Market Cap 887.22M
Revenue (ttm) 107.46M
Net Income (ttm) 105.90M
EPS (ttm) N/A
PE Ratio 22.37
Forward PE 17.66
Profit Margin 98.55%
Debt to Equity Ratio 0.00
Volume 436,100
Avg Vol 693,312
Day's Range N/A - N/A
Shares Out 51.49M
Stochastic %K 99%
Beta 0.17
Analysts Sell
Price Target $16.83

Company Profile

Theravance Biopharma, Inc., a biopharmaceutical company, develops and commercializes medicines in the United States. It offers YUPELRI, an once-daily, nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease (COPD); and Ampreloxetine an investigational, once-daily norepinephrine reuptake inhibitor, Which is in Phase 3 clinical trials for symptomatic neurogenic orthostatic hypotension (nOH) in patients with Multiple System Atrophy (MSA). It has a stra...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 808 6000
Address:
901 Gateway Boulevard, South San Francisco, United States
Night_Owl_Biotech
Night_Owl_Biotech Apr. 12 at 10:02 PM
Smaller cap (under $1B) commercial-stage biopharma M&A exit valuations as multiples of mgmt/BOD prepared revenue & gross margin forecasts. It's our experience comm'l-stage bios projected to do $1B in sales/year are acquired for 0.30 to 0.40X 10 year revenue forecasts. Generally speaking, and not all of the time but generally speaking, the larger the revenue forecast the higher the multiples. Comm'l-stage bios in this peer group are acquired for 0.15 to 0.25X 10 year revenue projections. Investors in the comm'l-stage bios below have revenue & gross margin forecasts consistent with those in this peer group (on the attachment) $ZVRA $TBPH $AQST $VALN $HRTX This is not investment advice. We're merely sharing our analysis.
4 · Reply
Itinerant
Itinerant Apr. 10 at 8:15 PM
$TBPH In my opinion, the probability of the company being sold is very high. The company has nothing in the pipeline to justify their overhead. The Board has had a "shareholder value committee" for some time and it has just been recharged. The sale is relatively easy by the nature of its assets and revenue. The company has a very nice $430 million deferred tax asset among other liquid assets. I calculate the take out price is likely at least $30, but could be more. The continuing operational value, even with the cost reductions, is about $22. The Board has no choice but to sell the company. Price action has been excellent. JMO
1 · Reply
voorbie
voorbie Apr. 8 at 7:21 PM
$TBPH TBPH is now trading at an MCAP of 850M, 400M of which is cash which implies an enterprise value of 450M. They have max possible remaining royalties of $100M on Trelegy and are making $100M/yr from Yupelri royalties in the US (licensing deal with Viatris). Yupelri was approved in China in late 2025 so I’m guessing you could double US sales and assume annual royalties on Yupelri of 200M. Both Trelegy and Yupelri are pure profit - no operating costs - so $200M licensing revenue for Yupelri should be close to $200M profit/year. Hence, the licensing revenue from Yupelri alone is much more than enterprise value of 450M. Someone will buy them. It’s just a matter of who and for how much. I ran a quick net present value on Yupelri profits (excluding remaining 100M for Trelegy) for the next 6 years at a discount rate of 15%, assuming revenue growth to $350M by year 6. Implied NPV is 800M. Add back cash and that’s 1.2B - 41% over the current MCAP, = price per share of $23.30.
1 · Reply
SuperGreenToday
SuperGreenToday Apr. 8 at 12:41 AM
$TBPH Share Price: $16.58 Contract Selected: Sep 18, 2026 $10 Calls Buy Zone: $3.82 – $4.73 Target Zone: $6.72 – $8.21 Potential Upside: 66% ROI Time to Expiration: 163 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Itinerant
Itinerant Apr. 7 at 8:03 PM
$TBPH My theory is that the analysts have run the numbers on the value of the planned operating cost reductions and the potential takeout value and have told their best clients. The institutions are now buying. Immediate target = $22
0 · Reply
Itinerant
Itinerant Apr. 7 at 7:59 PM
$TBPH Breakout: target $22.
0 · Reply
Itinerant
Itinerant Apr. 7 at 6:13 PM
$TBPH $16.50 resistance
0 · Reply
Itinerant
Itinerant Apr. 7 at 4:48 PM
$TBPH Will she break the $15 level? I think so, but first I suppose there will be some resistance. I see $22 coming.
0 · Reply
zerodayrounder
zerodayrounder Apr. 7 at 12:29 AM
my $TBPH #s were a bit off .. i didn't fact check Gemini. Call it $1.8 billion total Theravance received. Trelegy royalty rate 6-8% on $3.5 billion annual sales $SPRO then is worth what to $GSK or $RPRX ? 2.5 billion peak sales from 2031-2041 -- 12% royalties over $1 billion -- minus whatever SPRO pays Meiji. https://gemini.google.com/share/273ee80740fa
1 · Reply
zerodayrounder
zerodayrounder Apr. 6 at 11:53 PM
$GSK would essentially be buying back the milestones and royalties it expects to owe $SPRO going out to 2041. If that number is $2-3 billion over the life of tebi -- perhaps spending 1/3rd of that amount today is worth it from a DCF perspective (and controlling a blockbuster drug) Similar to how GSK bought back the royalty stream it owed to $TBPH for Trelegy ... I think they paid $225 million in July 2025 for whatever royalties (the so-called "out years" in 2030/2031+) hadn't already been sold to $RPRX back in 2021
1 · Reply
Latest News on TBPH
Theravance Biopharma Plummets As Phase 3 Study Falls Short

