Jul. 1 at 11:10 AM
$ADAG $SNY Adagene announces up to
$25M strategic investment from Sanofi
Adagene (ADAG) announced strategic investment and option exercise by Sanofi (SNY). Sanofi has agreed to make strategic investment of up to
$25M in Adagene. The Company plans to use the proceeds to fund its research and development activities, including clinical development of muzastotug, an anti-CTLA-4 SAFEbody, through a randomized phase 2 trial in microsatellite stable colorectal cancer, MSS CRC. To further explore the clinical potential of muzastotug, Adagene will supply Sanofi with muzastotug to evaluate the safety, efficacy, pharmacokinetics and biomarker data in combination with other anticancer therapies in over 100 patients in a phase 1/2 clinical trial in advanced solid tumors.
Adagene continues to own worldwide commercial rights to muzastotug. Sanofi has also exercised its option to select a third SAFEbody discovery program, utilizing Adagene's proprietary masking technology and antibody engineering expertise. The bispecific therapeutic, with undisclosed targets, will be engineered by Adagene and induces an option exercise fee, as well as milestones and royalties as per the 2022 partnership agreement with Adagene.
As of December 31, 2024, the Company had audited cash and cash equivalents of US
$85.2 million. The proceeds from the investment of Sanofi, together with the current cash and cash equivalents, are expected to be sufficient to fund planned operations into 2027.
