Market Cap 128.47M
Revenue (ttm) 60,000.00
Net Income (ttm) -55.48M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -92,466.67%
Debt to Equity Ratio 0.00
Volume 878,000
Avg Vol 686,276
Day's Range N/A - N/A
Shares Out 62.97M
Stochastic %K 25%
Beta -0.23
Analysts Strong Sell
Price Target $7.25

Company Profile

Connect Biopharma Holdings Limited operates as a clinical-stage biopharmaceutical company in the United States. It develops rademikibart, a human monoclonal IgG4 antibody directed against IL-4Ra in two Phase 2 trials for the treatment of acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). The company was founded in 2012 and is headquartered in San Diego, California.

Industry: Biotechnology
Sector: Healthcare
Phone: 877 245 2787
Address:
3580 Carmel Mountain Road, Suite 200, San Diego, United States
Teshuvahh
Teshuvahh Sep. 14 at 12:13 PM
$CNTB I find it mildly constructive if they release tomorrow and are confident enough to take results questions in realtime.
0 · Reply
Carnagex
Carnagex Sep. 14 at 12:03 PM
$CNTB agree.
1 · Reply
JohnFromLongRobust
JohnFromLongRobust Sep. 14 at 11:24 AM
$CNTB If they don’t release today or tomorrow i’ll be surprised
0 · Reply
raingang
raingang Sep. 14 at 6:22 AM
$CNTB must be released within few hours
0 · Reply
mulc
mulc Sep. 14 at 6:13 AM
$CNTB Must of this is inaccurate. 1. There is an actual 2024 exposure-response analysis saying rademikibart has an approximately 25-day half-life, used to support monthly dosing in atopic dermatitis. The peer-reviewed Phase 1 PK paper explicitly says rademikibart has nonlinear, target-mediated clearance, so its half-life is concentration-dependent; After a single 600-mg SC dose, rademikibart was detectable for a median of approximately 56 days in the Phase 1 study. 2: This mixes up three completely different quantities: dose administered ≠ drug amount remaining in body ≠ plasma concentration. And none of those is the same as steady state. 3: SC bioavailability - You cannot derive plasma concentration at Day 28 by simply dividing 600 mg in half. 4: The major asthma study wasn't a China trial. Most rademikibart FEV₁ improvement occurred during Week 1 and was sustained through Week 24. Also Seabreeze's primary endpoint is NOT FEV₁ at Day 28. Connect measures FEV₁ at Week 1.
3 · Reply
GoImugene
GoImugene Sep. 14 at 3:47 AM
$CNTB half life of Rademikibart is 25 days. So the blood level of the dosage of 600mg SubQ at the 28 day period should be close to a 300 mg steady state level. Initial improvements have been rapid for the treatment arm in the China trial, but the SOC arm tends to ketch up somewhat at 28 day mark making stat Sig very close to p<0.05. It will be close. The Iseparate IV push trial will be easier to predict the outcome, which I believe will be stat sig in the future.
1 · Reply
GoImugene
GoImugene Sep. 14 at 3:22 AM
$CNTB is the September readout for SubQ route? Yes. For 2 minute IV push? No
0 · Reply
Teshuvahh
Teshuvahh Sep. 13 at 8:44 PM
$CNTB been waiting for this moment for so long…
0 · Reply
Carnagex
Carnagex Sep. 13 at 2:24 PM
$CNTB when preparing for a major presentation at a conference it takes time to produce the slides and prepare for the presentation. I believe that scheduling the HC Wainwright fireside chat on September 3 was done from a position of knowledge of the data. The presentation at the conference was scheduled in advance, but not the fireside chat. That was announced on September 3. Major presentations take 2 to 3 weeks to put together and I believe it would be lethal to the company to schedule a major financial fireside chat, not knowing the data or having ugly data. To schedule that fireside chat without knowing your data would be a seriously unusual and reckless move by the CEO. I put heavy weight on the fact that they have some data from one of the two trials or both that is positive.
2 · Reply
DMaulST
DMaulST Sep. 12 at 5:46 PM
2 · Reply
Latest News on CNTB
Connect Biopharma Holdings Earnings release: Q2 2026

