Market Cap 8.34M
Revenue (ttm) 2.00M
Net Income (ttm) -3.06M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -153.00%
Debt to Equity Ratio 0.00
Volume 59,000
Avg Vol 444,324
Day's Range N/A - N/A
Shares Out 3.34M
Stochastic %K 21%
Beta 1.32
Analysts Strong Buy
Price Target $4.00

Company Profile

Cyclerion Therapeutics, Inc., a biopharmaceutical company, develops treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. It is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator for the treatment of rare kidney disease. It has a license agreement with Akebi...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 327 8778
Address:
245 First Street, Riverview II, 18th Floor, Cambridge, United States
EZYME22
EZYME22 Oct. 5 at 2:52 AM
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StockTwitsGhost
StockTwitsGhost Oct. 5 at 1:58 AM
$CYCN Bullish
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StockTwitsGhost
StockTwitsGhost Oct. 5 at 1:58 AM
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herowins
herowins Oct. 4 at 4:16 PM
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 9:58 PM
$MNPR If MNPR csn do it, so can $CYCN 💪🏽
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EZYME22
EZYME22 Oct. 3 at 8:53 PM
1 · Reply
StockTwitsGhost
StockTwitsGhost Oct. 3 at 8:52 PM
$CYCN 🐂
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herowins
herowins Oct. 3 at 7:36 PM
$CYCN Fin.
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 6:46 PM
$CYCN It's a compelling thesis, but unfortunately, CYCN has consistently demonstrated that they’re better suited to flipping burgers than negotiating with big pharma. Nothing they’ve executed or signed to date falls outside the familiar orbit of Peter Hecht, Ironwood, or MIT. Every deal and partnership has been a close-hold arrangement with existing friends or past colleagues: the Graul hire came from Ironwood, the Tisento deal was through Hecht, the J. Wood private placement—again, Hecht. CVCO ties back to Ironwood and Hecht. Even their MIT involvement is via board overlap, and their Regis virtual office, patent, and trademark work? All routed through Hecht's network at Ironwood and Tisento. It’s almost absurd how incapable they seem of stepping outside their comfort zone. A friend of mine calls it institutional laziness—and honestly, it fits. The central sun of this bizarre CYCN universe and orbit is Peter Hecht.
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EZYME22
EZYME22 Oct. 3 at 5:43 PM
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Latest News on CYCN
Cyclerion Therapeutics, Inc. - Pre Recorded Special Call

