Market Cap 2.82B
Revenue (ttm) 781.37M
Net Income (ttm) -197.88M
EPS (ttm) N/A
PE Ratio 73.55
Forward PE N/A
Profit Margin -25.32%
Debt to Equity Ratio 1.13
Volume 1,506,500
Avg Vol 2,871,268
Day's Range N/A - N/A
Shares Out 126.53M
Stochastic %K 41%
Beta 0.26
Analysts Strong Sell
Price Target $33.95

Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproli...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 977 5700
Website: apellis.com
Address:
100 Fifth Avenue, Waltham, United States
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 23 at 12:14 PM
$APLS RSI: 47.54, MACD: -0.2083 Vol: 0.57, MA20: 22.50, MA50: 23.44 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
UgoGreg
UgoGreg Feb. 21 at 5:18 PM
$APLS https://youtu.be/ygBN8MilTyc
0 · Reply
NicoleBerry928
NicoleBerry928 Feb. 21 at 8:00 AM
$APLS Apellis Pharmaceuticals develops complement inhibitor therapies. Commercial execution drives valuation. Pipeline expansion supports growth optionality.
1 · Reply
philosophernutz
philosophernutz Feb. 19 at 5:22 AM
$APLS The Year is 2037 and APLS is about to perform a miracle. No, they didn't discover the cure for Cancer. They will give guidance for the first time ever on an earnings call.
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 18 at 6:15 PM
$APLS Current Stock Price: $22.26 Contracts to trade: $22.0 APLS Feb 20 2026 Call Entry: $0.20 Exit: $0.26 ROI: 31% Hold ~29 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
philosophernutz
philosophernutz Feb. 18 at 5:49 PM
$APLS Even after Apls was added to the S&P 1000 index and 18 million shares were purchased by the big guns (black rock, vanguard) the price didn't move. 😭
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 16 at 7:42 PM
$APLS one new BIG buyer: Norges Bank
0 · Reply
ThatsNoMoon
ThatsNoMoon Feb. 14 at 8:10 PM
$APLS The opportunity cost is real…
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 13 at 6:39 PM
1 · Reply
philosophernutz
philosophernutz Feb. 10 at 7:19 PM
$APLS All I ask is for ANY type of guidance....ANY https://finance.yahoo.com/news/apellis-pharmaceuticals-host-conference-call-120000851.html
1 · Reply
Latest News on APLS
Apellis Valuation Ignores Empaveli Potential, Says Analyst

