Market Cap 40.20M
Revenue (ttm) 0.00
Net Income (ttm) -22.23M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 846,200
Avg Vol 180,430
Day's Range N/A - N/A
Shares Out 23.93M
Stochastic %K 0%
Beta 0.52
Analysts Strong Sell
Price Target $10.00

Company Profile

Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancers in the United States. The company's lead product candidate is elraglusib injection, a glycogen synthase kinase-3 inhibitor that is in Phase 2 trial to treat metastatic pancreatic ductal adenocarcinoma. It also develops elraglusib, which is in Phase 1/2 trial for the treatment of refractory pediatric malignancies, including Ewing sarcoma, as well as neuroblastoma and pediatric l...

Industry: Biotechnology
Sector: Healthcare
Phone: 817 887 8455
Address:
1751 River Run, Suite 400, Fort Worth, United States
bullweevil
bullweevil Jun. 23 at 5:43 AM
$ACTU Only 160 watchers! Consinsus strong buy by analysts even with their financial issues. Why? Because their drug has had very successful phase 2 trials with adults. More results coming this year. How do they keep funding? Actuate officially established a $100 million at-the-market (ATM) equity sales agreement. According to the company's SEC 10-K filing, they did not sell any shares under this program through the end of 2025, leaving the full $100 million in remaining capacity intact moving into recent quarters. However, they have recently chosen to use traditional structured underwritten public offerings to secure immediate cash. The coming probable dilution is factored into the price and also into the price target of over $9. By the way, they have a good chance to get an FDA Rare Pediatric Disease Priority Review Voucher (PRV). This is a couple years away, but if they do get it they could sell it to a large pharmaceutical company for $150 to $200 million!
2 · Reply
justiceforb_85
justiceforb_85 Jun. 9 at 5:30 PM
$ACTU signs of life on this one! Glad to see they are proceeding with elraglusib studies.
0 · Reply
focafoca99
focafoca99 Jun. 9 at 12:04 PM
$ACTU selected its elraglusib program for evaluation in the BEACON2 pediatric neuroblastoma trial.
0 · Reply
justiceforb_85
justiceforb_85 Jun. 3 at 3:03 AM
$ACTU company is running low on cash and time. Needs to get the data of combo with RASi out quickly.
0 · Reply
Merlintrader
Merlintrader Jun. 2 at 6:39 AM
$IMTX ASCO 2026 Oncology Signals, Part Two: $IMTX, $ACTU and $BCTX Highlight Three Higher-Risk Cancer Stories Beyond the Headline Data https://www.merlintrader.com/asco-2026-oncology-signals-part2-imtx-actu-bctx/
0 · Reply
justiceforb_85
justiceforb_85 May. 15 at 10:44 PM
$ACTU company has an active drug with elraglusib but a precarious cash position lasting until July. How does the company plan to move forward?
2 · Reply
justiceforb_85
justiceforb_85 May. 13 at 1:56 AM
$ACTU positive developments include oral formulation of elraglusib. If there is preclinical evidence for synergy with RAS inhibitors, the company would be on significantly better footing. Ewings signal is real but TAM quite small.
0 · Reply
focafoca99
focafoca99 May. 12 at 1:53 AM
$ACTU kicks off its IND FDA clearance to begin a Phase 1/2 study of elraglusib.
0 · Reply
justiceforb_85
justiceforb_85 May. 11 at 8:01 PM
$ACTU absurd drop. Added. Look forward to oral erlaglusib and preclinical data with RAS inhibitors.
0 · Reply
ggabel7
ggabel7 May. 11 at 7:38 PM
how come retail didn’t see $ACTU FDA news today ? volume will come $MRAM $NVTS $INTC $NOK
0 · Reply
Latest News on ACTU
Actuate Therapeutics Quarterly report: Q1 2026