Mar 3, 2026, 1:19 PM EST - 6 weeks ago

Theravance Biopharma Plummets As Phase 3 Study Falls Short


Night_Owl_Biotech
Night_Owl_Biotech Apr. 12 at 10:02 PM
Smaller cap (under $1B) commercial-stage biopharma M&A exit valuations as multiples of mgmt/BOD prepared revenue & gross margin forecasts. It's our experience comm'l-stage bios projected to do $1B in sales/year are acquired for 0.30 to 0.40X 10 year revenue forecasts. Generally speaking, and not all of the time but generally speaking, the larger the revenue forecast the higher the multiples. Comm'l-stage bios in this peer group are acquired for 0.15 to 0.25X 10 year revenue projections. Investors in the comm'l-stage bios below have revenue & gross margin forecasts consistent with those in this peer group (on the attachment) $ZVRA $TBPH $AQST $VALN $HRTX This is not investment advice. We're merely sharing our analysis.
4 · Reply
Itinerant
Itinerant Apr. 10 at 8:15 PM
$TBPH In my opinion, the probability of the company being sold is very high. The company has nothing in the pipeline to justify their overhead. The Board has had a "shareholder value committee" for some time and it has just been recharged. The sale is relatively easy by the nature of its assets and revenue. The company has a very nice $430 million deferred tax asset among other liquid assets. I calculate the take out price is likely at least $30, but could be more. The continuing operational value, even with the cost reductions, is about $22. The Board has no choice but to sell the company. Price action has been excellent. JMO
1 · Reply
voorbie
voorbie Apr. 8 at 7:21 PM
$TBPH TBPH is now trading at an MCAP of 850M, 400M of which is cash which implies an enterprise value of 450M. They have max possible remaining royalties of $100M on Trelegy and are making $100M/yr from Yupelri royalties in the US (licensing deal with Viatris). Yupelri was approved in China in late 2025 so I’m guessing you could double US sales and assume annual royalties on Yupelri of 200M. Both Trelegy and Yupelri are pure profit - no operating costs - so $200M licensing revenue for Yupelri should be close to $200M profit/year. Hence, the licensing revenue from Yupelri alone is much more than enterprise value of 450M. Someone will buy them. It’s just a matter of who and for how much. I ran a quick net present value on Yupelri profits (excluding remaining 100M for Trelegy) for the next 6 years at a discount rate of 15%, assuming revenue growth to $350M by year 6. Implied NPV is 800M. Add back cash and that’s 1.2B - 41% over the current MCAP, = price per share of $23.30.
1 · Reply
SuperGreenToday
SuperGreenToday Apr. 8 at 12:41 AM
$TBPH Share Price: $16.58 Contract Selected: Sep 18, 2026 $10 Calls Buy Zone: $3.82 – $4.73 Target Zone: $6.72 – $8.21 Potential Upside: 66% ROI Time to Expiration: 163 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Itinerant
Itinerant Apr. 7 at 8:03 PM
$TBPH My theory is that the analysts have run the numbers on the value of the planned operating cost reductions and the potential takeout value and have told their best clients. The institutions are now buying. Immediate target = $22
0 · Reply
Itinerant
Itinerant Apr. 7 at 7:59 PM
$TBPH Breakout: target $22.
0 · Reply
Itinerant
Itinerant Apr. 7 at 6:13 PM
$TBPH $16.50 resistance
0 · Reply
Itinerant
Itinerant Apr. 7 at 4:48 PM
$TBPH Will she break the $15 level? I think so, but first I suppose there will be some resistance. I see $22 coming.
0 · Reply
zerodayrounder
zerodayrounder Apr. 7 at 12:29 AM
my $TBPH #s were a bit off .. i didn't fact check Gemini. Call it $1.8 billion total Theravance received. Trelegy royalty rate 6-8% on $3.5 billion annual sales $SPRO then is worth what to $GSK or $RPRX ? 2.5 billion peak sales from 2031-2041 -- 12% royalties over $1 billion -- minus whatever SPRO pays Meiji. https://gemini.google.com/share/273ee80740fa
1 · Reply
zerodayrounder
zerodayrounder Apr. 6 at 11:53 PM
$GSK would essentially be buying back the milestones and royalties it expects to owe $SPRO going out to 2041. If that number is $2-3 billion over the life of tebi -- perhaps spending 1/3rd of that amount today is worth it from a DCF perspective (and controlling a blockbuster drug) Similar to how GSK bought back the royalty stream it owed to $TBPH for Trelegy ... I think they paid $225 million in July 2025 for whatever royalties (the so-called "out years" in 2030/2031+) hadn't already been sold to $RPRX back in 2021
1 · Reply
Itinerant
Itinerant Apr. 6 at 1:54 PM
$TBPH I calculate the buyout price for TBPH to be about $40 per share.
0 · Reply
BioTechHealthX
