Stoke Therapeutics Inc STOK

$24.17 -0.44 (-1.79%)

Valuation

Market cap
1,587,985,000
Revenue TTM
$184,420,000
Net income TTM
$-6,890,000
PE ratio
0.00
Forward PE
—
Profit margin
-3.74%
Debt to equity
0.00

Trading

Volume
880,100
Avg volume
886,682
Day's range
$23.64 – $24.61
Shares out
64,526,000
Stochastic %K
58%
Beta
1.26
Analysts
Strong Sell
Price target
$46.44

Price

Company profile

Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of au...

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Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy; and Zorevunersen (STK-001), an investigational new medicine for the treatment of Dravet syndrome is being evaluated in phase 3 clinical trials. The company also develops programs focused on various targets, including haploinsufficiency diseases of the central nervous system and eye. It has a license and collaboration with Biogen Inc. for the development and commercialization of zorevunersen medicine for the treatment of Dravet syndrome; and Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of genetic neurodevelopmental diseases. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Phone
781 430 8200
Website
https://www.stoketherapeutics.com
Address
45 Wiggins Avenue, Bedford, United States

Latest news

Stocktwits

JFais Oct 12, 12:19 PM
$STOK - to DD list, $1.4B EV with phase 3 Dravet readout Q3 2027 & initial phase 1 POC data for ADOA 1H 27. Like the TANGO platform tech readthrough to additional indications (moving into cardiac as well)
0 replies
TwongStocks Oct 5, 11:01 AM
$STOK Announces Completion of Successful Meeting with the FDA to Align on Planned U.S. NDA for Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome https://www.businesswire.com/news/home/20261005238322/en/Stoke-Therapeutics-Announces-Completion-of-Successful-Meeting-with-the-FDA-to-Align-on-Planned-U.S.-NDA-for-Zorevunersen-an-Investigational-Medicine-for-the-Treatment-of-Dravet-Syndrome Following the discussion with the FDA, Stoke now plans to use a multicomponent assessment of four prespecified Vineland-3 subdomains to evaluate changes in cognition and behavior in the Phase 3 EMPEROR study. Phase 3 readout anticipated in the third quarter of 2027 to complete the planned U.S. NDA submission in the second half of 2027
0 replies
Night_Owl_Biotech Sep 26, 1:43 AM
$STOK is off 26% over the last 4 weeks. As near as we can tell, the evidence suggests STOK's Zorevunersen is as likely to be approved for Dravet as any peer submission targeting any non-oncology disease/condition. The graph compares STOK analyst consensus revenue estimates v $IRON which, as we understand it, also anticipates approval in the near-term. More important, analysts project both to generate roughly the same revenues over the next 9 years. Analysts project STOK to outsell IRON by roughly 10% yet STOK now trades at a meaningfully lower valuation. Revenue multiples are provided. More than 10 analysts cover both & at least 6 for each provide projections through FY35. We're unaware of either's anticipated gross manufacturing margins. If anyone can provide any insight it would genuinely be appreciated. This is not investment advice. $XBI $IBB
1 replies
justiceforb_85 Sep 24, 1:56 AM
$STOK added. Selloff overdone. Zorevunersen likely to be the first disease-modifying drug in dravet syndrome.
2 replies
Quantumup Sep 10, 4:22 PM
Goldman Sachs reiterated $STOK Buy-$44 after hosting an investor meeting w, Stoke Therapeutics' mgmt (CEO, CPO & CCASP). $BIIB PRAX DRUG OVID HLUBF HLBBF IONS HRMY SUPN UCBJY JAZZ PYCFX ABEO SPHDF ABEO Here's what Goldman Sachs said in its note: https://x.com/Quantumup1/status/2098084604477391306?s=20
0 replies
LibertarianTreehugger Sep 4, 4:09 PM
Four-Year Data Offer New Hope for Children With Dravet Syndrome: https://jlsfund.substack.com/p/four-year-data-offer-new-hope-for $BIIB $STOK
0 replies
Merlintrader Sep 4, 11:22 AM
Biotech Radar — September 4, 2026: $IONS, $STOK, $CLYM & $APVO Lead an FDA, Dravet, IgAN and AML Tape https://www.merlintrader.com/biotech-radar-evaluating-ions-stok-clym-apvo/
0 replies
Valentino123 Aug 31, 8:26 PM
$STOK There’s no rush, but I like having it on my radar
0 replies