May 14, 2026, 8:00 AM EDT - 6 weeks ago

Actuate Therapeutics Quarterly report: Q1 2026


Actuate Therapeutics Proxy statement: Proxy filing

May 6, 2026, 8:00 AM EDT - 7 weeks ago

Actuate Therapeutics Proxy statement: Proxy filing


Actuate Therapeutics management to meet with  B. Riley

2026-04-30T16:41:48.000Z - 2 months ago

Actuate Therapeutics management to meet with B. Riley


Actuate Therapeutics Proxy statement: Proxy filing

Apr 6, 2026, 8:00 AM EDT - 2 months ago

Actuate Therapeutics Proxy statement: Proxy filing


Actuate Therapeutics Proxy statement: Proxy filing

Apr 6, 2026, 8:00 AM EDT - 2 months ago

Actuate Therapeutics Proxy statement: Proxy filing


Actuate Therapeutics Annual report: Q4 2025

Mar 26, 2026, 8:00 AM EDT - 3 months ago

Actuate Therapeutics Annual report: Q4 2025


Actuate Therapeutics says Phase 2 study met primary endpoints

2026-01-12T13:51:27.000Z - 5 months ago

Actuate Therapeutics says Phase 2 study met primary endpoints


Actuate Therapeutics Quarterly report: Q3 2025

Nov 13, 2025, 7:00 AM EST - 8 months ago

Actuate Therapeutics Quarterly report: Q3 2025


Actuate Therapeutics 2.142M share Secondary priced at $7.00

2025-09-10T12:35:09.000Z - 10 months ago

Actuate Therapeutics 2.142M share Secondary priced at $7.00


Actuate Therapeutics files $250M mixed securities shelf

2025-09-02T20:35:57.000Z - 10 months ago

Actuate Therapeutics files $250M mixed securities shelf


Actuate Therapeutics Registration statement: Registration filing

Sep 2, 2025, 8:00 AM EDT - 10 months ago

Actuate Therapeutics Registration statement: Registration filing


Actuate Therapeutics initiated with a Buy at B. Riley

2025-08-26T08:45:11.000Z - 10 months ago

Actuate Therapeutics initiated with a Buy at B. Riley


Actuate Therapeutics Quarterly report: Q2 2025

Aug 14, 2025, 8:00 AM EDT - 11 months ago

Actuate Therapeutics Quarterly report: Q2 2025


Actuate Therapeutics Transcript: Study update

May 31, 2025, 7:30 PM EDT - 1 year ago

Actuate Therapeutics Transcript: Study update


Actuate Therapeutics Press release: Study update

May 31, 2025, 7:30 PM EDT - 1 year ago

Actuate Therapeutics Press release: Study update


Actuate Therapeutics Quarterly report: Q1 2025

May 15, 2025, 8:00 AM EDT - 1 year ago

Actuate Therapeutics Quarterly report: Q1 2025


Actuate Therapeutics Proxy statement: Proxy filing

Apr 9, 2025, 8:00 AM EDT - 1 year ago

Actuate Therapeutics Proxy statement: Proxy filing


Actuate Therapeutics Proxy statement: Proxy filing

Apr 8, 2025, 8:00 AM EDT - 1 year ago

Actuate Therapeutics Proxy statement: Proxy filing


Actuate Therapeutics Annual report: Q4 2024

Mar 13, 2025, 8:00 AM EDT - 1 year ago

Actuate Therapeutics Annual report: Q4 2024


Actuate Therapeutics Quarterly report: Q3 2024

Nov 13, 2024, 7:00 AM EST - 1 year ago

Actuate Therapeutics Quarterly report: Q3 2024


Actuate Therapeutics Quarterly report: Q2 2024

Sep 24, 2024, 8:00 AM EDT - 1 year ago

Actuate Therapeutics Quarterly report: Q2 2024


bullweevil
bullweevil Jun. 23 at 5:43 AM
$ACTU Only 160 watchers! Consinsus strong buy by analysts even with their financial issues. Why? Because their drug has had very successful phase 2 trials with adults. More results coming this year. How do they keep funding? Actuate officially established a $100 million at-the-market (ATM) equity sales agreement. According to the company's SEC 10-K filing, they did not sell any shares under this program through the end of 2025, leaving the full $100 million in remaining capacity intact moving into recent quarters. However, they have recently chosen to use traditional structured underwritten public offerings to secure immediate cash. The coming probable dilution is factored into the price and also into the price target of over $9. By the way, they have a good chance to get an FDA Rare Pediatric Disease Priority Review Voucher (PRV). This is a couple years away, but if they do get it they could sell it to a large pharmaceutical company for $150 to $200 million!
2 · Reply
justiceforb_85
justiceforb_85 Jun. 9 at 5:30 PM
$ACTU signs of life on this one! Glad to see they are proceeding with elraglusib studies.
0 · Reply
focafoca99
focafoca99 Jun. 9 at 12:04 PM
$ACTU selected its elraglusib program for evaluation in the BEACON2 pediatric neuroblastoma trial.
0 · Reply
justiceforb_85
justiceforb_85 Jun. 3 at 3:03 AM
$ACTU company is running low on cash and time. Needs to get the data of combo with RASi out quickly.
0 · Reply
Merlintrader
Merlintrader Jun. 2 at 6:39 AM
