Nov. 13 at 9:12 PM
Raymond James🏁
$MAZE Outperform/
$48
$VRTX $UNCY $OTSKY
Raymond James said: The Maze Compass platform leverages genetic insights to discover novel therapies for genetically validated targets.
MAZE's lead wholly-owned assets target high unmet need chronic kidney disease (CKD) populations: MZE829, an oral APOL1 inhibitor in Phase 2 for APOL1-mediated kidney disease (AMKD), and MZE782, an oral SLC6A19 inhibitor entering Phase 2 in phenylketonuria (PKU) and CKD.
Both assets have best-in-class potential in attractive commercial indications and encouraging early mechanistic de-risking, in our view.
While shares have roughly doubled from the January 2025 IPO, we believe MAZE continues to offer a very compelling risk/ reward skew into key Phase 2 readouts for MZE829 and MZE782 beginning in 2026.