Market Cap 5.23B
Revenue (ttm) 1.00B
Net Income (ttm) 22.39M
EPS (ttm) N/A
PE Ratio 314.54
Forward PE N/A
Profit Margin 2.23%
Debt to Equity Ratio 1.23
Volume 2,079,600
Avg Vol 5,410,860
Day's Range N/A - N/A
Shares Out 127.83M
Stochastic %K 94%
Beta -0.19
Analysts Sell
Price Target $40.12

Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproli...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 977 5700
Website: apellis.com
Address:
100 Fifth Avenue, Waltham, United States
JFais
JFais Apr. 24 at 12:17 PM
Reminder some DCA purchases work out well, others not so much $APLS $BHVN $DERM
1 · Reply
JFais
JFais Apr. 23 at 12:37 PM
Eventful Week: -Redeployed rest of $APLS buyout proceeds -Shared DD on a new commercial setup -Published April Playbook this morning (potential names on radar for future purchase, I continually prioritize these based on actionability & which has most favorable r/r) -Coffee at the Close call Friday $XBI
0 · Reply
JFais
JFais Apr. 22 at 7:32 PM
$APLS- all out, may the boring base hits (& occasional homerun) continue
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 19 at 4:53 PM
$TARS valuation, analyst consensus & related revenue multiples versus actual M&A revenue multiples paid to acquire $FOLD & $APLS Analysts project TARS to generate more revenues over the next 5 & 9 years than FOLD. FOLD was acquired for an enterprise value of $4.8B. Analysts project TARS to generate slightly lower revenues over the next 5 & 9 years than APLS. APLS was acquired for an enterprise value of $5.6B. If analysts project TARS revenues to be in between FOLD & APLS, does that suggest TARS' hypothetical M&A enterprise value would be somewhere in between the 2. TARS revenues generate higher gross margins than both FOLD & APLS. Does this suggest TARS would (again hypothetically) command a higher M&A exit multiple? We're curious what genuine TARS investors believe. $XBI $IBB
1 · Reply
anachartanalyst
anachartanalyst Apr. 17 at 3:02 PM
$APLS https://anachart.com/wp-content/uploads/ana_temp/1776438120_soc-img.jpg
0 · Reply
erevnon
erevnon Apr. 17 at 2:17 PM
Wells Fargo downgrades Apellis Pharmaceuticals $APLS from Overweight to Equal-Weight and raises the price target from $26 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
JFais
JFais Apr. 16 at 1:21 PM
$TVTX- had to rain on the parade didn't you @adamfeuerstein 😉 Good news $TVTX will build out the FSGS market and better treatments will follow (CCR2 blocker DMX-200 & complement inhibitors like $APLS $BIIB Empaveli in P3, BAFF APRIL a la atacicept & $VRTX poveticacicept, etc)
0 · Reply
Pharmer23
Pharmer23 Apr. 10 at 1:08 PM
$SRPT I was in $APLS FOR AGES . Vasculitis scare and stock tanked from almost 90 and stayed shit for years . Out of no where but out with 140 percent premium . Don’t be an idiot thinking this will be 20 bucks forever . Too much going on , especially now these arrowhead assets showed some serious potential . BP will want to get this cheap . PMOS are not going anywhere btw . Exondys reslly has no risk near term . The other two still won’t get pulled . They’re still being prescribed at over 90 % retention . Why would prescribers give something to these poor kids for 10 years if it was shit an didn’t work ? Elevidys data shows slowing of disease a suspect will only get better at year 4.5,6 etc . There’s too much going do this to stay here in the 20s
3 · Reply
JFais
JFais Apr. 9 at 11:31 PM
Put 14%pw of $APLS profits to work (sooner than I'd planned) - working on the remaining 6%pw (no rush, would prefer a pullback but again each day's a blank slate to look at current r/r)
0 · Reply
RunnerSignals
RunnerSignals Apr. 7 at 3:26 PM
$CAR $SSL $APLS $AA $ELVN highs are printing but volume not confirming across the board
0 · Reply
Latest News on APLS
Why This Pharma Stock More Than Doubled Today

