢 Fast Track → scientifically and regulatorily plausible. 🟢 Peer review → mechanism scientifically supported. 🟢 DSMB/safety profile → no obvious safety issues so far. 🟢 Over-recruitment → indicates successful study implementation and interest. 🟢 Platform medicine for 1. Parkinson’s Disease & Multiple System Atrophy (MSA) 2. ALS (Amyotrophic Lateral Sclerosis) & Frontotemporal Dementia (FTD) 3. Schizophrenia & Huntington’s disease (research stage) and ALL based on PM310!
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 7:23 PM
$PMN ProMIS will be skyrocketing when it has been mathematically demonstrated that PMN310 could be by a wide margin the safest ALS drug in the world. This would effectively eliminate the risk of brain swelling.if 144 patients (108 on active drug / 36 on placebo) are better than the historical benchmark $BIIB or $LLY In the pivotal trials for Leqembi (lecanemab) and Kisunla (donanemab), the average rate of ARIA-E (swelling) ranged from approximately 15% to 24%. In a typical Alzheimer’s population not receiving the drug (placebo group), the natural ARIA rate is around 1% to 2% (spontaneous microhemorrhages). This yields the expected ARIA incidence for the PRECISE-AD trial, assuming PMN310 performs no better than the competition: 36 placebo patients × 1.5% = ~0.5 cases; 108 active-drug patients × 18% (competitor average) = ~19.5 cases. Expected total number of ARIA cases in a blinded analysis: approx. 20 cases.
1 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 7:08 PM
What to look for in the News: DSMB (Data and Safety Monitoring Board) "DSMB recommended to continue the study without modifications." This indicates that there were no unforeseen deaths or serious risks. Statistically significant or p-value – Look for: A p-value of p < 0.05 regarding the biomarkers indicates that the reduction was not due to chance. Quick screen check (30 seconds): Open the document. Ctrl + F -> enter "ARIA". Is the number of cases close to zero? -> Positive. Ctrl + F -> enter "p-Tau217". Does it mention a "decrease" or "reduction"? -> Positive. If both conditions are met, the EpiSelect platform has delivered the expected mathematical results. And it will exponentially rocket which you never have seen before! Good Luck getting in $PMN after this news is out 😂🤣😂
0 · Reply
Luckyizme
Luckyizme Jul. 6 at 7:04 PM
$PMN Nice gains
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 6:30 PM
$PMN Scenario 2: The mathematical safety model: Total participants: 144 patients (108 on active drug / 36 on placebo). The historical benchmark (Biogen / Eli Lilly): In the pivotal trials for Leqembi (lecanemab) and Kisunla (donanemab), the average rate of ARIA-E (swelling) ranged from approximately 15% to 24%. In a typical Alzheimer’s population not receiving the drug (placebo group), the natural ARIA rate is around 1% to 2% (spontaneous microhemorrhages). This yields the expected ARIA incidence for the PRECISE-AD trial, assuming PMN310 performs no better than the competition: 36 placebo patients × 1.5% = ~0.5 cases; 108 active-drug patients × 18% (competitor average) = ~19.5 cases. Expected total number of ARIA cases in a blinded analysis: approx. 20 cases. The market reaction: The stock is skyrocketing. It has been mathematically demonstrated that PMN310 could be by a wide margin the safest ALS drug in the world. This would effectively eliminate the risk of brain swelling.
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 6:24 PM
$PMN Scenario 1: High-dose speculation: Since the 108 patients receiving the drug are divided into three dosage groups (low, medium, high)—and low doses typically show little effect—this strong overall figure implies that the high-dose group (1400 mg) must have experienced a phenomenal drop in the biomarker (perhaps -0.7 pg/ml). Statistical certainty: With this interim mathematical result, the statistical probability of success (PoS) for achieving the primary endpoint upon unblinding in early 2027 jumps suddenly from perhaps 25% to over 80%. It is precisely this advance mathematical certainty that drives institutional investors to aggressively buy up the stock immediately following the interim analysis, rather than waiting for the unblinding in 2027.
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 6:24 PM
$PMN Scenarios how the stock will take off based on some calculation: When analysts arrive at an isolated drug effect figure of -0.4 pg/ml, it triggers a chain reaction on Wall Street: Comparison with blockbusters: For context, Biogen/Eisai’s already approved antibody Leqembi lowers p-Tau217 levels by approximately -0.3 to -0.35 pg/ml over similar timeframes. A calculated value of -0.4 pg/ml would imply that PMN310 is potentially more effective than the current market leader.
0 · Reply
Fruchtworg
Fruchtworg Jul. 6 at 5:45 PM
$PMN meant tuesday, wednesday or thursday, lol :)
0 · Reply
Fruchtworg
Fruchtworg Jul. 6 at 5:44 PM
$PMN so .. i guess we might get news next week or the week after, probably tuesday, wednesday or sunday? that's early Q3 for , and i hope for super low %-Aria
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 4:21 PM
$PMN bids stacking up see you at $15
0 · Reply
GoforProMIS
GoforProMIS Jul. 6 at 2:22 PM
$PMN If you recognise no Gap is pre and after hour which means this stock is in big investors hand and will go exponential soon. Anybody who sells or plays selling and buying back cheaper will regret. Keep your eyes on the stars, your feet on ground and your fingers relaxed!
0 · Reply