Jan 21, 2026, 1:14 PM EST - 4 weeks ago

Apellis Valuation Ignores Empaveli Potential, Says Analyst


Apellis Pharmaceuticals: The Picture Becomes Clearer

Aug 1, 2025, 2:29 PM EDT - 7 months ago

Apellis Pharmaceuticals: The Picture Becomes Clearer


Apellis Pharmaceuticals: Have Some Patience

May 20, 2025, 9:28 AM EDT - 9 months ago

Apellis Pharmaceuticals: Have Some Patience


Apellis Announces Craig Wheeler to Join the Board of Directors

Apr 21, 2025, 7:00 AM EDT - 11 months ago

Apellis Announces Craig Wheeler to Join the Board of Directors


FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals

Apr 1, 2025, 2:11 PM EDT - 11 months ago

FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals


Apellis Pharmaceuticals: A Mixed Bag

Mar 5, 2025, 2:06 PM EST - 1 year ago

Apellis Pharmaceuticals: A Mixed Bag


OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 23 at 12:14 PM
$APLS RSI: 47.54, MACD: -0.2083 Vol: 0.57, MA20: 22.50, MA50: 23.44 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
UgoGreg
UgoGreg Feb. 21 at 5:18 PM
$APLS https://youtu.be/ygBN8MilTyc
0 · Reply
NicoleBerry928
NicoleBerry928 Feb. 21 at 8:00 AM
$APLS Apellis Pharmaceuticals develops complement inhibitor therapies. Commercial execution drives valuation. Pipeline expansion supports growth optionality.
1 · Reply
philosophernutz
philosophernutz Feb. 19 at 5:22 AM
$APLS The Year is 2037 and APLS is about to perform a miracle. No, they didn't discover the cure for Cancer. They will give guidance for the first time ever on an earnings call.
1 · Reply
BillionerOfKing
BillionerOfKing Feb. 18 at 6:15 PM
$APLS Current Stock Price: $22.26 Contracts to trade: $22.0 APLS Feb 20 2026 Call Entry: $0.20 Exit: $0.26 ROI: 31% Hold ~29 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
0 · Reply
philosophernutz
philosophernutz Feb. 18 at 5:49 PM
$APLS Even after Apls was added to the S&P 1000 index and 18 million shares were purchased by the big guns (black rock, vanguard) the price didn't move. 😭
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 16 at 7:42 PM
$APLS one new BIG buyer: Norges Bank
0 · Reply
ThatsNoMoon
ThatsNoMoon Feb. 14 at 8:10 PM
$APLS The opportunity cost is real…
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Feb. 13 at 6:39 PM
1 · Reply
philosophernutz
philosophernutz Feb. 10 at 7:19 PM
$APLS All I ask is for ANY type of guidance....ANY https://finance.yahoo.com/news/apellis-pharmaceuticals-host-conference-call-120000851.html
1 · Reply
UgoGreg
UgoGreg Feb. 8 at 2:51 PM
$APLS https://youtu.be/b4CDDEB3OQo
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Feb. 7 at 2:01 AM
Valuation, analyst revenue estimates, FY25 YTD gross margin & related revenue multiples of all commercial-stage non-oncology focused bios with FDA approvals between 1/1/2021 & 12/31/2023. $ARDX $BCRX trade at the lowest multiples while their products generate the highest gross margins. BCRX's multiples do not consider its debt. $TARS $APLS & now $TVTX trade at the second lowest multiples. TVTX gross margins are almost 100%. TARS is competitive at 93%. Year 4/FY2029 multiples are provided because investment bankers often cite peer Year 4 M&A revenue multiples in their fair value opinions included in 14D9 filings. These tables are useful if you believe new drugs are worth some multiple and/or NPV of anticipated revenues & gross margin. M&A exits by far are most likely to maximize revenues for shareholders. This is not investment advice.
1 · Reply
Jockne40
Jockne40 Feb. 5 at 6:24 PM
$APLS someone steadily accumulating APlS, either buyout or hedge fund that will surprise with stake and demand selling it
3 · Reply
WidowWicks
WidowWicks Feb. 4 at 9:33 AM
$APLS biotech, geographic atrophy treatment
0 · Reply
APman
APman Feb. 3 at 5:52 PM
$APLS One solitary green in my watchlist
0 · Reply
BioRich
BioRich Feb. 3 at 4:59 PM
$APLS Was looking to streamline my portfolio and free up cash to buy more $GUTS, but this post by Zacks immediately changed my mind. Thanks Zacks! Follow/Subscribe for more suggestions and perspective. Would love to hear yours too. That's how we find these gems and learn. Let's make some (more) money. Cheers!
1 · Reply
ZacksResearch
ZacksResearch Feb. 3 at 2:03 PM
Q4 earnings season — these 5 drug & biotech names could surprise to the upside $ZTS, $PCRX, $APLS, $ACAD, and $DNLI are highlighted as poised to beat on fourth-quarter 2025 earnings, setting up a potential outperformance theme investors should have on their radar. See which drug & biotech stocks could deliver earnings upside 👉 https://www.zacks.com/stock/news/2827958/5-drugbiotech-stocks-likely-to-outperform-q4-earnings-estimates?cid=sm-stocktwits-2-2827958-teaser-31624&ADID=SYND_STOCKTWITS_TWEET_2_2827958_TEASER_31624
0 · Reply
Georgeson
Georgeson Feb. 2 at 7:30 PM
$APLS Maybe apls will do something similar to reverse CHMP's initial rejection: https://www.biospace.com/press-releases/press-release-sanofis-rezurock-recommended-for-eu-approval-by-the-chmp-to-treat-chronic-graft-vs-host-disease
2 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Jan. 31 at 5:17 PM
Change in share price YTD for all comm'l-stage non-oncology focused bios with market caps of $1 to $5.5B. $OCUL is the worst performer YTD. It appears a rumored Sanofi acq north of the $16/share offered last September fizzled out. Recall Sanofi announced it was buying DVAX last December. Only 10 of 171 new comm'l-stage non-oncology focused bios went to to create meaningful gains for S/Hs by staying independent (0 of 61 in oncology). M&A exits are, overwhelmingly, best for S/Hs historically $TARS If anyone can explain what's happened here it would be appreciated. Was it the JPM exclusion? The insider sales? The last TARS press release is dated 11/24/25 (2 months ago). We bought TARS last summer for $40 ish then sold in the high $50 s only to see TARS run to $80 $TVTX appears to trade @ reasonable multiples after the FDA extended the FSGS PDUFA back 3 months. $LGND investors often cite TVTX's royalties due. There's uncertainty but... Again, $APLS ? This is not investment advice. Just sharing
1 · Reply
RunnerSignals
RunnerSignals Jan. 29 at 10:07 PM
Is your portfolio ready for 94% upside? $CRCL $APLS $AMPX $INSM $GRAB are flashing huge buy signals https://stocksrunner.com/news/2026-01-29-today-stock-upgrade-analysis
1 · Reply
ronaldo7
ronaldo7 Jan. 29 at 2:46 PM
$APLS Sold yesterday and made over $15K in 16 days, thank you APLs
0 · Reply
sepsis74
sepsis74 Jan. 29 at 2:24 PM
$APLS S&P SmallCap 600 constituent Advanced Energy Industries Inc. (NASD: AEIS) will replace Comerica Inc. (NYSE: CMA) in the S&P MidCap 400, and Apellis Pharmaceuticals Inc. (NASD: APLS) will replace Advanced Energy Industries in the S&P SmallCap 600 effective prior to the opening of trading on Monday, February 2. S&P 500 constituent Fifth Third Bancorp (NASD: FITB) is acquiring Comerica in a deal expected to be completed soon, pending final closing conditions.
0 · Reply