Market Cap 3.01B
Revenue (ttm) 781.37M
Net Income (ttm) -197.88M
EPS (ttm) N/A
PE Ratio 76.23
Forward PE 98.05
Profit Margin -25.32%
Debt to Equity Ratio 1.13
Volume 1,839,900
Avg Vol 2,704,632
Day's Range N/A - N/A
Shares Out 126.53M
Stochastic %K 83%
Beta 0.37
Analysts Sell
Price Target $35.39

Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproli...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 977 5700
Website: apellis.com
Address:
100 Fifth Avenue, Waltham, United States
dogDazeSummer
dogDazeSummer Dec. 9 at 6:58 PM
$IFRX New on X & bluesky reminder Inflarx isn’t a “me too” biotech - it’s cutting edge / small molecule oral & brand new technology. https://www.mdpi.com/1422-0067/26/23/11693 Courtesy: x giger1964 “With drug candidates targeting pathway-specific initiation (anti-C1s, anti-MASP2), amplification (FD and FB inh) and effector ft (C5aR1 inh) in late-stage devpt, we finally enter a new era in complement-modulating therapies" “..some inflammation-related tumors, sustained and excessively high levels of C5a can lead to fatigue or exhaustion of immune cells, reducing their ability to kill tumor cells. In cases where tumor cells are able to secrete C5a, it can upregulate the expression of chemokine MCP-1, and promote the metastasis of colon cancer cells to the liver through inflammatory infiltration mediated by MCP-1. In a mouse model of colon cancer liver metastasis, the expression level of C5a is also significantly increased.” $BIIB $AMGN $APLS all there - but Inflarx only pure play.
0 · Reply
The_Fudge_ster
The_Fudge_ster Dec. 8 at 1:10 PM
$APLS we've tended to move in line with the other ophtho biotechs in the short term, so the tailwinds in wAMD space might carry things here a little too. I need to trim some shares on next spike. Just tired of waiting for Cedric to turn a profit here.
1 · Reply
The_Trading_Mechanic
The_Trading_Mechanic Dec. 7 at 11:36 PM
Healing Momentum Apellis Pharmaceuticals is currently testing the bottom of a key weekly gap near the $20 level, an area that has historically acted as a strong support zone. A confirmed breakout above the $29 level would signal renewed bullish momentum and open the path toward the $35.25 resistance, which aligns with prior supply and structural resistance. APLS looks primed for a bounce as selling pressure fades and momentum indicators begin to shift upward. With a clearly defined stop-loss at $18.50, this setup offers a strong risk-to-reward profile, giving traders controlled downside and meaningful upside potential. Fundamentally, positive sentiment continues around Apellis’ commercial rollout of Syfovre and its expanding pipeline in complement inhibition—adding further tailwind to the technical setup.
0 · Reply
4Reel
4Reel Dec. 5 at 9:04 PM
$APLS a good day, but someone went heavy on the 23 dollar puts the last hour for 12/19 so that was a lot of the pressure down. 1800 of the 2600 options today were 23 dollar puts 12/19 📝 i see u
0 · Reply
buylowandwait
buylowandwait Dec. 5 at 7:20 PM
$APLS The valuation is cheap, granted that the management team are scientists without business acumenship. But I believe that C3G/IC-MPGN is greatly under-appreciated ! GA expansion into other territory is under-appreciated ! Pipeline is also under-appreciated ! When tide turns, it runs like Tsunami, I hope :-)
1 · Reply
topstockalerts
topstockalerts Dec. 5 at 5:11 PM
$APLS not a bad place for a swing idea 💡
0 · Reply
ronaldo7
ronaldo7 Dec. 5 at 4:55 PM
$APLS Finally I am green…Should I sell or wait?
2 · Reply
JFais
JFais Dec. 5 at 4:31 PM
0 · Reply
Spanner1968
Spanner1968 Dec. 5 at 4:29 PM
$APLS pop..... did I miss something!
1 · Reply
JFais
JFais Dec. 5 at 4:26 PM
$APLS- Cool anecdote (physician FOMO) & differentiation emerging in PNH as well (safety edge)
1 · Reply
Latest News on APLS
Apellis Pharmaceuticals: The Picture Becomes Clearer