Sep 24, 2025, 12:53 PM EDT - 10 days ago

Cyclerion Therapeutics, Inc. - Pre Recorded Special Call


Regina Graul, Ph.D., Promoted to Chief Executive Officer

Aug 7, 2024, 7:00 AM EDT - 1 year ago

Regina Graul, Ph.D., Promoted to Chief Executive Officer


Cyclerion Appoints Regina Graul, Ph.D., as President

Dec 4, 2023, 8:00 AM EST - 1 year ago

Cyclerion Appoints Regina Graul, Ph.D., as President


Cyclerion Announces Reverse Stock Split

May 15, 2023, 1:00 PM EDT - 2 years ago

Cyclerion Announces Reverse Stock Split


Cyclerion Therapeutics to Host Pipeline Update Webinar

Apr 20, 2021, 7:00 AM EDT - 4 years ago

Cyclerion Therapeutics to Host Pipeline Update Webinar


EZYME22
EZYME22 Oct. 5 at 2:52 AM
0 · Reply
StockTwitsGhost
StockTwitsGhost Oct. 5 at 1:58 AM
$CYCN Bullish
0 · Reply
StockTwitsGhost
StockTwitsGhost Oct. 5 at 1:58 AM
0 · Reply
herowins
herowins Oct. 4 at 4:16 PM
0 · Reply
StockTwitsGhost
StockTwitsGhost Oct. 3 at 9:58 PM
$MNPR If MNPR csn do it, so can $CYCN 💪🏽
0 · Reply
EZYME22
EZYME22 Oct. 3 at 8:53 PM
1 · Reply
StockTwitsGhost
StockTwitsGhost Oct. 3 at 8:52 PM
$CYCN 🐂
0 · Reply
herowins
herowins Oct. 3 at 7:36 PM
$CYCN Fin.
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 6:46 PM
$CYCN It's a compelling thesis, but unfortunately, CYCN has consistently demonstrated that they’re better suited to flipping burgers than negotiating with big pharma. Nothing they’ve executed or signed to date falls outside the familiar orbit of Peter Hecht, Ironwood, or MIT. Every deal and partnership has been a close-hold arrangement with existing friends or past colleagues: the Graul hire came from Ironwood, the Tisento deal was through Hecht, the J. Wood private placement—again, Hecht. CVCO ties back to Ironwood and Hecht. Even their MIT involvement is via board overlap, and their Regis virtual office, patent, and trademark work? All routed through Hecht's network at Ironwood and Tisento. It’s almost absurd how incapable they seem of stepping outside their comfort zone. A friend of mine calls it institutional laziness—and honestly, it fits. The central sun of this bizarre CYCN universe and orbit is Peter Hecht.
1 · Reply
EZYME22
EZYME22 Oct. 3 at 5:43 PM
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 5:26 PM
$CYCN And yet for some reason the CYCN braintrust thinks hiding this from stockholders gives them a competitive market advantage. What are the odds J.Wood was provided this information? Dr. Graul how has your strategy worked out so far? Turns out Stella and Dot jewelry reveal videos aren’t the same as reveals for publically traded biotech companies.
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 4:43 PM
$CYCN The Closed-Loop Anesthesia Delivery (CLAD) system corresponds closely to MIT Case #20652M and its patents (e.g., US 11,813,406; US 12,311,113), which describe software and control methods for real-time modulation of neural activity. Developed by Dr. Emery Brown’s team at MIT and MGH, the technology integrates local field potential (LFP) recordings and EEG monitoring with pharmacokinetic/pharmacodynamic (PK/PD) models of anesthetic agents like propofol. Using a linear quadratic integral (LQI) controller, the system dynamically adjusts anesthetic infusion every 20 seconds based on brain state measurements, normalizing power in the 20-30 Hz frequency band as the feedback variable. This closed-loop control was validated in long-duration experiments in nonhuman primates, demonstrating robust unconsciousness regulation. Cyclerion’s investor materials reference a “tech-driven system” for brain connectivity resynchronization, which aligns with this patented neural control technology.
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 4:24 PM
$CYCN Someone contact CYCN to provide comment and color regarding my below post of MIT Case #25342P and Case #20652M and patents US 11,813,406 and US 12,311,113. Dr. Graul is this OUR technology?
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 4:18 PM
$CYCN Cyclerion likely licensed both MIT Case #25342P and Case #20652M. Case #25342P covers novel combinations of anesthetic agents for treating treatment-resistant depression, aligning with Cyclerion’s lead program and clinical trial plans; however, no public patents are currently available for this case, suggesting pending or confidential status. Case #20652M involves software and methods for controlling neural responses in deep brain regions, supporting the device and algorithmic system Cyclerion describes. This case has publicly available patents, including US 11,813,406 and US 12,311,113, which cover neural modulation technologies. Together, these cases provide a comprehensive IP package combining anesthetic therapy (25342P) with neural modulation technology (20652M). This dual license underpins Cyclerion’s integrated neuropsychiatric treatment approach, combining drug regimens with neuromodulation devices as reflected in their investor materials. https://tlo.mit.edu/industry-entrepreneurs/available-technologies
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Mr_Pithy
Mr_Pithy Oct. 3 at 3:15 PM
$CYCN F*CKING TOTALLY
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EZYME22
EZYME22 Oct. 3 at 2:22 PM
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 1:47 PM
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herowins
herowins Oct. 3 at 8:36 AM
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 4:27 AM
$CYCN Why did the biotech company hire a bunch of Red Sox fans for clinical trials? Because they’re already used to watching something fail over and over, then still believing it’s going to work next year. 🙌 🥳
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StockTwitsGhost
StockTwitsGhost Oct. 3 at 3:26 AM
$CYCN Do you smell that? Smells like the sweet scent of Red Sox fans' tears...😊
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StockTwitsGhost
StockTwitsGhost Oct. 2 at 8:51 PM
$CYCN @AshleySchaeffer_BMW Give them ideas? They’re overflowing with brilliant ideas. Just look at this gem from the Cyclerion braintrust: "I propose we announce our major neuro/TRD pivot—the one investors have been waiting over a year for—via a pre-recorded YouTube video. Let’s allow public comments at first, then shut them off as soon as they get critical. We’ll make sure to avoid mentioning anything important, like financing, and instead fill the 17-minute video with vague, meaningless bio word soup. Once the stock drops 20% the minute the video ends, we’ll go completely silent—ignore calls, dodge emails, and vanish from sight. All in favor? Aye aye aye aye aye…”
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Mr_Pithy
Mr_Pithy Oct. 2 at 7:06 PM
$CYCN F*CK ALL OF YOU LOSER FLIPPERS, SHORTS, DAY TRADERS, BEARS, TROLLS, FAKE BULLS AND THE SHINING TWINS. MR. PITHY IS STILL LONG AND STRONG. YOU BETTER STEP IT UP REGINA.
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