Market Cap 4.81M
Revenue (ttm) 2.00M
Net Income (ttm) -3.06M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -153.00%
Debt to Equity Ratio 0.00
Volume 75,800
Avg Vol 861,398
Day's Range N/A - N/A
Shares Out 3.34M
Stochastic %K 14%
Beta 1.13
Analysts Strong Buy
Price Target $4.00

Company Profile

Cyclerion Therapeutics, Inc., a biopharmaceutical company, develops treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. It is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator for the treatment of rare kidney disease. It has a license agreement with Akebi...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 327 8778
Address:
245 First Street, Riverview II, 18th Floor, Cambridge, United States
EZYME22
EZYME22 Nov. 15 at 12:59 AM
$CYCN TO CYCLERION if listening. Some and potentially many of us retail investors genuinely believe in your mission. Treatment-Resistant Depression is an area that urgently needs innovation, and we want to stay supportive of the work you’re doing. However, the lack of basic transparency — not hype, just clear, consistent, and timely updates — makes it difficult to stay confidently invested. More direct interaction with investors, including live communication or accessible updates that clearly outline your plan and path forward, would go a long way in building trust. Please do better. It’s not just investors depending on your progress.
0 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 14 at 8:05 PM
$CYCN @skyrockets_Inc Larry🦜🤓 is back. 🧵 As disclosed in Cyclerion’s (CYCN) 10-Q filed November 12, 2025, the Option to License Agreement with CVCO for Olinciguat was terminated, and all rights to the molecule reverted fully to Cyclerion. Under the terms of a standard option agreement, CVCO held only the right to exercise a license but typically would not obtain rights to develop, commercialize, or move the molecule into clinical studies prior to exercising the option. While some option agreements may include limited interim development rights during the option period, any such rights would terminate upon termination of the option agreement unless explicitly preserved through survival provisions or a separate standalone agreement. Consequently, CVCO’s August 21, 2025 press release announcing progression of the molecule into a Phase 2 study with Karolinska Institute raises significant questions about the legal basis for that development activity,……
1 · Reply
rogueoctopus
rogueoctopus Nov. 14 at 5:46 PM
$CYCN 6+?
1 · Reply
Eliza1
Eliza1 Nov. 14 at 4:20 PM
$CYCN this should look like $CYPH
1 · Reply
skyrockets_Inc
skyrockets_Inc Nov. 14 at 4:02 PM
$CYCN I received an email back from CYCN , but it was from their lawyer. See image below. My original email to them is in the comment section below. It was too long to post here.
2 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 13 at 9:43 PM
$CYCN Random tbought. @skyrockets_Inc The Q3 10-Q lists 3,925,314 shares were outstanding. J. Wood Capital filed its Schedule 13G six months late on October 17, 2025, reporting 181,818 shares, about 5.4% which was prior to the dilution. After dilution their ownership fell to 4.66%. Does this suggest J Wood’s late filing may have been to avoid disclosing their ownership because they were aware that Cyclerion was going to tap the ATM because they knew Cyclerion wasn’t going to get a mixed shelf PIPE?
2 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 13 at 8:06 PM
$CYCN The CEO and company are remarkable. Today, shareholders sent emails, including to the CYCN board member and Tony Colasin. There’s a theory that the BOD, as busy professionals, aren’t fully aware of the day-to-day issues we raise with Regina. As a result, shareholders are forwarding prior communications to the board to ensure the board has proper visibility. Notably, as of 11 a.m. today, Cyclerion’s site still hadn’t been updated to remove CVCO. I contend leaving the CVCO information up on the Cyclerion website almost a full 24hrs after their 10-Q disclosed the deal was cancelled is/was materially mislesding.
3 · Reply
Eliza1
Eliza1 Nov. 13 at 7:22 PM
$CYCN $CYCU is going on A squeeze-it is time for $CYCN to do the same. Too bad the company didn't release a PR about their improved Balance sheet. Perhaps AH.
1 · Reply
skyrockets_Inc
skyrockets_Inc Nov. 13 at 6:56 PM
$CYCN Random volume uptick on Nov 15, 2024 followed by downward pressure for following 2 weeks to all time low. Fast forward to now . Random volume uptick Nov 10, 2025 (almost same exact volume as before) followed by now downward pressure to again all time lows. Will history repeat itself within the next 2 weeks with a MAJOR pop upward? If charts could speak.....
1 · Reply
Eliza1
Eliza1 Nov. 13 at 6:55 PM
$CYCN Just watch.
0 · Reply
Latest News on CYCN
Cyclerion Therapeutics, Inc. - Pre Recorded Special Call