Aug 12, 2026, 4:00 PM EDT - 4 weeks ago

Connect Biopharma Holdings Earnings release: Q2 2026


Connect Biopharma Holdings Quarterly report: Q2 2026

Aug 12, 2026, 4:00 PM EDT - 4 weeks ago

Connect Biopharma Holdings Quarterly report: Q2 2026


Connect Biopharma Holdings Slides: Corporate presentation

Jul 14, 2026, 9:00 AM EDT - 2 months ago

Connect Biopharma Holdings Slides: Corporate presentation


Connect Biopharma initiated with an Outperform at Oppenheimer

2026-07-09T12:00:36.000Z - 2 months ago

Connect Biopharma initiated with an Outperform at Oppenheimer


Connect Biopharma initiated with an Overweight at Piper Sandler

2026-06-26T10:00:38.000Z - 2 months ago

Connect Biopharma initiated with an Overweight at Piper Sandler


Connect Biopharma initiated with a Buy at Canaccord

2026-05-26T09:25:05.000Z - 3 months ago

Connect Biopharma initiated with a Buy at Canaccord


Connect Biopharma Holdings Slides: Corporate presentation

May 14, 2026, 7:00 AM EDT - 4 months ago

Connect Biopharma Holdings Slides: Corporate presentation


Connect Biopharma Holdings Earnings release: Q1 2026

May 12, 2026, 9:00 AM EDT - 4 months ago

Connect Biopharma Holdings Earnings release: Q1 2026


Connect Biopharma Holdings Quarterly report: Q1 2026

May 12, 2026, 9:00 AM EDT - 4 months ago

Connect Biopharma Holdings Quarterly report: Q1 2026


Connect Biopharma announces enrollment in Seabreeze STAT study

2026-04-23T13:29:20.000Z - 4 months ago

Connect Biopharma announces enrollment in Seabreeze STAT study


Connect Biopharma director buys $4.0M in common stock

2026-04-01T21:15:48.000Z - 5 months ago

Connect Biopharma director buys $4.0M in common stock


Connect Biopharma Holdings Annual report: Q4 2025

Mar 31, 2026, 4:00 PM EDT - 5 months ago

Connect Biopharma Holdings Annual report: Q4 2025


Connect Biopharma Holdings Earnings release: Q4 2025

Mar 31, 2026, 4:00 PM EDT - 5 months ago

Connect Biopharma Holdings Earnings release: Q4 2025


Connect Biopharma Holdings Transcript: Study result

Mar 30, 2026, 8:00 AM EDT - 5 months ago

Connect Biopharma Holdings Transcript: Study result


Connect Biopharma Holdings Press release: Study result

Mar 30, 2026, 8:00 AM EDT - 5 months ago

Connect Biopharma Holdings Press release: Study result


Connect Biopharma Holdings Slides: Study result

Mar 30, 2026, 8:00 AM EDT - 5 months ago

Connect Biopharma Holdings Slides: Study result


Connect Biopharma announces results from rademikibart study

2026-03-30T11:26:39.000Z - 5 months ago

Connect Biopharma announces results from rademikibart study


Connect Biopharma Holdings Slides: FY 2026

Mar 10, 2026, 8:00 AM EDT - 6 months ago

Connect Biopharma Holdings Slides: FY 2026


Connect Biopharma Holdings Slides: Corporate presentation

Jan 12, 2026, 7:00 AM EST - 8 months ago

Connect Biopharma Holdings Slides: Corporate presentation


Connect Biopharma initiated with a Buy at Lake Street

2025-12-01T13:45:55.000Z - 9 months ago

Connect Biopharma initiated with a Buy at Lake Street


Connect Biopharma Holdings Quarterly report: Q3 2025

Nov 12, 2025, 9:00 AM EST - 10 months ago

Connect Biopharma Holdings Quarterly report: Q3 2025


Connect Biopharma Holdings Earnings release: Q3 2025

Nov 12, 2025, 9:00 AM EST - 10 months ago

Connect Biopharma Holdings Earnings release: Q3 2025


Connect Biopharma Holdings Transcript: Status Update

Nov 3, 2025, 4:15 PM EST - 10 months ago

Connect Biopharma Holdings Transcript: Status Update


Connect Biopharma initiated with a Buy at BTIG

2025-10-31T10:10:32.000Z - 10 months ago

Connect Biopharma initiated with a Buy at BTIG


Connect Biopharma presents data on rademikibart at ERS Congress

2025-09-29T13:21:17.000Z - 11 months ago

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Connect Biopharma Holdings Quarterly report: H1 2025