Aug 1, 2025, 2:29 PM EDT - 4 months ago

Apellis Pharmaceuticals: The Picture Becomes Clearer


Apellis Pharmaceuticals: Have Some Patience

May 20, 2025, 9:28 AM EDT - 7 months ago

Apellis Pharmaceuticals: Have Some Patience


Why Apellis Pharmaceuticals Wilted on Wednesday

May 7, 2025, 6:09 PM EDT - 7 months ago

Why Apellis Pharmaceuticals Wilted on Wednesday


Apellis Announces Craig Wheeler to Join the Board of Directors

Apr 21, 2025, 7:00 AM EDT - 8 months ago

Apellis Announces Craig Wheeler to Join the Board of Directors


FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals

Apr 1, 2025, 2:11 PM EDT - 9 months ago

FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals


Apellis Pharmaceuticals: A Mixed Bag

Mar 5, 2025, 2:06 PM EST - 9 months ago

Apellis Pharmaceuticals: A Mixed Bag


dogDazeSummer
dogDazeSummer Dec. 9 at 6:58 PM
$IFRX New on X & bluesky reminder Inflarx isn’t a “me too” biotech - it’s cutting edge / small molecule oral & brand new technology. https://www.mdpi.com/1422-0067/26/23/11693 Courtesy: x giger1964 “With drug candidates targeting pathway-specific initiation (anti-C1s, anti-MASP2), amplification (FD and FB inh) and effector ft (C5aR1 inh) in late-stage devpt, we finally enter a new era in complement-modulating therapies" “..some inflammation-related tumors, sustained and excessively high levels of C5a can lead to fatigue or exhaustion of immune cells, reducing their ability to kill tumor cells. In cases where tumor cells are able to secrete C5a, it can upregulate the expression of chemokine MCP-1, and promote the metastasis of colon cancer cells to the liver through inflammatory infiltration mediated by MCP-1. In a mouse model of colon cancer liver metastasis, the expression level of C5a is also significantly increased.” $BIIB $AMGN $APLS all there - but Inflarx only pure play.
0 · Reply
The_Fudge_ster
The_Fudge_ster Dec. 8 at 1:10 PM
$APLS we've tended to move in line with the other ophtho biotechs in the short term, so the tailwinds in wAMD space might carry things here a little too. I need to trim some shares on next spike. Just tired of waiting for Cedric to turn a profit here.
1 · Reply
The_Trading_Mechanic
The_Trading_Mechanic Dec. 7 at 11:36 PM
Healing Momentum Apellis Pharmaceuticals is currently testing the bottom of a key weekly gap near the $20 level, an area that has historically acted as a strong support zone. A confirmed breakout above the $29 level would signal renewed bullish momentum and open the path toward the $35.25 resistance, which aligns with prior supply and structural resistance. APLS looks primed for a bounce as selling pressure fades and momentum indicators begin to shift upward. With a clearly defined stop-loss at $18.50, this setup offers a strong risk-to-reward profile, giving traders controlled downside and meaningful upside potential. Fundamentally, positive sentiment continues around Apellis’ commercial rollout of Syfovre and its expanding pipeline in complement inhibition—adding further tailwind to the technical setup.
0 · Reply
4Reel
4Reel Dec. 5 at 9:04 PM
$APLS a good day, but someone went heavy on the 23 dollar puts the last hour for 12/19 so that was a lot of the pressure down. 1800 of the 2600 options today were 23 dollar puts 12/19 📝 i see u
0 · Reply
buylowandwait
buylowandwait Dec. 5 at 7:20 PM
$APLS The valuation is cheap, granted that the management team are scientists without business acumenship. But I believe that C3G/IC-MPGN is greatly under-appreciated ! GA expansion into other territory is under-appreciated ! Pipeline is also under-appreciated ! When tide turns, it runs like Tsunami, I hope :-)
1 · Reply
topstockalerts
topstockalerts Dec. 5 at 5:11 PM
$APLS not a bad place for a swing idea 💡
0 · Reply
ronaldo7
ronaldo7 Dec. 5 at 4:55 PM
$APLS Finally I am green…Should I sell or wait?
2 · Reply
JFais
JFais Dec. 5 at 4:31 PM
0 · Reply
Spanner1968
Spanner1968 Dec. 5 at 4:29 PM
$APLS pop..... did I miss something!
1 · Reply
JFais
JFais Dec. 5 at 4:26 PM
$APLS- Cool anecdote (physician FOMO) & differentiation emerging in PNH as well (safety edge)
1 · Reply
JFais
JFais Dec. 5 at 4:24 PM
$APLS (L) Another core holding running up (since Nov entry in high teens)
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Dec. 5 at 4:22 PM
$APLS jeepers-keep going...
0 · Reply
scott52
scott52 Dec. 5 at 3:48 PM
$APLS Fly you woman-faced winged donkey with peacock feathers sprouting out your ass, FLY! LoL.
0 · Reply
Pharmer23
Pharmer23 Dec. 5 at 3:17 PM
$APLS what the hell is happening .
0 · Reply
The_Fudge_ster
The_Fudge_ster Dec. 5 at 3:05 PM
$APLS I'm always so surprised when this stock is miraculously green
1 · Reply
ronaldo7
ronaldo7 Dec. 5 at 12:05 PM
1 · Reply
4Reel
4Reel Dec. 4 at 5:31 PM
$APLS damn thought this was the big green candle we needed to break 200sma 21.99, yet it lost half its gains already today, at least it shoes there is some buyers out there since it exhausted all retail. A close over 22 is what we want to see today and a hold tomorrow
1 · Reply
nevermind889
nevermind889 Dec. 4 at 3:58 PM
$APLT $APLX $APLD Nice gains today! Team APL!!! $APLS
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Dec. 4 at 3:47 PM
$APLS something like this>
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Dec. 4 at 3:47 PM
0 · Reply
scott52
scott52 Dec. 4 at 3:24 PM
$APLS Muhammad had Buraq, a winged donkey that flew him around, even taking him to the heavens and back where he met Adam, Jesus, Moses, Abraham, and God sitting on his throne. In some traditions Buraq was described as having the head of a woman and the tail of a peacock. Cedric needs a flying donkey to get this stock off the ground. Just saying.
0 · Reply