Sep 24, 2025, 12:53 PM EDT - 7 weeks ago

Cyclerion Therapeutics, Inc. - Pre Recorded Special Call


Regina Graul, Ph.D., Promoted to Chief Executive Officer

Aug 7, 2024, 7:00 AM EDT - 1 year ago

Regina Graul, Ph.D., Promoted to Chief Executive Officer


Cyclerion Appoints Regina Graul, Ph.D., as President

Dec 4, 2023, 8:00 AM EST - 2 years ago

Cyclerion Appoints Regina Graul, Ph.D., as President


Cyclerion Announces Reverse Stock Split

May 15, 2023, 1:00 PM EDT - 2 years ago

Cyclerion Announces Reverse Stock Split


Cyclerion Therapeutics to Host Pipeline Update Webinar

Apr 20, 2021, 7:00 AM EDT - 4 years ago

Cyclerion Therapeutics to Host Pipeline Update Webinar


EZYME22
EZYME22 Nov. 15 at 12:59 AM
$CYCN TO CYCLERION if listening. Some and potentially many of us retail investors genuinely believe in your mission. Treatment-Resistant Depression is an area that urgently needs innovation, and we want to stay supportive of the work you’re doing. However, the lack of basic transparency — not hype, just clear, consistent, and timely updates — makes it difficult to stay confidently invested. More direct interaction with investors, including live communication or accessible updates that clearly outline your plan and path forward, would go a long way in building trust. Please do better. It’s not just investors depending on your progress.
0 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 14 at 8:05 PM
$CYCN @skyrockets_Inc Larry🦜🤓 is back. 🧵 As disclosed in Cyclerion’s (CYCN) 10-Q filed November 12, 2025, the Option to License Agreement with CVCO for Olinciguat was terminated, and all rights to the molecule reverted fully to Cyclerion. Under the terms of a standard option agreement, CVCO held only the right to exercise a license but typically would not obtain rights to develop, commercialize, or move the molecule into clinical studies prior to exercising the option. While some option agreements may include limited interim development rights during the option period, any such rights would terminate upon termination of the option agreement unless explicitly preserved through survival provisions or a separate standalone agreement. Consequently, CVCO’s August 21, 2025 press release announcing progression of the molecule into a Phase 2 study with Karolinska Institute raises significant questions about the legal basis for that development activity,……
1 · Reply
rogueoctopus
rogueoctopus Nov. 14 at 5:46 PM
$CYCN 6+?
1 · Reply
Eliza1
Eliza1 Nov. 14 at 4:20 PM
$CYCN this should look like $CYPH
1 · Reply
skyrockets_Inc
skyrockets_Inc Nov. 14 at 4:02 PM
$CYCN I received an email back from CYCN , but it was from their lawyer. See image below. My original email to them is in the comment section below. It was too long to post here.
2 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 13 at 9:43 PM
$CYCN Random tbought. @skyrockets_Inc The Q3 10-Q lists 3,925,314 shares were outstanding. J. Wood Capital filed its Schedule 13G six months late on October 17, 2025, reporting 181,818 shares, about 5.4% which was prior to the dilution. After dilution their ownership fell to 4.66%. Does this suggest J Wood’s late filing may have been to avoid disclosing their ownership because they were aware that Cyclerion was going to tap the ATM because they knew Cyclerion wasn’t going to get a mixed shelf PIPE?
2 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 13 at 8:06 PM
$CYCN The CEO and company are remarkable. Today, shareholders sent emails, including to the CYCN board member and Tony Colasin. There’s a theory that the BOD, as busy professionals, aren’t fully aware of the day-to-day issues we raise with Regina. As a result, shareholders are forwarding prior communications to the board to ensure the board has proper visibility. Notably, as of 11 a.m. today, Cyclerion’s site still hadn’t been updated to remove CVCO. I contend leaving the CVCO information up on the Cyclerion website almost a full 24hrs after their 10-Q disclosed the deal was cancelled is/was materially mislesding.
3 · Reply
Eliza1
Eliza1 Nov. 13 at 7:22 PM
$CYCN $CYCU is going on A squeeze-it is time for $CYCN to do the same. Too bad the company didn't release a PR about their improved Balance sheet. Perhaps AH.
1 · Reply
skyrockets_Inc
skyrockets_Inc Nov. 13 at 6:56 PM
$CYCN Random volume uptick on Nov 15, 2024 followed by downward pressure for following 2 weeks to all time low. Fast forward to now . Random volume uptick Nov 10, 2025 (almost same exact volume as before) followed by now downward pressure to again all time lows. Will history repeat itself within the next 2 weeks with a MAJOR pop upward? If charts could speak.....
1 · Reply
Eliza1
Eliza1 Nov. 13 at 6:55 PM
$CYCN Just watch.
0 · Reply
skyrockets_Inc
skyrockets_Inc Nov. 13 at 4:06 PM