Aug 13, 2025, 9:00 AM EDT - 1 year ago

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Connect Biopharma Holdings Earnings release: H1 2025

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Connect Biopharma Holdings Slides: Corporate Presentation

Jun 3, 2025, 7:00 AM EDT - 1 year ago

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Connect Biopharma Holdings Quarterly report: Q1 2025

May 15, 2025, 9:00 AM EDT - 1 year ago

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Connect Biopharma Holdings Earnings release: Q1 2025

May 15, 2025, 9:00 AM EDT - 1 year ago

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Connect Biopharma Holdings Earnings release: H2 2024

Mar 31, 2025, 9:00 AM EDT - 1 year ago

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Connect Biopharma Holdings Quarterly report: H1 2024

Sep 5, 2024, 4:00 PM EDT - 2 years ago

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Connect Biopharma Holdings Slides: Corporate Presentation

Aug 6, 2024, 2:00 AM EDT - 2 years ago

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Connect Biopharma Holdings Annual report: H2 2023

Apr 16, 2024, 4:00 PM EDT - 2 years ago

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Connect Biopharma Holdings Quarterly report: H2 2023

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Connect Biopharma Holdings Quarterly report: H2 2023


Teshuvahh
Teshuvahh Sep. 14 at 12:13 PM
$CNTB I find it mildly constructive if they release tomorrow and are confident enough to take results questions in realtime.
0 · Reply
Carnagex
Carnagex Sep. 14 at 12:03 PM
$CNTB agree.
1 · Reply
JohnFromLongRobust
JohnFromLongRobust Sep. 14 at 11:24 AM
$CNTB If they don’t release today or tomorrow i’ll be surprised
0 · Reply
raingang
raingang Sep. 14 at 6:22 AM
$CNTB must be released within few hours
0 · Reply
mulc
mulc Sep. 14 at 6:13 AM
$CNTB Must of this is inaccurate. 1. There is an actual 2024 exposure-response analysis saying rademikibart has an approximately 25-day half-life, used to support monthly dosing in atopic dermatitis. The peer-reviewed Phase 1 PK paper explicitly says rademikibart has nonlinear, target-mediated clearance, so its half-life is concentration-dependent; After a single 600-mg SC dose, rademikibart was detectable for a median of approximately 56 days in the Phase 1 study. 2: This mixes up three completely different quantities: dose administered ≠ drug amount remaining in body ≠ plasma concentration. And none of those is the same as steady state. 3: SC bioavailability - You cannot derive plasma concentration at Day 28 by simply dividing 600 mg in half. 4: The major asthma study wasn't a China trial. Most rademikibart FEV₁ improvement occurred during Week 1 and was sustained through Week 24. Also Seabreeze's primary endpoint is NOT FEV₁ at Day 28. Connect measures FEV₁ at Week 1.
3 · Reply
GoImugene
GoImugene Sep. 14 at 3:47 AM
$CNTB half life of Rademikibart is 25 days. So the blood level of the dosage of 600mg SubQ at the 28 day period should be close to a 300 mg steady state level. Initial improvements have been rapid for the treatment arm in the China trial, but the SOC arm tends to ketch up somewhat at 28 day mark making stat Sig very close to p<0.05. It will be close. The Iseparate IV push trial will be easier to predict the outcome, which I believe will be stat sig in the future.
1 · Reply
GoImugene
GoImugene Sep. 14 at 3:22 AM
$CNTB is the September readout for SubQ route? Yes. For 2 minute IV push? No
0 · Reply
Teshuvahh
Teshuvahh Sep. 13 at 8:44 PM
$CNTB been waiting for this moment for so long…
0 · Reply
Carnagex
Carnagex Sep. 13 at 2:24 PM
$CNTB when preparing for a major presentation at a conference it takes time to produce the slides and prepare for the presentation. I believe that scheduling the HC Wainwright fireside chat on September 3 was done from a position of knowledge of the data. The presentation at the conference was scheduled in advance, but not the fireside chat. That was announced on September 3. Major presentations take 2 to 3 weeks to put together and I believe it would be lethal to the company to schedule a major financial fireside chat, not knowing the data or having ugly data. To schedule that fireside chat without knowing your data would be a seriously unusual and reckless move by the CEO. I put heavy weight on the fact that they have some data from one of the two trials or both that is positive.
