Jul. 25 at 12:24 PM
Unicycive Therapeutics (Nasdaq:
$UNCY) announced the publication of oxylanthanum carbonate (OLC) pivotal trial data in Clinical Journal of the American Society of Nephrology, noting that OLC was well-tolerated and enabled serum phosphate control in more than 90% of patients, as well as providing the benefit of low pill burden.
This publication marks a milestone for the company as it continues to work with the FDA to address outstanding manufacturing questions and move toward bringing OLC to patients with chronic kidney disease who are on dialysis.
Unicycive Therapeutics is a B2i Digital Featured Company. View their comprehensive profile at https://b2idigital.com/unicycive.
Among the highlights of today’s announcement are:
-More than 90% of patients taking OLC achieved effective phosphate control.
- Two-thirds of patients required three or fewer OLC tablets per day to achieve target serum phosphate levels, with most requiring no more than one tablet with each meal.
- OLC was well tolerated in CKD patients on dialysis, with only 4% of patients discontinuing treatment due to treatment-related adverse events.
- The most common treatment-related adverse events (all less than 10%) were gastrointestinal.
See the full press release at https://ir.unicycive.com/news/detail/107/unicycive-therapeutics-announces-the-publication-of.
Unicycive Therapeutics is a clinical-stage biotechnology company developing innovative therapies for kidney diseases. The company’s lead investigational treatment, oxylanthanum carbonate, is a novel phosphate-binding agent for treating hyperphosphatemia in patients with chronic kidney disease who are on dialysis. Its second program, UNI-494, targets conditions related to acute kidney injury and has received FDA orphan drug designation for preventing delayed graft function in kidney transplant patients.
Led by CEO Dr. Shalabh Gupta, MD and a seasoned executive team including CFO John Townsend, EVP Doug Jermasek, EVP Pramod Gupta, Dr. Atul Khare, Ph.D., M.B.A., and Dr. Guru Reddy, Unicycive is committed to addressing unmet needs in kidney disease treatment.
Learn more at Unicycive (https://unicycive.com/) and B2i Digital (https://b2idigital.com/).
Disclosure: David Shapiro, CEO of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted UNCY stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. This post is not intended to solicit the sale of UNCY or any security, and it is not intended to offer any opinion on UNCY as an investment. Conduct your own research and consult with your own professional advisors prior to making any investment decisions. See the complete Disclosure in the Risks and Disclosures section of https://b2idigital.com/disclaimer
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