$CYCN Well first thing is they failed on negotiations to outlicense their drug Olinciguat w/ CVCO on Oct 23, after an entire year of negotiation. But more importantly if you look at the stock price on Oct 23 it was ~2.10 and it dropped all the way down to ~1.45 before the 10q yesterday where they revealed this termination of the agreement. So someone on the inside was tipped off and started selling. This needs to be reported to the SEC tbh. That information should have been MATERIAL and released in an 8-k back in October.
2 · Reply
AshleySchaeffer_BMW
AshleySchaeffer_BMW Nov. 13 at 4:05 PM
$CYCN remember folks at least we're not in KRRO
0 · Reply
P_etheris
P_etheris Nov. 13 at 1:54 PM
$CYCN What in the actual F is happening here??? I am must be lacking data to understand this movements 🤣 I am smelling naked shorts from Group One and Geode…
1 · Reply
AshleySchaeffer_BMW
AshleySchaeffer_BMW Nov. 13 at 3:24 AM
$CYCN On September 3, 2025, the Company and Akebia entered into a Material Purchase Agreement (the “Purchase Agreement”) relating to the purchase of additional development materials (the "Additional Development Materials") by Akebia for Akebia's use pursuant to the Akebia License Agreement. Akebia paid $0.8 million to the Company for the purchase during the three and nine months ended September 30, 2025 and the Additional Development Materials were delivered to Akebia as of September 30, 2025.
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Eliza1
Eliza1 Nov. 13 at 1:34 AM
$ODP $CYCN the only other stock this entity has talked about $ODP and look at how wrong he was! He is hired to talk down $CYCN and he is not bullish and just paid to post by the short funds.
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StockTwitsGhost
StockTwitsGhost Nov. 13 at 12:54 AM
$CYCN 😆 Come on Regina get it together. https://x.com/GainOf1/status/1988762648557810025
1 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 12 at 11:54 PM
$CYCN @Mr_Pithy What are your thoughts on this from the 10-Q. I have not tracked Praliciguat development. Akebia Material Purchase Agreement (Sep 3, 2025) Purpose: Akebia purchased additional development materials for use under the license agreement. Payment: $0.8 million for materials delivered by September 30, 2025.
2 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 12 at 10:46 PM
$CYCN Well the good news is the 181,818 shares that J Wood Cap and Hecht purchased through the private placement for $499,999.50 on March 25 are now valued at approximately $223,000. I wonder if they shorted the stock? Not an accusation, just a question.
3 · Reply
Eliza1
Eliza1 Nov. 12 at 10:42 PM
$CYCN $CYPH initially went down after their report. That turned out to be a mistake.
0 · Reply
StockTwitsGhost
StockTwitsGhost Nov. 12 at 10:32 PM
$CYCN I wonder what authority CVCO had to release their PR on Aug 21 about the Phase 2 with Karolinska when clearly they had not secured the license for olinciguat. I wonder if this soured negotiations. Either way olinciguat is ours, CVCO payments is ours, and any collaborations with Karolinska is ours. There isn't much positive I have to say about the Cyclerion management, but this is a good move by the CYCN board of directors. There is much to this...Colasin's contact information is in the press release, @skyrockets_Inc you want to try and contact him for a comment on what happened. https://www.prnewswire.com/news-releases/cvco-therapeutics-and-karolinska-university-hospital-announce-collaboration-to-advance-understanding-of-microvascular-dysfunction-using-magnetic-resonance-perfusion-imaging-302535279.html
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Eliza1
Eliza1 Nov. 12 at 10:27 PM
$CYCN their revenue has tripled-their loss is much less than last year, this should be trading at $10 right now-there has been no major dilution at all and any licensing agreement that didn't work out is not a huge deal at the moment. They will get it with someone else.
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skyrockets_Inc
skyrockets_Inc Nov. 12 at 10:22 PM
$CYCN Pros: -Book value is essentially the same. Even with the added shares from the ATM. Stockholder equity is more this quarter due to 800k revenue from AKBA agreement and ATM sale. 9.5m stockholder equity w/ 3.8 shares outstanding still leaves this at book value of around 2.50/share. -Still have 10% ownership stake in Tisento Cons: -They continue to tap into the ATM even at low prices to raise funds when needed. Will need real investment from large funds down to the line to complete their plan in TRD. -They did not finalize the CVCO/Olinciguat agreement. Which I find very wild and strange as well. Looking forward to seeing what they have to say about that.
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