Mar 31, 2026, 9:41 AM EDT - 24 days ago

Why This Pharma Stock More Than Doubled Today

BIIB


Biogen to Acquire Apellis Pharmaceuticals for $5.6 Billion

Mar 31, 2026, 7:44 AM EDT - 24 days ago

Biogen to Acquire Apellis Pharmaceuticals for $5.6 Billion

BIIB


Biogen to buy Apellis Pharmaceuticals for $5.6 billion

Mar 31, 2026, 7:05 AM EDT - 24 days ago

Biogen to buy Apellis Pharmaceuticals for $5.6 billion

BIIB


Apellis Valuation Ignores Empaveli Potential, Says Analyst

Jan 21, 2026, 1:14 PM EST - 3 months ago

Apellis Valuation Ignores Empaveli Potential, Says Analyst


FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals

Apr 1, 2025, 2:11 PM EDT - 1 year ago

FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals


JFais
JFais Apr. 24 at 12:17 PM
Reminder some DCA purchases work out well, others not so much $APLS $BHVN $DERM
1 · Reply
JFais
JFais Apr. 23 at 12:37 PM
Eventful Week: -Redeployed rest of $APLS buyout proceeds -Shared DD on a new commercial setup -Published April Playbook this morning (potential names on radar for future purchase, I continually prioritize these based on actionability & which has most favorable r/r) -Coffee at the Close call Friday $XBI
0 · Reply
JFais
JFais Apr. 22 at 7:32 PM
$APLS- all out, may the boring base hits (& occasional homerun) continue
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 19 at 4:53 PM
$TARS valuation, analyst consensus & related revenue multiples versus actual M&A revenue multiples paid to acquire $FOLD & $APLS Analysts project TARS to generate more revenues over the next 5 & 9 years than FOLD. FOLD was acquired for an enterprise value of $4.8B. Analysts project TARS to generate slightly lower revenues over the next 5 & 9 years than APLS. APLS was acquired for an enterprise value of $5.6B. If analysts project TARS revenues to be in between FOLD & APLS, does that suggest TARS' hypothetical M&A enterprise value would be somewhere in between the 2. TARS revenues generate higher gross margins than both FOLD & APLS. Does this suggest TARS would (again hypothetically) command a higher M&A exit multiple? We're curious what genuine TARS investors believe. $XBI $IBB
1 · Reply
anachartanalyst
anachartanalyst Apr. 17 at 3:02 PM
$APLS https://anachart.com/wp-content/uploads/ana_temp/1776438120_soc-img.jpg
0 · Reply
erevnon
erevnon Apr. 17 at 2:17 PM
Wells Fargo downgrades Apellis Pharmaceuticals $APLS from Overweight to Equal-Weight and raises the price target from $26 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
JFais
JFais Apr. 16 at 1:21 PM
$TVTX- had to rain on the parade didn't you @adamfeuerstein 😉 Good news $TVTX will build out the FSGS market and better treatments will follow (CCR2 blocker DMX-200 & complement inhibitors like $APLS $BIIB Empaveli in P3, BAFF APRIL a la atacicept & $VRTX poveticacicept, etc)
0 · Reply
Pharmer23
Pharmer23 Apr. 10 at 1:08 PM
$SRPT I was in $APLS FOR AGES . Vasculitis scare and stock tanked from almost 90 and stayed shit for years . Out of no where but out with 140 percent premium . Don’t be an idiot thinking this will be 20 bucks forever . Too much going on , especially now these arrowhead assets showed some serious potential . BP will want to get this cheap . PMOS are not going anywhere btw . Exondys reslly has no risk near term . The other two still won’t get pulled . They’re still being prescribed at over 90 % retention . Why would prescribers give something to these poor kids for 10 years if it was shit an didn’t work ? Elevidys data shows slowing of disease a suspect will only get better at year 4.5,6 etc . There’s too much going do this to stay here in the 20s
3 · Reply
