Market Cap 3.45B
Revenue (ttm) 781.37M
Net Income (ttm) -197.88M
EPS (ttm) N/A
PE Ratio 88.06
Forward PE N/A
Profit Margin -25.32%
Debt to Equity Ratio 1.13
Volume 4,009,700
Avg Vol 2,713,090
Day's Range N/A - N/A
Shares Out 126.53M
Stochastic %K 96%
Beta 0.31
Analysts Sell
Price Target $35.00

Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproli...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 977 5700
Website: apellis.com
Address:
100 Fifth Avenue, Waltham, United States
Jockne40
Jockne40 Jan. 11 at 6:09 PM
$APLS merger target for multiple drugs that are growing
1 · Reply
mikesterz7
mikesterz7 Jan. 11 at 4:13 AM
1 · Reply
philosophernutz
philosophernutz Jan. 11 at 3:51 AM
$APLS 🚨ALL WE NEED IS FOR CEDRIC TO USE THE GALE STUDY FOR EU APPROVAL. 1. The Canada "Withdrawal" Was a Tactical Move 🇨🇦 The Strategy: By pulling the application, they kept the door open. They didn't "fail"; they chose to pause until they had the 5-Year GALE Data (released Jan 2026) which provides the "clinically meaningful" evidence regulators were demanding. The Reload: Watch for Cedric to signal a re-filing in Canada using this massive 60-month dataset. This turns a "withdrawal" into a "delayed victory." 2. GALE: The Ace Card for UK & EU Re-Entry 🇬🇧 🇪🇺 The FUD: The MHRA (UK) and EMA (EU) previously said the drug slowed lesions but didn't prove it saved vision long-term. The Kill Shot: The January 2026 GALE update proves SYFOVRE delayed GA progression by ~1.5 years over a 5-year period. If the market realizes the EU and Canada are back on the table, the $33.94 price target becomes the floor, not the ceiling.
0 · Reply
philosophernutz
philosophernutz Jan. 11 at 3:30 AM
$APLS : 🏹 APLS: The "Guidance" Trap & The JPM Reality Check The bears are chirping about "no guidance." Let’s correct the record before Cedric takes the stage Monday at 11:15 AM PT. 1. Why "No Guidance" is the Ultimate Bear Trap Cedric Francois doesn’t provide formal guidance because APLS is a hyper-growth engine, not a legacy pharma company. The Strategic Advantage: By not capping expectations with a "conservative" number, Cedric leaves the door open for massive beats. The shorts are betting on a "miss," but they’re ignoring the $178M in U.S. net product sales already on the books. 2. EMPAVELI: The New Revenue Pillar Bears are still stuck on SYFOVRE safety from 2023. They’re ignoring the July 2025 FDA approval for EMPAVELI in C3G/IC-MPGN. Every 1,000 patients in this rare kidney space represents ~$500M in revenue. The Result: If Cedric even hints at the 2026 adoption rate of EMPAVELI being ahead of schedule, the shorts have zero protection.
0 · Reply
UgoGreg
UgoGreg Jan. 10 at 4:37 PM
$APLS https://youtu.be/ygBN8MilTyc
0 · Reply
love_bioatla
love_bioatla Jan. 10 at 6:45 AM
$APLS apls is love
1 · Reply
love_bioatla
love_bioatla Jan. 10 at 6:45 AM
$APLS full buying
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Jan. 9 at 9:51 PM
$APLS the end of today was the most buying I have seen in 1 year.
0 · Reply
4Reel
4Reel Jan. 9 at 9:27 PM
$APLS clear breakout for thoae holding, it was only a matter of time
1 · Reply
JFais
JFais Jan. 8 at 8:19 PM
Love indications where peak sales keep getting raised (opportunity underestimated as diagnosis rates go up) $XBI $LQDA: PH-ILD will surprise many into 2030+ $APLS: Empaveli bigger than ppl realize (FOMO kicking in for pediatric pats + LT data points to safety advantage in PNH)
1 · Reply
Latest News on APLS
Apellis Pharmaceuticals: The Picture Becomes Clearer