$IMTX ASCO 2026 Oncology Signals, Part Two: $IMTX, $ACTU and $BCTX Highlight Three Higher-Risk Cancer Stories Beyond the Headline Data https://www.merlintrader.com/asco-2026-oncology-signals-part2-imtx-actu-bctx/
0 · Reply
justiceforb_85
justiceforb_85 May. 15 at 10:44 PM
$ACTU company has an active drug with elraglusib but a precarious cash position lasting until July. How does the company plan to move forward?
2 · Reply
justiceforb_85
justiceforb_85 May. 13 at 1:56 AM
$ACTU positive developments include oral formulation of elraglusib. If there is preclinical evidence for synergy with RAS inhibitors, the company would be on significantly better footing. Ewings signal is real but TAM quite small.
0 · Reply
focafoca99
focafoca99 May. 12 at 1:53 AM
$ACTU kicks off its IND FDA clearance to begin a Phase 1/2 study of elraglusib.
0 · Reply
justiceforb_85
justiceforb_85 May. 11 at 8:01 PM
$ACTU absurd drop. Added. Look forward to oral erlaglusib and preclinical data with RAS inhibitors.
0 · Reply
ggabel7
ggabel7 May. 11 at 7:38 PM
how come retail didn’t see $ACTU FDA news today ? volume will come $MRAM $NVTS $INTC $NOK
0 · Reply
ggabel7
ggabel7 May. 11 at 7:36 PM
wow looks like retail did see the fra news today and HCWainwright reiterates buy ratting for $ACTU volume will send it let’s see what happens $MRNA $IREN $JNJ $MRK
0 · Reply
Dan8406
Dan8406 May. 9 at 1:50 PM
$ACTU Just a few things about Dr. Huber! ​Dr. Huber has over two decades of experience in the biotechnology sector and has successfully overseen several corporate acquisitions: ​Mersana Therapeutics: He served as the President and CEO of the company from 2023 until January 2026, when the firm was acquired by Day One Pharmaceuticals. ​TESARO: He worked here as Chief Medical Officer. Following the acquisition of the company by GlaxoSmithKline (GSK) in 2019, Huber continued to lead clinical development as Vice President. ​Merck: Between 2012 and 2015, he served as Vice President responsible for oncology clinical research. ​Academic background: He began his career as an Assistant Professor at one of the world's leading cancer research centers, the M.D. Anderson Cancer Center in Texas.
0 · Reply
justiceforb_85
justiceforb_85 May. 6 at 9:24 PM
$ACTU do we have any other monotherapy data for elraglusib aside from this prior study (https://aacrjournals.org/clincancerres/article-abstract/30/3/522/733553/Phase-I-Study-of-Elraglusib-9-ING-41-a-Glycogen?redirectedFrom=fulltext)? Combination with GnP for PDAC appears promising though with $RVMD future care would likely involve combining elraglusib with a RAS inhibitor.
0 · Reply
focafoca99
focafoca99 May. 6 at 2:26 PM
$ACTU assigned Dr. Huber to its board, expanding the directors to eight.
1 · Reply
crimsonsunglo
crimsonsunglo Apr. 28 at 3:31 PM
$ACTU moving up on low volume.
0 · Reply
BiotechButterflies
BiotechButterflies Apr. 22 at 8:23 PM
$ACTU a very intriguing set-up here - I'v gotten in!
0 · Reply
Rolo2024
Rolo2024 Apr. 19 at 12:57 AM
$ACTU Biggest worry is the cash burn rate. Only have cash on hand to run until July of 2026. Results are are promising but looks like a stock offering will happen this summer. I might wait until this plays out before buying some shares. I hate dilution.
1 · Reply
RadioIsotope25
RadioIsotope25 Apr. 15 at 11:44 AM
0 · Reply
papibaro
papibaro Apr. 15 at 3:38 AM
$ACTU new to this stock. saw today’s news. Seemed very positive. Plus, pancreatic cancer is potentially a huge opportunity. For those know the company better, how are their management, finances, and history? Do they have a history of diluting?
0 · Reply
LewisDaKat
LewisDaKat Apr. 14 at 7:30 PM
$ACTU Actuate Therapeutics Announces Nature Medicine Publication of Clinical Trial Results Showing Doubling of the Rate of Survival with Elraglusib Plus Chemotherapy in Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma https://marketwirenews.com/stock/actu/news/actuate-therapeutics-announces-nature-medicine-publi-6349215341264352.html?utm_source=stocktwits
0 · Reply
BioTuesdays
BioTuesdays Apr. 14 at 2:23 PM
$ACTU has announced the publication of new data in Nature Medicine from its Phase 2 clinical trial evaluating elraglusib in combination with the gemcitabine-Nab-paclitaxel (GnP) chemotherapy compared to GnP alone in patients with previously untreated metastatic pancreatic cancer (mPC). https://biotuesdays.com/2026/04/14/nature-medicine-publishes-actuates-data-from-trial-of-elraglusib-chemo-in-mpc/
0 · Reply
TA_Kongen
TA_Kongen Apr. 14 at 2:06 PM
$ACTU Long 2 flat. Decent size.
0 · Reply