JFais
JFais Apr. 9 at 11:31 PM
Put 14%pw of $APLS profits to work (sooner than I'd planned) - working on the remaining 6%pw (no rush, would prefer a pullback but again each day's a blank slate to look at current r/r)
0 · Reply
RunnerSignals
RunnerSignals Apr. 7 at 3:26 PM
$CAR $SSL $APLS $AA $ELVN highs are printing but volume not confirming across the board
0 · Reply
JFais
JFais Apr. 7 at 1:33 PM
$TLX has risen to my #2 position after $APLS (still redeploying buyout proceeds) Encouraging Q1 report today (gaining share in PSMA diagnostic market + growing uptake for Gozellix) Follow it up with Pixclara & Zircaix approvals later this year (or 1H 27) => improving sentiment
0 · Reply
monoksop
monoksop Apr. 6 at 2:05 PM
$APLS I have a feeling this will hit $41 in the next couple of months.
0 · Reply
CapitalMonk
CapitalMonk Apr. 6 at 11:21 AM
$APLS Price: $40.41 (+0.05%) Trend: Bearish Market Bias (7D): Bearish Bias 📉 Expected Range: ±9.43% RSI: 89.4 | Momentum: Strong Momentum Volume: +20.9% vs avg Volatility: 30.55% Support: $16.83 | Resistance: $40.48 Tools used: https://www.trade-ideas.com Code: INTERSTOCK25
1 · Reply
Grimy4828
Grimy4828 Apr. 6 at 8:57 AM
$APLS 😂
0 · Reply
PaulLaurent
PaulLaurent Apr. 4 at 6:20 PM
🚀📈 Top Gainers 📈🚀 Last Week $GVH $SST $SKYQ $APLS $BFRG
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 4 at 5:16 PM
88% of comm'l-stage non-oncology focused bios that sell within 33 months of FDA approval are sold at meaningful gains for shareholders (versus their closing share price 2 days post approval). Only 11% of bios in this peer group sold 33 months post approval are sold at gains. The $APLS exit is consistent with this phenomenon. Empaveli was first approved on Friday 5/14/21. Had you acquired APLS shares 2 full trading days later (once settled), you would have paid $51.31 per share. $BIIB is buying APLS for $41.00 per share (plus a $2.00 CVR). Hence investors who acquired & held APLS over this period are down roughly 23% over the last 59 months. The phenomenon is the same in oncology except the window is 24 months (exactly 2 years). $IOVA just eclipsed 2 years. The evidence is overwhelming shareholder value is maximized via M&A exit within 2-3 years post approval $TARS is nearing 33 months (but will likely be an exception). It closed at $19.87 at approval +2 $CRMD ? This is not investment advice
3 · Reply
CamdenSignals
CamdenSignals Apr. 3 at 7:22 PM
$ETON — broke out of a 4 month consolidation. Relative strength vs SPY is strong. Watching $25.99 for continuation. $GSAT — holding up way better than the broader market. Want to see if it can clear $78. $INTC — above the 21 EMA with a golden cross still intact. $50.49 is the level. $ORKA — quietly holding gains while everything else sells off. $APLS — structure tightening. Could go either way but the compression is worth watching. Market is still in rough shape so I’m not chasing anything. Just mapping levels for when conditions improve. What’s everyone else watching?
0 · Reply
JFais
JFais Apr. 2 at 6:35 PM
1 · Reply
JFais
JFais Apr. 2 at 6:35 PM
0 · Reply
Fivish
Fivish Apr. 2 at 5:33 PM
$APLS what do yall think this will look like over the next few weeks?
0 · Reply
Stockman824
Stockman824 Apr. 2 at 2:52 PM
$APLS $LITE $NVDA $USO $VKTX Now that we are clearly on CNBC radar, we are BIC potential WL multiple drugs. IMO we continue to go up on this very significant mention and eventually get BO for over 200
0 · Reply
TrustButVerifi
TrustButVerifi Apr. 2 at 2:43 PM
$VKTX $34 going to----------------------- $234 ! Don't Miss!!! 24 Million Short Shares have No idea what is about to hit them1 $APLS $LITE $NVDA $USO
0 · Reply