BioTechHealthX Apr. 2 at 8:28 AM
$CVM $KOD $TBPH $VSA $WINT From high-risk moonshots to late-stage clinical winners, these top 5 biotech stocks are capturing massive investor attention. Discover which companies are nearing breakthroughs, regulatory catalysts, and explosive upside potential before the crowd catches on. https://biotechhealthx.com/biotech-news/top-5-biotech-stocks-to-watch-now/
0 · Reply
zerodayrounder
zerodayrounder Mar. 26 at 1:10 PM
so $TBPH sold its Trelegy royalty rights to $RPRX for $1.1 billion in 2022 (and retained "late-stage" royalties and milestones from Royalty Pharma if certain sales targets hit). In July 2025, TBPH sold its remaining "late stage" royalties to $GSK for $225 million. The Trelegy patent is supposed to end around 2031 and is a blockbuster for GSK. At one point, GSK owned 27% of TBPH but never purchased it outright -- although there was speculation it would 15 years ago. TBPH had multiple other drugs etc and wasn't basically just a one-drug royalty/shell company that has ceased new drug development like $SPRO ... Perhaps $GSK will take $SPRO in-house to avoid royalties like it did to clean up Trelegy royalty stream still retained by TBPH. https://gemini.google.com/share/4b89dc8a9570
1 · Reply
erevnon
erevnon Mar. 23 at 3:20 PM
TD Cowen maintains Theravance Biopharma $TBPH at Hold and raises the price target from $13 to https://marketsblock.com/stock-upgrades-and-downgrades/
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Itinerant
Itinerant Mar. 12 at 4:52 PM
$TBPH I am bullish on today's earnings report, odd as that might seem. My logic is this. The key is the operational restructuring after the failed trial, their only trial. If one applies the operational plan to the actual operating numbers, and recognizes the costs of restructuring, then the fair value of the company is about $21 on a continuing basis (+50%). In addition, the Board committee for shareholder value has been recharged into prompt action. Translation: let's sell the company. Doing the math, I see a sale value of about $27 per share (+100%). Selling the company should not be difficult because the balance sheet is strong, and the time horizon on the COPD product remains durable. I believe this will be made clear in the earnings report. I too am awaiting some detailed numbers from the ER. However, the analysts have said little to nothing so far. Once they run the numbers after the ER, they will revise their outlook, and be pumping the sale value. JMO
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Estimize
Estimize Mar. 11 at 12:00 PM
Wall St is expecting -0.06 EPS for $TBPH Q1 [Reporting 05/13 AMC] http://www.estimize.com/intro/tbph?chart=historical&metric_name=eps&utm_c
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Itinerant
Itinerant Mar. 4 at 7:04 PM
$TBPH The company blew the trial. Ok, that costs $250 million in market cap. That happened in a nano second. However, the company has since announced a major overhead cut, and step up of strategic alternative consideration: i.e. sell the company. Yet, the market does not appear to have reacted to that news. The market cap is now under valued substantially on this news. I bought. JMO
1 · Reply
ZacksResearch
ZacksResearch Mar. 4 at 4:21 PM
$TBPH just got crushed — down 26% after a major clinical setback ⚠️ Theravance Biopharma’s phase III CYPRESS study of ampreloxetine missed key endpoints, and management is halting the program altogether. Late-stage failure + program shutdown is a brutal combo for sentiment. If you’re holding or watching, you’ll want the full breakdown. 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-teaser-35944&ADID=SYND_STOCKTWITS_TWEET_2_2878770_TEASER_35944
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ZacksResearch
ZacksResearch Mar. 4 at 3:21 PM
$TBPH plunges 26% after CYPRESS study failure! 🚨 The late-stage trial for ampreloxetine missed its primary endpoint, leading TBPH to wind down the program and consider strategic options, including a potential sale. Despite the setback, TBPH's shares have gained 43.6% over the past year. Full breakdown here 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-body-35943&ADID=SYND_STOCKTWITS_TWEET_2_2878770_BODY_35943
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OGTDeepWaters
OGTDeepWaters Mar. 4 at 1:57 AM
$TBPH Next time someone says hey invest in this biotech, think about the numbers first, and yes your welcome, perspective in investing is important.
0 · Reply
Tradebub
Tradebub Mar. 3 at 7:58 PM
$TBPH Much more downside. This company is a failure (with some cash).
0 · Reply