2 · Reply
DMaulST
DMaulST Sep. 12 at 5:46 PM
2 · Reply
Yourgflikesmycalloptions
Yourgflikesmycalloptions Sep. 12 at 1:27 AM
$CNTB Im not sure why when someone posts a ”bearish” opinion it automatically offends people. the ones that bicker or take offense over an opinion of a penny stock just shows you they dont realize that the market doesnt care about your emotions. no matter how much of a fanboy you might be or glaze a company the market doesnt care. my bearish opinion comes from lasts weeks violent price correction. MILLIONS in volume averaged the duration of the downfall. someone unloaded a shit ton of shares. right before…pay attention to this…MAKE OR BREAK DATA for the company. why would someone offload MILLIONS of shares prior to a ”home run” data read out? 98% of stocks are controlled by the 10% of the wealthiest people.…they always know before the rest of us.
4 · Reply
mulc
mulc Sep. 11 at 8:55 PM
$CNTB This was scheduled 4 months ago. I am not claiming they know the outcome yet. But seems to me that they are at least very confident about this trial. This was scheduled after April unblinded results. And this isn't some general biotech conference. The official speaker faculty includes people from AstraZeneca, Sanofi, Johnson & Johnson, Merck, respiratory specialists and other COPD-development companies. GLTA, hoping results come Monday pre-market.
0 · Reply
mulc
mulc Sep. 11 at 8:46 PM
$CNTB SO: Monday, September 14: The H.C. Wainwright 28th Annual Global Investment Conference: Sep: 14–16 Tuesday, September 15, 9:30 a.m. Boston time: Barry Quart speaks at the COPD Drug Development Summit in Boston. Tuesday, September 15, 11:30 a.m. ET: Connect Biopharma is also scheduled for its H.C. Wainwright fireside chat. Not the interesting part: What exactly is Barry speaking about? “Repositioning Rapid Acting IL-4Rα Biologics for Acute Exacerbations in Asthma & COPD: A Dual-Phase Approach to Rapid Lung Function Recovery & Inflammatory Control.” Barry will argue three things. * First, that rapidly acting IL-4Rα antibodies can potentially be used during an acute asthma or COPD exacerbation * he will discuss recovery of airway function within “minutes to hours,” leading to clinically meaningful FEV1 improvement. * “dual-phase” treatment concept: acute dose → rapid improvement in lung function → continued IL-4/IL-13 inflammatory suppression → sustained control after the exacerbation.
0 · Reply
stevie2times
stevie2times Sep. 11 at 8:25 PM
$CNTB Monday AM early 🔥
1 · Reply
mulc
mulc Sep. 11 at 7:39 PM
$CNTB Yes they changed wording in july or august. Regardless it would be strange not to publish results before the conference I think. So I am banking on monday.
3 · Reply
JohnFromLongRobust
JohnFromLongRobust Sep. 11 at 7:17 PM
$CNTB it says september 2026 not early september.
0 · Reply
FeliciaMath
FeliciaMath Sep. 11 at 6:48 PM
sold $CNTB at 1.98. lost $96/5%
0 · Reply
Asensus2023
Asensus2023 Sep. 11 at 6:20 PM
$CNTB close 2.10
0 · Reply
JohnFromLongRobust
JohnFromLongRobust Sep. 11 at 5:13 PM
$CNTB bought today. GLTAL.
0 · Reply
Yourgflikesmycalloptions
Yourgflikesmycalloptions Sep. 11 at 3:44 PM
$CNTB short interest has exploded in the past 2 weeks. pair that with the violent recent repricing from a high around $2.77, its clear money shifted from betting for to now against. im out. will start a short position going into the weekend. GLTA.
2 · Reply
silentziler
silentziler Sep. 11 at 2:17 PM
$CNTB Im not f**king leaving!!
0 · Reply
Acliammcr
Acliammcr Sep. 11 at 1:53 PM
Holding all $CNTB $SOAR $VMAR $GNS shares despite being up previously to now down slightly. Was losing money day trading so thought I’d try my luck swinging for catalyst etc … I don’t like it 😅😂😂😂 will hold for gold unless dd suggests otherwise but for now I’m bullish on these. $CNTB is defo a lotto play but certain aspects of my DD tell me to wait out the result. Good luck bulls
0 · Reply