Aug 1, 2025, 2:29 PM EDT - 5 months ago

Apellis Pharmaceuticals: The Picture Becomes Clearer


Apellis Pharmaceuticals: Have Some Patience

May 20, 2025, 9:28 AM EDT - 8 months ago

Apellis Pharmaceuticals: Have Some Patience


Apellis Announces Craig Wheeler to Join the Board of Directors

Apr 21, 2025, 7:00 AM EDT - 9 months ago

Apellis Announces Craig Wheeler to Join the Board of Directors


FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals

Apr 1, 2025, 2:11 PM EDT - 10 months ago

FDA Reviews Kidney Disease Drug From Apellis Pharmaceuticals


Apellis Pharmaceuticals: A Mixed Bag

Mar 5, 2025, 2:06 PM EST - 11 months ago

Apellis Pharmaceuticals: A Mixed Bag


Jockne40
Jockne40 Jan. 11 at 6:09 PM
$APLS merger target for multiple drugs that are growing
1 · Reply
mikesterz7
mikesterz7 Jan. 11 at 4:13 AM
1 · Reply
philosophernutz
philosophernutz Jan. 11 at 3:51 AM
$APLS 🚨ALL WE NEED IS FOR CEDRIC TO USE THE GALE STUDY FOR EU APPROVAL. 1. The Canada "Withdrawal" Was a Tactical Move 🇨🇦 The Strategy: By pulling the application, they kept the door open. They didn't "fail"; they chose to pause until they had the 5-Year GALE Data (released Jan 2026) which provides the "clinically meaningful" evidence regulators were demanding. The Reload: Watch for Cedric to signal a re-filing in Canada using this massive 60-month dataset. This turns a "withdrawal" into a "delayed victory." 2. GALE: The Ace Card for UK & EU Re-Entry 🇬🇧 🇪🇺 The FUD: The MHRA (UK) and EMA (EU) previously said the drug slowed lesions but didn't prove it saved vision long-term. The Kill Shot: The January 2026 GALE update proves SYFOVRE delayed GA progression by ~1.5 years over a 5-year period. If the market realizes the EU and Canada are back on the table, the $33.94 price target becomes the floor, not the ceiling.
0 · Reply
philosophernutz
philosophernutz Jan. 11 at 3:30 AM
$APLS : 🏹 APLS: The "Guidance" Trap & The JPM Reality Check The bears are chirping about "no guidance." Let’s correct the record before Cedric takes the stage Monday at 11:15 AM PT. 1. Why "No Guidance" is the Ultimate Bear Trap Cedric Francois doesn’t provide formal guidance because APLS is a hyper-growth engine, not a legacy pharma company. The Strategic Advantage: By not capping expectations with a "conservative" number, Cedric leaves the door open for massive beats. The shorts are betting on a "miss," but they’re ignoring the $178M in U.S. net product sales already on the books. 2. EMPAVELI: The New Revenue Pillar Bears are still stuck on SYFOVRE safety from 2023. They’re ignoring the July 2025 FDA approval for EMPAVELI in C3G/IC-MPGN. Every 1,000 patients in this rare kidney space represents ~$500M in revenue. The Result: If Cedric even hints at the 2026 adoption rate of EMPAVELI being ahead of schedule, the shorts have zero protection.
0 · Reply
UgoGreg
UgoGreg Jan. 10 at 4:37 PM
$APLS https://youtu.be/ygBN8MilTyc
0 · Reply
love_bioatla
love_bioatla Jan. 10 at 6:45 AM
$APLS apls is love
1 · Reply
love_bioatla
love_bioatla Jan. 10 at 6:45 AM
$APLS full buying
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Jan. 9 at 9:51 PM
$APLS the end of today was the most buying I have seen in 1 year.
0 · Reply
4Reel
4Reel Jan. 9 at 9:27 PM
$APLS clear breakout for thoae holding, it was only a matter of time
1 · Reply
JFais
JFais Jan. 8 at 8:19 PM
Love indications where peak sales keep getting raised (opportunity underestimated as diagnosis rates go up) $XBI $LQDA: PH-ILD will surprise many into 2030+ $APLS: Empaveli bigger than ppl realize (FOMO kicking in for pediatric pats + LT data points to safety advantage in PNH)
1 · Reply
JFais
JFais Jan. 8 at 5:18 PM
$APLS- $5B buyout for Empaveli feels about right
0 · Reply
4Reel
4Reel Jan. 7 at 7:56 PM
$APLS and im all out finally at 26. Thank you for the green day , still bullish just moving this money to other plays
1 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Jan. 7 at 4:16 PM
$APLS Please do all of us a favor and take the offer...
1 · Reply
4Reel
4Reel Jan. 7 at 2:55 PM
$APLS well thats good news, still holding some to see if chart plays out
0 · Reply
Starlord10
Starlord10 Jan. 7 at 2:07 PM
$APLS Would love to be in a number of different stocks, but the minute I sell this thing, it’s gonna be acquired.
0 · Reply
UgoGreg
UgoGreg Jan. 6 at 11:29 PM
$APLS https://youtu.be/ygBN8MilTyc
0 · Reply
Jennifur
Jennifur Jan. 6 at 8:47 PM
$APLS this company stock absolutely adores stinking it up all over Wall Street when the market rallies
1 · Reply
4Reel
4Reel Jan. 6 at 8:04 PM
$APLS selling over half my position way too much easy money to be made elsewhere, someone got a homd of it the last 2 days and took it down 9% on 2 big green days. Im making a lot more elsewhere
2 · Reply
4Reel
4Reel Jan. 6 at 7:10 PM
$APLS 400 puts at 25 dollars today was bought at early. Only 549 options today total. Same thing happened yesterday and the stock also went down almost 4% 2 days in a Row with the same stock price result. Essentially someone short 40k shares, 400×100. Terrible volume today too. A ton of power on them little puts especially when XBI is 1.2% up and the market hit new all time high today. No call volume is hurting, but im still holding
0 · Reply
Whiskeyunderthebed
Whiskeyunderthebed Jan. 6 at 6:19 PM
$APLS kiss of death... nothing changes.
0 · Reply
4Reel
4Reel Jan. 6 at 4:18 PM
$APLS wheres the buyout at? Uve exhausted every retail and only a handful of us left here.
0 · Reply
APLD_SQUEEZE_PT_99
APLD_SQUEEZE_PT_99 Jan. 6 at 2:56 PM
$UNH cute but $APLS
0 · Reply